Beta-Lactamase Database (BLAD)

The Beta-Lactamase Database (BLAD) is a web-based

antimicrobial resistance database that provides structural and
Beta-Lactamase Database
phenotypic data on a class of enzymes, beta-lactamase.[1] It hosts (BLAD)
sequences from all classes of metallo and non-metallo beta- Content
lactamases. The resource has approximately 2000 gene sequences
Description The Beta-
and compiles its data from various literature, NCBI, protein data
Lactamase
bank [2] and other mediums. BLAD is based at the Aligarh Muslim
Database
University in the Interdisciplinary Biotechnology Unit. BLAD has
four search fields on their site: database, resistance, PDBS, and (BLAD) provides
genome. 3D structural
information
When looking at their database tab, users are able to see NCBI specifically on
cross-linked information about sequences, specifically looking at beta-lactamases
nucleotides and proteins. This data can also be exported for the and is updated
entry of interest. Under the resistance tab, information about beta-
regularly.
lactamases that confer resistance to antimicrobial drugs is available.
PDBS, or Protein Data Bank file formatting, has three-dimensional Data types Beta-lactamase
structural information on beta-lactamases, their variants, and captured
associated ligands. Lastly, the genome tab provides information of Organisms Bacteria
the plasmids that contain the beta-lactamase gene and identifying
Contact
characteristics.
Research center Aligarh Muslim
University
References
Primary citation PMID 23943635
1. Danishuddin, M.; Hassan Baig, M.; Kaushal, L.; Khan, A. (https://pubmed.
U. (2013). "BLAD: A comprehensive database of widely ncbi.nlm.nih.gov/
circulated beta-lactamases" (https://doi.org/10.1093%2F 23943635)
bioinformatics%2Fbtt417). Bioinformatics. 29 (19):
2515–2516. doi:10.1093/bioinformatics/btt417 (https://do Access
i.org/10.1093%2Fbioinformatics%2Fbtt417). Website BLAD (http://ww
PMID 23943635 (https://pubmed.ncbi.nlm.nih.gov/2394 w.blad.co.in/cont
3635).
act.php)
2. Sussman, Joel L.; Lin, Dawei; Jiang, Jiansheng;
Miscellaneous
Manning, Nancy O.; Prilusky, Jaime; Ritter, Otto; Abola,
Enrique E. (1998). "Protein Data Bank (PDB): Database Bookmarkable yes
of Three-Dimensional Structural Information of entities
Biological Macromolecules" (https://doi.org/10.1107%2F
s0907444998009378). Acta Crystallographica Section D. 54 (6): 1078–1084.
doi:10.1107/s0907444998009378 (https://doi.org/10.1107%2Fs0907444998009378).
PMID 10089483 (https://pubmed.ncbi.nlm.nih.gov/10089483).

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