NAME – HARDIK ROY

CLASS – XIth A
ROLL NO. – 4
SUBJECT – CHEMISTRY
PROJECT ON:-
To analyse the given samples of commercial antacids by
determining the amount of hydrochloric acid they can
neutralize.
ACADEMIC YEAR– 2022-2023
This is certified that Master Hardik Roy of class
XIth section ‘A’ roll no. 4 is a bonafied student of
Rahul International School.

This is certified to be the bonafide work of the

student in the Chemistry subject during the
academic year 2022 - 2023. He worked hard to
complete this project and this project is a result of
his great efforts and attention.

Date: 15/01/2023
Sign of examiner

Sign of principal Sign of subject teacher

 INDEX
Sr no Content
1 Introduction
2 Aim
3 Requirements
4 Procedure
5 Observation table
6 Result
 ACKNOWLEGEMENT

In the accomplishment of this project

successfully, many people have best owned upon
me their blessings and the heart pledged support,
this time we utilizing to thank all the people who
have been concerned with this project. I would
like to thank my Chemistry teacher Miss Puja
Sankhe who is valuable guidance has been the
ones that helped me patch this project and make it
full proof success, her suggestions and
instructions has served as the major contribution
towards the completion of project. Then I would
like to thank our parents, friends and classmates
who have helped me with their valuable
suggestions and guidance has been helpful in
various phases of the project.
 INTRODUCTION
Digestion in the stomach results from the action of
gastric fluid, which includes secretions of digestive
enzymes, mucous, and hydrochloric acid. The acidic
environment of the stomach makes it possible for
inactive forms of digestive enzymes to be converted
into active forms (i.e. pepsinogen into pepsin), and acid
is also needed to dissolve minerals and kill bacteria
that may enter the stomach along with food. However,
excessive acid production (hyperacidity) results in the
unpleasant symptoms of heartburn and may contribute
to ulcer formation in the stomach lining. Antacids are
weak bases (most commonly bicarbonates, hydroxides,
and carbonates) that neutralize excess stomach acid
and thus alleviate symptoms of heartburn. The general
neutralization reaction is:
Antacid (weak base) + HCl (stomach acid) —> salts +
H20 + C02
The hydrochloric acid solution used in this experiment
(0.1 M) approximates the acid conditions of the human
stomach, which is typically 0.4 to 0.5% HQ by mass (pH
~ 1).Antacids help people who have or get heartburn.
The following information will help people understand
how stomach acid works and what antacid will help
those most.
 INVESTIGATORY EXPERIMENT
Aim: To analyse the given samples of commercial antacids
by determining the amount of hydrochloric acid they can
neutralize.
REQUIREMENTS: Burettes, pipettes, titration flasks,
measuring flasks, beakers, weight box, fractional weights,
sodium hydroxide, sodium carbonate, hydrochloric acid,
phenolphthalein.
PROCEDURE:
1. Prepare 1 litre of approximately HCl solution by diluting
10 ml of the concentrated acid for one litre.
2. Similarly, make 1 litre of approximately NaOH solution
by dissolving4.0g of NaOH to prepare one litre of solution.
3. Prepare Na2CO3 solution by weighing exactly 1.325 g of
anhydrous sodium carbonate and then dissolving it in water
to prepare exactly 0.25 litres (250 ml) of solution.
4. Standardize the HCl solution by titrating it against the
standard Na2CO3 solution using methyl orange as
indicator.
5. Similarly, standardize NaOH solution by titrating it
against standardized HCl solution using phenolphthalein as
indicator.
6. Powder the various samples of antacid tablets and weigh
1.0 g of each.
7. Add a specific volume of standardized HCl to each of
the weighed sample is taken in conical flasks. The acid
should be in slight excess, so that it can neutralize all the
alkaline component of the tablet.
8. Add 2 drops of phenolphthalein and warm the flask till
most of powder dissolves. Filter off the insoluble material.
9. Titrate this solution against the standardized NaOH
solution, till a permanent pinkish tinge is obtained. Repeat
this experiment with different antacids.
OBSERVATIONS AND CALCULATIONS:

1. Standardization of HCl solution:

Volume of Na2CO3 solution taken = 20.0 ml

S.NO. INITIAL FINAL VOL. OF

BURETTE BURETTE ACID USED
READING READING
1. 0 15 15.0 ml
2. 15 30 15.0 ml
3. 30 45.1 15.1 ml
4. 0 15 15.0 ml
5. 15 30 15.0 ml

Concordant volume = 15.0 ml

Applying normality equation,
N1V1 = N2V2
N1 * 15.0 = 1 * 20
Normality of HCl, N1 = 0.133 N
2. Standardization of NaOH solution:
Volume of the given NaOH solution taken = 20.0 ml

S.NO. INITIAL FINAL VOL. OF

BURETTE BURETTE ACID USED
READING READING
1. 0 26.5 26.5 ml
2. 0 26.8 26.8 ml
3. 0 26.6 26.6 ml
4. 0 26.6 26.6 ml
5. 0 26.6 26.6 ml

Concordant volume = 26.6 ml

Applying normality equation,
N1V1 = N2V2
0.133 * 26.6 = 2 * 20
Normality of NaOH, 2 = 0.176 N
3. Analysis of antacid tablet :

Weight of antacid tablet powder = 1.0 g

Volume of HCl solution added = 20.0 ml

ANTACID VOL. OF NaOH VOL. OF HCl

USED TO USED TO
NEUTRALISE NEUTRALISE
HCl 1.0gm ANTACID
Gelusil 12.1 ml 12.0 ml
Digene 16.0 ml 16.2 ml
Aludrose 19.3 ml 18.9 ml
Logas 24.3 ml 24.4 ml
Ranitidine 21.4 ml 21.7 ml
Ocid 20 22.7 ml 21.9 ml
RESULT:
The antacid which has maximum volume of HCl is used
for neutralizing i.e. OCID 20 is more effective.

BIBLIOGRAPHY
I HAVE TAKEN HELP FROM:
INTERNET
CHEMISTRY PRACTICAL FILE
CHEMISTRY BOOK
MY CLASSMATES
MY SIBLINGS
CHEMISTRY LAB (for observations and tests..)