SBI4U Quiz: Cellular Respiration-Kreb’s Cycle

Name _______________________

Date ________________________

Part A: Knowledge & Understanding Choose the most correct answer for each of the following
multiple choice questions and circle the letter representing your choice.[10 marks]

1. How many NADH molecules are produced in the Citric acid cycle?
a) 2 b) 3 c)4 d) 8

2. Which of the following is both the starting substrate and the end product of the Kreb’s cycle?
a) malate b) acetyl CoA c) pyruvate d) oxaloacetate

3. Which of the following molecules undergoes a decarboxylation?

a) citrate b) alphaketogluterate c) succinate d) fumerate

4. The correct sequence of the major processes in the Citric Acid Cycle is,
a) citrate 🡪 isocitrate 🡪 alphaketogluterate 🡪 succinyl CoA
b) alphaketogluterate 🡪 succinyl CoA🡪 malate 🡪 fumerate
c) succinyl CoA 🡪 fumerate 🡪 malate 🡪 oxaloacetate
d) none of the above

5. Which of the following processes produces molecular CO2?

a) lactate fermentation b) citric acid cycle
c) glycolysis d) electron transport chain

6. The Kreb’s cycle occurs in the,

a) cytosol b) mitochondrial cristae
c) mitochondrial matrix d) outer mitochondrial membrane

7. The number of CO2 molecules produced during the oxidation of two pyruvate molecules to
oxaloacetate is,
a) 0 b) 2 c) 6 d) 4

8. Ultimately, high energy electrons are captured in which of the following energy carriers?
a) FADH2 - b) ATP c) NADH d) both (a) and (c)

9. If conditions are anaerobic, how many ATP molecules can be produced from the Kreb’s cycle?
a) 36 b) 4 c) 2 d) 1

10. FADH2 is produced during the conversion of,

a) isocitrate 🡪 alphaketogluterate b) alphaketogluterate 🡪 succinyl CoA
c) succinyl CoA 🡪 succinate d) succinate 🡪 fumerate

Part B: Communication Questions Answer the following question in complete sentences where
appropriate.
Use the pathway above to answer each of the following questions.

1. State 1 example of a decarboxylation reaction.[1 mark]

a. Oxidative decarboxylation occurs in Krebs' cycle where a molecule of
coenzyme-A reacts with the α-ketoglutarate to form a 4-carbon compound
succinyl- coenzyme A and releasing carbon dioxide and a pair of hydrogen atoms.

2. State 1 example of a reduction reaction.[1 mark]

a. The oxidation of pyruvic acid results in the reduction of NAD+, production of
Ac-S-CoA and a molecule of CO2.

3. State 1 example of a phosphorylation reaction.[1 mark]

a. The reaction releases sufficient energy to form ATP by substrate-level
phosphorylation.

4. How many carbon atoms are in succinic acid (succinate)? [1 mark]

a. 4 carbon atoms are in succinic acid.

5. State the useful end product(s) of the Kreb’s cycle? [3 marks]

a. The end of the Kerb’s cycle is an organic acid found in citrus fruits like lemons
and oranges, known as citric acid.
b. It produces energy, and is stored and transported as ATP.
c. the product od the kerbs cycle drives the electron transport chain.
6. Why is the production of acetyl-CoA considered a control point for the process of cellular
respiration? [2 marks]
a. Acetyl-CoA provides the acetyl group for energy synthesis in the Krebs cycle.
b. Acetyl-CoA end text serves as fuel for the citric acid cycle in the next stage of
cellular respiration.
c. It helps activate the acetyl group, preparing it to undergo the necessary reactions
to enter the citric acid cycle.