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* :Treatment of infanitale spasm

The same as myoclonic treatment

*Treatment of depression
Tricyclic anti-depressant (Impiramine is first choice -1
for major depression)
selective serotonin reuptake inhibitors :fluoxetine-2
Monoamine oxidase inhibitors : Ipronazide second or -3
third choice
. Atypical anti-depressant : Bupropiron-4

Treatment of hyperglycemia*
. Type1-insulin replacement

Type2-oral hypoglycemic and\or insulin but only

in conjunction with program of diet modification
and exercise

*: Oral hypoglycemic
sulfonylureas-1

Biguanides-metformi-2

Alpha-glucosidase inhibitors –acarbose-3

Thiazolidinediones –Troglitazone-4
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*:Treatment of Tardive dys kinesia

minimize the dose of anti-psychotic -1
drugs or give frequent drug holidays
give dopamine depleting agents -2
(reserpine)
if patient on antipsychotic -3
+anticholinergic drug combination ,stop
anticholinergic drugs
give dopamine release inhibitory -4
agents(diazepam)
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:Ketoecnazole is metabolic inhibitor-9

Because it causes microsomal enzyme inhibitor-
cytochrome oxidize enzyme(decrease dismutase
enzyme)

Ethambuttol is combined with(INH) -10

isonicotinic acid hydrazide in treatment
:of tuberculosis
Because ethambutol increase penetration of INH

prolonged testosterone therapy -11

:produce gynocomastia
Because part of testosterone change to estrogen in the
body

:clomiphene citrate induce ovulation-12

Because it estrogen receptor antagonist

Entacapone is added to sinemet -13

:under the name stalevo
Because entacapone is COMT inhibitor so enhance the
affect of carbidopa (sinemet)by inhibiting decarboxylase
in periphery . Stalevo (entacapon+carbidopa+L .dopa)
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Nandodaron is used in treatment of -14

:aplstic anemia
Because it has anabolic effect of testosterone on bone
. marrow increase synthesis of RBC

Q)What are factors that should be

?followed for choosing proper antibiotics
Efficacy: concentration-penetration-spectrum-1
Safty : side effect-concentration-2
Suitability: rout of administration-3
:Cost-4