You are on page 1of 24

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**


SANJIVANI Question Series
Subject : Biology Topic – Principles of Inheritance and Variations

1. Select the set of correct statements - 6. Incorrect about hemophilia -


A. Mendel publish his work in 1855. 1) Sex linked
B. Inheritance of flower colour in Dog plant 2) Blood clotting is hastened
is an example of co-dominace.
3) Queen Victoria was a carrier of hemophilia.
C. Karl Landsteiner was one of the
rediscovers of Mendel’s work. 4) Male child will become hemophilic if mother
is haemophilic.
D.T.H. morgan worked upon Tiny fruitfly.
7. Read the following statements -
1) A, B and C 2) B and C
3) D only 4) B, C ad D A. Birds show female heterogamety

2. Life span of Tiny fruitfly is - B. Sickle cell anemia is a sex linked

1) 2 weeks 2) 1 months C. In phenylketonuria, phenylalanine


hydroxylase enzyme is deficient.
3) 2 months 4) 1 year
3. All of the following are examples of male Which set represents true statements?
heterogamety, except one - 1) A only 2) B only
1) Grasshopper 2) Human 3) A and B 4) A and C
3) Birds 4) Cockroach 8. Long furrowed tongue and short stature are
4. All of the following syndromes have similar features of -
number of chromosomes except one -
1) Down syndrome
1) Turner's syndrome
2) Klinefetter's syndrome
2) Klinefelter's syndrome
3) Turner's syndrome
3) Down's syndrome
4) Pater's syndrome
4) Edward's syndrome.
9. Select the mismatch -
5. In which of the following conditions, females
have rudimentary ovary and lack secondary 1) T.H. Morgan - Tiny fruitfly
sex characters.
2) G.J. Mendel - Pea plant
1) Klinefelter's syndrome
3) Incomplete dominance - Snapdragon
2) Turner's syndrome
4) Karl Correns - Chromosomal theory of
3) Down's syndrome
inheritance.
4) Cat cry syndrome
Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 1
10. Experimental verification of chromoso'mal 15. Read the following statements and answer the

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
theory of inheritance is as done by - question following it -
1) Sutton and Boveri 2) T.H. Morgan A - Inheritance is the basis of heredity.
3) W. Bateson 4) Hugo de Vries B - Round shape of seed is a dominant trait.
11. Mendel has chosen __P__ for his experiments. C - Mendel's work published in 1855.
He selected __Q__ true breeding purelines. D - Chromosomal theory of inheritance was
1) P - Sweet Pea, Q - 14 given by Sutton and Boveri.
2) P - Sweet Pea, Q - 7 E - Henking was one of the re-discoverer of
3) P - Garden Pea, Q - 14 Mendelian work.
4) P - Garden Pea, Q - 7 How many of the above statements are
12. A true breeding pureline chosen by Mendel correct?
shows ____________ trait inheritance and is
1) A, B, C, E 2) B, C, D, E
obtained by continuous _______pollination
for __________ generations. 3) A, B, D 4) All
1) Stable, cross, many 2) Unstable, self, many 16. Gregor Mendel worked on __1__ for __2__
3) Stable, cross, few 4) Stable, self, many. years to extract the laws of inheritance.
13. Four figures are shown below. Select the 1) 1 = Garden pea, 2 = 3
incorrect match. 2) 1 = Garden pea, 2 = 7
3) 1 = Sweet pea, 2 = 5
4) 1 = Sweet pea, 2 = 8
17. Which of the following is a recessive trait
selected by Mendel in garden peas?
1) P - Male Drosophila - XY sex chromosome 1) Green seed colour
2) Q - Female Drosophila - XX sex chromosome 2) Axial flower position
3) R - Constricted pea pod - Dominant trait 3) Green pod colour
4) S - 2 pairs of homologous chromosomes - G2
4) Both (1) and (3)
phase
14. Observe the given crosses (A and B) done in 18. In garden peas, Mendel has chosen ______pod
Drosophila. Select the incorrect statement. colour as dominant and ________ as recessive.
1) Violet, White 2) Green, Violet
3) Yellow, Green 4) Green, Yellow
19. Select the correct statement regarding given
figures (A and B).

1) y and w are more linked than w and m.


2) Recombinants will be more in number in
cross A than cross B. 1) A can be observed during meiosis -I
3) In cross A, parental type will be more than 2) A can be observed during meiosis -II
recombinants.
3) B can be observed during meiosis -I
4) In cross B, parental type will be more than
recombinants. 4) B can be observed during G-phase.

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 2


20. Given arrangement of homologous 25. All of the following contributed to Mendel's

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
chromosomes can be observed in - success except -
1) Mendel's selection of pea plant for experiments
2) Application of mathematical knowledge
3) Working on small sampling size at a time
1) G1 stage 2) G2 stage 4) Taking one character at a time.
3) Meiosis-II 4) Germ cell 26. How many of the following are dominant
21. Observe the diagrams given below and traits chosen by Mendel in hybridization
identify the wrongly matched option. experiments in garden peas?
(i) Violet flower colour
(ii) Constricted pod shape
(iii) Green seed colour
(iv) Wrinkled seed shape

1) A - G1 phase (v) Yellow pod colour

2) B - Gamete (germ cell) (vi) Terminal flower position


1) 0 2) 2
3) C - Meiosis-II
3) 3 4) 4
4) D - G2 phase A
27. Heterozygous tall pea plant is crossed with a
22. Among the following select the dominant trait dwarf pea plant. This is -
chosen by Mendel?
1) Dihybrid cross 2) Test cross
1) Seed colour - Green 2) Pod colour - Yellow
3) Co-dominance 4) Multiple allelism.
3) Both (1) and (2) 4) None. 28. Which of the following symbol in pedigree
23. Identify the traits [A -D) chosen by Mendel. analysis indicate mating between relatives?
Characters in pod Dominant Recessive
(Chosen by Mendel)
1) 2)
1. Colour A B
2. Shape C D
1) A - Green, B - Yellow, C - Inflated, D -
Constricted 3) 4)

2) A - Yellow, B -Green, C - Inflated, D -


29. Garden pea plant was taken.
Constricted
Character - Pod colour.
3) A - Green, B -Yellow, C - Constricted, D - Inflated
Dominant allele - G (for Green colour),
4) A - Yellow, B - Green, C - Constricted, D - Inflated Recessive allele - g (for Yellow colour).
24. __A__ pod shape was dominant over __B__ Pureline green pod was crossed with pureline
in Mendel's experiments. yellow pod to obtain F1 progeny. F 2 Progeny
1) A- Round, B- Wrinkled was obtained by selfing of F1 progeny. What
will be the ratio of yellow : green pod plants
2) A- Wrinkled, B- Round
in F2 progeny?
3) A- Inflated, B- Constricted 1) 2 : 1 2) 1 : 2
4) A- Constricted, B- Inflated. 3) 1 : 3 4) 3 : 1

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 3


30. Mendel crossed 2 true breeding pea lines for 35. On his work on monohybrid cross, Mendel

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
contrasting pod colour. F1 progeny shows all succeeded to extract -
pea plants with _______ pod colour.
1) 1 law 2) 2 laws
1) Violet 2) Green
3) 3 laws 4) 4 laws.
3) White 4) Yellow.
36. If the result of test cross is 1 : 1, what does it
31. When pure line tall pea plants were crossed indicate?
with dwarf pea plants, F 1 progeny was
1) The dwarf plant taken was homozygous
obtained which was all tall. Why dwarf were
dwarf
not observed in Fi progeny?
2) The dwarf plant taken was heterozygous
1) Allele for dwarfness was blended with allele
dwarf
for tallness.
2) Allele for dwarfness has not entered the 3) The tall plant taken was homozygous tall
gamete. 4) The tall plant taken was heterozygous tall.
3) Allele for dwarfness is a recessive allele. 37. In a monohybrid cross, law of segregation is
4) Allele for dwarfness shows incomplete proved by the presence of -
dominance. 1) All tall plants in F1 progeny
32. Few symbols are shown below in pedigree 2) 3/4th tall plants in F2 progeny
analysis. Which of the following means mating?
3) 1/4th dwarf plants in F2 progeny
4) All parental type in Fi progeny.
1) 2) 38. If F1 progeny completely resembles either of
the parental type, it is case of -
1) Normal monohybrid cross
2) Incomplete dominance
3) 4)
3) Co-dominance

33. Mendel crossed TT × tt. Which of the 4) Blending inheritance.


following is incorrect? 39. In which of the following cases, F 1 progeny
1) F1 progeny were all tall. does not resemble any of the parental type -
2) F2 progeny were all parental type. 1) Dominance - recessive relationship
3) In F1 progeny, blending has not occurred. 2) Pleiotropy
4) 50% intermediate phenotypes were observed 3) Co-dominance
in F2 progeny.
4) Incomplete dominance.
34. According to 'law of dominance' by Mendel,
40. Two set of traits of garden pea are shown in the
if in a gfine with heterozygous condition, a
diagram. Identify the dominant pair of traits
normal allele produces a normal enzyme then
another allele (modified allele) should
produce -
1) Normal enzyme
2) Non functional enzyme
3) Less efficient enzyme 1) A and C 2) B and D
4) Both (2) and (3). 3) A and D 4) B and C

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 4


41. Mendel has chosen two traits for pod shape 44. How many of the following statements are

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
as given in diagrams as A and B. Select the correct?
option with correct identification of trait and A - In heterozygous condition, if dominant allele
its nature produces a normal enzyme, then recessive
allele can produce a less efficient enzyme.
B - Genotype is an allelic arrangement in a gene.
C - Inheritance of flower colours in Snapdragon
is an example of co-dominance.
D - In ABO blood group system, an individual
possess 3 alleles.
1) 1 2) 2
1) A is representing full pod and is a recessive 3) 3 4) 4
trait. 45. If red flowered plants (RR) of Antirrhinum
2) B is representing full pod and is a recessive trait. species are crossed with white flowered plants
(rr) then expected Fi progeny is -
3) A is representing constricted pod and is a
dominant trait. 1) All with red flowers
2) All with white flowers
4) B is representing constricted pod and is a
recessive trait. 3) All with pink flowers
4) All with blue flowers.
42. Section of flower of garden pea is shown in
diagram with labellings (P-S). Removal of 46. 'A' type of sugar polymer is expressed on the
which part will result in emasculation? membrane of RBC if the genotype is -
1) iA iA or iA i 2) iA iA
3) iA iB 4) i i
47. Which of the following refers to the degree
by which the progeny differs from the parent?
1) Heredity 2) Mutations
3) Variations 4) Recombinations.
48. Identify the breed of cattle that have been
developed in Punjab from artificial selection
1) P 2) Q and domestication from wild cows -
3) R 4) S 1) Sahiwal 2) Murrah
43. In the given diagram a technique is being 3) Deoni 4) Gir
shown. Identify it. 49. Select the set of wrong statements -
A - Sexual reproduction was known to human
as a source of variation since 8000-10000 BC.
B - Mendel succeeded as he has taken small
sampling size for experiments.
C - Mendelian factors are actually chromosomes.
D - ABO Blood group is an example of multiple
allelism.

1) Emasculation 2) Artificial pollination 1) A, B, C 2) B, C


3) A, C, D 4) B, C, D
3) Vernalization 4) Etiolation

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 5


50. Mendel published his work in - 58. A and B are pedigree analysis of 2 diseases.

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
1) 1822 2) 1865 Select the correct statement -

3) 1882 4) 1884
51. Phenomenon of co-dominance is shown by -
1) iA I 2) iA iB
3) iB I 4) i i
52. Number of allelic forms for gene I (for
1) A represents autosomal dominant trait while
expression of blood groups) in a population is /
B represents autosomal recessive trait.
are -
2) A represents Y-linked trait while B represents
1) One 2) Two
linked trait.
3) Three 4) Four.
3) A represents autosomal recessive trait white
53. Which allele/s is required for the expression B represents X -linked dominant trait.
of blood group AB?
4) A represents autosomal recessive trait white
1) iA
2) i B B represents autosomal dominant trait.
3) Both iA and iB 4) iAB 59. Following pedigree analysis can be observed
in -
54. In Phenylketonuria, accumulation of which
compound in brain result in mental retardation
1) Phenylalanine 2) Tyrosine
3) Phenyl-pyruvic acid 4) Lactic acid.
55. Chromosome numbers 45 can be observed in
1) Klinefelter's syndrome
2) Down's syndrome 1) Colour blindness 2) Hypertrichosis

3) Turner's syndrome 3) Haemophilia 4) Myotonic dystrophy.

4) Sickle cell anemia. 60. In pea seeds, starch production is controlled


by 2 alleles - B and b. Bb genotype results in
56. Chromosome number becomes 47 in - synthesis of -
1) Turner's syndrome 1) High amount of starch, equivalent to BB
2) Sickle cell anemia 2) Low amount of starch, equivalent to bb
3) Down's syndrome and Klinefelter's syndrome 3) Intermediate amount of starch
4) Turner's syndrome and Klinefelter's syndrome. 4) Both (1) and (2) are possible.
57. Chromosome number 47, sterile male with 61. Starch synthesis in pea seeds are regulated
feminine features are observed in - by B and b alleles, bb genotype produces -
1) Klinefelter's syndrome 1) Large sized round seeds
2) Turner's syndrome 2) Small sized round seeds
3) Down's syndrome 3) Large sized wrinkled seeds
4) Phenylketonuria. 4) Small sized wrinkled seeds.

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 6


62. B and b are two alleles regulating starch 67. Which one of the following was not involved

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
synthesis in pea seeds. These effect following in rediscovery of Mendelian work?
phenotypes -
1) Hugo de Vries 2) Karl Correns
1) Grain size
3) Tshermak 4) Sutton.
2) Grain shape
68. T.H. Morgan worked on -
3) Both (1) and (2)
1) Sweet pea 2) Garden pea
4) Height of plant.
3) Grasshopper 4) Drosophila
63. Presence of intermediate grain size in pea
69. Life cycle of fruitfly is -
plants indicate the phenomenon of -
1) 1 week 2) 2 weeks
1) Normal dominance
3) 1 month 4) 2 months.
2) Incomplete dominance
70. Chromosomal theory of inheritance was
3) Co-dominance
experimentally verified by -
4) Multiple allelism.
1) Sutton 2) Boveri
64. Observe the phenotypic effects of a gene with
3) Sutton and Boveri 4) T.H. Morgan.
2 aleles - B and b in pea plant.
71. Chromosomal theory of inheritance was given
Genotype Grain Size Grain Shape
by Sutton and Boveri -
BB Large Round
1) Together in 1900
Bb Intermediate Round
2) Independently in 1900
Bb Small Wrinkled
3) Together in 1902
Which of the following extract is incorrect in
4) Independently in 1902.
concern to above facts?
72. Pea plants having seeds with Yellow colour
1) Gene shows incomplete dominance for grain
and Round shape (YYRR) were crossed with
size.
pea plants having seeds with Green colour
2) Gene shows normal dominant recessive and Wrinkled shape (yyrr). Expected
relationship for grain shape. phenotypic ratio in F1 progeny -
3) Gene is example of pleiotropic gene 1) 9 : 3 : 3 : 1
4) Gene shows co-dominance. 2) All with yellow coloured and round shaped
seeds
65. Identify the incorrect match -
3) 3 : 1
1) Incomplete dominance - Dog flower
4) All recombinants.
2) Co-dominance - Blood groups
73. According to Mendel, what was the ratio of
3) Male heterogamy - Human
gametes formed by YyRr?
4) Female heterogamy - Grasshopper.
1) YR : yr = 1 : 1
66. Mendelian work was rediscovered in -
2) YR : yr = 3 : 1
1) 1900 2) 1902
3) RY : yr : yR : Yr = 9 : 3 : 3 : 1
3) 1891 4) 1822
4) RY : yr : yR : Yr = 1 : 1 : 1 : 1

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 7


74. Gene mapping was developed by : 81. Sex determination in most of the birds is :

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
1) Alfred Sturtevant 2) T.H. Morgan 1) XO type 2) XY type
3) Sutton and Boveri 4) Hugo de Vries.
3) ZW type 4) Haplodiploidy
75. Alfred Sturtevant has done gene mapping for
the first time in : 82. Which of the following is not correctly matched?

1) 1865 2) 1900 1) Law of independent assortment - Mendel.


3) 1902 4) 1913. 2) Chromosomal theory of Inheritance - T. H.
76. Yellow bodied, white eyed female Drosophila Morgan.
was crossed with brown bodied, red eyed
male. In F2 progeny, parental type were found 3) X-body - Henking.
to be - 4) Gene mapping - A. Sturtevant.
1) 1.3% 2) 37.2%
83. Select the incorrect statement -
3) 62.8% 4) 98.7%
1) Law of independent assortment was based on
77. More the frequency of recombination -
monohybrid crosses.
1) More the distance between two genes
2) Dominance is not an autonomous feature of a
2) Less the distance between two genes
gene or the product that it has information for.
3) Less are the chances of crossing over
3) Mendel used mathematical approach to solve
4) More are chances of forming parental type.
biological problems.
78. X-body was first reported by :
4) Both (1) and (2).
1) Henking 2) Alfred Sturtevant
84. How many types of gametes can be produced
3) Morgan 4) Sutton and Boveri.
by YyRr?
79. X-body is found in _______% of sperms.
1) 2 2) 4
1) 25 2) 50
3) 75 4) 90 3) 6 4) 8

80. Match the items of column-I with those in 85. Sex determination in most of insects is :
column- II
1) XO type, male heterogamety
Column-I Column-II
2) XY type, male heterogamety
A) Male heterogamety 1. Grasshopper
3) ZW type, female heterogamety
B) Female heterogamety 2. Cancer cells
C) Chromosomal 3. Birds 4) ZZ type, type, female heterogamety.

aberrations 86. In birds, male possess -


D) Point aberrations 4. Sickle cell anemia 1) 1 chromosome less than that of female.
1) A-1, B-3, C-4, D-2
2) 1 Chromosome more than that of female
2) A-1, B-3, C-2, D-4
3) Chromosomes equal to that of female.
3) A-3, B-1, C-2, D-4
4) 1 set of chromosomes less than that of female.
4) A-3, B-1, C-4, D-2

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 8


87. Among the following genetic disorders, 92. Trisomy of chromosome number 21 is

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
identify which are Mendelian disorders - characterized by all of following except -
1) Partially open mouth
(i) Sickle cell anemia (ii) Thalessemia
2) Short stature
(iii) Down's syndrome (iv) Haemophilia
3) Mental retardation
(v) Malaria (vi) Phenylketonuria 4) Large round head.
1) Two 2) Three 93. Mendel has worked on garden pea. Few traits
chosen by Mendel are shown in the diagram.
3) Four 4) five Select the correct statement.
88. Incorrect about Mendelian disorders -
1) Can be dominant or recessive
2) These can be traced with pedigree analysis
3) These are present on autosomes only
4) Mutation occur in single gene usually.
89. Select the incorrect statement -
1) P is representing the axial flower position and
1) Male child may become haemophilic if his
is a recessive trait
mother is a carrier for haemophilia.
2) Q is representing the terminal flower position
2) Sickle cell anemia is a classical example of and is a recessive trait
chromosomal mutation. 3) R is representing the round seed shape and is
a recessive trait
3) Gynaecomastia develops in Klinefelter's
syndrome. 4) S is representing the wrinkled pod shape and
is a recessive trait.
4) Trisomy of chromosome number 21 results
94. Rudimentary ovaries and lack of feminine
in Down's syndrome. characters are observed in female with -
90. Identify the correct statement regarding the 1) Turner's syndrome
chromosomal aberrations - 2) Klinefelter's syndrome
1) Aneuploidy results from non-disjunction of 3) Cystic fibrosis
chromosomes. 4) Thalessemia.

2) Long and furrowed tongue is observed in 95. Under __1__ oxygen tension, RBC changes its
shape to an elongated sickle like structure due
patients of Down's syndrome.
to __2__ of the affected __3__ molecule.
3) Polyploidy is commonly seen in animals. 1) 1 - High, 2 - Polymerization, 3 - Myoglobin
4) Female becomes sterile in monosomy of sex 2) 1 - High, 2 - Condensation, 3 - Haemoglobin
chromosome. 3) 1 - Low, 2 - Condensation, 3 - Myoglobin
91. 44 + XXY condition is found in - 4) 1 - Low, 2 - Polymerization, 3 - Haemoglobin
96. Sickle cell anemia is -
1) Klinefelter's syndrome
1) Autosomal recessive disease
2) Down's syndrome 2) Autosomal dominant disease
3) Turner's syndrome 3) Sex-linked recessive disease
4) Haemophilia. 4) Sex-linked dominant disease.

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 9


97. An idiogram is shown. Observe it and 100. In sickle cell anemia, __1__ is substituted by

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
identify the related disease. __2__ at __3__ position of p-globulin chain.
1) 1 - Glutamic acid, 2 - Phenylalanine, 3 - 3rd
2) 1 - Glutamic acid, 2 - Valine, 3 - 3rd
3) 1 - Valine, 2 - Glutamic acid, 3 - 6th
4) 1 - Glutamic acid, 2 - Valine, 3 - 6th
101. Queen Victoria was carrier of -
1) Haemophilia 2) Sickle cell anemia
3) Phenylketonuria 4) Alkaptonuria.
1) Turner's syndrome 102. If after __1__, cytokinesis fails, it leads to __2__
2) Sickle cell anemia which is commonly seen in __3__

3) Muscular dystrophy 1) 1 - Telophase, 2 - Aneuploidy, 3 - Plants


2) 1 - Anaphase, 2 - Polyploidy, 3 - Animals
4) Down's syndrome.
3) 1 - Telophase, 2 - Polyploidy, 3 - Plants
98. A and B are pictures of two individuals
showing symptoms of two different diseases. 4) 1 - Anaphase, 2 - Aneuploidy, 3 - Animals
Identify the disease on the basis of given 103. If whole set of chromosomes is doubled it is
symptoms. termed as __________
1) Polyploidy 2) Aneuploidy
3) Blending 4) Mendelian disorder.
104. Taking flower colour as acharacter, following
cross was done. Observe the cross and its
results. Identify the plant in which such cross
is possible?

1) A - Down's syndrome, B - Turner's Syndrome


2) A - Klinefelter syndrome, B - Turner's
syndrome
3) A - Muscular dystrophy, B - Klinefelter's
syndrome
4) A - Turner's syndrome, B - Down's syndrome
99. Which of the following pair is of autosomal
recessive disorders?
1) Phenylketonuria and Sickle cell anemia.
2) Colourblindness and Turner's syndrome.
3) Down's syndrome and Turner's syndrome. 1) Garden pea 2) Snapdragon
4) Down's syndrome and Cystic fibrosis. 3) Touch me not 4) Maize

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 10


105. Few traits of pea plant are shown in the 109. Three diagrams are shown below (A, B, C)

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
diagram as chosen by Mendel. How many of which are three stages of meiosis and germ
them are recessive in nature? cell formation in a cell. Identify the correct
sequence of occurrence.

1) None 2) One
3) Two 4) Three 1) A  B  C 2) A  C  B
106. A homozygous recessive white flowered pea 3) B  C  A 4) C  A  B
plant was crossed with another pea plant with
110. Fully grown male and female Drosophila are
unknown genotype and phenotype to obtain
shown in figures (P and Q). Select the correct
following result. What was thaphenotype and
statement.
genotype of that pea plant?

1) P is male Drosophila with sex chromosome


XY.
2) P is female Drosophila with sex chromosome
XX.
1) Violet, homozygous 3) Q is male Drosophila with sex chromosome
ZW.
2) Violet, heterozygous
4) Q is female Drosophila with sex chromosome
3) White, homozygous
ZZ.
4) White, heterozygous
111. Fully grown Drosophila (male and female)
107. Aa is an allelic arrangement in a gene. Allele and chicken (male and female) are shown in
A produces a normal enzyme and is dominant diagrams. Tick the one in which sex
while allele a is recessive and is suppose to chromosome is represented as ZW.
produce -
1) Less efficient enzyme
2) No enzyme
1) 2)
3) Non-functional enzyme
4) Both (2) and (3)
108. Law of segregation nullifies the phenomenon
of -
1) Mutation 2) Blending inheritance 3) 4)
3) Crossing over 4) Co-dominance.
Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 11
112. Sex chromosome is an organism is shown 118. Parents with a affected male child can be

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
below. Which can be the possible organism? represented as following in pedigree analysis -

1) 2)

3) 4)

119. Identify the incorrect match -


1) Male chicken 2) Female chicken
1)
3) Male Drosophila 4) Female Drosophila.
113. Which of the following symbol indicates 2)
'affected individual' in pedigree analysis?

1) 2)
3)

3) 4)
4)
114. In Mendel's experiments, what is expected in
Filial1 generation if 2 true breeding purelines 120. Which of the following disease can be
for flower position are crossed? represented by the given pedigree analysis?
1) All terminal
2) All axial
3) Terminal : Axial = 3 : 1
4) Terminal : Axial = 1 : 3
115. During his experiments, Mendel crossed pea
1) Myotonic dystrophy
plants with green seeds (pureline) and yellow
2) Sickle cell anemia
(pureline). In F1 progeny, plants will produce
1) All green seeds 3) Testis determining factor
2) All yellow seeds 4) Colourblindness.
3) Green seeds : Yellow seeds = 3 : 1 121. Select the incorrect statement -
1) Segregation of chromosomes occur at
4) Yellow seeds : Green seeds = 3 : 1
anaphase-I.
116. Mendel crossed homozygous tall pea plant
with dwarf pea plant. What will be the 2) Drosophila can produce large number of
progeny by a single mating.
expected F1 progeny?
3) Karl Correns was one of the rediscoverers of
1) Tall : Dwarf =3 : 1 2) Tall : Dwarf =2 : 1
the Mendelian work.
3) All tall 4) All Dwarf
4) Chromosomal theory of inheritance was
117. What is the meaning of following symbol in
unable to explain Mendel's laws.
pedigree analysis?
122. Which of the following statement is not in
accordance with chromosomal theory of
inheritance?
1) Chromosomes segregate independently
1) Mating during formation of gametes
2) 5 unaffected offspring 2) Chromosomes occur in pair
3) Affected male 3) Chromosomes are Mendel's factors
4) Consanguineous mating. 4) Chromosomes possess genetic material.
Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 12
123. Tendency of genes to remain together during 127. A relevant portion of B-chain of haemoglobin

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
the formation of gametes is : is shown in the diagram. Identify the type of
Hb.
1) Linkage 2) Inheritance
3) Pleiotropy 4) Test cross.
124. A photograph of RBCs is shown. Identify the
disease with one of its feature.
1) Hb-A peptide 2) Hb-S peptide
3) Hb-A2 peptide 4) Hb-F peptide.
128. Identify the disease whose sign and symptoms
are shown in the given diagram.

1) Bone marrow failure, reduced blood cell count.


2) Thalessemia, Fe2+ deficiency in diet.
3) Haemophilia, delayed clotting of blood.
4) Sickle cell anemia, early haemolysis of RBCs.
125. Amino acid sequence of a relevant portion of
B - haemoglobin chain is shown in diagram.
1) Patau's Syndrome
Normally __P__ amino acid in present at 6 th
position which is replaced by __Q__ amino 2) Down's Syndrome
acid in sickle cell anemia. 3) Edward's Syndrome
4) Klinefelter's Syndrome
129. Which of the following term defines the
morphology of trait?
1) Phenotype 2) Genotype
3) Punnett square 4) True breeding line
130. T = Tallness (dominant trait)
t = Dwarfness (recessive trait)
Step 1 : TT × tt was done to obtain F1 progeny.
P Q
Step 2 : F1 progeny was self fertilized to obtain
1) Glutamine Valine F2 progeny. Select the incorrect result -
2) Lysine Glycine 1) Phenotypic ratio (F1 progeny) = 3 : 1 (Tall :
3) Valine Glutamine Dwarf)
4) Glycine Valine 2) Genotypic Ratio (F1 Progeny) = All Tt.
126. In normal haemoglobin, _______ amino acid 3) Phenotypic ratio (F2 progeny) = 3 : 1 (Tall :
is present at ______ position. Dwarf)
1) Glycine, 2nd 2) Glycine, 6th 4) Genotypic Ratio (F2 Progeny) = 1 : 2 : 1 (TT :
3) Proline, 3 rd
4) Glutamine, 6 th Tt: tt).

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 13


131. Read the following steps and arrange them 137. Select the mismatch -

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
in correct sequence of occurrence. 1) Gene mapping - Paul Berg
P - Entry of an allele in gamete. 2) X-body - Henking
Q - Fertilization. 3) Chromosomal theory of inheritance - Sutton
R - Segregation of alleles. and Boveri

S - Formation of recombinants. 4) Worked on Tiny fruitfly - T.H. Morgan.

1) P  Q  S  R 2) P  R  Q  S 138. Select the set of incorrect statements -

3) R  P  Q  S 4) R  P  S  Q A. Life span of Tiny fruitfly is 2 months

132. Select a recessive trait in pea chosen by B. Tshermak was one of the rediscoveries of
Mendel? (NCERT Correction) Mendelian work.

1) Violet flower colour C. Chromosomal theory of inheritance was


experimentally proved by Sutton and
2) Yellow-seed colour
Boveri
3) Constricted pod shape
1) A only 2) A, c
4) None of the above.
3) B, C 4) A, B, C
133. Select the shape of seed in pea chosen by
Read the Assertion and Reason carefully to
Mendel that represents the dominant trait?
mark the correct option out of the options
(NCERT Correction) given below
1) Round 2) Inflated 1) If both Assertion and Reason are true and the
Reason is a correct explanation of the Assertion
3) Wrinkled 4) Constricted
2) If both Assertion and Reason are true but the
134. Mendel succeeded in his experiments on pea
Reason is not a correct explanation of the
plant because of following reasons except one
Assertion.
1) He has done statistical analysis
3) If Assertion is true but the Reason is false.
2) He has taken large sampling size
4) If both the Assertion and Reason are false.
3) He believed in blending inheritance
139. Assertion: Haemophilia never occurs in women.
4) He has taken different characters to generalize
Reason: Gene for haemophilia is located on Y
the results.
chromosome.
135. Allelic arrangement in the gene is termed as-
140. Assertion: Holandric genes are found on Y
1) Phenotype 2) Genotype chromosome.
3) F1 generation 4) Punnett square Reason: Inheritance of Holandric genes are
136. If single character taken in consideration always from father to son.
during cross, it is termed as - 141. Assertion: The genetic complement of an
1) Test cross 2) Monohybrid cross organism is called genotype.

3) Polyhybrid cross 4) Back cross Reason: Genotype determines heredi tary


characters of an organism.
Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 14
142. Assertion: Phenylketonuria is a recessive 149. Assertion: Number of chromosomes in one

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
hereditary disease caused by body's failure to genome is equal to number of linkage group.
oxidise an amino acid phendylanine to tryrosine, Reason: linkage group give important information
because of a defective enzyme. about the location of genes in the chromosomes.

Reason: It results the presence of phenylalanine 150. Assertion: Hybrids are the offsprings of parents
amino acid in urine. with at least one or more traits.
Reason: Mendel had crossed pure parents with
143. Assertion: Clones are produced by sexual
at least one contrasting trait and obtained F 1
reproduction and same sexual process.
progeny and called it monohybrid cross.
Reason: These are prepared by group of cells 151. Assertion: Diff erent alleles o ccur due to
descended from many cells or by inbreeding of mutation which are more stable and inherited
a heterozygous line. from parent to progeny.

144. Assertion: In human, the gamete contributed Reason: One allele may be modified into
by the male determines whether the child different allele by crossing over.
produced will be male or female. 152. Assertion: Haploid plant is used to from diploid
homozygous plant.
Reason: Sex in human is a polygenic trait
Reason: In gymnosperms, endosperm is formed
depending upon a cumulative effect of some
by triple fusion.
genes on X-chromosome and some on Y-
chromosome. PREVIOUS YEAR QUESTIONS
153. Select the correct statement from the ones
145. Assertion: Gene expression is a molecular
given below with respect to dihybrid cross.
mechanism by which a gene expresses a phenotype.
[AIPMT (Prelims)-2010]
Reason: Structural genes are controlled by
1) Genes far apart on the same chromosome
control genes.
show very few recombinations.
146. Assertion: Persons suffering from haemophilia 2) Genes loosely linked in the same chromosome
fail to produce blood clotting factor VIII. show similar recombinations as the tightly
linked ones.
Reason: Prothrombin producing platelets in
such perso ns are found i n very low 3) Tightly linked genes on the same chromosome
concentration. show very few recombinations.
4) Tightly linked genes on the same chromosome
147. Assertion: In a pedigree analysis, 5 respresents
show higher recombinations.
five unaffected offsprings.
154. Which one of the following cannot be
Reason: In a pedigree analysis, the offsprings are explained on the basis of Mendel's Law of
numbered with Arabic numerals (1, 2, 3.....) and Dominance? [AIPMT (Prelims)-2010]
a generation is numbered with roman numerals 1) Out of one pair of factors, one is dominant
(I, II, III....). and the other recessive
2) Alleles do' not show any blending and both
148. Assertion: XX-YY type of sex determination
the characters recover as such in F2 generation
mechanism is an example of male heterogametly.
3) Factors occurs in pairs
Reason: In bird, Male heterogamety is seen as 4) Discrete unit controlling a particular character
males produce two different types of gametes. is called a factor

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 15


155. Which one of the following symbols and its 160. Study the pedigree chart of certain family

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
representation used in human pedigree given here and select the correct conclusion.
analysis is correct? [AIPMT (Prelims)-2010] [AIPMT (Mains)-2010]

1) = unaffected male

2) = unaffected female
1) The female parent is heterozygous.
2) The parents could not have had a normal
3) = male affected daughter for this character.
3) The trait under study could not be colour
blindness.
4) = mating between relatives 4) The male parent is homozygous dominant.
161. The fruit fly Drosophila melanogaster was
156. ABO blood groups in humans are controlled
found to be very suitable for experimental
by the gene I. It has three alleles - IA, IB and i.
verification of chromosome theory of
Since there are three different alleles, six inheritance by Morgan and his colleagues
different genotypes are possible. How many because [AIPMT (Mains)-2010]
phenotypes can occur?
1) It reproduce parthenogenetically.
[AIPMT (Prelims)-2010]
2) Smaller female is easily distinguishable from
1) Three 2) One large male.
3) Four 4) Two 3) A single mating produces two young flies.
157. The genotype of a plant showijig the 4) It completes life cycle in about two weeks.
dominant phenotype can be determined by
162. ABO blood grouping is controlled by gene I
[AIPMT (Prelims)-2010] which has three alleles and show co-
dominance. There are six genotypes. How
1) Black cross 2) Test cross
many phenotypes in all are possible?
3) Dihybrid cross 4) Pedigree analysis
[AIPMT (Mains)-2010]
158. In Antirrhinum, two plants with pink flowers
1) Six 2) Three
were hybridised. The F1 plants produced red.
Pink and white flowers in ratio of 1 : 2 : 1. 3) Four 4) Five
What could be genotype of the parent plants? 163. Which one of the following conditions
RR is red, rr is white [AIPMT (Mains)-2010] correctly describes the manner of determining
the sex in the given example?
1) rr 2) Rr
[AIPMT (Prelims)-2011]
3) RR 4) RRrr
1) XO co ndition in Turner's syndrome
159. A cross in which an organism showing a
determines female sex.
dominant phenotype is crossed with the
recessive parent in order to know its genotype 2) Homozygous XX produce male in Drosophila.
is called [AIPMT (Mains)-2010] 3) Homozygous ZZ determine female sex in
1) Monohybrid cross 2) Back cross birds.

3) Test cross 4) Dihybrid cross 4) XO determines male sex in Grasshopper.

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 16


164. When two unrelated individuals or lines are 169. A test cross is carried out to

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
crossed, the performance of F1 hybrid is often [AIPMT (Mains)-2012]
superior of both its parents. This phenomenon
is called [AIPMT (Prelims)-2011] 1) Determine the genotype of a plant at F2
1) Metamorphosis 2) Heterosis 2) Predict whether two traits are linked
3) Transformation 4) Splicing
3) Assess the number of alleles of a gene
165. Test cross in plants or in Drosophila involves
crossing [AIPMT (Mains)-2011] 4) Determine whether two species or varieties
1) The F 1 hybrid wi th a double recessive will breed successfully.
genotype
170. If both parents are carriers for thalassemia,
2) Between two genotypes with dominant trait
which is an autosomal recessive disorder,
3) Between two genotypes with recessive trait
what are the chances of pregnancy resulting
4) Between two F1 hybrids in an affected child? [NEET-2013]
166. A normal visioned man whose father was
colour-blind, marries a woman whose father 1) 25% 2) 100%
was also colour-blind. They have their first 3) No chance 4) 50%.
child as a daughter. What are chances that
their child would be colour-blind? 171. Which Mendelian idea is depicted by a cross
[AIPMT (Prelims)-2012] in which the F1 generation resembles both the
1) 0% 2) 25 % parents? [NEET-2013]
3) 50% 4) 100% 1) Inheritance of one gene
167. F2 generation in a Mendelian cross showed
that both genotypic and phenotypic ratios are 2) Co-dominance
same as 1 : 2 : 1. It represents a case of 3) Incomplete dominance
[AIPMT (Prelims)-2012]
4) Law of dominance
1) Co-dominance
2) Dihybrid cross 172. Which of the following cannot be detected in
3) Monohybrid cross with complete dominance a developing foetus by amniocentesis?
4) Mono hybrid cross with incomplete [NEET-2013]
dominance
1) Down syndrome
168. Represented below is the inheritance pattern
of a certain ty of traits in humans. Which one 2) Jaundice
of the following conditi could be an example
3) Klinefelter syndrome
of this pattern? [AIPMT (Mains)-2012]
4) Sex of the foetus

173. The incorrect statement with regard to


Haemophilia is [NEET-2013]

1) It is a dominant disease.

2) A single protein involved in the clotting of


blood is affected.

3) It is a sex-linked disease.
1) Phenylketonuria 2) Sickle cell anaemia
3) Haemophilia 4) Thalassemia 4) It is a recessive disease.

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 17


174. If two persons with 'AB' blood group marry 179. A colour blind man marries a normal woman

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
and have sufficiently large number of (without any history of colour blindness in
children, these children could classified as 'A' her family). What is the probability that their
blood group: 'AB' blood group : 'B' blood group grandsons will be colour blind?[AIPMT-2015]
in 1 : 2 : 1 ratio. Modern technique of protein; 1) 0.25 2) 0.5
ectrophoresis reveals presence of both 'A' and 3) 1 4) Nil
'B' type rroteins in ' AB' blood group 180. The term "linkage" was coined by
individuals. This is an example [NEET-2013] [AIPMT-2015]
1) Partial dominance 1) T. Boveri 2) G. Mendel
2) Complete dominance 3) W. Sutton 4) T. H. Morgan
181. A pleiotropic gene: [AIPMT-2015]
3) Codominance
1) Controls multiple traits in an individual.
4) Incomplete dominance 2) Is expressed only in primitive plants.
175. Which of the following statements is not true 3) Is gene evolved during Pliocene
of two genes that show 50% recombination 4) Controls a trait only in combination with
frequency? [NEET-2013] another gene
1) The genes show independent assortment. 182. In his classic experiments on pea plants,
2) If the genes are present on the same Mendel did not use [AIPMT-2015]
chromosome, they undergo more than one 1) Pod length 2) Seed shape
crossovers in every meiosis. 3) Flower position 4) Seed colour
3) The genes may be on different chromosomes. 183. In the following human pedigree, the filled
4) The genes are tightly linked. symbols represent the affected individuals.
Identify the type of given pedigree.
176. Fruit colour in squash is an example of [AIPMT-2015]
[AIPMT-2014]
1) Inhibitory genes
2) Recessive epistasis
3) Dominant epistasis
4) Complementary genes
177. A man whose father was colour blind marries
a woman who had a colour blind mother and
normal father. What percentage of male
children of this couple will be colour blind?
[AIPMT-2014] 1) X-linked recessive 2) Autosomal recessive
1) 75% 2) 25% 3) X-linked dominant 4) Autosomal dominant
3) 0% 4) 50% 184. A gene showing codominance has
178. A human female with Turner's syndrome [AIPMT-2015]
[AIPMT-2014] 1) Alleles tightly linked on the same chromosome
1) is able to produce children with normal
2) Alleles that are recessive to each other
husband
2) has 45 chromosomes with XO 3) Both alleles independently expressed in the
heterozygote
3) has one additional X chromosome
4) One allele dominant on the other
4) exhibits male characters

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 18


185. A man with blood group 'A' marries a women 191. Pick out the correct statements.

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
with blood group 'B'. What are all the possible [NEET-2016 Phase I]
blood groups of their off springs?
[Re-AIPMT-2015] a) Haemophilia is a sex-linked recessive
disease
1) A, B, AB and O 2) Oonly
b) Down's syndrome is due to aneuploidy
3) A and B only 4) A, Band AB only
c) Phenylketonuria is an autosomal recessive
186. How many pairs of contrasting characters in
gene disorder
pea plants were studied by Mendel in his
experiments? [Re-AIPMT-2015] d) Sickle cell anaemia is an X-linked recessive
1) Eight 2) Seven gene disorder

3) Five 4) Six 1) (a), (c) and (d) are correct


187. Multiple alleles are present 2) (a), (b) and (c) are correct
[Re-AIPMT-2015]
3) (a) and (d) are correct
1) At the same locus of the chromosome
4) (b) and (d) are correct
2) On non-sister chromatids
192. A tall true breeding garden pea plant is
3) On different chromosomes
crossed with a dwarf true breeding garden
4) At different loci on the same chromosome pea plant. When the F1 plants were selfed, the
188. Which of the most common mechanism of resulting genotypes were in the ratio of
genetic variation in the population of a [NEET-2016 Phase I]
sexually-reproductive organism?
[Re-AIPMT-2015] 1) 3 : 1 : : Tall : Dwarf

1) Genetic drift 2) 3 : 1 : : Dwarf : Tall

2) Recombination 3) 1 : 2 : 1 : : Tall homozygous : Tall heterozygous


3) Transduction : Dwarf

4) Chromosomal aberrations 4) 1 : 2 : 1 : : Tall heterozygous : Tall homozygous


: Dwarf
189. Alleles are [Re-AIPMT-2015]
193. In a testcross involving F1 dihybrid flies, more
1) Different molecular forms of a gene
parental-type offspring were produced than
2) Heterozygotes the recombinant-type offspring. This indicates
3) Different phenotype [NEET-2016 Phase I]
4) True breeding homozygotes' 1) The two genes are linked and present on the
190. An abnormal hnman body with 'XXX' sex same chromosome.
chromosomes was born due to
2) Both of the characters are controlled by more
[Re-AIPMT-2015] than one gene.
1) Fusion of two ova and one sperm 3) The two genes are l-ocated on two different
2) Fusion of two sperms and one ovum chromosomes

3) Formation of abnormal sperms in the father 4) Chromosomes failed to separate during


4) Formation of abnormal ova in the mpther meiosis.

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 19


194. Match the terms in Column-I with their 197. A true breeding plant is

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
description in Column-II, and choose the [NEET-2016 Phase II]
correct option. [NEET-2016 Phase I]
1) Near homozygous and produces offspring of
Column I Column II its own kind

a) Dominance i. Many genes govern 2) Always homozygous recessive in its genetic


a single character constitution

b) Co-dominance ii. In a heterozygous 3) One that is able to breed on its own


organism only one 4) Produced due to cross-pollination among
allele expresses itself unrelated plants
c) Pleiotropy iii. In a heterozygous 198. If a colour-blind man marries a woman who
organism both is homozygous for normal colour vision, the
alleles express probability of their son being colour-blind is
themselves fully [NEET-2016 Phase II]
d) Polygenic iv. A single gene 1) 0.75 2) 1
inheritance influences many
3) 0 4) 0.3
characters
199. Thalassemia and sickle cell anaemia are
a b c d
caused due to problem in globin molecule
1) iv i ii iii synthesis. Select the correct statement.
2) iv iii i ii [NEET-2017]
3) ii i iv iii 1) Both are due to a quantitative defect in globin
chain synthesis.
4) ii iii iv i
2) Thalassemia is due to less synthesis of globin
195. Which of the following most appropriately
molecules
describes haemophilia? [NEET-2016 Phase I]
3) Sickle cell anaemia is due to a quantitative
1) Chromosomal disorder
problem of globin molecules.
2) Dominant gene disorder
4) Both are due to a qualitative defect in globin
3) Recessive gene disorder chain synthesis.
4) X- linked recessive gene disorder 200. The genotypes of a Husband and Wife are IA
IB and I Ai Among the blood types of their
196. The mechanism that causes a gene to move
children, how many different genotypes and
from one linkage group to another is called
phenotypes are possible? [NEET-2017]
[NEET-2016 Phase II]
1) 3 genotypes ; 4 phenotypes
1) Translocation
2) 4 genotypes; 3 phenotypes
2) Crossing-over
3) 4 genotypes ; 4 phenotypes
3) Inversion
4) 3 genotypes; 3 phenotypes
4) Duplication

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 20


201. A disease caused by an autosomal primary 207. Which of the following characteristics

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
non-disjunction is [NEET-2017] represent 'Inheritance of blood groups' in
1) Klinefelter's Syndrome humans? [NEET-2018]

2) Turner's Syndrome a. Dominance b. Co-dominance

3) Sickle Cell Anaemia c. Multiple allele d. Incomplete dominance

4) Down's Syndrome e. Polygenic inheritance

202. Among the following characters, which one 1) b, c and e 2) a, b and c


was not considered by Mendel in his 3) b, d and e 4) a, c and e
experiments on pea? [NEET-2017]
208. A woman has an X-linked condition on one
1) Trichomes - Glandular or non-glandular of her X chromosomes. This chromosome can
2) Seed - Green or Yellow be inherited by [NEET-2018]

3) Pod - Inflated or Constricted 1) Only daughters

4) Stem - Tall or Dwarf 2) Only sons

203. Which one from those given below is the 3) Only grandchildren
period for Mendel' s hybridization 4) Both sons and daughters
experiments? [NEET-2017]
209. In Antirrhinum (Snapdragon), a red flower
1) 1840 - 1850 2) 1857 - 1869 was crossed with a white flower and in F 1
3) 1870 - 1877 4) 1856 - 1863 generation pink flowers were obtained. "Alien
pink flowers were selfed, the F 2 generation
204. Select the correct statement. [NEET-2018]
showed white, red and pink flowers. Choose
1) Franklin Stahl coined the term linkage". the incorrect statement from the following.
2) Punnett square was developed by a British [NEET-2019]
scientist.
1) Pink colour in F 1 is due to incomplete
3) Spliceosomes take part in translation. dominance.
4) Transduction was discovered by S. Altman. 2) Ratio of F2 is 1/4 (Red) : 2/4(Pink) : 1/4 (White).
205. Which of the following pairs is wrongly 3) Law of Segregation does not apply in this
matched? [NEET-2018] experiment.
1) Starch synthesis in pea : Multiple alleles 4) This experiment does not follow the Principle
2) ABO blood grouping : Co-dominance of Dominance.

3) XO type sex determination : Grasshopper 210. What is the genetic disorder in which an
individual has an overall masculine
4) T. H. Morgan : Linkage development, gynaecomastia, and is sterile?
206. Select the correct match. [NEET-2018] [NEET-2019]
1) Ribozyme—Nucleic acid
1) Klinefelter's syndrome
2) F2 × Recessive parent—Dihybrid cross 2) Edward syndrome
3) T. H. Morgan—Transduction 3) Down's syndrome
4) G. Mendel—Transformation 4) Turner's syndrome.
Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 21
RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
211. Select the incorrect statement. [NEET-2019] 215. In a marriage between male with blood group
1) In male grasshoppers, 50% of sperms have A and female with blood group B, the progeny
no sex-chromosome. had either blood group AB or B. What could
2) In domesticated fowls, sex of progeny be the possible genotype of parents?
depends on the type of sperm rather than egg. [NEET(Odisha)-2019]
3) Human males have one of their sex- 1) IAi (Male): IBIB (Female)
chromosome much shorter than the other. 2) IAIA (Male): IBIB (Female)
4) Male fruit fly is heterogametic. 3) IAIA (Male): IBi (Female)
212. What map unit (Centimorgan) is adopted in 4) IAi (Male) : IBi (Female).
the construction of genetic maps? [NEET-2019]
216. In which genetic condition, each cell in the
1) A unit of distance between two expressed affected person, has three sex chromosomes
genes, representing 10% cross over. XXY? [NEET(Odisha)-2019]
2) A unit of distance between genes on 1) Thalassemia
chromosomes representing 1% cross over.
2) Klinefelter's Syndrome
3) A unit of distance between genes on
3) Phenylketonuria
chromosomes, representing 50% cross over.
4) Turner's Syndrome
4) A unit of distance between two expressed
ggnes, representing 100%.cross over. 217. The production of gametes by the parents, the
formation of zygotes, the F1 and F2 plants, can
213. The frequency of recombination between gene
be understood using [NEET(Odisha)-2019]
pairs on the; same chromosome as a measure
of the distance between genes was explained 1) Pie diagram 2) A pyramid diagram
by [NEET-2019] 3) Punnet square 4) Venn diagram
1) Gregor J. Mendel 2) Alfred Sturtevant 218. Identify the wrong statement with reference
3) Sutton Boveri 4) T. H. Morgan to the gene I that controls ABO blood groups.
214. Match the items of column I and with column [NEET-2020]
II 1) The gene (I) has three alleles.
Column I Column II 2) A person will have only two of the three alleles.
(a) XX-XO method of i. Turner’s syndrome 3) When I A and I B are present together, they
sex determination express same type of sugar.
(b) XX-XY method of ii. Female heterogametic 4) Allele 'i' does not produce any sugar.
sex determination 219. Experimental verification of the chromosomal
theory of inheritance was done by
(c) Karyotype-45 iii. Grasshopper
[NEET-2020]
(d) ZW-ZZ method of iv. Female homogametic
1) Mendel 2) Sutton
sex determination
3) Boveri 4) Morgan
Select the correct option from the following :
[NEET(Odisha)-2019] 220. Select the correct match. [NEET - 2020]

a b c d 1) Haemophilia-Y linked
2) Phenylketonuria-Autosomal dominant trait
1) ii iv i iii
3) Sickle cell anaemia-Autosomal recessive trait,
2) i iv ii iii
chromosome-11
3) iii iv i ii
4) Thalassemia-X linked
4) iv ii i iii

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 22


221. How many true breeding pea plant varieties 226. Which of the following occurs due to the

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
did Mendel select as pairs, which were similar presence of autosome linked dominant trait?
except in one character with contrasting
[NEET - 2022]
traits? [NEET - 2020]
1) Sickle cell anaemia
1) 4 2) 2
3) 14 4) 8 2) Myotonic dystrophy

222. The production of gametes by the parents, 3) Haemophilia


formation of zygotes, the F1 and F2 plants, can 4) Thalessemia
be understood from a diagram called
[NEET - 2021] 227. Given below are two statements: one is
labelled as [NEET - 2022]
1) Punch square 2) Punnett square
Assertion (A) and the other is labelled as Reason
3) Net square 4) Bullet square
(R).
223. In a cross between a male and female, both
Assertion (A) : Mendel's law of Independent
heterozygous for sickle cell anaemia gene,
assortment does not hold good for the genes that
what percentage of the progeny will be
are located closely on the same chromosome.
diseased? [NEET - 2021]
1) 75% 2) 25% Reason (R) : Closely located genes assort
independently.
3) 100% 4) 50%
In the light of the above statements, choose the
224. Given below are two statements:
correct arfewer from the options given below:
[NEET - 2022] 1) Both (A) and (R) are correct and (R) is the
Statement I : Mendel studied seven pairs of correct explanation of (A)
contrasting traits in pea plants and proposed the
2) Both (A) and (R) are correct but (R) is not the
Laws of Inheritance
correct explanation of (A)
Statement II : Seven characters examined by
3) (A) is correct bu t (R) is not correct
Mendel in his experiment on pea plants were
seed shape and colour, flower colour, pod shape 4) (A) is not correct but (R) is correct
and colour, flower position and stem height
228. The recombination frequency between the
In the light of the above statements, choose the genes a & c is 5%, b & c is 15%, b & d is 9%, a
correct answer from the options given below: & b is 20%, c & d is 24% and a & d is 29%.
1) Both Statement I and Statement II are correct What will be the sequence of these genes on a
linear chromosome? [NEET - 2022]
2) Both Statement I and Statement II are
incorrect 1) a, d, b, c 2) d, b, a, c
3) Statement I is correct but Statement II is 3) a, b, c, d 4) a, c, b, d
incorrect 229. If a colour blind female marries a man whose
4) Statement I is incorrect but Statement II is mother was also colour blind, what are the
correct chances of her progency having colour
225. XO type of sex determination can be found blindness? [NEET - 2022]
in: 1) 25% 2) 50%
1) Drosophila 2) Birds
3) 75% 4) 100%
3) Grasshoppers 4) Monkeys

Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 23


Answer Key

RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC** RCC**
1 3 36 4 71 4 106 2 141 1 176 3 211 2
2 1 37 3 72 2 107 4 142 1 177 4 212 2
3 3 38 1 73 4 108 2 143 4 178 2 213 2
4 1 39 4 74 1 109 4 144 3 179 2 214 3
5 2 40 1 75 4 110 1 145 3 180 4 215 1
6 2 41 4 76 4 111 4 146 3 181 1 216 2
7 4 42 3 77 1 112 3 147 2 182 1 217 3
8 1 43 1 78 1 113 4 148 3 183 2 218 3
9 4 44 2 79 2 114 2 149 2 184 3 219 4
10 2 45 3 80 2 115 2 150 2 185 1 220 3
11 3 46 1 81 3 116 3 151 3 186 2 221 3
12 4 47 3 82 2 117 2 152 3 187 1 222 2
13 3 48 1 83 1 118 4 153 3 188 2 223 2
14 2 49 2 84 2 119 3 154 2 189 1 224 1
15 3 50 2 85 1 120 2 155 4 190 4 225 3
16 2 51 2 86 3 121 4 156 3 191 2 226 2
17 1 52 3 87 3 122 3 157 2 192 3 227 3
18 4 53 3 88 3 123 1 158 2 193 1 228 4
19 1 54 3 89 2 124 4 159 3 194 4 229 4
20 2 55 3 90 3 125 4 160 1 195 4
21 4 56 3 91 1 126 2 161 4 196 1
22 4 57 1 92 4 127 2 162 3 197 1
23 1 58 1 93 2 128 2 163 4 198 3
24 3 59 4 94 1 129 1 164 2 199 2
25 3 60 3 95 4 130 1 165 1 200 2
26 1 61 4 96 1 131 3 166 1 201 4
27 2 62 3 97 4 132 3 167 4 202 1
28 1 63 2 98 2 133 1 168 3 203 4
29 3 64 4 99 1 134 3 169 1 204 2
30 2 65 4 100 4 135 2 170 1 205 1
31 3 66 1 101 1 136 2 171 2 206 1
32 2 67 4 102 3 137 1 172 2 207 2
33 4 68 4 103 1 138 2 173 1 208 4
34 4 69 2 104 2 139 4 174 3 209 3
35 2 70 4 105 3 140 1 175 4 210 1
Prof.Motegaonkar S.R., M.Sc.Chem.,Gold Medalist, SET/NET-JRF,GATE, DRDO,TIFR Qualified Page: 24

You might also like