Jeimarie Casey R.

Pedraya
12 – STEM San Ezekiel Moreno

Mitochondrial Diseases

Disease Cause Effect

Mitochondrial Myopathy – Genetic mutations cause Muscle weakness or

is a group of this disease. Genes code exercise intolerance, heart

neuromuscular diseases for proteins, and the genes failure or rhythm

caused by mitochondrial involved in mitochondrial disturbances, dementia,

dysfunction disease normally code for movement disorders,

proteins that function inside stroke-like episodes,

mitochondria. deafness, blindness,

droopy eyelids, limited

mobility of the eyes,

vomiting, and seizures are

all symptoms of

mitochondrial myopathies.

Alpers Disease or Alpers syndrome is a This disease's symptoms

Syndrome - is a genetic disease caused by include increased muscle

neurodevelopmental one or more genes not tone with exaggerated

syndrome characterized by working properly or by reflexes (spasticity),

Jeimarie Casey R. Pedraya
12 – STEM San Ezekiel Moreno

mitochondrial DNA genetic changes in the seizures, and cognitive

depletion. POLG gene. impairment (dementia).

Mitochondrial Diabetes - This is caused by insulin- Mitochondrial diabetes

Diabetes can be a possible producing cells in the symptoms are similar to

cause of a mitochondrial pancreas malfunctioning those of type 1 and type 2

disorder if the cells in the and/or the emergence of diabetes. Increased and

pancreas responsible for insulin resistance as part of significant thirst, increased

insulin production are a mitochondrial disorder. urination, increased

affected. appetite but weight loss

rather than gain,

dehydration, blurred vision,

nausea and vomiting,

irritability, and mood

changes are examples.