UNICORN start 1.

3
Release Notes

Introduction
This document describes the implemented changes in the released version of
UNICORN™ start.

Compatibility

UNICORN Windows® 10 operating system SQL Server® edition

start version
Professional
1.3 Education 64-bit 2019 Express SP3 (x64)
Enterprise US
English
1.2 Professional 64-bit 2014 Express SP3 (x86) or (x64)
1.1 Professional 32-bit & 64-bit 2008 R2 Express (x86)

Release 1.3
Features
• A new license file is required to use the UNICORN start 1.3 application. The license file
of the previous version of UNICORN start will not work with UNICORN start 1.3.
Users upgrading to UNICORN start 1.3 must contact their regional customer support
team referring to product number: 29704233 (Upgrade to UNICORN start 1.3 ESD +
eLicense) along with the previous version license activation ID. Please refer to the
UNICORN start homepage for more details: https://www.cytivalifesciences.com/shop/
chromatography/software/unicorn-start-p-00811.

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 • Corrected the installation and system connection issues related to Language &
Regional settings. During the installation, follow the Language and regional settings
instructions to avoid installation and system connection-related issues.
• Corrected UNICORN start disconnecting from the instrument during long method
runs.
• UNICORN start 1.3 software has been upgraded with SQL Server 2019.
• During UNICORN start 1.3 installation, the link to configure the eLicense has been
updated.
• Corrected the pump wash defect under System Control → Method Run → Pre defined
→ System preparation → Pump Wash. Pump wash A and B options are now available.
• Updated the system performance test result file location path in Method Notes.
• Implemented the console app (Update Stored Procedure.exe) to make the earlier
UNICORN start databases compatible with the rebranded application.
• Rebranding of UNICORN start Namespaces, Headers and Assembly information to
Cytiva, from GE Healthcare.
• UNICORN start 1.3 has been updated to accommodate rebranding changes for
Vendor ID (VID).

Known limitations
• WINUSB for GE Healthcare remains in the Control Panel, it is a redundant driver, it will
not affect UNICORN start 1.3. User requires to remove it manually.
• All known limitations in UNICORN start 1.2 also remain for UNICORN start 1.3.

Release 1.2
Features
• Mismatch between the valve position and the process picture.
• Flow-rate could not be set with a decimal point.
• When more than one sample application phase was added in a protocol, the sample
application flow-rate was set to default.
• Issue with the concentration at accepting value being out of range.
• In the system error report, the IC version was V4.7 while the installation report gave it
as V4.6.
• Fractionation tube number mismatch in volume and time axis.
• Issues with display resolution in both Windows 7 and Windows 10.
• Issues with button visibility in the software help window in Windows 10.

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 • UNICORN start upgrade for SQL Server 2014.
• After an upgrade, UNICORN start failed to migrate the method and results data from
older versions of the software.

Known limitations
• When executing the feed flow instruction manually, the initial feed flow instruction is
not logged in the run log.
• Save anyway is not automatically disabled for imported methods that contains errors.
When opening methods created using UNICORN start 1.0 or 1.1, never save a method
that contains instructions that are not supported by the system. The method will
become corrupt and cannot be recovered.
• The system will be on hold before and after the sample application phase using
sample loop.
• The USB cable needs to be reconnected to the PC after enabling or disabling the Frac
option from the ÄKTA start instrument touchscreen.
• The user interface does not fit the screen size and text is misaligned in boxes.
• When connecting a USB cable to a PC for the first time, the user has to unplug and
then plug-in the cable to establish the connection. The issue has been observed in
Windows 7 and Windows 10.
• Methods created using UNICORN start 1.0 or 1.1, containing multiple sample
application phases with different flow rates, should not be imported into UNICORN
start 1.2. They might not provide correct output. The issue is fixed in UNICORN start
1.2. Users should create new methods for such purposes.

Release 1.1
Features
UNICORN start 1.1 corrects the defect that prevented the correct display of
fractionation marks in a UNICORN result file. The defect occurred if the run was executed
from an UNICORN start instrument and the result file was subsequently imported to a
computer using a USB memory stick.
Prior to correction, the fractionation marks and run logs were not adjusted correctly to
the injection mark, if the imported result file had the following features:
• Injection marks displayed
• Fractionation marks displayed
• Setting Adjust retention zero to injection number enabled (default setting)
After the correction, the fractionation marks and run logs are displayed correctly in the
imported result file.

UNICORN start 1.3 Release Notes 29695178 AA 3

 UNICORN start 1.1 corrects the defect in the result files that are imported after the
installation of the Service Pack update. The files that were imported prior to the
installation must be re-imported to apply the correction.
UNICORN start 1.1 corrects the defect that caused UNICORN start interface to freeze
while method was still running on the instrument. The USB driver is updated to reduce
the frequency of occurrence and to improve the connection stability.

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cytiva.com/unicornstart
Cytiva and the Drop logo are trademarks of Global Life Sciences IP Holdco LLC or an affiliate.
ÄKTA and UNICORN are trademarks of Global Life Sciences Solutions USA LLC or an affiliate doing business as Cytiva.
Windows and SQL Server are registered trademarks of Microsoft Corporation.
All other third-party trademarks are the property of their respective owners.
© 2021 Cytiva
UNICORN © 2021 Cytiva
Any use of UNICORN is subject to Cytiva Standard Software End-User License Agreement for Life Sciences Software Products. A
copy of this Standard Software End-User License Agreement is available on request.
All goods and services are sold subject to the terms and conditions of sale of the supplying company operating within the Cytiva
business. A copy of those terms and conditions is available on request. Contact your local Cytiva representative for the most
current information.
For local office contact information, visit cytiva.com/contact
29695178 AA V:2 08/2021