Sheet1

No Preservatives Classification Optimum pH Stability pH Uses LD 50 Notes

If ingested
orally,
cetrimide and
other
quaternary
LD50 (mouse,
ammonium
oral):
Quartenary ophthalmic, compounds
Benzalkonium 150 mg/kg
2 Ammonium 4 – 10 6.5 – 7.5 nasal, otic, can cause
Chloride LD50 (rat,
Compound SVP, topical nausea,
oral):
vomiting,
300 mg/kg
muscle
paralysis, CNS
depression,
and
hypotension
If ingested
orally,
cetrimide and
other
quaternary
LD50 (mouse,
ammonium
oral):
Quartenary injections, compounds
Benzethonium 338 mg/kg
3 Ammonium 4 – 10 5.0 – 6.5 ophthalmic, can cause
Chloride LD50 (rat,
Compound otic nausea,
oral):
vomiting,
368 mg/kg
muscle
paralysis, CNS
depression,
and
hypotension
If ingested
orally,
cetrimide and
other
quaternary
LD50 (mouse,
ammonium
oral):
Quartenary compounds
ophthalmic, 106 mg/kg
6 Cetrimide Ammonium 7-9 No data can cause
topical LD50 (rat,
Compound nausea,
oral):
vomiting,
410 mg/kg
muscle
paralysis, CNS
depression,
and
hypotension

Page 1