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Role of Gandhak Murchit Parad Kalpa (HgS) on Agnimandya - A Critical

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 229

ISBN 978-93-5137-179-3 ISSN 2320-7329

978-93-5137-179-3

National Journal of Reseach in Ayurved Science

Title of Article “ Role of Gandhak Murchit Parad Kalpa (HgS)

on Agnimandya - A Critical Review

”
TECHNOLOGY

1 2
Manali Shashikant Kulkarni* , Piyush K. Gandhi
1. PG scholar,
2. Guide

Rasashastra & Bhaishajyakalpana

PDEA’s College of Ayurveda and Research Centre, Nigdi, Pune- 44
* Corresponding author: E-mail: mani.kool2021@gmail.com; Phone Number: 8983380382

ABSTRACT:
Ayurveda, the ancient Indian Medicine system of life science has given prime importance to
Agni, which represents digestive and metabolic fire in the body. Imbalance of Jatharagni imabalanced
the Bhutagni and Dhatwagni which eventually disturbs digestive system and give rise to state called
‘Agnimandya’, Murchana is a process without Parad (Mercury) does not attains medicinal quality.
This concept is based on prime diseases caused by Agnimandya like Jwara, Grahani, Prameha.
corresponding to treatment of Rasaaushadhi containing Kajjali, Parpati, Rasasindur, Pottali Kalpas
and Hingul Kalpas. The literary review of murchit parad kalpa from Bhaishajya ratnavali states that
role of HgS differs by its preparatory method and mode of action as Hingul is best as
Jwaraghana,Parpati is meant for Grahani ,Rasasindura improves state in prameha and Kajjali enhances
properties of rasaushadhi with yogavahi and rasayan quality.

KEYWORD: Murchana, Parad Kalpa, Agnimandya

http://www.ayurlog.com A YUR L OG | Vol. 5th , Issue 3rd : April-June 2017

INTRODUTION: 1. MATERIALS AND METHODS:-
This concept is based on prime diseases
Ayurveda, the ancient Indian Medicine
caused by Agnimandya like Jwara, Grahani,
system of life science has given prime
Prameha. These peculiar differentiation of
importance to Agni, which represents
diseases is according to Samprapti , place
digestive and metabolic fire in the body.
and type of Agni corresponding to treatment
Acharya have mentioned when Agni is
of Rasaaushadhi containing Kajjali, Parpati,
proper , is said to be a sign of ‘Prashta
Rasasindur, Pottali Kalpas and Hingul
(1)
Purush’ .Thirteen types of Agni are
Kalpas. The literary review is from
mentioned in Ayurvedic classics, classified
Brihatrayi, Bhaishajya Ratnavali and distinct
as Jatharagni, Bhutagni and Dhatwagni.
Rasashastra granthas.
Imbalance of Jatharagni imabalanced the
1.1. Diseases caused by Agnimandya
Bhutagni and Dhatwagni which eventually
Acharya Vagbhata says Mandagni is
disturbs digestive system and give rise to (2)
responsible for all diseases. Jatharagni is
state called ‘Agnimandya’, which is a root
the combination of Saman Vata,Pachak Pitta
cause of diseases like Jwara, Atisara,
and Kledak kapha.When any out of these
Grahani,Pandu.For better health correction
gets impaired due to inappropriate diet
of Agni by precise treatment is a necessity.
affects further process of metabolism
Rasa Chikitsa (Mercury and its compounds) corresponding to Dhatwagnimandya and
is a back bone of Ayurvedic Alchemy for Bhutagnimandya. According to place of
curing various diseases. Murchana is a accumulation of vitiated dosha and
process without Parad (Mercury) does not agnimandya evaluation of numerous
attains medicinal quality. Murchana diseases occurs.
preparations are with or without Sulphur .In
these , Mercury is converted into compound
form such as Kajjali, Rasasindur, Parpati,
Pottali etc Rasayana. Every Murchita Parad
Kalpa has its own significance due to its
method of preparation and mode of action.
Though all these are chemically same (HgS
- Mercuric Sulphide)

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231

Table no 1. Diseases caused by Agnimandya

Sr no Type of agnimandya Name of disease Vyadhi adhisthan

1 Jatharagnimandya Jwar Amashaya
2 Jatharagnimandya Grahani Laghwantra
Dhatwagnimandya
3 Dhatwagnimandya Prameha Vrukka

1.2. Gandhak Murchita Parad Kalpa (Mercuric Sulphide HgS)

Hingul Gandhak Murchit Parad Kalpa

Khalwi rasayana Kupipakwa rasayana Parpati rasayana Potali rasayana

Kajjali Rasasindura Rasaparpati Rasapottali

Gandhak Murchita Parad Kalpa prepared. Hingul is a mineral naturally

Murchana a process , which converts
Parada capable for medicinal use, further
subdivided as Sagandha (with sulfur) and
Nirgandha (without sulfur) .In comparison,
Sagandha Murchana are considered to be
safe and non toxic.When gandhaka and
parada are mixed uniformly,they form a
black powder known as Kajjali. From the
kajjali, many secondary derivatives like
parpati, Rasasindura ,pottali can be
Table no 4. Properties of Murchit parad Kalpa
contains mercury and sulfur . These all
formulations are proven to be chemically
same, but the mode of action varies from
each other because of preparatory
variation. All these Mercuric sulphide
(HgS) have their own significant role in
the management of following diseases
caused by agnimandya
1.3. Properties of Murchit Parad
Kalpa

Sr. No. Kalpa Rasa Virya,vipaka Guna,Karma Indication

1 Hingul (3) Tikta, Ushna, Dipan, Kaphapah,
Kashay Madhur Rasayan Jwara
aampachak
2 Kajjali (4) Katu, Ushna,Katu Sara,guru Tridoshshamak
Tikta
3 Parpati (5) shadras Ushna,katu Laghu,Adhogami, Grahani,
grahi Jalodar
4 Rasasindura(6) Katu Ushna ,Katu Laghu, Prameha,
urdhwagami Shwas
Ruksha, sukshma
strotogami
231 | Page | Ayurlog: NJRAS | Vol. 5 | AYURLO G | Vol. 5th , Issue 3rd : April-June 2017
1.4. Murchit Parad Kalpa used in Agnimandya diseases

Table 3. Murchit Parad Kalpa in agnimandya

Disease Kajjal Hingu Rasa Parpat Pottal Kajjaliyukt Gandha Rasa Tota
name i l sindur i i a k Sindur l
kalpa kalpa a kalpa kalpa Hingul Yukta a kalp
kalpa kalpa hingul kajjali a
kalpa kalpa
Jwara 95 20 12 - - 18 - 3 148
Grahani 27 1 1 5 1 1 1 - 37
Prameh 13 - 13 - - - - - 26
a

2. OBSERVATION management of jwara. Whereas in Grahani

1) Jwara : only five parpati kalpas were found and
2) a) Hingul Kalpa – 20 kajjali used often in kharaliya kalpa.
b) Kajjali Yukta Hingul Kalpa – 18 Though parpati is meant for Grahani
diseases it has some limitation and it may
2) Grahani : a) Parpati Kalpa–5
suggest that the role of parpati in grahani
b) Kajjali Kalpa - 27 is limited or might be for chronic or
particular vyadhi avastha. In Prameha,
3) Prameha : a) Rasasindura Kalpa – 13
Rasasindura kalpa are equally contributed
b) Kajjali Kalpa - 13 as much as Kajjali yogas.

4. DISSCUSSION Role of Hingul And Kajjali in Jwara

Jwara, Grahani, Prameha are prime In Jwara prakupit dosha are descended into
diseases caused by vitiated agni that is amashaya where they debilitated
Agnimandya. Anatomically and Jatharagni from its place and body
physiologically granthakaras have temperature rises. The onset of Jwara is
explained the samprapti of these diseases because of apakwa mala and aam
in detail. Bhaishajya Ratnavali is a text extending in strotorodh. Parad gandhak
containing compiled of all medicaments kajjali is is yogvahi and sara hence
corresponding to particular diseases. In the participates in amapachan and
literary review of Bhaishajya ratnavali it malapravrtana ,Where Hingul is deepan
was found that Hingul and kajjali yukta ,ampachak act specifically on amashayaby
hingul kalpas are often used in the improving strotorodh by tikta katu and

232 | Page | Ayurlog: NJRAS | Vol. 5 | AYURLO G | Vol. 5th , Issue 3rd : April-June 2017
ushna guna. Here kajjali is a niragni parad
murchana,due to lack of agnisamskara it is
sara though guru in nature but when
collaborates with Hingul acts as best
jwaraghna due to its yogavahi property.
While preparing kajjali this trituration
process significantly reduced the particle
size and therefore becomes more
biocompatible and it passes large stay in
intestinal mucosa. (7)
Role of Parpati in Grahani
Grahani is a place of Agni.(8) It holds the
digested food descended from amashaya.
Here panchabhutagni and dhatwagni
absorbs and metabolized the extract part of
it. Etiopathognesis of Grahani vyadhi
includes taking non beneficial diet by
person recovering from diarrhea with poor
digestive capacity. Restoration of Agni is
the principle concern in the management
of Grahani Roga. Parpati is pota bandha of
parad while giving heat to kajjali it breaks
down into small particles and bond gets
strong here which don’t allow parpati to
absorbs easily in the amashaya but
specifically on pakwashaya and grahani as
Parpati has grahi and adhogami
property.The media like cow dung and
green leaf enhance the activity of parpati.
(9).
During heat process cow’s bile and leaf
excretes bilious product and chlorophyll
which helps in correcting Agni. It is a
significance of parparti kalpana in grahani.
233 | Page | Ayurlog: NJRAS | Vol. 5 | AYURLO G | Vol. 5th , Issue 3rd : April-June 2017
Kajjali kalpa here plays Pachan role in
samavastha and parpati is meant to cure
grahani in niramavastha (10)
Role of Rasasindura in Prameha
Acharya Sushruta had mentioned the root
cause of Prameha occurs due to apkwa
Vata Pitta , Kapha dosha . Prameha
pathogenesis is by dhatwagnimandya
specifically Medodhatwagnimandya.
Failure in nourishment of dhatu portraits
dhatukshaya or dhatuvriddhi. Prameha is
diagnosed with frequent micturation
denotes loosen capacity of vrukka made up
of meda and rakta.
Medodhatwagnimandya resembles to large
production of kleda apparently increased
in mutrapravruti. Amongst all kajjali
preparation ,Rasasindur is very different
due to durability and gradual pattern of
heat for 24 hours.As an impact of it
Rasasindur becomes more tikshna, tivra
and sukshma strotogami . Few Chemical
analysis of it had proven that macro
particle size of the drug matches well with
colloidal size and suggests the possibility
of colloidal particles are get attached to
human intestine and provide large surface
area.(11). This concept explore the mode of
action by correlating it with correction of
dhatwagnimandya and bhutagnimandya
.Overall though murchit kalpa contains
same HgS formula ,every kalpa
participates in improvisation of
agnimandya on its individual property. It is 4. Shri Sadananda Sharma. Rasa
also proved that HgS is more soluble in the Tarangini. Edited by Pandith Kashinath
gastrointestinal (GI) tract due to the action Shastry, 11th edition New Delhi: Motilal
of digestive enzymes changing pH Banarasi Das Publication;1979. 5th
conditions therefore corrects agni and it’s Taranga, verses 112, 126.
diseases.(12) 5. Shri Sadananda Sharma. Rasa
Tarangini. Edited by Pandith Kashinath
5.CONCLUSION
Shastry, 11th edition New Delhi: Motilal
Gandhaka Murchita Parad Kalpas (HgS) Banarasi Das Publication;1979. 6th
holds its specialty in correcting Taranga, verses 140-142, 131.
agnimandya and diseases caused by it. 6. Shri Sadananda Sharma. Rasa
Tarangini. Edited by Pandith Kashinath
Use of particular Kalpa in particular
Shastry, 11th edition New Delhi: Motilal
agnimandya will not only eradicates
Banarasi Das Publication;1979. 6th
disease but put forward for enhancement
Taranga, verses 190-198, 140
of health.
7. K.S.Thakur et al.Evaluation of
REFERNECES structural , chemical characterization and
safety studies of Samagandhak Kajjali,an
1. Agnivesha.Charak Samhita Vol- I
Indian traditional Ayurvedic drug.Journal
Sutrasasthan Ashtoninditiya adhyay.Hindi
of pharmacognosy and phytochemistry
translation by Vidyadhar Shukla,Ravidutta
2014;2(16):57 -67.
Tripathi. Reprint: Chaukhamba
8. Agnivesha.Charak Samhita Vol- I
Pratishthan, 2009,verses 21/ 19,303
chikitsasthan grahanichikitsa adhyay.Hindi
2. Acharya
translation by Vidyadhar Shukla,Ravidutta
Vagbhata.Ashtanghridaytantram
Tripathi. Reprint: Chaukhamba
Nidansthan udarrogadhyay.Edited by Pt.
Pratishthan, 2009,verses 15/ 56-57,369
Harishastri.Reprint: Varanasi;
9. Murali krisna C et al.A prospective
Chaukhamba Surbharati Prakashan,2014,
study on Parpati kalpana w.s.r to
verses 12/1,513.
panchamrut parpati .IJAM,2010,1(3).118-
3. Shri Sadananda Sharma. Rasa
128.
Tarangini. Edited by Pandith Kashinath
10. Gangadhar Gune
Shastry, 11th edition New Delhi: Motilal
Shastri.Ayurvediya
Banarasi Das Publication;1979. 9th
Aushadhigundharmashastra. Reprint:
Taranga, verses 18-19, 202

234 | Page | Ayurlog: NJRAS | Vol. 5 | AYURLO G | Vol. 5th , Issue 3rd : April-June 2017
 Published by Vaidya Grantha Rasasindura.IJTK,Vol .8(3),July 2009. Pp
Bhandar;2008. 346 -351
11. Sunil 12. J.Arunachalam.Research on
K.Singh,A.K.Chaudhari,D.K.Rai.Preparati Mercurial preparation:The prime
on and characterization of mercury based requirement for their acceptance in
Indian traditional drug. – medical world.Ayu 2015;36:118-24.

Cite this article: Journal Website: www.ayurlog.com

Role of Gandhak Murchit Parad Kalpa (HgS) on Agnimandya - A Critical Review

Manali Shashikant Kulkarni, Piyush K. Gandhi
Source of Support: None, Conflict of Interest: None Received: March, 2017. Accepted: March, 2017
Ayurlog: National Journal of Research in Ayurved Science-2017 ;(5)(3) 229-235

235 | Page | Ayurlog: NJRAS | Vol. 5 | AYURLO G | Vol. 5th , Issue 3rd : April-June 2017

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