1. Discuss gigantism & acromegaly.

What makes them different even there is an over

production of the growth hormone? (10 points)
2. What is Grave's Disease? Discuss the cause, symptoms, treatment and management. (10
points)
3. Discuss the effects of aging on the Endocrine System (10 points)
1.

Gigantism

Gigantism is a very rare condition that happens when a child or adolescent has high levels of
growth hormone in their body, which causes them to grow very tall. Gigantism is treatable, but early
diagnosis is crucial to prevent excessive height and other complications.

Acromelagy

Acromegaly is a rare condition where the body produces too much growth hormone, causing
body tissues and bones to grow more quickly. Over time, this leads to abnormally large hands and feet,
and a wide range of other symptoms.

Difference between Gigantism and Acromelagy

Gigantism is in the skeletally immature and is proportional. Acromegaly occurs in skeletally

mature people and only affects those bones that can keep growing.

2. What is grave’s disease

Graves' disease is an immune system disorder that results in the overproduction of thyroid
hormones (hyperthyroidism). Although a number of disorders may result in hyperthyroidism, Graves'
disease is a common cause. Thyroid hormones affect many body systems, so signs and symptoms of
Graves' disease can be wide ranging.

Causes of Grave’s Disease

Graves' disease is caused by a malfunction in the body's disease-fighting immune system. It's
unknown why this happens.

Symptoms of Grave’s Disease

 Anxiety and irritability.

 A fine tremor of the hands or fingers.
 Heat sensitivity and an increase in perspiration or warm, moist skin.
 Weight loss, despite normal eating habits.
 Enlargement of the thyroid gland (goiter)
 Change in menstrual cycles.
 Erectile dysfunction or reduced libido.
 Frequent bowel movements.
 Treatment of Grave’s disease

 Radioactive iodine therapy

 Anti-thyroid medications
 Beta blockers
 Surgery

3.

Esndocrine system undergoes age-related changes that negatively affect its functioning. As a
result of these changes, older people are more prone to disturbed sleep patterns, have a reduced
metabolic rate, lose bone density, accumulate body fat, and show increases in blood glucose.