Republic of the Philippines

CAMARINES SUR POLYTECHNIC COLLEGES

Nabua, Camarines Sur
COLLEGE OF HEALTH SCIENCES

DRUG STUDY

DRUG NAME MECHANISM OF INDICATION CONTRAINDICATIONS ADVERSE REACTION NURSING

ACTION CONSIDERATIONS
Generic Name: Inhibits sodium and  For the treatment  Furosemide is Side effects: (by  If oliguria or azotemia
Furosemide
chloride reabsorption of peripheral contraindicated in system) develops or increases,
Brand Name: at the proximal edema or edema anuria. Although, CNS: headaches, dizziness. drug may need to be
Lasix
and distal tubules associated with it can be used in GU: frequent urination stopped.
Therapeutic
Class: and the ascending heart failure, renal
Antihypertensives loop of Henle. chronic lung insufficiency, any Adverse effects: (by  Monitor fluid intake
Pharmacological disease (CLD), or marked increase system) and output and
Class:
Loop diuretics nephrotic in blood urea CNS: vertigo, headache, electrolyte, BUN, and
syndrome. nitrogen or dizziness, Paresthesia, carbon dioxide levels
Dosage/
Frequency/Route: creatinine, or the weakness, restlessness, frequently.
P.O
 For adjunctive development of fever.
20 mg, 40 mg,
80 mg, 100 mg treatment of oliguria during CV: orthostatic hypotension,  Watch for signs of
I.V edema in patients therapy of thrombophelibitis with I.V hypokalemia, such as
10 mg/mL patients with administration.
with acute or muscle weakness and
chronic renal progressive renal EENT: blurred or yellowed cramps.
failure (renal disease, is an vision, transient deafness,
impairment). indication for tinnitus.  Consult prescriber and
discontinuation of GI: abdominal discomfort dietitian about a high-
 Republic of the Philippines
CAMARINES SUR POLYTECHNIC COLLEGES
Nabua, Camarines Sur
COLLEGE OF HEALTH SCIENCES

DRUG STUDY
treatment. and pain, diarrhea,
 For the treatment anorexia, nausea, vomiting,
of hypertension.  Contraindicated in constipation, pancreatitis.
patients in hepatic GU: azotemia, nocturia,
coma or in states Polyuria, frequent urination,
of severe oliguria.
electrolyte Hematologic:
depletion until the agranulocytosis, aplastic
condition is anemia, leukopenia,
improve d or thrombocytopenia, anemia.
corrected and in Hepatic: hepatic
patients dysfunction, jaundice,
hypersensitive to increased liver enzyme
this drug. levels.
Metabolic: volume
depletion and dehydration,
asymptomatic
hyperuricemia, impaired
glucose tolerance,
hypokalemia,
potassium diet or
potassium
supplements.
 Monitor glucose level
in diabetic patients.
 Drug may not be well
absorbed orally in
patient with severe HF.
Drug may need to be
given I.V. even of
patient is taking other
oral drugs.
 Monitor uric acid level,
especially in patient
with a history of gout.
 Monitor elderly patient
 Republic of the Philippines
CAMARINES SUR POLYTECHNIC COLLEGES
Nabua, Camarines Sur
COLLEGE OF HEALTH SCIENCES
DRUG STUDY
hypochloremic alkalosis,
hyperglycemia, dilutional
hyponatremia,
hypocalcemia,
hypomagnesemia.
Musculoskeletal: muscle
spasm.
Skin: dermatitis, purpura,
photosensitivity reactions,
transient pain at I.M
injection site, toxic
epidermal necrolysis,
Stevens-Johnson
syndrome, erythema
multiforme,
Other: gout
who are especially
susceptible to
excessive dieresis,
because circulatory
collapse and
thromboembolic
complications are
possible.
 Monitor patient with
severe of urine
retention due to
bladder emptying
disorder..