Definition : Benign prostatic hyperplasia (BPH) : is one of the most common diseases in aging men. Background 1. It can cause bothersome lower urinary tract symptoms that affect quality of life by interfering with normal daily activities and sleep patterns. 2. BPH typically occurs in men older than 40 years of age. By the time they reach 60 years of age, 50% of men have BPH. 3. It affects as many as 90% of men by 85 years of age. 4. BPH is the second most common cause of surgical intervention in men older than 60 years of age. Pathophysiology 1. The cause of BPH is not well understood, but testicular androgens have been implicated. 2. Dihydrotestosterone (DHT), a metabolite of testosterone, is a critical mediator of prostatic growth. 3. Estrogens may also play a role in the cause of BPH; BPH generally occurs when men have elevated estrogen levels and when prostate tissue becomes more sensitive to estrogens and less responsive to DHT. 4. Smoking, heavy alcohol consumption, obesity, reduced activity level, hypertension, heart disease, diabetes, and a Western diet (high in animal fat and protein and refined carbohydrates, low in fiber) . 5. The hypertrophied lobes of the prostate may obstruct the bladder neck or urethra, causing incomplete emptying of the bladder and urinary retention. 6. As a result, a gradual dilation of the ureters (hydroureter) and kidneys (hydronephrosis) can occur. 7. Urinary retention may result in UTIs because urine that remains in the urinary tract serves as a medium for infective organisms. Clinical Manifestations 1. Obstructive and irritative symptoms may include urinary frequency. 2. Urgency. 3. Nocturia. 4. hesitancy in starting urination. 5. decreased and intermittent force of stream and the sensation of incomplete bladder emptying. 6. abdominal straining with urination. 7. a decrease in the volume and force of the urinary stream, dribbling (urine dribbles out after urination. 8. azotemia (accumulation of nitrogenous waste products) and renal failure. 9. Fatigue. 10. Anorexia. 11. Nausea, vomiting, and pelvic discomfort. Assessment and Diagnostic Findings 1. The health history focuses on the urinary tract. 2. previous surgical procedures. 3. general health issues. 4. family history of prostate disease. Reference
Brunner, L. S., Suddarth, D. S., Smeltzer, S. C. O., & Bare, B. G. (2018),
Brunner & Suddarth's textbook of medical-surgical nursing (14th ed.), Philadelphia: Lippincott Williams & Wilkins.