Mechanism of Action: Prevents the transport of H ions into the gastric lumen by binding to gastric

parietal cells, ↓ gastric acid production.

Indication: Treat certain stomach and esophagus problems by decreasing the amount of acid that
the stomach makes.

Contraindication: Hypersensitivity to the drug and reactions like anaphylactic shock

Adverse Effect: Constipation, diarrhea, nausea, vomiting, heartburn, stomach pain, headache, unusual or
unpleasant taste in the mouth

 Check and verify doctor’s order.

 Assess and monitor vital signs before and after administration.
 Assess for history of hypersensitivity to the drug.
 Educate patient and family about the medication and its side effects.
 Follow the rights of medication. (Right Patient, Drug, Dose, Route, Time)
 Assess and monitor for the therapeutic effect of the medication.
 Instruct patient to report black tarry stool
 Assess for possible contraindications and cautions: history of allergy to a proton pump inhibitor
to reduce the risk of hypersensitivity reaction 
 Inspect and palpate the abdomen to determine potential underlying medical conditions; assess
for changes in bowel elimination and GI upset to identify possible adverse effects.