MIND MAPPING OSTEOSARKOMA

Osteosarcoma adalah sel mesenkim yang

ganas yang mempunyai kemampuan untuk ETIOLOGI
membentuk osteoid atau tulang yang
1. Trauma
imatur. 2. Karsinogenik
ekstrinsik
3. Karsinogenik
kimia
4. Virus
PEMERIKSAAN PENUNJANG onkogenik
5. Herediter
1. Biopsi
2. Pemeriksaan Darah
3. CT Scan & MRI
4. Bone Scan
5. Angiografi

Gejala umum

SUB CLASS • Adanya rasa sakit, ketika

OSTEOSARCOMA beraktifitas
• nyeri pada tulang pada saat
1. Osteolitik malam hari.
PENATALAKSANAAN
osteosarkoma • Sering terjatuh
2. Osteoblastik 1. Kemoterapi KOMPLIKASI • Bengkak, tergantung besar
osteosarkoma 2. Operasi dan lokasi lesi
3. Telangiektatik 3. Follow up post 1. Akibat langsung : Patah tulang
osteosarcoma 2. Akibat tidak langsung : Penurunan berat badan, Gejala sistemik
operasi
(kemoterapi) anemia, penurunan kekebalan tubuh
3. Akibat pengobatan : Gangguan saraf tepi, • Demam
penurunan kadar sel darah, kebotakan pada • Berkeringat pada malam
kemoterapi. hari
 T categories of bone cancer
T0: There is no evidence of a main (primary) tumor.
T1: The tumor is 8 cm (around 3 inches) across or less.
T2: The tumor is larger than 8 cm across.
T3: The tumor has “skipped” to another site or sites
within the same bone.
N categories of bone cancer
N0: The cancer has not spread to regional (nearby)
lymph nodes.
N1: The cancer has spread to nearby lymph nodes.
M categories of bone cancer
M0: There is no spread (metastasis) to distant organs.
M1a: The cancer has spread only to the lung.
M1b: The cancer has spread to other distant sites in the
body.
Grades of bone cancer
Note: The grades used for the AJCC system are
different from those in the MSTS system.
There are other differences between the systems as
well. To avoid confusion, it may help to
ask your (child’s) doctor which staging system he or
she uses.
GX: Grade can’t be assessed
G1, G2: Low grade
G3, G4: High grade

Stage IA
T1, N0, M0, G1 or G2 (or GX): The tumor is 8 cm across or less and is low grade (or the grade can’t be assessed). It has not spread to nearby lymph nodes or to distant parts of
the body.
Stage IB
T2-T3, N0, M0, G1 or G2 (or GX): The tumor is larger than 8 cm across or has “skipped” to other sites in the same bone. It is low grade (or the grade can’t be assessed). It has
not spread to nearby lymph nodes or to distant parts of the body.
Stage IIA
T1, N0, M0, G3 or G4: The tumor is 8 cm across or less and is high grade. It has not spread to nearby lymph nodes or to distant parts of the body.
Stage IIB
T2, N0, M0, G3 or G4: The tumor is larger than 8 cm across and is high grade. It has not spread to nearby lymph nodes or to distant parts of the body.
Stage III
T3, N0, M0, G3 or G4: The tumor has “skipped” to other sites in the same bone. It is high grade. It has not spread to nearby lymph nodes or to distant parts of the body.
Stage IVA
Any T, N0, M1a, any G: The tumor has spread only to the lungs. It has not spread to the
lymph nodes or to other distant sites. (It can be any size or grade.)
Stage IVB (if either of these applies)
Any T, N1, any M, any G: The tumor has spread to lymph nodes. It can be any size or
grade, and might or might not have spread to other distant sites.
Any T, any N, M1b, any G: The tumor has spread to distant sites other than the lung. It can
be any size or grade.