Jawood, Kedren Kent G.

BSN 4B/Sherwin G. Maputol, RN, MAN

Drug Study

Date and Drug Name/ Classifications/ Indications/ Adverse Nursing Actions

Time Dosage/Frequency/ Mechanism of Contraindications Reaction
Ordered Route/Timing Action

March 30, Generic: Mannitol - Osmotic Diuretic - To reduce CNS: - Monitor I.V. site
2023 Brand: Osmitrol intracranial dizziness, carefully to avoid
- Increases pressure headache extravasation and tissue
100 mL Q4 IV osmotic pressure necrosis
of plasma in Contraindicated CV: chest
glomerular filtrate, with: pain, - Insert indwelling
inhibiting tubular - Anuria hypotension, urinary catheter as
reabsorption of - Progressive heart hypertension, ordered to monitor urine
water and failure tachycardia output
electrolytes - Pulmonary
(including sodium congestion EENT: - Monitor renal function
and potassium). - Severe blurred tests, urinary output,
These actions pulmonary vision, rhinitis fluid balance, central
enhance water congestion venous pressure, and
flow from various - Severe GI: nausea, electrolyte levels
tissues and dehydration vomiting,
ultimately diarrhea, dry - Watch for excessive
decrease mouth fluid loss and signs and
intracranial and symptoms of
intraocular GU: polyuria, hypovolemia and
pressures; serum urinary dehydration
sodium level rises retention
while potassium - Assess for evidence of
and blood urea Metabolic: circulatory overload,
levels fall dehydration, including pulmonary
water edema, water
intoxication,
Jawood, Kedren Kent G.
BSN 4B/Sherwin G. Maputol, RN, MAN
hypernatremi intoxication, and heart
a, failure
hyponatremia
, - Teach patient about
hypovolemia, importance of
hypokalemia, monitoring exact urinary
hyperkalemia output
, metabolic
acidosis - Advise patient to report
pain at infusion site as
Respiratory: well as adverse
pulmonary reactions, such as
congestion increased shortness of
breath or pain in back,
Skin: rash, legs, or chest
urticaria
- Tell patient drug may
Other: chills, cause thirst or dry
fever, thirst, mouth
edema,
extravasation - As appropriate, review
with edema all other significant and
and tissue life-threatening adverse
necrosis reactions and
interactions, especially
those related to the
drugs and tests
mentioned above
Jawood, Kedren Kent G.
BSN 4B/Sherwin G. Maputol, RN, MAN

Drug Study

Date and Drug Name/ Classifications Indications/ Adverse Nursing Actions

Time Dosage/Frequency/ Mechanism of Contraindications Reaction
Ordered Route/Timing Action

March 30, Generic: Citicoline - Central - Cerebrovascular Fleeting and - Instruct patient to
2023 Brand: Somazine stimulant,
Nootropic agent diseases, e.g. from discrete take the medication
ischemia due to hypotension as prescribed
1 gram 1 tab BID - Citicoline stroke, where effect, increased
consumption
Citicoline accelerates parasympathetic - Teach the patient
promotes brain
metabolism by the recovery of effects, itching that citicoline may be
restoring consciousness and or hives, taken with or without
phospholipid overcoming motor swelling in face food
content in the
brain and deficit or hands, chest
regulation of tightness, - Monitor for adverse
neuronal Contraindicated with: tingling in mouth effects; instruct
membrane
excitability. It also - Cognitive disorders and throat, patient to report
influences the of diverse etiology headache, immediately if he/she
mitochondria or nausea, develops chest
energy factories
- Citicoline improves diarrhea, blurred tightness, tingling in
of the brain cells
and found to scores on cognitive vision mouth and throat,
improve memory evaluation scales and headache, diarrhea
function
slowed the and blurring of vision
progression
of Alzheimer’s
Jawood, Kedren Kent G.
BSN 4B/Sherwin G. Maputol, RN, MAN

Disease. Beneficial
neuroendocrine,
neuroimmunodulatory,
and
neurophysiological
effects have been
described
Jawood, Kedren Kent G.
BSN 4B/Sherwin G. Maputol, RN, MAN

Drug Study

Date and Drug Name/ Classifications/ Indications/ Adverse Reaction Nursing Actions
Time Dosage/Freq- Mechanism of Action Contraindicatio
Ordered uency/ ns
Route/Timing

March 30, Generic: - HMG-CoA reductase - Adjunct to diet CNS: headache, - Monitor patient for
2023 Atorvastatin inhibitor, lipid-lowering for controlling malaise, signs and symptoms of
Brand: Lipitor agent LDL, total paresthesia, allergic response
cholesterol, drowsiness,
80 mg 1 tab - Inhibits HMG-CoA apo-lipoprotein syncope, - Evaluate for muscle
OD reductase, which B, and weakness weakness
catalyzes first step in triglyceride
cholesterol synthesis; levels and to CV: hypotension, - Monitor liver function
this action reduces increase HDL palpitations, test results and blood
concentrations of levels, adjunct vasodilation, lipid levels.
serum cholesterol and to diet to reduce arrhythmias
low-density elevated - Tell patient he may
lipoproteins (LDLs), triglyceride EENT: dry eyes, take drug with or without
linked to increased risk levels hearing loss, food
of coronary artery epistaxis
disease (CAD). Also - Prevention of - Advise patient to
moderately increases cardiovascular GI: nausea, immediately report
concentration of high- disease in vomiting, diarrhea, allergic response
density lipoproteins patients constipation
(HDLs), associated - As appropriate, review
with decreased risk of - Prevention of GU: hematuria, all other significant and
CAD stroke and dysuria, urinary life-threatening adverse
myocardial frequency, urinary reactions and
infarction in retention interactions, especially
patients with those related to the
Jawood, Kedren Kent G.
BSN 4B/Sherwin G. Maputol, RN, MAN
type 2 diabetes Hematologic: drugs, tests, foods, and
who have anemia herbs mentioned above.
multiple risk
factors for CHD Hepatic: jaundice

Contraindicated Metabolic:
with: hyperglycemia,
- hypoglycemia
Hypersensitivity
to drug or its Musculoskeletal:
components joint and back pain,
leg cramps, muscle
- Active hepatic pain, neck rigidity
disease or
unexplained, Respiratory:
persistent dyspnea
serum
transaminase Skin: alopecia,
elevations eczema, dry skin,
rash
- Pregnancy or
breastfeeding Other: taste loss,
fever, facial
paralysis, facial or
generalized
edema, flulike
symptoms, appetite
changes, weight
gain, allergic
reaction
Jawood, Kedren Kent G.
BSN 4B/Sherwin G. Maputol, RN, MAN

Drug Study

Date and Drug Name/ Classifications/ Indications/ Adverse Nursing Actions

Time Dosage/Frequency/ Mechanism of Contraindications Reaction
Ordered Route/Timing Action

March 30, Generic: Aspirin - Nonsteroidal anti- - Mild pain or fever EENT: - Watch for signs and
2023 Brand: Aspilet EC inflammatory drug hearing loss, symptoms of
(NSAID), - Mild to moderate tinnitus hypersensitivity and
1 tab OD nonopioid pain caused by other adverse reactions,
analgesic, inflammation GI: nausea, especially bleeding
antipyretic, vomiting, tendency.
antiplatelet drug - To reduce the abdominal
risk of transient pain, - Stay alert for signs and
- Reduces pain ischemic attacks heartburn, symptoms of acute
and inflammation (TIAs) or anorexia, GI toxicity
by inhibiting cerebrovascular bleeding
prostaglandin accident in men - Monitor elderly
production. Fever with a history of Hematologic: patients carefully
reduction TIAs caused by thrombocytop because they’re at
mechanism emboli enia, greater risk for salicylate
unknown; may be hemolytic toxicity With prolonged
linked to decrease - To reduce the anemia, therapy, frequently
in endogenous risk of myocardial leukopenia, assess hemoglobin,
pyrogens in infarction (MI) in hematocrit, International
hypothalamus patients with a Hepatic: Normalized Ratio, and
resulting from history of MI or hepatotoxicity kidney function test
prostaglandin unstable angina results.
inhibition. Exerts Metabolic:
antiplatelet effect hyponatremia - Check salicylate blood
by inhibiting , levels frequently
synthesis of
Jawood, Kedren Kent G.
BSN 4B/Sherwin G. Maputol, RN, MAN
prostacyclin and hypokalemia, - Evaluate patient for
thromboxane A2. hypoglycemia signs and symptoms of
ototoxicity
Respiratory:
wheezing, - Caution patient to
hyperpnea, avoid activities that may
pulmonary cause injury. Advise him
edema to use soft toothbrush
and electric razor to
Skin: rash, avoid gum and skin
urticaria, injury.
bruising,
angioedema - Tell patient not to take
other over-the-counter
Other: preparations containing
hypersensitivi aspirin
ty reactions,
salicylism or - As appropriate, review
acute toxicity all other significant and
life-threatening adverse
reactions and
interactions, especially
those related to the
drugs, tests, foods,
herbs, and behaviors
mentioned above
Jawood, Kedren Kent G.
BSN 4B/Sherwin G. Maputol, RN, MAN

Drug Study

Date and Drug Name/ Classifications/ Indications/ Adverse Nursing Actions

Time Dosage/Frequency/ Mechanism of Contraindications Reaction
Ordered Route/Timing Action

March 30, Generic: Betahistine - Antiemetic, - Vertigo - Urticaria, - Advise patient that this
2023 Dihydrochloride Antivertigo
Brand: Serc - Meniere’s pruritus, mild drug should be taken
- The mechanism Disease gastric with food.
16 mg 1 tab TID of action of - Tinnitus complaints,
betahistine is not
- Sensorineural false - Advise significant
known. Betahistine
have weak deafness heartbeat, others to support
H1 receptor insomnia patient’s ambulation.
agonistic and Contraindicated
considerable with:
H3 antagonistic - Previous - Teach
properties in the hypersensitive patient/significant others
central nervous reaction to the
to protect medication
system and drug components
autonomic nervous from moisture
system. -
Betahistine also Pheochromocytom - Teach
have a dose a, bronchial
asthma, peptic patient/significant others
dependent
inhibiting effect on ulcer, pregnancy to swallow tablet whole
spike generation of and lactation. with one full glass of
neurons in lateral
water
and medial
vestibular nuclei.
The importance of
Jawood, Kedren Kent G.
BSN 4B/Sherwin G. Maputol, RN, MAN
this observation in - Advise
the action against
Meniere’s patient/significant others
syndrome or to never take a double
vestibular vertigo, dose if missed to take
however, remains
one medication. If
unclear.
missed one, take
medication immediately.