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1.

Which of the following is accessible to emetogenic stimuli in blood or CSF, rich in D2 receptors
and opioid receptors?
a) Chemoreceptors Trigger Zone (CTZ)
b) CNS/ Vestibular system
c) Vagal and spinal afferent nerves from GIT
d) Limbic system
2. Which of the following is associated with motion sickness?
a) Chemoreceptors Trigger Zone (CTZ)
b) CNS/ Vestibular system
c) Vagal and spinal afferent nerves from GIT
d) Limbic system
3. Serotonin 5-HT3 Antagonist are used for:
a) Chemotherapy induced N/V
b) Post operative
c) Radiation therapy
d) a and c
e) all of the above
4. Which of the following require dose adjustment for hepatic dysfunction
a) Ondansetron (zofran)
b) Granisetron
c) Dolasetron
D) Palonosetron
e) All of the above
5. Which area of the brain is responsible for control of chemically induced vomiting?
A) Vomiting center
B) Medulla
C) Cerebral cortex
D) Chemoreceptor Trigger Zone
6. Which of the following dose not require dose adjustment for renal dysfunction
a) Ondansetron (zofran)
b) Granisetron
c) Dolaseetron
D) Palonosetron
e) All of the above
7. A patient who is about to undergo there 3rd cycle of chemotherapy develops sever nausea and
vomiting one night prior to her next round of chemotherapy. which of the following is the best
description of the type of nausea and vomiting this patient is experiencing
A) Acute CINV
B) Delayed CINV
C) Anticipatory nausea and vomiting
D) Breakthrough nausea and vomiting
8. Which of the following medication would be considered first line in the prevention of nausea and
vomiting related to motion sickness?
A) Cetirizine
B) Ginger
C) Scopalamine
D) Ondansetron

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