Sunder Deep Pharmacy College, Ghaziabad

Pharmaceutical Organic Chemistry-1

Long Questions

1. What are SN1 reactions. Discuss the kinetics, mechanism and factors
affecting the SN1 reactions.
2. What are SN2 reactions. Discuss the kinetics, mechanism and factors
affecting the SN1 reactions.
3. Give short notes on cannizzaro reaction with mechanism.
4. Give short notes on Aldol reaction with mechanism.
5. Define Sayzeff rule. Illustrate E2 (Elimination reaction) in details with
suitable examples.
6. Explains the evidence of E2 OR E1 reactions.
7. Define aliphatic amines. Discuss the basicity order in following aliphatic
amines compounds with reasons like inductive effect, Lewis theory and
pkb value
a) Methyl amine b ) Dimethyl amine c) Tertiary butyl amine
8. Explain Markovnikov's rule, statement in addition of HBr, HCl, HI to
alkenes examples.
9. Explain Anti- Markovnikov's rule or , statement and n addition of HBr,
HCl, HI to alkenes examples.
10. Explain ozonolysis with suitable examples.
11. Discuss the acidity order in following aliphatic amines compounds with
reasons inductive effect, arhenious theory and Pka value
b) HCOOH b ) CH3COOH c) ClCH2COOH D) CCl3COOH
12.Write a note on Diels Alder reactions with suitable examples.
13. Discuss the nomenclature of organic compounds like carboxylic acid
function group and carbonyl compounds.
Short Questions

1. Write the structure and uses of oxalic and succinic acid.

2. Write the structure and uses of vanillin and benzaldehyde
3. Write the IUPAC of following compound
CH3CH2CH2COOH
4. Two differentiate in E1 and E2 reactions
5. Define benzoin condensation
6. Two Identification test of alcohol.
7. Two Identification test of aldehyde/COOH
8. Define inductive effect.
9. Define alkyl halide with suitable examples.
10. Two chemical reactions of alkyl halide.
11. Structure and uses of acetyl salicylic acid.
12. Structure and uses of acetyl salicylic acid.
13. IUPAC NAME OF FOLOOWING COMPOUND
CH3CHCOCH2CH2CH3
14. Structure and uses of ethyl alcohol and benzyl acohol.
15. Write chemical reaction for perkin.
16. Qualitative test for carbonyl compound
17. Write the structure of benzil and benzoin
18. Reactivity order of alkyl halides in SN1 reactions
19. Reactivity order of alkyl halides in SN2 reactions.
20. Steric hindrance in SN2 reactions