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ALTHOUGH :
It joins clauses.
It is generally used at the beginning of the sentence.
When it is used in the middle of the sentence, it expresses an afterthought and is
usually preceded by a comma.
Examples:
(It was raining. We went on a picnic.)
Although it was raining, we went on a picnic.
DESPITE/IN SPITE OF :
It joins nouns, noun phrases, noun clauses and gerunds (V-ing)
It is used at the beginning (followed by a comma) or in the middle of the
sentence.
“In spite of the fact that “ may be used to join clauses.
Examples:
(It was raining. We went on a picnic. We hate rain)
Despite/In spite of the rain, we went on a picnic.
We went on a picnic despite/in spite of the rain.
In spite of hating rain, we went on a picnic.
In spite of the fact that it was raining, we went on a picnic.
We went on a picnic in spite of the fact that it was raining.
BOTH...AND...
It is used to avoid repetition.
It precedes the first of the two ideas it adds or accumulates.
Examples:
(Mary went to the party. Tom went to the party.)
Both Mary and Peter went to the party.
(Alice went to the cinema with her mother. Alice went to the cinema
with her boyfriend.)
Alice went to the cinema with both her mother and her boyfriend.
NEITHER...NOR...
The verb of the sentence is used in the affirmative form.
It is used to avoid repetition.
It precedes the first of the two ideas it adds or accumulates.
Examples:
(Mary didn’t go to the party. Tom didn’t go to the party.)
Neither Mary nor Peter went to the party.
(Alice didn’t wash the clothes. Alice didn’t iron the clothes.)
Alice neither washed nor ironed the clothes.
(Alice didn’t eat the sandwich. Alice didn’t eat the cake.)
Alice ate neither the sandwich nor the cake.
(Alice didn’t go to the cinema with her mother. Alice didn’t go to the
cinema with her boyfriend.)
Alice went to the cinema with neither her mother nor her boyfriend.
NOT (VERB)...OR…EITHER
It is used with the verb in the negative.
It is not so common as “neither...nor...”
Examples:
(Alice didn’t eat the sandwich. Alice didn’t eat the cake.)
Alice didn’t eat either the sandwich or the cake.
EITHER...OR... :
It is used with the verb in the affirmative to choose between two options.
It precedes the first of the two ideas it chooses between.
Examples:
(Alice will go or Peter will go.)
Either Alice or Peter will go.
(Alice will eat the sandwich or she will eat the cake.)
Alice will eat either the sandwich or the cake.
(Alice will go to the cinema with her mother or she will go to the
cinema with her boyfriend.)
Alice will go to the cinema with either her mother or her boyfriend.
Notice that: