C.U.

SHAH MEDICAL COLLEGE

Department of Pharmacology
Preliminary Exam- November - 2015
Batch N-Major
PAPER-1
Time: 2 hours Total Marks: 40
Instructions: Write both the sections in separate answer sheets.

SECTION – I [20]
Q.1 Answer ANY ONE of the following. 8
(1) Classify cholinesterase inhibitors. Mention their therapeutic indications.
(2) Classify anti psychotic agents. Mention their pharmacological actions, therapeutic uses, and adverse
effects.

Q.2 Write in short about ANY TWO of the following. 6

(1) Transmembrane JAK-STAT binding receptors.
(2) Enzyme inhibition as a mechanism of drug action.
(3) Medical management of tonic-clonic status epilepticus.

Q.3 Answer in brief: 6

(1) Mention atleast two limitations of oral route of administration.
(2) Explain the ‘cross over’ design in clinical trials.
(3) Enlist the drugs used for Preanaesthetic medications.
(4) Enlist the types of clinical studies.
(5) Name the antidote for acute benzodiazepine overdose.
(6) Mention the advantage of S(-)Atenolol over Atenolol.

SECTION – II [20]

Q.4 Answer ANY ONE of the following. 8

(1) Classify vasodilators. Mention their clinical utility.
(2) Classify Ca. Ch. Blockers . Mention their salient aspects in Pharmacology.

Q.5 Write in short about ANY TWO of the following. 6

(1) Parenteral iron therapy.
(2) Differentiate Centrally acting Vs Peripherally acting muscle relaxants. (Minimum 4 points)
(3) Adverse effects & contraindications of Heparin .

Q.6 Answer in brief: 6

(1) Enlist atleast two uses of Mannitol.
(2) Explain ‘Fondaparinoux’.
(3) Name any two vasopressin analogues.
(4) Explain the role of Vit B12 in any one metabolic functions of our body.
(5) Name any two direct thrombin inhibitors.
(6) Mention the usefulness of Prasugrel in STEMI.

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 C.U.SHAH MEDICAL COLLEGE
Department of Pharmacology
Preliminary Exam- November - 2015
Batch N-Major
PAPER-2
Time: 2 hours Total Marks: 40
Instructions: Write both the sections in separate answer sheets.

SECTION – I [20]
Q.1 Answer ANY ONE of the following. 8
(1) Classify broad spectrum antibiotics & mention the salient aspects of any one of them.
(2) Classify ‘Corticosteroids’. Mention the therapeutic uses, adverse effects & contraindications of
‘Glucocorticoids’.

Q.2 Write in short about ANY TWO of the following. 6

(1) Third generation Cephalosporins.
(2) Drug therapy for acute uncomplicated cystitis.
(3) Drug resistance.

Q.3 Answer in brief: 6

(1) Name the drug of choice for post partum hemorrhage for a hypertensive lady.
(2) Imipenem + cilastatin is preferred to be given in combination.- Explain.
(3) Some of the second generation anti histaminic should not be given with ketoconazole.-EXPLAIN.
(4) Name any one ectoperasitic infection and name the most efficacious broad spectrum drug of choice
for them.
(5) Write the mechanism of action of ‘azole antifungals.’
(6) Mention the drugs used for prophylaxis of migraine.(at least two from different classes)

SECTION – II [20]

Q.4 Answer ANY ONE of the following. 8

(1) Classify antitubercular drugs. Mention the latest WHO categorization. Write the management of
category 1 patients.
(2) Classify the drugs used for ‘Amoebiasis’. Mention the important aspects of ‘Metronidazole’.

Q.5 Write in short about ANY TWO of the following. 6

(1) Pharmacological basis of oseltamivir in Swine flu.
(2) Artimisinin based combination therapy (ACT).
(3) Medical management of dehydration due to diarrhea.

Q.6 Answer in brief: 6

(1) Name at least two uses of Ivermectin.
(2) Enlist the therapeutic uses of lamivudine.
(3) Antacids should be avoided in peptic ulcer disease. – EXPLAIN.
(4) Name any two drugs useful for Neurocysticercosis.
(5) Name anyone chelating agent with its clinical use.
(6) Mention the advantage of Cresol over Phenol with its use.

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