1) What is the difference between a plasma membrane and a cell surface
membrane? (1) 2) What is the role of cholesterol in cell surface membranes? (3) 3) Describe the basic structure of cell surface membranes, and of membrane bound organelles in eukaryotes e.g. chloroplast and mitochondria (3) 4) Describe the fluid mosaic model of the cell surface membrane (6) 5) Why is this model known as the fluid mosaic model? (2) 6) What is the difference between an extrinsic and intrinsic protein? (1) 7) What is the role of a glycoprotein? (1) 8) What is the role of a glycolipid? (1) 9) Define simple diffusion (1) 10)Define facilitated diffusion (1) 11)Define osmosis (1) 12)Define active transport (1) 13)How is the simple diffusion of many molecules restricted across the phospholipid bilayer? (1) 14)Explain the process of co-transport of amino acids/glucose in the ileum (5) 15)How are mitochondria adapted for carrying out a fast rate of respiration? (2) 16)Name 3 factors that can affect the rate of facilitated diffusion (3) Answers
1) All membranes are ‘plasma membranes’ and are all made up of a
phospholipid bilayer. The term ‘cell-surface membrane’ is only used to describe the plasma membrane that makes up the cell membrane 2) Regulates fluidity, increases stability and has a role in preventing loss of water as it is hydrophobic 3) a. Phospholipids are arranged as bilayer in membrane b. The phosphate head is hydrophilic/polar and the fatty acid tail is hydrophobic/non-polar c. The heads are located on the outside and the tails are attracted to each other on the inside 4) a. The cell surface membrane is a phospholipid bilayer b. Which is made up of phospholipids and proteins c. Phospholipid molecules are arranged ‘Tails to tails’ d. With ‘floating’ protein molecules that are able to move in the membrane e. Intrinsic proteins extend through bilayer f. Extrinsic proteins in one single outer layer only; g. Channel proteins are embedded into the cell surface membrane which have a role in transport of molecules (e.g. water, ions) h. Glycoproteins are embedded into the cell surface membrane which have a role as receptors of hormones/neurotransmitters i. Presence of cholesterol in the cell surface membrane j. which regulates fluidity, increases stability and has a role in preventing loss of water as it is hydrophobic 5) a. Molecules within the membrane are able to move b. due to the mixture of phospholipid and protein / arrangement of protein 6) Intrinsic proteins extend through the bilayer whereas extrinsic proteins are in a single outer layer 7) Are embedded into the cell surface membrane which have a role as receptors of hormones/neurotransmitters 8) Used in cell recognition and for stability of cell membrane 9) Movement of non-polar/lipid soluble molecules from an area of high concentration to an area of low concentration, down the concentration gradient. Doesn’t use carrier or channel proteins or ATP 10)Movement of polar/water soluble molecules from an area of high concentration to an area of low concentration, down the concentration gradient. Uses a carrier or channel proteins but doesn’t use ATP 11)Movement of water molecules from a high water potential to a low water potential through, down the water potential gradient. Uses channel proteins but doesn’t use ATP 12)Movement of molecules from an area of low concentration to an area of high concentration, against the concentration gradient. Uses a carrier protein and energy from the hydrolysis of ATP 13)Only lipid soluble molecules (not water soluble) can diffuse across due to the hydrophobic nature of the fatty acid tails of the phospholipids 14) a. Sodium ions are actively transported from the epithelial cell to the blood b. This maintains/forms a concentration gradient for sodium ions to enter the epithelial cells from the ileum by diffusion c. Glucose/amino acid moves into the epithelial cell from the ileum with the sodium ion d. Via (carrier / channel) protein e. Glucose/amino acid then moves into blood by facilitated diffusion 15) a. They have a folded inner membrane that provides a large surface area b. to have an increased number of protein channels and carrier proteins that are involved in the respiratory reactions 16) a. Having a large surface area with more channel proteins embedded into it b. Having a steep concentration gradient c. Having a higher temperature