82-P01.91.700043-01 GE300 GE320 Service Manual

Electrolyte Analyzer
Model: GE300/GE320
Service Manual
For In Vitro Diagnostic Use
Intellectual Property Rights
Genrui Biotech Inc. (hereinafter called Genrui) owns the copyright to

this unpublished manual and intends to maintain it as confidential. This
publication is to be used solely for the purposes of reference for Genrui
equipment.
Genrui owns this manual and all intellectual property rights (including
copyright) in this manual. Nobody is allowed to use, disclose or let
others obtain part or whole information of this manual in any manner
whatsoever without the written permission of Genrui. Nobody is
allowed to take the following actions to part or all contents of this
manual, including (but not limited to) shoot, reproduce, copy, or
translate it into other languages without the written permission of
Genrui.
Genrui reserves the final explanation right to this manual.
Genrui reserves the right to modify the content of this manual without
prior notice.
Genrui reserves the right to make technical alterations without prior

notice.
Genrui reserves the right to change the product specifications without

prior notice.
Item No.: P01.91.700043-01
I
Statement
Regarding this manual, Genrui will not take any warranty responsibility,
expressed or implied, including (but not limited to) warranties of
merchantability and fitness for any particular purpose.
Genrui is responsible for safety, reliability and performance of this

equipment only in the conditions that:
 All installation operations, expansions, readjustment,

modifications and repairs of this product are conducted by Genrui
authorized personnel.
 Related electrical appliances conform to National Standards.
 The product is used in accordance with the operation guide.
Genrui will not take the responsibility for the products’ safety, reliability
and performance based on the following situations:
 Components are disassembled/reassembled, stretched and

readjusted.
 Products are not properly operated according to the Operation

Manual.
II
Warranty Service
Free service scope:
Where the equipments conform to the provisions of Genrui Warranty

Services Ordinance range can enjoy the free service.
Services to be charged:
(1) Services not included in Genrui Warranty Services Ordinance

range should be charged by Genrui.
(2) Damages caused by the following reasons should be charged for

the services, even in warranty period:
 Man-made damage
 Network voltage exceeds the equipment’s specified range
 Irresistible natural disasters
Genrui will not be responsible for the direct, indirect or eventual

damages and delays resulting from the following conditions (including
but not limited to):
 Use the instrument improperly
 Replace parts or accessories not approved by Genrui
 Repair the instrument by personnel not authorized by Genrui
III
Customer Service Department
Manufacturer: Genrui Biotech Inc.
Address: 4-10F, Building 3, Geya Technology Park, Guangming
District, 518106, Shenzhen, China
Website: www.genrui-bio.com
E-mail Address: service@genrui-bio.com
Tel: +86 755 26835560
Fax: +86 755 26678789
IV
 This analyzer can only be operated by test professionals, doctors
or laboratory technicians who have been trained by Genrui or its
distributors.
 It is important for the hospital or organization that employs this
equipment to carry out a reasonable service/maintenance plan.
Neglect of this may result in machine breakdown or injury of
human health.
 Be sure to operate the analyzer under the situation specified in
this manual; otherwise, the analyzer will not work normally and the
analysis results will be unreliable, which would damage the
analyzer components and cause personal injury.
 This equipment must be operated by skilled/trained professional

maintenance personnel.
V
Table of Contents
Chapter 1 Instrument Overview ............................................................ 1
1.1 Instrument Structure ................................................................ 1
1.2 Block Diagram of the Instrument ............................................. 4
1.3 Each Module’s Function and Components.............................. 5
1.3.1 Sampling Module .......................................................... 5
1.3.2 Distribution Valve Module .............................................. 6
1.3.3 Peristaltic Pump Module ............................................... 7
1.3.4 Electrode Module .......................................................... 8
1.3.5 CO2 Module ................................................................... 9
Chapter 2 Software Upgrade .............................................................. 10
Chapter 3 Software Debugging .......................................................... 11
3.1 Functional Test ...................................................................... 12
3.1.1 COM ............................................................................ 12
3.1.2 Print Test ..................................................................... 13
3.1.3 CO2 Test ...................................................................... 13
3.1.4 Card ............................................................................. 14
3.1.5 Probe Up ..................................................................... 14
3.1.6 Probe Down................................................................. 14
3.1.7 Valve Sensor ............................................................... 14
3.1.8 Location Sensor .......................................................... 14
3.1.9 Pump ........................................................................... 15
3.1.10 Distribution Valve....................................................... 15
3.1.11 Tube Cleaning ........................................................... 15
3.1.12 Aging Test .................................................................. 15
3.2 Restore Factory Settings ....................................................... 16
3.3 Modify Standard A, B Concentration Value ........................... 17
3.4 Modify Slope Factor .............................................................. 18
VI
Chapter 4 Maintenance and Service .................................................. 19
4.1 Maintenance .......................................................................... 19
4.1.1 Daily Maintenance ....................................................... 19
4.1.2 Weekly Maintenance ................................................... 19
4.1.3 Liquid System Inspection ............................................ 20
4.1.4 Deprotein Solution Instruction ..................................... 22
4.2 Service ................................................................................... 23
4.2.1 Common System Errors .............................................. 23
4.2.2 Ion Calibration and Measurement Abnormal............... 24
4.2.3 CO2 Calibration and Measurement Abnormal ............. 27
4.2.4 Common Liquid System Errors ................................... 29
4.3 Common Mechanical Parts’ Assembly and Dismantlement .. 31
4.3.1 Dismantlement and Assembly of Distribution valve .... 31
4.3.2 Dismantlement and Assembly of Peristaltic Pump...... 35
4.3.3 Dismantlement and Assembly of Sampling Module .... 37
4.3.4 Dismantlement and Assembly of Aspirating Cup ........ 42
4.3.5 Disassembly and Installation of Electrodes ................ 46
4.3.6 Dismantlement and Assembly of Liquid Location Sensor
.............................................................................................. 48
4.3.7 Dismantlement of CO2 Component ............................. 49
Appendix 1 Liquid System Diagram ................................................... 52
VII
Chapter 1 Instrument Overview

1.1 Instrument Structure
1---Sample probe 2---CO2 module
3---Aspirating cup 4---Touch screen
5---Power indicator 6---Electrode window
7---Front panel
Fig. 1-1-1 Front view of the instrument
1
1---Thermal printer 2---Reagent chamber
Fig. 1-1-2 Instrument overview
2
1---Electrode module 2---Standard C pump
3---Solenoid valve 4---Waste pump
5---CO2 reaction chamber 6---Liquid Location sensor
7---Distribution valve 8---Peristaltic pump
Fig. 1-1-3 Instrument view with front panel opened
3
1.2 Block Diagram of the Instrument
Probe
Display
Distribution
Memory Valve
Main MCU
Peristaltic
COM
Pump
R Card Digital
Potentiometer
Auxiliary MCU
Positioner
Barcode Thermal Printer AD Board
Fig. 1-2 Block diagram of the instrument
4
1.3 Each Module’s Function and Components

1.3.1 Sampling Module
The sampling module consists of sample probe, upper and lower

sensors, motor drive part, as shown in Fig. 1-3-1. The sampling
module moves up and down with the lead screw through the motor,
moves up to aspirate the sample and moves down to the aspirating
cup and aspirate standard A, standard B and standard C. This module
belongs to part of the liquid system.
Fig. 1-3-1
5
1.3.2 Distribution Valve Module
The distribution valve module consists of the distribution valve,

mounting plate, location sensor and motor, as shown in Fig. 1-3-2. The
distribution valve module realizes the liquid path switch between
standard A, standard B and the air by accurate location sensor
resetting and precise stepping motor rotation, so to ensure a smooth
path flow. This module is very important to the liquid system.
Fig. 1-3-2
6
1.3.3 Peristaltic Pump Module
The peristaltic pump module consists of pump head, pump tube, tube
support, mounting plate and motor, as shown in Fig. 1-3-3. The motor
of the peristaltic pump module drives the pump head to rotate and
realize the liquid pumping by squeezing and releasing the pump tube
alternatively. This module is the power source of the whole liquid
system.
Fig. 1-3-3
7
1.3.4 Electrode Module
The electrode module consists of ion selective electrodes, reference

electrode and A/D signal board, as shown in Fig. 1-3-4. This module is
used to test each ion’s concentration of the sample.
Fig. 1-3-4
8
1.3.5 CO2 Module
The CO2 module consists of shell, peristaltic pump, solenoid valve,

reaction pool, pressure sensor and PCB board, as shown in Fig. 1-3-5.
This module is used to test CO2 concentration of the sample.
Fig. 1-3-5
9
Chapter 2 Software Upgrade
Chapter 2 Software Upgrade

If you need to upgrade software for GE300 series Electrolyte Analyzer,
please refer to GE300 series program burning method to install the
required software and connect the programmer well to upgrade the two
MCU according to the software upgrade requirements.
Note: While burning GE300_vx.xx_driver.hex (x.xx is the version

number), connect the interface to JP6; if burning
GE300_vx.xx_print.hex (x.xx is the version number), connect the
interface to JP5, as shown in the following figure.
JP5
JP6
10
Chapter 3 Software Debugging

In the “Maintain” interface, keep pressing the lower right corner of the
display until popping out an input keyboard, then input password
“860755” and click “Enter” to enter the interface as shown in Fig. 3-1.
Fig. 3-1
11
3.1 Functional Test
Click “Basic Test”, then the interface as shown in Fig. 3-2 displays.
Fig. 3-2
3.1.1 COM
This function is to test whether the instrument and PC communication

works normally or not. Make sure the serial port cable connected with
the PC well before the test, and the instrument’s COM setting should
be consistent with the externally connected instruments, then switch
the external instruments to be hexadecimal display mode. Click “COM”
in Fig. 3-2, if communication is normal, it will display “FF” on the PC.
12
3.1.2 Print Test
This function could test the inner thermal printer works normally or not.
Make sure there is printing paper inside, then click “Print Test” in Fig.
3-2, if the printer is normal, it will display the instrument model and
software version on the printing paper.
3.1.3 CO2 Test
This function is optional. When the instrument model is GE320, you

can test the CO2 liquid test component. You can also test whether the
acid pump, the waste liquid pump, the stirrer, the CO 2 liquid location
sensor, the solenoid valve and the pressure value are normal.
Acid Pump: Click “Acid Pump”, the acid pump starts to work.
Waste Pump: Click “Waste P.”, the waste pump starts to work.
Stirrer: Click “Stir”, the stirrer starts to work.
CO2 Liquid Location Sensor: Click “CO2 Sensor”, “×” is displayed if

failure occurs.
Solenoid Valve: Click “Valve”, the solenoid valve starts to work.
Pressure Value: Click “Pa” and press the “Aspirate” key to aspirate
sample, the current testing pressure is displayed.
13
3.1.4 Card
This function could test whether the reagent card could be detected or
not. Click “Card” in Fig. 3-2, if a valid card could be detected, it will
display “√” on the right side, otherwise display “×”.
3.1.5 Probe Up
This function could test whether the upper location sensor of the probe
works normally or not. Click “Probe Up” in Fig. 3-2, if the upper location
sensor works normally, it will display “√” on the right side, otherwise
display “×”.
3.1.6 Probe Down
This function could test whether the lower location sensor of the probe
works normally or not. Click “Probe Down” in Fig. 3-2, if the lower
location sensor works normally, it will display “√” on the right side,
otherwise display “×”.
3.1.7 Valve Sensor
This function could test whether the valve sensor works normally or not.
Click “Val Sensor” in Fig. 3-2, if the valve sensor works normally, it will
display “√” on the right side, otherwise display “×”.
3.1.8 Liquid Location Sensor
This function could test whether the liquid system location sensor
works normally or not. Click “Loc Sensor” in Fig. 3-2, if the location
sensor works normally, it will display “√” on the right side, otherwise
display “×”.
14
3.1.9 Pump
This function could test whether the peristaltic pump motor works
normally or not. Click “Pump” in Fig. 3-2 and observe whether the
peristaltic pump motor rotates normally or not.
3.1.10 Distribution Valve
This function could test whether the distribution valve motor works
normally or not. Click “Allot Val” in Fig. 3-2 and observe whether the
valve motor rotates normally or not. The distribution valve motor
rotation is unobvious, please observe or listen if there is rotating sound.
3.1.11 Tube Cleaning
This function is used to clean the liquid path and electrodes before
packaging the instrument after the production test is complete.
3.1.12 Aging Test
This function is for production aging test, it’s safe to ignore them.
15
3.2 Restore Factory Settings
This function could restore factory settings. Click “Initialize” under the
service interface to enter the initialize interface. Click “Yes” to enter into
the interface as shown in Fig. 3-3. After the initialization, all the data
will be deleted, so do not execute this function without the owner’s
agreement. Use with caution.
Fig. 3-3
16
3.3 Modify Standard A, B Concentration Value
Under the service interface, click “Set STD” to enter into the interface
as shown in Fig. 3-4. Click the corresponding ion’s A, B value to modify
the concentration value of standard A and B, so as to make the
concentrations be consistent with the tested values and get more
accurate results.
Fig. 3-4
17
3.4 Modify Slope Factor
Under the service interface, click “Set Slope” to enter into the interface
as shown in Fig. 3-5. Click the corresponding ion button to modify the
corresponding slope coefficient, set the calibration slope within a
certain range. Modifying the slope factor only affects the slope of the
calibration and does not affect the measured value. When the
calibration slope does not pass and is urgently needed, the calibration
slope can be modified temporarily and you can perform quality control.
Fig. 3-5
18
Chapter 4 Maintenance and Service

4.1 Maintenance
4.1.1 Daily Maintenance
1). Check the tubes and fluidic system to make sure it’s unobstructed.
2). Routinely check the inventory of standard A (electrode drifting

solution), standard B (slope correction solution) and standard C,
replace them in time.
3). Drain the waste bottle every day and clean the waste bottle.
4.1.2 Weekly Maintenance

1). Check the aspirating cup once a week and clean the dried solution
and sample to keep the aspirating cup clean.
2). Check the inventory of the electrode filling solution, if less than 2/3
of the volume, replace it timely.
3). Check whether there is salt deposit around the electrode pole, if any,
use a wet cotton ball to clean it and use a dry cotton ball to dry it, then
reinstall it.
4). Check the sample stopped position, if unmatched, adjust it or test

the liquid location sensor.
5). Perform deproteinization with deprotein solution once a week.
19
6). Observe the electrodes’ potential millivolt value under the potential
tracking interface to evaluate whether need to replace the reference
electrode and reference filling solution or not.
7). Make sure the instrument is well grounded.
4.1.3 Liquid System Inspection

While in use, if found the aspirating speed or volume is abnormal, or
abnormal sound occurred in the aspirating process, please check if the
tube is clogged or there is air leakage.
1). Perform the ion calibration program, observe the liquid flowing
situation inside the electrode channel and the tube, the normal
situation while switching standard A and standard B is big segments of
standard solution separated by big segments of air. While executing
CO2 calibration program, the whole tube of standard C is full of lactic
acid without bubbles. Observe whether the total liquid volume of the
CO2 reaction chamber is normal or not (the reaction pool total volume
is decided by the adjustment of the sample aspirating amount and
standard C amount), and whether there is no standard C or the total
reaction liquid volume exceeds the reaction pool’s total volume.
2). Check the tubes segment by segment. Pull out the waste tube,
probe tube and distribution valve outlet tube, then use a syringe to
push through the tube and solve the problems like poor connection,
tube blockage, tube conglutination, cracking etc..
20
3). If there’s big amount of bubbles at the connector and contact pin’s
position, it is air leaking; If abnormal sound occurred while the
peristaltic pump is rotating, maybe the pump tube is conglutinated or
clogged, check each tube and the pump tube segment by segment.
4). Reconnect the tubes, if there is air-leaking between the electrodes,

please check the sealing washer, or observe if the electrode
membrane is damaged and leaks the filling solution; if the electrode is
clogged, please check if there is foreign material blocking the electrode
channel (prohibit using through-hole needle to unclog the channel, in
case of damaging the electrode membrane), if the reference electrode
is clogged, and there are white crystals inside the channel, generally
the membrane is leaking, report for repairment timely (users can
temporarily use the through-hole needle to unclog the channel, soak it
into the distilled water and dissolve the crystals, then replace the
reference filling solution and reconnect the tubes to calibrate).
5). If the tube has good air impermeability, check if the tube is clogged
or the junction is disconnected.
6). If the sample probe is clogged, use the through-hole needle to

unclog the probe after it is lifted up. use. If the aspirating cup is clogged,
remove the aspirating cup’s screws and take out the components, then
disassemble the silicon cover to take out the silicon and unclog the
hole to remove the protein residual and other wastes, do the regular
inspection every month.
21
7). Timely drain the tube connecting the CO 2 pool cover with the
pressure sensor. Clean the inner side of CO2 reaction chamber, take
down the reaction pool cover, remove the protein residual and unclog
the waste outlet, then re-assemble them and connect the tubes well. If
the reaction pool’s air-leaking, report for repairement timely.
8). If the pump tube is severely deformed (as shown in the following
figure), it will lead to insufficient aspirating amount, which can not
satisfy the instrument’s testing range, the tube should be replaced in
time.
Pump tube severely deformed,

needs to be replaced
4.1.4 Deprotein Solution Instruction

The deprotein solution is effective to remove the protein fiber in the
tube, without any side effect to the electrodes. Store at around 5℃ in
the refrigerator when not in use.
After the deproteinization, it will automatically perform the cleaning

procedure. Repeat the ion calibration several times until the electrode
slope is stable.
22
4.2 Service
4.2.1 Common System Errors
Problems Possible reasons Solutions
Turn on the power

Power switch off
switch
Screen no Re-insert the power

Power supply disconnected
display plug
Display signal cable Re-insert the display

loosened interface cable
The LCD display contrast Enter into contrast

Display dim or
changed with the interface to adjust the
too dark
environment instrument’s contrast
Replace with new

No printing paper
printing paper
The printing paper stuck after

Clear the stuck area
tearing off the paper
Printer not
Reversely installed the Reinstall printing
working
thermal printing paper paper
Reconnect the
The printer interface cable
printer interface
loosened
cable
23
4.2.2 Ion Calibration and Measurement Abnormal

Standard A, B
Replace the reagents
reversely placed
Electrodes’ filling Replace the electrodes’
solution decreased filling solution
Slope
The electrode
abnormal Use the deprotein solution
membrane absorbed
to clean
too much protein
Replace the corresponding
Electrodes invalid
electrodes
Use reliable ground cable,
Poorly grounded
check whether it is loose
Electrode socket,
Re-insert it tightly or replace
contact pin poorly
the socket
contacted
Electrode membrane
Replace the electrodes
leakage
Power voltage
Add the AC
Slope unstable unstable, with
stabilified-voltage power to
electrostatic
eliminate the static
interference
Solution inside the
Check if the tube is clogged
tube containing
or air-leaking
bubbles
Electrodes inactivated
or activation time too Recalibrate after activation
short
24

Take down the ref.
Bubbles at the ref.
electrode and forcibly toss
electrode membrane
out the bubbles
Ref. electrode filling Replace the ref. electrode’s
solution unsaturated filling solution
All ion Electrode cable poorly
Check the electrode cable
electrodes’ mV connected
value display AD module works Test AD module works
abnormally normally or not normally or not
Check the liquid system,
Aspirating standard A, distribution valve, peristaltic
B failed or not enough pump, liquid loc sensor
work normally or not
Ref. electrode invalid Replace the ref. electrode
Take down this electrode
Bubbles at this ion
and forcibly toss out the
electrode membrane
bubbles
Electrode contact pin
poorly contacted with
Single ion
the socket or Check the socket on the AD
electrode’s mV
electrode socket board damaged or not,
value display
damaged which leads replace the AD board
abnormally
to void value or
abnormal
While extracting mV Check, adjust the liquid
value, the electrode is system, make sure all the
not soaked electrodes are soaked
25

This electrode
membrane leaking or
filling solution too Replace the electrode
small to soak the
silver
Check the electrode failure
cause, use the deprotein
solution to soak the
Electrode problem
electrode, replace the
electrode, add in filling
solution
The sample is not in Check if the liquid system
place or the solution normal, the test solution
does not reach the filling in the electrode and
designated position the liquid loc sensor normal
Test data Reagents used up or
Replace the reagents
abnormal deteriorated
Replace the reference
Reference electrode
electrode filling solution or
or ion electrodes not
the ion electrode filling
good
solution
Restore the calibration
Test data too Calibration factor
factor value to be original
big or too small value abnormal
value 1.00
26
4.2.3 CO2 Calibration and Measurement Abnormal

Replace the standard C,

re-perfuse the liquid
Without standard C in
system, make sure
the tube
standard C tube full of
lactic acid
Standard C pump tube Restore the pump tube
conglutinated or or replace the tube
damaged according to the abrasion
Check one by one,
The reaction pool and
replace the
connecting tubes air
corresponding
leaking
CO2 calibration components
value almost Tubes connected with Remove tubes of the
zero the pressure sensor pressure sensor, drain
are liquid obstructed the liquids
Standard C or CO2
Replace standard C or
solution severely
CO2 solution
deteriorated
Connect the plug tightly,
Stirring motor
replace the stirring motor
damaged, not working
assembly
Insert the plug, CO2
Pressure sensor
module flat cable tightly
damaged or CO2 board
or replace the pressure
failure
sensor, CO2 main board
27
Tubes connected with Remove tubes of the

the pressure sensor pressure sensor, drain
are liquid obstructed the liquids
The reaction pool and
connecting tubes Check CO2 system
slightly air leaking
Sampling pump tube,
standard C tube aging, Replace the pump tube
inaccurate sampling
CO2 calibration Waste pump tube too
Cut short the pump tube
value low, long, can’t be tightly
and reconnect
unstable or pressed
inaccurate test CO2 solution
Replace the solution
results deteriorated
The cooling fan of CO2
module not working Check the plug or
which leads to module replace the fan
temperature change
The venting solenoid
Replace the solenoid
valve leaking or can’t
valve
be tightly pressed
Pressure sensor Replace the pressure
damaged sensor
CO2 calibration Venting valve not Replace the venting
value exceeds working valve
the max. range Waste tube clogged or Unclog the waste tube or
28
waste pump tube replace the waste tube

conglutinated
Pressure sensor Replace the pressure
damaged sensor
4.2.4 Common Liquid System Errors
Replace with a new

Pump tube damaged
pump tube
Check if the tube clogged
Tube clogged
or air leaking
If the motor damaged or
No aspiration Peristaltic pump didn’t powered on, check the
rotate corresponding
connectors
Replace with an
Pump tube too long appropriate length pump
tube
Replace with a new
Distribution valve
distribution valve location
location sensor failure
sensor
Aspirate
Replace with a new
standard A, B Distribution valve axle
distribution valve axle,
failed failure or clogged
check if it is clogged
Clean or replace with a
Aspirating cup clogged
new aspirating cup
29
Tube clogged or Check if the tube’s

leaking clogged or leaking
Switch to manually
adjusting the sampling
Liquid system location
mode, observe if need to
sensor failure
The solution or replace the liquid location
sample could not sensor or tube.
fill in the Aspirating amount Increase the aspirating
electrode, which insufficient amount
leads to Observe whether the
abnormity liquid shift to one side of
Peristaltic pump tube
the tube to decide
too loose or too tight
replace the pump tube or
not
If there’s air leakage at
the bubble appeared at
the front connector, cut
There are
Connector air leaking, off a small section of the
homogeneous
distribution valve’s tube, then reconnect,
and continuous
O-type ring abraded or replace with a new
bubbles in the
clogged O-type ring, clear the
tube
distribution valve hole or
replace with a new
distribution valve
30
4.3 Disassembly and Installation of Common
Mechanical Parts
4.3.1 Disassembly and Installation of Distribution Valve
1). Turn off the power.
2). Pull out the tubes connected with the distribution valve, avoiding
liquids flowing into the instrument. (As shown in the figure below)
31
3). Use the screwdriver to remove the four flat screws and take down
the distribution valve assembly. (As shown in the figure below)
4). Use the screwdriver to remove the pan head screws that fix the
sensor, the hex wrench to take apart the distribution valve fixing plate,
then respectively take down the distribution valve’s fixing plate and
sensor. (As shown in the figure below)
32
5). Use the hex wrench to loosen the two stop screws and take down
the distribution valve shell and axle. (As shown in the figure below)
33
6). Pull out the distribution valve’s axle, check if there’s any problem on
the O-type rubber ring, if yes, replace it. (As shown in the figure below)
7). Use the screwdriver to remove the three flat screws, then separate
the shell, cover and pressure plate, check if the O-type rubber ring’s
abraded, if yes, replace it. (As shown in the figure below)
34
8). If without above problems, use the multimeter to check whether the
sensor has problem or not.
9). If no problem, reversely assemble it as the dismantling steps.
10). Cleaning, wipe clean the instrument surface.
11). Execute recalibration program.
4.3.2 Disassembly and Installation of Peristaltic Pump

1). Turn off the power;
2). Take down the tube twining on the peristaltic pump, then check if it
is severely deformed. If it’s out of the instrument’s adjustable range,
should be replaced. (As shown in the figure below)
35
3). Use the screwdriver to remove the four flat screws, take down the
peristaltic pump assembly. (As shown in the figure below)
4). Use the hex wrench to remove the two M3 pump head’s tightening
screws (During this process, check if the pump head’s tightly fixed on
the electrode axle), then take down the pump head. (As shown in the
figure below)
5). Check whether each rotating point of the pump head running
smoothly or not.
6). If no problem, assemble it reversely as the dismantling steps.
8). Execute the recalibration program.
36
4.3.3 Disassembly and Installation of Sampling Module

1. Disassembly and Installation of the Single Probe Module
1). Lift the probe to the sampling position, turn off the power and take
down the probe decoration. (As shown in the figure below)
37
2). Take down the probe connected tube, remove the probe and check
if there’s dirt inside the probe, if yes, use the through-hole needle to
clean the dirt, then use the distilled water to clean and dry it. (As shown
in the figure below)
38
2. Disassembly and Installation of the Double Probe Module
1). Turn off the power, remove the sampling probe cover. (As shown in
the figure below)
2). Remove the probe connected tube, use the screwdriver to loosen
the six screws fixing the double probes, take down the probes and their
clamp, check if there’s dirt inside the probe, if yes, use the
through-hole needle to clean the dirt, then use the distilled water to
clean and dry it. (As shown in the figure below)
39
3. Disassembly and Installation of the Motion Component
1). Use the screwdriver to remove the 10 screws fixing the back cover
and take it down. (As shown in the figure below)
2). Use the screwdriver to remove the 4 hex socket screws fixing the
motion component, then take out the motion component. (As shown in
the figure below)
3). Check if the two microswitches is normal or not.
40
4). Check the tight degree of the synchronous belt, if too loose, adjust it
appropriately.
5). Check if there’s enough lubricating oil at the screw nut and the
bearing.
6). Check if each screw is loosened or not.
7). If no problem, install it reversely as the previous steps. (While

installing the probes and clamp onto the probe holder, pay attention to
adjust the probes and sampling component’s position and angle, make
sure the fixed probes aligned to the aspirating cup’s two guide holes.
There’s strict requirement for the probe’s installing height, as shown in
the following figure, one high and one low, the height difference is 3mm,
the lower probe is 5mm above the surface, while the upper probe 8mm
above the surface.)
41
4.3.4 Disassembly and Installation of Aspirating Cup

1. Disassembly and Installation of the Single Probe Aspirating
Cup
1). Take down the aspirating cup’s decoration. (As shown in the figure
below)
2). Use the screwdriver to take down the two M3 screws fixing the
aspirating cup, remove the tubes connecting with the aspirating cup,
then take down the aspirating cup. (As shown in the figure below)
42
3). Press on the two button placement of the aspirating cup shell to
disassemble it, check if there’s any problem, then use the distilled
water to wash away the salt deposit, etc.. (As shown in the figure
below)
43
2. Disassembly and Installation of the Double Probe Aspirating

Cup
1). Take down the aspirating cup’s decoration. (As shown in the figure
below)
2). Pull out the tube connected with the aspirating cup, remove the two
M3 inner hexagon screws fixing the lower part of the aspirating cup,
then take it out. (As shown in the figure below)
44
3). Use the hex wrench to remove the two hexagon screws fixing the
Aspirating cup’s silica gel cover. Take part the aspirating component,
check if there’s any problem, then use the distilled water to wash away
the residual proteins or salt deposit, etc.. (As shown in the figure
below)
4). After the cleaning, dry it, then install it reversely as the
disassembling steps(While doing the installation, take care to adjust
the position of the Aspirating cup, make sure the double probes
aligning at the Aspirating cup’s guide holes).
45
4.3.5 Disassembly and Installation of Electrodes

1). Pull out all the electrode plugs, then disconnect the electrode
module with the drain tube and sampling tube. (As shown in the figure
below)
2). Loose the electrodes’ fixing nut. (As shown in the figure below)
46
3). Pull out each electrode from the two sides to disassemble the
electrode module and the guide shaft. (As shown in the figure below)
4). Remove electrodes that need to be replaced.
5). Take a new same electrode.
6). Assemble the electrodes onto the guide shaft according to the
original sequence, take care to install the O type rubber ring well
between each electrode. (As shown in the figure below)
7). Tightly lock the electrode hold-down nut.
8). Connect the tubes well, respectively insert each electrode’s plug
into the corresponding socket.
47
4.3.6 Disassembly and Installation of Liquid Location

Sensor
2). Use the screwdriver to remove the two flat screws fixing the sensor
base, then take down the sensor base. (As shown in the figure below)
3). Use the screwdriver to remove the two sensor fixing screws and
take down the sensor. (As shown in the figure below)
4). Use the multimeter to check if there’s any problem, if yes, replace it;
otherwise install it reversely as the disassembling steps.
48
4.3.7 Dismantlement of CO2 Component

2). Loosen the M3 screws by hand directly, open the CO 2 door. (As
shown in the figure below)
3). Remove the pump tube of standard C pump and the tube
connecting the CO2 reaction chamber with the aspirating cup
component, use the screwdriver to take down the 4 screws fixing the
CO2 component on the CO2 shell fixing plate. Then pull out the CO 2
component slightly, take down the flat cable from the backside of CO 2
component. (As shown in the figure below)
49
4). Check whether CO2 reaction chamber is clogged or not.
5). Refer to 4.3.2 for the peristaltic pump’s disassembling steps, check
if the peristaltic pump head rotates smoothly, the pump tube is
adhesive or deformed.
6). Loosen the four M3 screws on both sides of the CO 2 component to

take out the fixing plate, and then check the CO2 main board.
50
7). Dismantle solenoid valves: Use M3 screwdriver to remove screws

fixing the solenoid valves’ fixing plate to take out the solenoid valves.
8). Dismantle CO2 reaction chamber component, loosen the two M3

screws fixing the reaction pool component from the back side, take
down the reaction pool, then use the hex wrench to loosen the four M3
inner hexagon screws fixing the reaction pool cover, then the reaction
pool cover could be taken down and the reaction pool could be cleaned.
Loosen the three M2 inner hexagon screws of the reaction bottom,
which fix the motor fixing plate, then the stirring motor component
could be taken down, as shown in the figure below:
9). Check the whole air impermeability of the CO2 reaction system,
make sure there is no blocking, air leaking and pollution, then install it
reversely according to the disassembling steps.
51
Appendix 1 Liquid System Diagram
Appendix 1 Liquid System Diagram
52
Add:4-10F, Building 3, Geya Technology Park, Guangming District,
518106, Shenzhen, China
Web:www.genrui-bio.com
P0 1 . 9 1 . 7 0 0 0 4 3- 0 1

82-P01.91.700043-01 GE300 GE320 Service Manual

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Electrolyte Analyzer

Genrui Biotech Inc. (hereinafter called Genrui) owns the copyright to

Genrui reserves the final explanation right to this manual.

Genrui reserves the right to make technical alterations without prior

Genrui reserves the right to change the product specifications without

Item No.: P01.91.700043-01

Genrui is responsible for safety, reliability and performance of this

 All installation operations, expansions, readjustment,

 Related electrical appliances conform to National Standards.

 The product is used in accordance with the operation guide.

 Components are disassembled/reassembled, stretched and

 Products are not properly operated according to the Operation

Free service scope:

Where the equipments conform to the provisions of Genrui Warranty

(1) Services not included in Genrui Warranty Services Ordinance

(2) Damages caused by the following reasons should be charged for

 Network voltage exceeds the equipment’s specified range

 Irresistible natural disasters

Genrui will not be responsible for the direct, indirect or eventual

 Use the instrument improperly

 Replace parts or accessories not approved by Genrui

 Repair the instrument by personnel not authorized by Genrui

 This equipment must be operated by skilled/trained professional

Chapter 1 Instrument Overview

1---Sample probe 2---CO2 module

3---Aspirating cup 4---Touch screen

5---Power indicator 6---Electrode window

Fig. 1-1-1 Front view of the instrument

1---Thermal printer 2---Reagent chamber

Fig. 1-1-2 Instrument overview

1---Electrode module 2---Standard C pump

3---Solenoid valve 4---Waste pump

5---CO2 reaction chamber 6---Liquid Location sensor

7---Distribution valve 8---Peristaltic pump

Fig. 1-1-3 Instrument view with front panel opened

1.2 Block Diagram of the Instrument

Fig. 1-2 Block diagram of the instrument

1.3 Each Module’s Function and Components

The sampling module consists of sample probe, upper and lower

1.3.2 Distribution Valve Module

The distribution valve module consists of the distribution valve,

1.3.3 Peristaltic Pump Module

1.3.4 Electrode Module

The electrode module consists of ion selective electrodes, reference

1.3.5 CO2 Module

The CO2 module consists of shell, peristaltic pump, solenoid valve,

Chapter 2 Software Upgrade

Note: While burning GE300_vx.xx_driver.hex (x.xx is the version

Chapter 3 Software Debugging

3.1 Functional Test

This function is to test whether the instrument and PC communication

3.1.2 Print Test

3.1.3 CO2 Test

This function is optional. When the instrument model is GE320, you

Stirrer: Click “Stir”, the stirrer starts to work.

CO2 Liquid Location Sensor: Click “CO2 Sensor”, “×” is displayed if

Solenoid Valve: Click “Valve”, the solenoid valve starts to work.

3.1.6 Probe Down

3.1.7 Valve Sensor

3.1.8 Liquid Location Sensor

3.1.10 Distribution Valve

3.1.11 Tube Cleaning

3.1.12 Aging Test

3.2 Restore Factory Settings