Prevalence of Human Papillomavirus in Women from Mexico City

Nombre del artículo, autores, revista, año.

1. ¿Cuál es el nombre del artículo?
Prevalence of Human Papillomavirus in Women from Mexico City

2. ¿Cuál es el nombre de sus autores?

María Guadalupe López Rivera, María Olivia Medel Flores, José D’Artagnan Villalba Magdaleno
and Virginia Sánchez Monroy

3. ¿En qué revista, volumen, tomo y páginas se publicó?

Hindawi Publishing Corporation Infectious Diseases in Obstetrics and Gynecology Volume 2012,
Article ID 384758,4pages

4. ¿En qué año?

En el año 2012

Introducción
1. ¿Cuál es el tema central del artículo?
Cervical cancer, which is the most common cancer among women in Mexico is
caused by oncogenic HPV infection

2. ¿Cuál crees que sea la pregunta experimental del artículo?

Why might the impact of the HPV vaccine vary depending on the geographic
area?

3. ¿Cuál es la hipótesis principal que hacen los autores respecto a la pregunta

experimental?
Some authors have suggested that geographical differences in HPV distribution may
have an impact on the effectiveness of the HPV vaccine in different populations

4. ¿Cuáles son los objetivos principales de los autores con este artículo?
The goal of the present study was to determine the prevalence and distribution of
HPV types in women from Mexico City.

Material y Métodos
1. ¿Qué metodología utilizaron los autores para responder a la pregunta
experimental?
• Study Population.
• Specimen Collection.
• Cytology.
• HPV Detection and Typing.
• Statistical Analysis.
 2. ¿Los autores utilizaron algún tipo de análisis matemático para los datos que
obtuvieron? En caso afirmativo, ¿cuál?
A statistical analysis was done where several risk factors were calculated.

Resultados
1. ¿Qué indican los resultados obtenidos respecto a la pregunta experimental?

HPV incidence was significantly higher among women with a history of more than one sexual
partner or who were current smokers. There were no differences in the frequency of HPV infection
in women who had intercourse younger than 18 years old or those with histories of sexually
transmitted diseases. Of the HPV-positive women, 99% had high-risk HPV genotypes and 1% had
low-risk HPV genotypes.

HPV HR was detected in 43% of women screened in this study:42% (18) were HPV positive, and
14% (16) were HPV positive, which includes those with both infections. Multiple infections with
different viral genotypes were detected in10% of the positive cases. Abnormal cervical cytology
was detected in only 15.3% of HPV-positive women, and normal cytology was found in the other
84.7%.

2. ¿Los resultados se ajustan a la metodología descrita por los autores?

Of course

3. ¿Crees que la metodología utilizada y los resultados obtenidos corresponden

con los objetivos planteados por los autores?
I think they correspond because with the results they obtained they could know the causes and the
genotypes that provide the HPV in women.

Discusión
1. ¿Con estos resultados, la hipótesis de los autores es validada o negada?
It is denied

2. ¿Los autores encontraron problemas metodológicos o en el planteamiento de

la pregunta experimental original?
They found no problems but other results

3. ¿Los autores proponen otros puntos de vista o metodologías para abordar su

pregunta experimental en el futuro?
These results could have important implications for future screening procedures to assist the
prevention of cervical cancer in Mexico.

Conclusión
1. ¿Qué concluyen los autores?
The differences in HPV prevalence and distribution identified in this study have a potential impact
on the effectiveness of HPV vaccinations, which may be investigated in future studies.
Bibliografía
1. Toma una oración o un párrafo y busca su respectiva cita bibliográfica. Busca
esa referencia en la sección "Referencias, literatura citada o bibliografía" del
artículo. Copia y pega la oración o párrafo, y copia y pega la respectiva
referencia.

Similar to previous age-specific studies, both in Mexicoand other regions of the world, we found
two age groupswith higher HPV prevalences, women less than 20 years oldand women 70–76
years old. The younger age group (<20years old) with a higher incidence of HPV infection may
bean indicator of sexual transmission, as it coincides with theinitiation of sexual activity. The older
age group (70–79 yearsold) of HPV-positive women may have been exposed to highrates of HPV
transmission when they were young or mayhave reactivated latent HPV infections by factors
associatedwith older age [14].
• E.Lazcano,R.Herrero,N.Mu n ̃ oz, A. Cruz, K. V. Shah, andP. Alonso, “Epidemiology of HPV
infection among mexicanwomenwithnormalcervicalcytology,”International JournalCancer,
vol. 91, no. 3, pp. 412–420, 2001.