Performance Assessment: Sickle-Cell Trait (SCT) Infographic

Instructions:
1. Read the following articles :
a. Athletes with Sickle Cell Trait Article (pdf)
b. Sickle Cell Experimental Therapy (pdf), or Sickle Cell Experimental Therapy (original news
article)

2. Using information in these resources and what you’ve learned in this unit to create an
infographic that explains why inheriting an abnormal hemoglobin gene will cause an individual with SCT
to struggle with maintaining homeostasis during exercise and discuss the possible use of stem cells in
the treatment of the disease. Use google draw, or something you are familiar with, to make your
infographic.
a. You might recall that we did an activity titled “How do you transcribe and translate a gene?”
where we compared normal hemoglobin with the HbS (sickle cell) hemoglobin sequences. Look
for it in your google drive.

3. Include the following information on your infographic:

a. The change in the structure of DNA
b. The change in the structure of the protein
c. The change in the cell
d. The change in the function of the body system
e. How these changes affect homeostasis in the related body systems (circulatory, respiratory,
muscular)
f. How this condition can be treated using stem cells (and the role mitosis plays)
g. Include 2 or more relevant pictures (with captions)

4. Include a separate Reference List (in APA format) on a google doc that lists the references used
to complete the infographic. Use APA format. Include the references for both articles.
(www.citethisforme.com, Citation Machine, or use google doc “tools-explore”).

5. Save both the Infographic and the Reference List as pdf files. Turn in both to Canvas at the same
time. Remember: This counts as an assessment!
Grading Rubric
4 3 2 1

SCT affects Thoroughly explains Adequately explains Partially explains Does not correctly
Structure how structure is how structure is how structure is link structure to
Function related to function at related to function at related to function at function on all levels
all levels of all levels of all levels of and how SCT affects
organization organization and how organization and how them
and how SCT affects SCT affects them SCT affects them
them

Interactions Explains how SCT Explains how SCT Explains how SCT Explains how SCT
between will affect the will affect the affects the body, but affects the body, but
SCT and interactions between interactions between does not link to does not link to
three body body systems and body systems interactions between interactions between
systems how it causes the all three body body systems
symptoms of SCT. systems

Treatment Explains how the Explains how stems Explains how stems Mentions use of stem
Using Stem nature of stems cells cells are used for the cells are used for the cells without further
Cells allow for the treatment of SCT. treatment of SCT. explanation.
treatment of SCT. Discusses the role of
Discusses the role of mitosis in the
mitosis in the treatment process.
treatment process.

References Included APA Included reference Included APA Included reference

formatted reference for all sources used, formatted reference for only the two
for all sources used, including both for only the two articles, not outside
including both articles, but not in articles, not outside sources, not in APA
articles APA format sources format

Format *Uses phrases *Technical language *lacks examples as *Uses

*May use bullet not appropriate sentences/wordy
points’ explained/simplified *lacks pictures * font/size/color
*Technical language *Includes 2 or more makes it difficult to
explained or irrelevant pictures read
simplified accurately
*Includes examples
as appropriate
*Includes 2 or more
relevant pictures
*Use of easily read
font/size/color