Medication Mechanism of Action Indication Contraindication Side Effects Adverse Reaction Nursing

Responsibilities
Omeprazole Prevents the Omeprazole once a day, Those who have ● Headaches ● Stomach cramps ● Advise patient
10 mg IV OD ● Feeling sick ● Bloated feeling to avoid foods
H+/K+-ATPase system, first thing in the previously experienced
● Being sick ● Watery and that may cause
which is located at the morning. It will not hypersensitivity to the an increase in GI
(vomiting) or severe diarrhea
irritation.
secretory surface of affect your stomach, so medication or any of the diarrhea which may also
gastric parietal cells, you can take it with or dosage form's excipients. ● Stomach pain be bloody ● Instruct patients
● Constipation. sometimes to report
from secreting stomach without food.
● Flatulence ● Fever, nausea or bothersome or
acid. vomiting, or prolonged side
unusual effects, including
skin problems
tiredness or
(itching, rash) or
weakness. GI effects
(nausea,
diarrhea,
vomiting,
constipation,
heartburn,
flatulence,
abdominal pain).
 Drug Name Mechanism of Action Indication Contraindication Side Effects Adverse Effects Nursing
Responsibilities

Famotidine 10 mg ● Hypersensitivity ● Constipation and ● Monitor gastric

● Nausea
A competitive histamin-2 Used in gastrointestinal to other diarrhea pH and occult
Histamine-2 ● Abdominal ● Vomiting blood in patients
receptor antagonist that conditions related to acid
receptor discomfort ● Constipation with
stimulates the acid output secretion and treatment antagonists ● Dizziness gastrointestinal
by parietal cells via for pathological ● Fatigue and ● Difficulty bleeding
weakness
paracrine mechanism . hypersecretory breathing
● Insomnia ● Administer drug
About 20 to 50 times conditions in adults and ● Dry mouth at bedtime
more potent at inhibiting children. (gastric ulcers, ● Muscle pain or
cramps ● Administration
gastric acid secretion active duodenal ulcer, ● Nausea and of concurrent
than cimetidine and erosive esophagitis due vomiting antacid therapy
● Liver enzyme to relieve pain.
ranitidine. to gastroesophageal
abnormalities
reflux disease (GERD)) ● Switch to oral
medication as
soon as the
patient can
intake such a
drug and if
prescribed by the
physician.
 Drug Name Mechanism of Action Indication Contraindication Side Effects Adverse Effects Nursing
Responsibilities
Piperacillin + tazobactam Beta lactam antibiotic
400 mg IV q8 ● Patients with a ● Diarrhea ● Hives. ● Monitor signs of
that inhibits bacterial cell
Treat pneumonia and ● Rash ● Difficulty allergic reactions
wall synthesis. history of and anaphylaxis,
skin, gynecological, and ● Erythema breathing or
allergic reactions including
Tazobactam is a beta ● Pruritus swallowing.
abdominal (stomach pulmonary
lactamase inhibitor that to any of the ● Vomiting ● Wheezing. symptoms
area) infections caused ● Allergic reactions ● Severe diarrhea (tightness in the
has no intrinsic penicillins,
by bacteria ● Nausea, (watery or throat and chest,
antimicrobial activity but cephalosporins, ● Urticaria bloody stools) wheezing, cough
or beta-lactamase ● Superinfection that may occur dyspnea) or skin
prevents breakdown of
● Phlebitis, with or without reactions (rash,
beta lactam by beta inhibitors. pruritus,
● Thrombophlebitis fever and
urticaria).
lactamase enzyme. ● Dyspepsia and stomach cramps
insomnia. ● Notify physician
or nursing staff
immediately if
these reactions
occur.