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lOMoARcPSD|19132033

Posology

Pharmacy (Rajiv Gandhi University of Health Sciences)

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alassmate
Dato
Pag

PosoLOGY
cocoosos mtaunS.
Po
raloa His derived: trom Greek
(
losdloay 13.dene
nomuch aaad logy aaeamg Scence' oitk how
AA abranch science ich deaks
is
much oammunl drug ortuthe quantity A dg
Ho be odnmanisteed in the lbddyi

tacto Atechhg the dbse


Age n childten the enzyme in. the livert nd

So al he
exceretian temaioless developeoli
Mendt ena
odult.
dose should be less than at
In caae aelderly patient,he reual dunctim
decline_anl nmetabäliamn the Iiverr als6 decrceaaesy
abseptiombecomeslouoerto e have to
dug
aiveaAministee yety less close
AAoarpiO.
DAisHilhon
M Metalb ism
Excrethm
.female
Sexln cane" s treatnaent oth sex hoxmsme
buks ttquires',mallete dosage an: male due
othe Poesence moce bddy ta.
pecio carte daould be toke åhle administeriug any
ag to a ooman h duug menstutcaio n,
pepnaneyamd lactatim,stmna purgative vhould nðl
beqenduitina tthose time
Anhesnalnut a pat jalkalaiels. should nát be taken
dudng poeginants do avrid deloxaiooi doefus.
AntikiStaane ol edative alaoiuld noi be. 'faken
dauuglackatisa becayse these_are Scceted in the

ewownefo autor

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lOMoARcPSD|19132033

Dote
Page

Bady soeakl he usual dosageo dugs


mentionès tor to Kg adultk
ne dag conentrahionai sie actionk
boaed a the ra hoa. betoen the amout
Sdg adminstered and the sae 4 the
bbdy
The do0se caleulation or abntrmall y tin
ortobesty airtsan.ate_reaureo to caltulate
nhe baaisd by eigd
bodi suace area Many pyúdlogytctor
Such aa plosmaGdlume Oxugen Conauphiom.
Owmd rteauurcemed bádyiaelectrites
Calpresnod gloterater gloneda
Hrahon ane propohisnal to the une

ExAnH cartruert daas ie mefiotrexate


Odm nisterned acmidiug to thebidy stase
9eyerity6 diseaaeH ig commg Hhat duul.
eadache mau be reheued by a ug le able
pirunuöher as severe headache nos
seauive adinistraim 2-3 talylets

Roudeadsinighralhon n general,1he rapidk-


obsotuptim.d dng decd eaae aum.tate

nsavenbus Intramaculba) subeiisncoue


dral- 2.Sag
Jtrawmoalos-lng
ntsayentunsDSug

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Aime aolunistaten.e dngs ar most qwcly


alosokedom eehystomach 2
hepreaenceoo in he atomoch deloy
OsDptim Hence a pölent: dag gien
betoe 'mea 20
AntttrHent daug 2iven a{ter mol
nd pvduce leK
du igdiluteddit ad
ciniom
xnuency dKq adnunstzationr islogical kalt lie
adag8
ad hat i the timereequiteedort blod level
to dsop doon to SO the in'hal_ peok level in he
ain actort ot govercninge reuency dr2
odiistxatiad,
2xt lslogicad ballide a sulphoclia2ineis 4 hout
1gm-ddmg haa to be taken evettyA hout after
tadose 2aro
notcyatentd
Pyehologicallae 0 Physiholgaical8tate a nd com

tecd #he rexporaeo1 dn


n Nerves_armd anxlous pahend stequures ambte
enerta anoesfhetics
Placebo io an inef 8.dhatance, tat _does ns Contain
dmg
Commomly used placeoose are lactose taklefs and
digilkd' watet.
XSllerome SOme cidaen eva Con tölertade relathd
Onge doses a ssenit,belladma, etc
seraace an be aqwred aa a resudt cepeaBed
odnainastsalion coned
2n mornpane,héroin, tocone

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elass
Date
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multounedus adrumeration-2ot moedng


Aoddutiom The combineacHioo
Sum .
uo0
da is uad o someindivudual ettet.
exol 1+1 2
bupaiin tpoaacetamd1eAnalgchei
ynertgimThey
U,
ettect pMduced s greatt
founthe atuthmetickum De
t0o dmugs
4=>2
An codelngt Aspireinmode taom Aualgeha
Antagonsm
A substasté thai gBops tve aatian.
ontet sie ekiecl aand suk kthanee
EXonplt
Aptibictamines dacka AisthminesAy)t
Accomulatisn Amy dug ill _accumulate in
2-bod e ale Aaksapion IS mefto
he tatt eliminaion
0n eliminattd druo ae. aAen oltumulatd
iM he õdy er
&x
ampáuse toMiciky
Polouaedt chvoguneeasile
lanas EAto eetoine, etE tehua
kbeyncho onmd Hypert3engitivihs
Sd iosn chrosy tISim
tatep.Honal
toodrtug ine tdidiual pohtn. teanse
EMamle n sme pat
oapin_haaucae
sOAséagtiaomapemllin:icilis aauie
rti tat Rnhes mHe h.

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clasSMAte
Date
Page

Hpertseneativity 4, ia an advertse eeet Renctid=


TCclag
CctuRg due tochemical reaction tesultig aom-
pme vidus exposurtR, to the substante, 0CCuAig
n
wy in a nall rac kim all pesple
etee Reaeiu he
pooti.cula drg-

Yediatic dose calculatign


NomoamMefhod t is ußed to delertmine he
cotreecpaedia peeliatncmedicatin.dosage
bovaed 0 body Sutace aria
hld dose = Cwld béd BSA in meBet X
Adult des
118
larks Rule
Child dse ol qclild los) y Adulidese

YOs RuleCuk dese-Age.a chid.Chs)xA


-AduHda6
Age. l2
trend rule cld dase -Aae.ocld (Mantia
Alult doK
ISQ
A
so AY-
YoU
XAduutHtgt
Aose t1L2

ATY o
620
eloraloo

0-
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alass
12/2
AsSTGNMENT-04.
HARMICEUTICAL CALCULATION

Deinatian
Metcic Sysiem-Most a he courties,use he meic.
Systemdhich usesméaauringwnit 3uchaameterto,
ams, Kiloyaam,mílliaxan8,cemimelerta
Inpetial ayslem-In Hhe inided 3tales pecple oise the aldert
iperial 3ystem,here things ate meaauted in ee,-
inchesounces poulpds,yaadga
lable metruc length

1 kilometerKm) l600 melernt


1hectometert(hm) l6D metert
1 decámeterr(dam)E10melerei
meterre 1melere i ylii2
1deimelertdrn) Ol60etert
lcendimetestAcm)s 0.0l0metet
1 millimeiereéom)EO00Lmeter
1micrtocmelert(Am)EO.OITN meler
1nanometet mm)OAKCO,GOO,cO1.

quidelineg ore 0tivng aot use aS1 ustem.


*LInt ames and umbal genernaldyate n Loritfeo
1ocapidal letee:excep henldree used a ihe
beginnig a gerndence ort ieoti heaiding
* Poriod is n used jalloxoing 1synabats ceceplat he
Rnd a senence.
apleAmd md Agm

A mpourd u hai is ralio a quaiat ta


wr is indicaled by a älidus C) Sndh_ed Snd h
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lOMoARcPSD|19132033

elAs
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Smb should not he combine spela


Ou fermS in ihe 3ame exprecsan.

aBmnm
Furals a uii names uhen spelled out
have an addeds)Sumb61 kort un hoee
duRe fhe same in giuguuanand plural
exopleSmlliteeg nat ShLL
Dedma mctoo are used nt Common
tm bion exanaple S.25g.m nd# Sagm-

PercentagePreepaaation

The percenlageconceotzahiaoachive
and inactive constiRted in vasious ty pes
phogmaceulitalpaeposationane defmed
tlons by the uP

ferecendoge_oeighdinwalunnelW/y)-
Aexprees the numbere
oms consdituei in1nl sötution.ar
liquid prepacation.

Yerce.ntage dlumen võlume V


express fhe number millime
tera a conetitue n l0D uhon or
lquid pteparcaHon.

L Pecceotagevoeight in ieigbdCiws)
O expees the number a
so cowatituend in lDgm dpreacah.

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lOMoARcPSD|19132033

elassmate
Date
Page

Ohat is allegahion and give dne example


allegation method 2

Ais an arhmelical methad 4saving posblems1ha


nvslves the mirig the salutionore mixtute o
Salids poasessingelete pertcenioge strength

Allegation méthad pablem


n hat pooportion shoud alcshs 9SZ and S0Z
Stnength be mixed to make 0/._alc hal

20/

204 95Z and-257 q SD


4'S ratio

eite the toxmula tor spired caladahonsreezig


pai methodand i NaCl euivalent methodi

socalclate e rumbereapr allon akttlated


cordained in a gienauaztiky olushsl a specikeel

501
Exausple : Houd many pusigallon arte in 3 ine galam

4
P allon SXIS u5
SD

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lOMoARcPSD|19132033

Fage

FreeRing pain method


blood ad dhere
Ihe yreeezing paind
bdy{uid
bd . is-.s2heprepaaah

addihxes. mu3t kave


ainngdaugand
2ii
eual deeiung point

Teeczig paint raethol


Teezing peint kddfhid
li reezig poi a dug sål.al
Distialart Stoengtä

(veeag poi tonioity adjul

Calculate the ámawd sádium La7,dred


Ao make SK dextanse sdlutton isdtow

0.S2 0,4SS

Sodiumchloide euialend method

Equivaleat method aNaclL


Maluooi Nad iact a the 3ubsor
acioraNaiMslidt slsubshamë.
baioo
tdpoxte
elCaleudade the Xsodiiy chloide equivalentjo
alycercine,o ropelectre+luieolth molecular i
1217acor.

5R
92
8.2.5X 0-01
O82S.2 2EX oli

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