NAME OF MECHANISM OF DOSAGE INDICATIONS CONTRAINDICATIONS SIDE EFFECTS NURSING

DRUG ACTION RESPONSIBILITIES

Generic name: Salmeterol is a long Dosage: For maintenance treatment  Hypersensitivity to the Common: Before administration:
Fluticasone acting beta-2 250/50 (250 mcg of asthma active substances or to Hoarseness 1. Advise patient to inhale
propionate, adrenergic receptor of fluticasone any of the excipients: Headache the dose at the same time
Salmeterol agonist that binds to propionate and 50 Lactose monohydrate Soreness of the each day to obtain the best
xinafoate both the active and mcg of (which contains milk throat or tongue effect
exo sites of the beta- salmeterol) per proteins). Muscle cramps 2. Keep in patient’s mind
(Seretide)
2 adrenergic breath Increase in heart that this accuhaler will not
receptor. Salmeterol rate give relief in an acute
Brand name:
has a longer Frequency: attack. He will need to use
Seretide duration of action other medications for acute
250/50 (250 mcg Serious:
Accuhaler DPI than other beta-2 of fluticasone Allergic reactions relief, such as a ventolin.
agonists like propionate and 50 Rounded face 3. Remind patient to do not
Classification: salbutamol.Patients mcg of Loss of bone density take medicine after the
Corticosteroids should be counselled salmeterol) per Cataract, glaucoma expiry date (EXP) printed
regarding the risks breath BID on the pack or if the
of long acting beta packaging is torn or shows
agonist (LABA) Route: signs of tampering.
monotherapy, Oral Inhalation 4. Check whether there are
hypokalemia, possible drug interactions
hypoglycemia, and that may interfere with
not to take this drug drug’s effects.
with another LABA. 5. Tell patient that the
medication does not cure
Beta-2 adrenoceptor asthma but alleviate the
stimulation causes symptoms so he must
relaxation of continue taking his
bronchial smooth medicine
muscle, 6. Remind patient that if he
bronchodilation, and missed the dose, and it is
increased airflow. almost time for next dose,
skip the dose missed and
Salmeterol is use the next dose when he
hypothesized to bind is meant to. Otherwise, use
to 2 sites on the it as soon as you
beta-2 remember, then go back to
adrenoceptor.1 The using it as he would
saligenin moiety normally. Do not use a
binds to the active double dose to make up for
site of the beta-2 the dose that missed.
adrenoceptor.1 The 7. Advise that he must tell
hydrophilic tail of physicians if he is about to
salmeterol binds to take new medicines.
leucine residues in
the exo-site of the During administration:
beta-2 adrenoceptor 1. Remind patient to
almost irreversibly, follow all directions
allowing salmeterol given to him by
to persist in the doctors or pharmacist
active site, which is carefully.
responsible for its 2. Follow the same dose
long duration of each use
action. 3. Educate that Seretide
should be inhaled to
Salmeterol protects the lungs and must
against symptoms, only be breathed
fluticasone through mouth
propionate improves
lung function and After administration:
prevents 1. Tell patient that after
exacerbations of the using Seretide
condition. accuhaler, he should
rinse his mouth with
water and spit it out.
2. Report changes to the
doctor, including side
effects
3. Advise that the
medication should be
hygienically protected
4. The inhaler must be
clean atleast once a
week
5. Warn the patient that if
he took too much dose,
call physician
immediately.
6. Educate patient to keep
SERETIDE in a dry
place where the
temperature stays
below 30°C, away
from direct heat or
sunlight.
7. Do not store
SERETIDE or any
other medicine in the
bathroom or near a
sink. Do not leave it on
a window sill or in the
car. Heat and dampness
can destroy some
medicines.
 NAME OF MECHANISM OF DOSAGE INDICATIONS CONTRAINDICATIONS SIDE EFFECTS NURSING
DRUG ACTION RESPONSIBILITIES
Generic name: Activation of beta2- Dosage: For the treatment or  History of Common: Before administration:
Albuterol adrenergic receptors 180 mcg for 2 prevention of hypersensitivity to any Nervousness, 1. Instruct patients to
sulfate on airway smooth inhalations bronchospasm in patients of the ingredients of shaking (tremor), prime VENTOLIN
inhalation muscle leads to the aged 4 years and older with Ventolin headache, HFA before using for
aerosol activation of adenyl Frequency: reversible obstructive  Patients with serious mouth/throat the first time, when the
cyclase and to an 180 mcg for 2 airway disease. heart illness dryness or inhaler has not been
Brand name: increase in the inhalations q6 irritation, changes used for more than 2
intracellular in taste, cough, weeks, or when the
Ventolin HFA
concentration of Route: nausea or dizziness, inhaler has been
cyclic-3',5'- Oral Inhalation raise in blood dropped. To prime
Classification:
adenosine pressure VENTOLIN HFA,
Bronchodilators/
monophosphate release 4 sprays into
Beta2 Agonists
(cyclic AMP). This Serious: the air away from the
increase of cyclic fast/pounding face, shaking well
AMP leads to the heartbeat before each spray.
activation of protein chest pain, 2. Inform patients that
kinase A, which irregular heartbeat, VENTOLIN HFA can
inhibits the rapid breathing, produce paradoxical
phosphorylation of confusion bronchospasm. Instruct
myosin and lowers them to discontinue
intracellular ionic VENTOLIN HFA if
calcium paradoxical
concentrations, bronchospasm occurs.
resulting in 3. Advise patients that
relaxation. Albuterol while they are using
relaxes the smooth VENTOLIN HFA,
muscles of all other inhaled drugs and
airways, from the asthma medications
trachea to the should be taken only as
terminal directed by the
bronchioles. physician.
Albuterol acts as a 4. To prevent exercise-
functional induced bronchospasm,
antagonist to relax use this medicine 15 to
the airway 30 minutes before you
irrespective of the exercise. The effects of
spasmogen Ventolin should last
involved, thus about 4 to 6 hours.
protecting against all 5. Ventolin HFA must be
bronchoconstrictor shaken well before
challenges. each use.
Increased cyclic 6. Check for possible
AMP concentrations drug instructions
are also associated
with the inhibition During administration:
of release of 1. Use Ventolin
mediators from mast exactly as
cells in the airway. prescribed by your
doctor. Follow all
directions on your
prescription label
and read all
medication guides.
2. Ventolin should be
used only when
needed. Use the
missed dose as
soon as you
remember. Skip the
missed dose if it is
almost time for
your next
scheduled dose. Do
not use extra
medicine to make
up the missed dose.
3. Advise that the
inhalation should
be of use of mouth.
 4. Observe how
patient intakes the
medicine

After administration:
1. To ensure proper
dosing and to prevent
actuator orifice
blockage, instruct
patients to wash the
actuator with warm
water and let it air-dry
completely at least
once a week. Inform
patients that detailed
cleaning instructions
are included in the
Patient Information
leaflet.
2. Tell patient that this
drug may make you
dizzy. Do not drive,
use machinery, or do
anything that needs
alertness until you can
do it safely. Limit
alcoholic beverages.
3. Store at room
temperature away from
moisture, heat, or cold
temperatures.
4. Store Ventolin HFA
with the mouthpiece
down.
5. Keep the inhaler
canister away from
 open flame or high
heat. The canister may
explode if it gets too
hot. Do not puncture or
burn an empty inhaler
canister.
6. Note for signs of
overdosage
7. Rinse with water if this
medicine gets in your
eyes.
8. Advise patients to
report signs of side
effects