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Test Bank for Inquiry into Life 15th Edition

Test Bank for Inquiry into Life 15th Edition

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Chapter 07 - Cellular Respiration

Chapter 07
Cellular Respiration

Multiple Choice Questions

1. If the carbons from glucose were radioactively labeled, what molecule(s) would end up
with the label?
A. pyruvate
B. citric acid
C. carbon dioxide
D. carbon dioxide and citrate
E. pyruvate and carbon dioxide

The carbons from the glucose are converted into carbon dioxide in the preparatory reaction.
During the citric acid cycle the carbons are incorporated into citrate before being released
into the carbon dioxide.

Bloom's Level: 4. Analyze


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Cellular Respiration

2. Cellular respiration involves all of the following except


A. the breakdown of molecules.
B. the release of energy.
C. the synthesis of ATP.
D. breathing in and out.
E. the release of carbon dioxide.

Cellular respiration is the release of energy from molecules such as glucose accompanied by
the use of this energy to synthesize ATP molecules. It is an aerobic process that uses oxygen
and releases carbon dioxide. Do not confuse cellular respiration with the respiratory system.

Bloom's Level: 2. Understand


Learning Outcome: 07.01.01 Describe the overall equation for cellular respiration.
Section: 07.01
Topic: Cellular Respiration

7-1
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

3. Which of the following is a substrate of cellular respiration?


A. carbon dioxide
B. water
C. glucose
D. ATP
E. energy

Cellular respiration involves glucose + oxygen + ADP + P (substrates) going to carbon


dioxide + water + ATP (products).

Bloom's Level: 2. Understand


Learning Outcome: 07.01.01 Describe the overall equation for cellular respiration.
Section: 07.01
Topic: Cellular Respiration

4. Cellular respiration is an aerobic process. This means that it


A. uses energy.
B. produces energy.
C. requires carbon dioxide.
D. requires water.
E. requires oxygen.

An aerobic process is one that requires oxygen.

Bloom's Level: 2. Understand


Learning Outcome: 07.01.01 Describe the overall equation for cellular respiration.
Section: 07.01
Topic: Cellular Respiration

7-2
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

5. How efficient is the breakdown of one glucose via cellular respiration?


A. 100%
B. 58%
C. 39%
D. 20%
E. less than 10%

The breakdown of one glucose molecule results in 36-38 ATP or approximately 39% of the
potential energy within the glucose molecule. No reaction is 100% efficient.

Bloom's Level: 1. Remember


Learning Outcome: 07.01.01 Describe the overall equation for cellular respiration.
Section: 07.01
Topic: Cellular Respiration

6. The equation: C6H12O6 + 6O2 → 38 ATP + 6CO2 + 6H2O represents which cellular
process?
A. glycolysis
B. electron transport system
C. citric acid cycle
D. photosynthesis
E. cellular respiration

This is the formula for cellular respiration—the breakdown of glucose plus oxygen to form
carbon dioxide, water, and ATP.

Bloom's Level: 1. Remember


Learning Outcome: 07.01.01 Describe the overall equation for cellular respiration.
Section: 07.01
Topic: Cellular Respiration

7-3
Copyright © 2017 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 07 - Cellular Respiration

7. Which molecules are the products of aerobic respiration?


A. glucose and carbon dioxide
B. glucose and water
C. glucose and oxygen
D. lactate and carbon dioxide
E. carbon dioxide and water

Carbon dioxide and water (plus energy) are the products of aerobic respiration. Glucose plus
oxygen are the substrates.

Bloom's Level: 1. Remember


Learning Outcome: 07.01.01 Describe the overall equation for cellular respiration.
Section: 07.01
Topic: Cellular Respiration

8. Which molecules are the reactants or substrates for aerobic respiration?


A. glucose and carbon dioxide
B. lactate and oxygen
C. carbon dioxide and water
D. oxygen and glucose
E. glucose and water

Glucose and oxygen are the substrates for aerobic respiration. Carbon dioxide and water are
the products.

Bloom's Level: 2. Understand


Learning Outcome: 07.01.01 Describe the overall equation for cellular respiration.
Section: 07.01
Topic: Cellular Respiration

7-4
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

9. Why is ATP used as the energy molecule of the cell?


A. ATP is easy to synthesize within the cell.
B. ATP contains large amounts of energy so at least some of it can be used by the cell.
C. ATP contains just about the amount of energy required for most cellular reactions.
D. ATP is stored inside the cell where it is readily available whenever needed.
E. ATP can be broken down into carbon dioxide and water.

ATP contains just the right amount of energy necessary for most cellular reactions. It is not
stored within the cell or broken down into carbon dioxide and water. Although it is relatively
easy to synthesize, that does not make it a useful energy source.

Bloom's Level: 3. Apply


Learning Outcome: 07.01.01 Describe the overall equation for cellular respiration.
Section: 07.01
Topic: ATP Yield

10. What role does NAD+ play in cellular respiration?


A. It is an electron carrier.
B. It produces the ATP.
C. It is an enzyme.
D. It provides the oxygen.
E. It provides the energy.

NAD+ is a coenzyme which functions as an electron carrier.

Bloom's Level: 2. Understand


Learning Outcome: 07.01.02 Explain the role of electron carriers in respiration.
Section: 07.01
Topic: Cellular Respiration

7-5
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

True / False Questions

11. NADH and FADH2 bring electrons to the electron transport chain during cellular
respiration.
TRUE

Both NADH and FADH2 are electron carriers that bring electrons to the electron transport
chain during cellular respiration .

Bloom's Level: 1. Remember


Learning Outcome: 07.01.02 Explain the role of electron carriers in respiration.
Section: 07.01
Topic: Electron Transport Chain

Multiple Choice Questions

12. Which of the following does not describe the role of NAD+ in cellular respiration?
A. It accepts two electrons.
B. It is a coenzyme.
C. It helps to oxidize the substrate.
D. It is reduced.
E. It provides the energy for the reaction.

NAD+ does not provide energy for cellular respiration.

Bloom's Level: 1. Remember


Learning Outcome: 07.01.02 Explain the role of electron carriers in respiration.
Section: 07.01
Topic: Cellular Respiration

7-6
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

13. Which of the following reactions is NOT part of the cellular respiration pathway?
A. glycolysis
B. citric acid cycle
C. Calvin cycle
D. electron transport chain
E. preparatory reaction (prep)

Cellular respiration includes glycolysis, the preparatory reaction, the citric acid cycle, and the
electron transport chain. The Calvin cycle is part of photosynthesis.

Bloom's Level: 1. Remember


Learning Outcome: 07.01.03 Summarize the phases of cellular respiration and indicate where they occur in a cell.
Section: 07.01
Topic: Cellular Respiration

14. Why is cellular respiration organized into four phases?


A. So that the energy within the glucose molecule can be released in a stepwise fashion.
B. So that it can take place within different cells.
C. So that most of the energy can be released as body heat.
D. So that oxidation can occur without reduction.
E. So that the body can make energy from different substrates.

The four phases of cellular respiration allow the energy of the glucose molecule to be
released in a stepwise fashion and converted into ATP. If the breakdown occurred all at once,
most of the energy would be released as heat. The body can make ATP from different
substrates but that is not the reason for the phases.

Bloom's Level: 3. Apply


Learning Outcome: 07.01.03 Summarize the phases of cellular respiration and indicate where they occur in a cell.
Section: 07.01
Topic: Cellular Respiration

7-7
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

15. What is the correct order of phases in cellular respiration?


A. citric acid cycle, prep reaction, glycolysis, electron transport chain
B. electron transport chain, glycolysis, prep reaction, citric acid cycle
C. prep reaction, glycolysis, electron transport chain, citric acid cycle
D. glycolysis, prep reaction, citric acid cycle, electron transport chain
E. glycolysis, citric acid cycle, prep reaction, electron transport chain

The order of phases in cellular respiration is glycolysis, prep reaction, citric acid cycle, and
electron transport chain.

Bloom's Level: 1. Remember


Learning Outcome: 07.01.03 Summarize the phases of cellular respiration and indicate where they occur in a cell.
Section: 07.01
Topic: Cellular Respiration

16. Which of the following statements about glycolysis is true?


A. Glycolysis results in the release of carbon dioxide.
B. Glycolysis is a cyclical reaction.
C. Glycolysis is a reduction reaction where only glucose is reduced.
D. Glycolysis occurs twice per glucose molecule.
E. Glycolysis breaks glucose down to two pyruvate molecules.

Glycolysis is the breakdown of glucose to 2 pyruvate molecules. It is an oxidation reaction


that produces 2 ATP.

Bloom's Level: 4. Analyze


Learning Outcome: 07.02.01 Describe the location and inputs and outputs of glycolysis.
Section: 07.02
Topic: Glycolysis

7-8
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

17. Glycolysis is likely to have evolved before the citric acid cycle and electron transport
chain because
A. it has an older fossil record.
B. it is found in all living organisms.
C. it occurs inside the mitochondria.
D. the process is found in all primitive bacteria but lacking in many advanced organisms.
E. it produces more ATP than do the citric acid cycle and electron transport chain.

Since all organisms, even the most simple, use glycolysis, it most likely evolved first.
Glycolysis does not require oxygen and the environmental conditions when cells evolved
were anaerobic.

Bloom's Level: 5. Evaluate


Learning Outcome: 07.02.01 Describe the location and inputs and outputs of glycolysis.
Section: 07.02
Topic: Glycolysis

18. Where does glycolysis take place within the cell?


A. endoplasmic reticulum
B. nucleus
C. mitochondrial matrix
D. mitochondrial membrane
E. cytoplasm

Glycolysis takes place within the cytoplasm.

Bloom's Level: 1. Remember


Learning Outcome: 07.02.01 Describe the location and inputs and outputs of glycolysis.
Section: 07.02
Topic: Glycolysis

7-9
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

True / False Questions

19. The most efficient method to produce ATP in animal cells is by glycolysis.
FALSE

Glycolysis only results in a net of 2 ATP so it is not as efficient as the electron transport
chain.

Bloom's Level: 2. Understand


Learning Outcome: 07.02.01 Describe the location and inputs and outputs of glycolysis.
Section: 07.02
Topic: Glycolysis

20. Glycolysis is linked to the citric acid cycle when oxygen is not available.
FALSE

If no oxygen is available, the end product of glycolysis is fermented. Glycolysis is only


linked to the citric acid cycle when oxygen is available.

Bloom's Level: 2. Understand


Learning Outcome: 07.02.01 Describe the location and inputs and outputs of glycolysis.
Section: 07.02
Topic: Glycolysis

21. The final product of glycolysis is oxygen.


FALSE

The final product of glycolysis is pyruvate.

Bloom's Level: 1. Remember


Learning Outcome: 07.02.01 Describe the location and inputs and outputs of glycolysis.
Section: 07.02
Topic: Glycolysis

7-10
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

Multiple Choice Questions

22. Why are two ATP needed to begin glycolysis?


A. to activate the glucose
B. to donate electrons to NAD+
C. to compensate for the lack of oxygen
D. to accept electrons from glucose
E. to move the reaction into the mitochondria

The two ATPs are used to activate the glucose by adding two high energy phosphate bonds.

Bloom's Level: 3. Apply


Learning Outcome: 07.02.01 Describe the location and inputs and outputs of glycolysis.
Section: 07.02
Topic: Glycolysis

23. You have discovered an organism that lives inside the gastrointestinal tract and does not
contain a nucleus. Based on what you know of cellular respiration, how does it obtain its
energy?
A. photosynthesis
B. glycolysis
C. glycolysis and the citric acid cycle
D. photosynthesis and the citric acid cycle
E. glycolysis, the citric acid cycle, and the electron transport chain

All living organisms utilize glycolysis. Since it does not have a nucleus, it does not contain
mitochondria either, so it cannot use the citric acid cycle. Since it does not have access to
sunlight, it cannot photosynthesize.

Bloom's Level: 4. Analyze


Learning Outcome: 07.02.01 Describe the location and inputs and outputs of glycolysis.
Section: 07.02
Topic: Glycolysis

7-11
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

24. How many molecules are formed from the cleavage of glucose during the first step of
glycolysis? How many carbons are found in the resulting molecules?
A. 6 molecules, each with 2 carbons
B. 4 molecules, each with 3 carbons
C. 3 molecules, each with 4 carbons
D. 2 molecules, each with 3 carbons
E. 3 molecules, each with 2 carbons

Glucose is a 6-carbon molecule. It is broken into two molecules of glyceraldehyde 3-


phosphate, each with three carbons.

Bloom's Level: 2. Understand


Learning Outcome: 07.02.01 Describe the location and inputs and outputs of glycolysis.
Section: 07.02
Topic: Glycolysis

True / False Questions

25. There is a net gain of four ATPs as a result of glycolysis.


FALSE

Four ATPs are formed from glycolysis, however two ATPs are used to activate the glucose,
resulting in a net gain of only two ATP.

Bloom's Level: 2. Understand


Learning Outcome: 07.02.01 Describe the location and inputs and outputs of glycolysis.
Section: 07.02
Topic: Glycolysis

7-12
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

Multiple Choice Questions

26. Which of the following best defines substrate-level ATP synthesis?


A. An enzyme passes a high-energy phosphate to ADP, resulting in ATP.
B. ATP is used to activate glucose for glycolysis.
C. An exergonic reaction is used to drive the synthesis of ATP from ADP plus phosphate.
D. Oxidation of a substrate results in a high energy bond.
E. ATP is synthesized from adenosine plus three phosphates.

Substrate-level ATP synthesis results from the passing of a high-energy phosphate bond by
an enzyme to ADP. ATP is used to activate glucose and an exergonic reaction is used to drive
the synthesis of ATP, but those do not define substrate-level ATP synthesis.

Bloom's Level: 2. Understand


Learning Outcome: 07.02.02 Explain why ATP is both an input and output of glycolysis.
Section: 07.02
Topic: ATP Yield

27. The final products of glycolysis are


A. 2 pyruvate, 2 ATP, and 2 NADH + H+.
B. 1 pyruvate and 2 ATP.
C. 1 pyruvate and 2 NADH + H+.
D. 2 ATP and 2 NADH + H+.
E. 2 pyruvate.

Glycolysis results in 2 ATP, 2 NADH + H+, and 2 pyruvate.

Bloom's Level: 1. Remember


Learning Outcome: 07.02.01 Describe the location and inputs and outputs of glycolysis.
Section: 07.02
Topic: Glycolysis

7-13
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

True / False Questions

28. Pyruvate contains less chemical energy than glucose.


TRUE

Glucose is broken down, releasing energy, during glycolysis. Therefore pyruvate does
contain less energy than glucose.

Bloom's Level: 2. Understand


Learning Outcome: 07.02.01 Describe the location and inputs and outputs of glycolysis.
Section: 07.02
Topic: ATP Yield

Multiple Choice Questions

29. Pyruvate is converted to a two-carbon acetyl group attached to coenzyme A (CoA), and
CO2 is given off. This phase is called
A. substrate-level ATP synthesis.
B. the preparatory reaction.
C. the electron transport chain.
D. the citric acid cycle.
E. fermentation.

This reaction is called the preparatory reaction.

Bloom's Level: 2. Understand


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Preparatory Reaction

7-14
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

30. Which is NOT correct about the preparatory reaction?


A. It connects glycolysis to the citric acid cycle.
B. CO2 is given off.
C. Pyruvate is converted to a two-carbon acetyl group.
D. NAD+ goes to NADH + H+ as acetyl-CoA forms.
E. The reaction occurs once per glucose molecule.

All of the statements are true, except that the reaction occurs twice per glucose molecule,
because one glucose is converted into 2 pyruvates.

Bloom's Level: 4. Analyze


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Preparatory Reaction

31. Where does the preparatory reaction take place within the cell?
A. mitochondrial matrix
B. mitochondrial cristae
C. nucleus
D. cytoplasm
E. endoplasmic reticulum

The preparatory reaction takes place within the mitochondrial matrix.

Bloom's Level: 1. Remember


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Preparatory Reaction

7-15
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

32. The molecule that is found at the beginning and end of the citric acid cycle is
A. four-carbon molecule.
B. pyruvate.
C. lactate.
D. glucose.
E. RuBP.

The first and last molecule in the citric acid cycle is a C4 molecule. Pyruvate is the last
molecule of glycolysis while glucose is the first molecule of glycolysis. Lactate is a
fermentation production and RuBP is in the Calvin cycle.

Bloom's Level: 2. Understand


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Citric Acid Cycle/Krebs Cycle

33. Which pathway in cellular respiration will produce ATP, NADH2, and carbon dioxide?
A. glycolysis
B. preparatory reaction
C. citric acid cycle
D. electron transport chain
E. photosynthesis

Only the citric acid cycle produces all three products.

Bloom's Level: 1. Remember


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Citric Acid Cycle/Krebs Cycle

7-16
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

34. Which stage(s) will produce carbon dioxide in cellular respiration?


A. glycolysis
B. both the preparatory reaction and the citric acid cycle
C. citric acid cycle
D. both glycolysis and the electron transport chain
E. both the preparatory reaction and the citric acid cycle

Both the preparation reaction and the citric acid cycle produce carbon dioxide.

Bloom's Level: 2. Understand


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Cellular Respiration

35. Which of the following statements is NOT true?


A. The end product of glycolysis is pyruvate.
B. The citric acid cycle begins and ends with pyruvate.
C. NADH2 will eventually produce three ATP molecules.
D. Aerobic respiration of glucose has four phases.
E. Aerobic respiration uses oxygen and releases carbon dioxide.

The citric acid cycle begins and ends with a C4 molecule.

Bloom's Level: 2. Understand


Learning Outcome: 07.04.03 Identify how each stage of the aerobic pathway contributes to the generation of ATP in a cell.
Section: 07.04
Topic: Cellular Respiration

7-17
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

36. For the complete respiration of one molecule of glucose, the citric acid cycle must turn a
total of
A. one time.
B. two times.
C. three times.
D. four times.
E. six times.

Because two pyruvate are formed from one glucose molecule, the citric acid cycle must turn
two times per glucose molecule.

Bloom's Level: 2. Understand


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Citric Acid Cycle/Krebs Cycle

37. An acetyl group contains how many carbons?


A. one
B. two
C. three
D. four
E. six

An acetyl group contains two carbons. Pyruvate is converted into one acetyl group (two
carbons) and one carbon dioxide molecule (one
carbon).

Bloom's Level: 1. Remember


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Preparatory Reaction

7-18
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

38. The number of ATPs produced directly as a result of one turn of the citric acid cycle is
A. 1.
B. 2.
C. 12.
D. 14.
E. 16.

Each turn of the citric acid cycle produces one ATP. Per glucose molecule, two ATPs are
formed.

Bloom's Level: 1. Remember


Learning Outcome: 07.04.03 Identify how each stage of the aerobic pathway contributes to the generation of ATP in a cell.
Section: 07.04
Topic: ATP Yield

39. How many NADH + H+ are produced by the citric acid cycle per turn?
A. one
B. two
C. three
D. four
E. six

Three NADH + H+ molecules are produced during one turn of the citric acid cycle.

Bloom's Level: 1. Remember


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Citric Acid Cycle/Krebs Cycle

7-19
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

40. Which is a correct association of mitochondrion structure and phase of cellular


respiration?
A. matrix - electron transport chain
B. cristae - preparatory reaction
C. matrix - citric acid cycle
D. matrix - glycolysis
E. cristae - glycolysis

Glycolysis occurs in the cytoplasm. The preparatory reaction and citric acid cycle occur in
the matrix, while the electron transport chain occurs in the cristae.

Bloom's Level: 4. Analyze


Learning Outcome: 07.04.01 Recognize the role of the mitochondria in cellular respiration.
Section: 07.04
Topic: Citric Acid Cycle/Krebs Cycle

41. Some desert organisms can live out their life without ever drinking liquid water. What
phase(s) of cellular respiration could provide the organism with water?
A. glycolysis
B. citric acid cycle
C. electron transport chain
D. glycolysis and electron transport chain
E. citric acid cycle and electron transport chain

Both glycolysis and the electron transport chain produce water.

Bloom's Level: 4. Analyze


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Electron Transport Chain

7-20
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

42. What phase(s) of cellular respiration produce(s) NADH + H+?


A. glycolysis
B. preparatory reaction
C. citric acid cycle
D. glycolysis and preparatory reaction
E. glycolysis, preparatory reaction, and citric acid cycle

All three phases of these reactions produce NADH + H+.

Bloom's Level: 2. Understand


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Cellular Respiration

43. The final acceptor for hydrogen ions in aerobic cellular respiration is
A. oxygen.
B. pyruvate.
C. CoA.
D. glucose.
E. carbon dioxide.

Oxygen takes the hydrogen ions and becomes water.

Bloom's Level: 1. Remember


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Electron Transport Chain

7-21
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

44. The production of ATP as a result of an electrochemical gradient is called


A. glycolysis.
B. substrate-level phosphorylation.
C. chemiosmosis.
D. deamination.
E. oxidative phosphorylation.

Chemiosmosis is when ATP production is tied to an electrochemical gradient, as in


mitochondria.

Bloom's Level: 1. Remember


Learning Outcome: 07.04.01 Recognize the role of the mitochondria in cellular respiration.
Section: 07.04
Topic: ATP Yield

45. Which of the following would not slow down the electron transport system's production
of ATP?
A. Limit the amount of oxygen available.
B. Decrease use of ATP and thus reduce available ADP.
C. Reduce synthesis of NAD+ and FAD.
D. Add an NADH reductase inhibitor.
E. Increase the pumping of hydrogen ions into the intermembrane space of the mitochondria.

Increasing the pumping of hydrogen ions into the intermembrane space would actually
increase the amount of ATP produced.

Bloom's Level: 4. Analyze


Learning Outcome: 07.04.03 Identify how each stage of the aerobic pathway contributes to the generation of ATP in a cell.
Section: 07.04
Topic: ATP Yield

7-22
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

46. If we developed a molecule that blocked the ATP channel protein, what would be the first
immediate effect?
A. accumulation of ATP in the mitochondrial matrix
B. accumulation of NADH in the mitochondrial matrix
C. no energy to pump hydrogen ions into the intermembrane space of a mitochondrion
D. reversal of the hydrogen ion gradient
E. immediate blockage of the cytochrome molecules

The ATP channel protein allows ATP to leave the mitochondrial matrix and enter the
intermembrane space. Therefore, if it were blocked, ATP would accumulate in the matrix.

Bloom's Level: 4. Analyze


Learning Outcome: 07.04.03 Identify how each stage of the aerobic pathway contributes to the generation of ATP in a cell.
Section: 07.04
Topic: ATP Yield

47. The carriers of the electron transport chain are located


A. in the matrix of the mitochondria.
B. on the outer mitochondrial membrane.
C. on the cristae of the mitochondria.
D. within the intermembrane space.
E. within the cytoplasm of the cell.

The electron transport chain carriers are located within the mitochondrial cristae.

Bloom's Level: 1. Remember


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Electron Transport Chain

7-23
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

48. Why does chemiosmosis require a membrane?


A. to anchor proteins within the mitochondria
B. because the phospholipids are involved in the electron transport chain
C. to separate two compartments of the cell to allow for gradient formation
D. to generate H+ from water
E. to provide a large surface area

Chemiosmosis requires two separate compartments to allow for the formation of a gradient.
The membrane is similar to using a dam to hold back water in order to generate electricity.

Bloom's Level: 4. Analyze


Learning Outcome: 07.04.03 Identify how each stage of the aerobic pathway contributes to the generation of ATP in a cell.
Section: 07.04
Topic: ATP Yield

49. The ATP synthase complex is located in the


A. cytoplasm outside the mitochondria.
B. matrix inside the mitochondria.
C. cristae of the mitochondria.
D. outer membrane of the mitochondria.
E. plasma membrane of the cell.

The ATP synthase complex is in the cristae of the mitochondria.

Bloom's Level: 1. Remember


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: ATP Yield

7-24
Copyright © 2017 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 07 - Cellular Respiration

50. The largest number of ATP molecules is produced in which phase of cellular respiration?

A. glycolysis
B. preparation reaction
C. citric acid cycle
D. electron transport chain
E. Calvin cycle

The electron transport chain produces the most ATP: 32-34 ATP.

Bloom's Level: 2. Understand


Learning Outcome: 07.04.03 Identify how each stage of the aerobic pathway contributes to the generation of ATP in a cell.
Section: 07.04
Topic: Electron Transport Chain

51. Why does FADH2 result in fewer ATP than NADH + H+?
A. FADH2 only contains one electron.
B. FADH2 only contains one hydrogen ion.
C. FADH2 drops its electrons off lower on the electron transport chain.
D. FADH2 drops its electrons off higher on the electron transport chain.
E. FADH2 drops its electrons off to oxygen.

FADH2 drops its electrons off lower on the electron transport chain than does NADH + H+.

Bloom's Level: 3. Apply


Learning Outcome: 07.04.03 Identify how each stage of the aerobic pathway contributes to the generation of ATP in a cell.
Section: 07.04
Topic: ATP Yield

7-25
Copyright © 2017 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 07 - Cellular Respiration

52. In cellular respiration, what is the relationship between the energy content of the reactants
(glucose and O2) and products (CO2 and H2O)?
A. The energy content of the reactants (glucose and O2) must equal the energy content of the
products (CO2 and H2O).
B. The energy content of the reactants (glucose and O2) must be greater than the energy
content of the products (CO2 and H2O).
C. The energy content of the reactants (glucose and O2) must be less than the energy content
of the products (CO2 and H2O).
D. There is no relationship between the energy content of the reactants (glucose and O2) and
the energy content of the products (CO2 and H2O).
E. There is no relationship between O2 and H2O, but the energy content of glucose is less
than that of CO2.

Glucose is a high-energy molecule while carbon dioxide is low energy. The energy content
of the reactants is greater than that of the products because ATP is formed.

Bloom's Level: 4. Analyze


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Cellular Respiration

53. The energy difference between the reactant glucose and oxygen molecules and the
product water and carbon dioxide is 686 kilocalories, yet the 36 ATP molecules produced are
only storing 263 kilocalories in their outermost phosphate bond. The rest of the energy went
A. to the ADP fragment of the ATP molecule.
B. into providing the energy for life.
C. to power the electron transport chain.
D. to provide heat that is soon lost from the organism.
E. nowhere, but was destroyed.

The remainder of the energy is lost as heat. Energy cannot be created or destroyed.

Bloom's Level: 2. Understand


Learning Outcome: 07.04.01 Recognize the role of the mitochondria in cellular respiration.
Section: 07.04
Topic: ATP Yield

7-26
Copyright © 2017 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 07 - Cellular Respiration

True / False Questions

54. All of the ATP molecules formed by the complete oxidation of glucose result from the
electron transfer chain.
FALSE

Some of the ATP come from glycolysis and the citric acid cycle.

Bloom's Level: 1. Remember


Learning Outcome: 07.04.03 Identify how each stage of the aerobic pathway contributes to the generation of ATP in a cell.
Section: 07.04
Topic: ATP Yield

55. The citric acid cycle turns once for each original glucose molecule.
FALSE

Because each original glucose molecule is broken into two pyruvate molecules, the citric acid
cycle turns twice for each original glucose molecule.

Bloom's Level: 1. Remember


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Citric Acid Cycle/Krebs Cycle

7-27
Copyright © 2017 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 07 - Cellular Respiration

Multiple Choice Questions

56. Pyruvate can be converted to lactate instead of going to the preparatory reaction. Why
does this occur?
A. The cells need lactate to produce ATP.
B. There is no sunlight.
C. The cells doing the reaction are prokaryotes.
D. Oxygen is not available.
E. There is a shortage of glucose.

Pyruvate is converted into lactate during fermentation, which occurs when oxygen is not
available.

Bloom's Level: 2. Understand


Learning Outcome: 07.03.01 Explain how ATP can continue to be produced in the absence of oxygen.
Section: 07.03
Topic: Fermentation and Anaerobic Respiration

57. Which of the following statements about fermentation is not true?


A. Fermentation involves the citric acid cycle.
B. Fermentation does not require oxygen.
C. Fermentation can produce lactic acid.
D. Fermentation produces a net two ATP molecules.
E. Fermentation can produce alcohol.

Fermentation does not use the citric acid cycle.

Bloom's Level: 2. Understand


Learning Outcome: 07.03.01 Explain how ATP can continue to be produced in the absence of oxygen.
Section: 07.03
Topic: Fermentation and Anaerobic Respiration

7-28
Copyright © 2017 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 07 - Cellular Respiration

58. Why is fermentation essential to humans?


A. It is the best reaction we can utilize to produce ATP.
B. It produces lactate, which is essential for humans.
C. It produces carbon dioxide, which is necessary for our cells.
D. It generates the NAD+ we need for metabolism.
E. It is essential when we need a rapid burst of energy.

Fermentation provides a rapid burst of ATP and thus muscle cells use fermentation when
working vigorously over a short period of time when oxygen is temporarily limited.

Bloom's Level: 3. Apply


Learning Outcome: 07.03.02 Describe the advantages and disadvantages of fermentation.
Section: 07.03
Topic: Fermentation and Anaerobic Respiration

59. Muscles undergo fermentation when


A. no oxygen is available.
B. no water is available.
C. no carbon dioxide is available.
D. no ATP is available.
E. no pyruvate is available.

Fermentation occurs when oxygen is not available.

Bloom's Level: 2. Understand


Learning Outcome: 07.03.02 Describe the advantages and disadvantages of fermentation.
Section: 07.03
Topic: Fermentation and Anaerobic Respiration

7-29
Copyright © 2017 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 07 - Cellular Respiration

60. Why do organisms without oxygen need to convert pyruvate to lactate?


A. in order to regenerate NAD+
B. because lactate is needed to produce ATP
C. because pyruvate is toxic to the cells
D. in order to use lactate in the citric acid cycle
E. because the conversion provides much more ATP for the cell

Pyruvate is reduced to lactate when oxygen is unavailable in order to regenerate NAD+ to be


used during glycolysis.

Bloom's Level: 3. Apply


Learning Outcome: 07.03.01 Explain how ATP can continue to be produced in the absence of oxygen.
Section: 07.03
Topic: Fermentation and Anaerobic Respiration

61. Fermentation is inefficient in using the energy found in food molecules and the resulting
alcohol can be toxic to the organism producing it. Which of the following is not a reason why
an organism would utilize fermentation?
A. If glucose levels are not high, there may be time to disperse the toxic alcohol waste.
B. The organism can survive short spells of anaerobic conditions and maintain growth and
reproduction.
C. Fermentation can provide a rapid burst of ATP since it does not have to go through the full
breakdown cycle.
D. Fermentation is the preferred process, even when oxygen is available.
E. For very small organisms, fermentation can be a simple process and is less complicated
than cellular respiration.

Fermentation is not preferred but is utilized only when oxygen is unavailable.

Bloom's Level: 4. Analyze


Learning Outcome: 07.03.02 Describe the advantages and disadvantages of fermentation.
Section: 07.03
Topic: Fermentation and Anaerobic Respiration

7-30
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McGraw-Hill Education.
Chapter 07 - Cellular Respiration

62. Which of the following is not a consequence of the lactate that results from fermentation
in the muscles?
A. It triggers ongoing heavier breathing to provide further oxygen for the muscles.
B. Much of the lactate is transported to the liver where it is converted to pyruvate.
C. Some lactate converted to pyruvate is converted back to glucose.
D. Some lactate converted to pyruvate is then completely broken down.
E. It is stored in muscle cells for later ATP production.

Lactate causes that muscle "burn" and is not stored in muscle cells.

Bloom's Level: 2. Understand


Learning Outcome: 07.03.02 Describe the advantages and disadvantages of fermentation.
Section: 07.03
Topic: Fermentation and Anaerobic Respiration

63. Which of the following is not an example of fermentation used by organisms to produce
ATP?
A. bacterial cells producing lactate
B. bacterial cells producing alcohol
C. human cells producing lactate
D. human cells producing lactate
E. yeast cells producing alcohol

Humans do not produce alcohol from fermentation.

Bloom's Level: 2. Understand


Learning Outcome: 07.03.02 Describe the advantages and disadvantages of fermentation.
Section: 07.03
Topic: Fermentation and Anaerobic Respiration

7-31
Copyright © 2017 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 07 - Cellular Respiration

True / False Questions

64. The only end product of alcoholic fermentation is the alcohol.


FALSE

Carbon dioxide is produced along with the alcohol.

Bloom's Level: 1. Remember


Learning Outcome: 07.03.02 Describe the advantages and disadvantages of fermentation.
Section: 07.03
Topic: Fermentation and Anaerobic Respiration

65. Fermentation follows glycolysis in some cells if oxygen is not available.


TRUE

Glycolysis converts glucose to pyruvate. Pyruvate can either be fermented if oxygen is not
available or enter the preparatory reaction if oxygen is available.

Bloom's Level: 2. Understand


Learning Outcome: 07.03.01 Explain how ATP can continue to be produced in the absence of oxygen.
Section: 07.03
Topic: Fermentation and Anaerobic Respiration

66. Fermentation is the process that allows bread to rise.


TRUE

Fermentation produces alcohol and carbon dioxide. The carbon dioxide produces bubbles
that cause bread to rise.

Bloom's Level: 3. Apply


Learning Outcome: 07.03.02 Describe the advantages and disadvantages of fermentation.
Section: 07.03
Topic: Fermentation and Anaerobic Respiration

7-32
Copyright © 2017 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 07 - Cellular Respiration

Short Answer Questions

67. List, in order, the stages of aerobic cellular respiration and indicate where they occur in
the cell.

Glycolysis is first and it occurs within the cytoplasm of the cell.


The preparatory reaction is second and it occurs within the matrix of the mitochondria.
The citric acid cycle is third and it occurs within the matrix of the mitochondria.
The electron transport chain is fourth and it occurs within the cristae of the mitochondria.

Bloom's Level: 6. Create


Learning Outcome: 07.01.03 Summarize the phases of cellular respiration and indicate where they occur in a cell.
Section: 07.01
Topic: Cellular Respiration

Multiple Choice Questions

68. What are the correct outputs, during the citric acid cycle, from one molecule of glucose?
A. 6 NADH, 4 CO2, 2 ATP, 2 FADH2
B. 3 NADH, 2 CO2, ATP, FADH2
C. 2 acetyl - CoA & 2 CO2
D. 6 NADH, 2 CO2, 4 ATP, 6 FADH2
E. 2 pyruvates, 2 NADH, 2 ADH, and 4 ATP

The correct outputs, during the citric acid cycle from one molecule of glucose is 6 NADH, 4
CO2, 2 ATP, 2 FADH2. The glucose will split into two pyruvates, each of which will be
converted into acetyl CoA which then will go through the citric acid cycle. Two acetyl, CoA
& 2 CO2, are the end products of the preparatory reaction. Two pyruvates, 2 NADH, 2 ADH,
and 4 ATP are the end products of glycolysis.

Bloom's Level: 5. Evaluate


Learning Outcome: 07.04.02 Summarize the inputs and outputs of the preparatory reaction, the citric acid cycle, and the electron transport
chain.
Section: 07.04
Topic: Citric Acid Cycle/Krebs Cycle

7-33
Copyright © 2017 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 07 - Cellular Respiration

69. What is the most likely reason that cellular respiration would shift from an aerobic state
into an anaerobic state?
A. The individual was exercising at a level beyond their capability and entered into oxygen
debt.
B. A smoker has developed emphysema and has decreased lung capacity.
C. The individual has had a stroke in the left hemisphere of their brain.
D. None of the answer choices could cause an individual to shift into an anaerobic state.
E. All of the answer choices are reasons that an individual could shift into an anaerobic state.

All of the choices are reasons that an individual could shift into an anaerobic state. Any
reason that decreases the amount of available oxygen can cause a shift into anaerobic
respiration.

Bloom's Level: 5. Evaluate


Learning Outcome: 07.03.01 Explain how ATP can continue to be produced in the absence of oxygen.
Section: 07.03
Topic: Cellular Respiration

Short Answer Questions

70. List the inputs and outputs of glycolysis.

Inputs of glycolysis include: glucose, 2 NAD+, 2 ATP, and 4 ADP + 4 P.


Outputs of glycolysis include: 2 pyruvates, 2 NADH, 2 ADP, and 4 ATP.
The net gain of glycolysis is 2 ATP.

Bloom's Level: 6. Create


Learning Outcome: 07.02.02 Explain why ATP is both an input and output of glycolysis.
Section: 07.02
Topic: Glycolysis

7-34
Copyright © 2017 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Test Bank for Inquiry into Life 15th Edition

Chapter 07 - Cellular Respiration

Multiple Choice Questions

71. What are the input requirements of glycolysis?


A. 2 ATP, 2 NAD+, glucose, and 4 ADP
B. 4 ATP, 2 NAD+, glucose, and 4 ADP
C. 2 pyruvates, 2 NADH, and 2 ADP
D. 2 ATP, 4 NAD+, glucose, and 4 ADP
E. 2 ATP, 2 NAD+, glucose, and 2 ADP

The inputs of glycolysis are 2 ATP, 2 NAD+, glucose, and 4 ADP. 2 pyruvates, 2 NADH,
and 2 ADP are the outputs of glycolysis. 2 ATP, 2 NAD+, glucose, and 2 ADP are the inputs
of glycolysis.

Bloom's Level: 2. Understand


Learning Outcome: 07.02.01 Describe the location and inputs and outputs of glycolysis.
Section: 07.02
Topic: Glycolysis

Short Answer Questions

72. Write out the overall equation for cellular respiration.

C6H12O6 + 6O2 = 6CO2 + 6H2O


ADP + P = 36 - 38 ATP

Bloom's Level: 6. Create


Learning Outcome: 07.01.01 Describe the overall equation for cellular respiration.
Section: 07.01
Topic: Cellular Respiration

7-35
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McGraw-Hill Education.

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