Cell inclusions

By
Dr. Shereen Hamed
Lecturer of Histology & Cell Biology Faculty of
Medicine, Mansoura University
 CELL

Cell
Cytoplasm
membrane

Cell Cell
Cell matrix
organelles inclusion
 Cell inclusions
DEF:
Non living materials in the cytoplasm.

Include:

1.Stored food: includes carbohydrates and lipids.

2.Pigments.

3.Crystals
 Carbohydrates
Stored in the cell as glycogen
granules.
Site: Liver cells.
Muscle fibers.
 Lipids
Stored as:
• Small droplets in liver cells.

• Large globules in connective

tissue fat cell.
 Pigments

Colored substances.

•Can be seen in the cell

without staining.
 Exogenous Endogenous
M
Minerals Melanin

c
Lipo hrome pigments: e.g. f
Lipo uscin pigment
carotene

Dust Haemoglobin

attoo marks
T Haemoglobin derivatives e.g.
bilirubin
 Dust

Small dust particles are

inhaled enter the respiratory
system.

•Phagocytozed by
macrophages in the lung
black pigmentation.
 Lipofuscin pigment
Golden brown in color.
•Present in the cardiac muscle
fibers, nerve cells and
hepatocytes.
•Regarded as wear and tear
pigment
•Increase with age.
 References
• Principles of histology, (student book of
Histology & Cell Biology Department, faculty
of medicine, Mansoura university)

• Basic Histology, text book of histology & cell

biology

• Prof.dr. Nesreen Moustafa’s short notes