Certainly!

Here are some multiple-choice questions (MCQs) related to IGF-1:

1. What is IGF-1? a. Insulin-Growth Factor 1 b. Interferon-Gamma Factor 1 c. Islet Granule

Factor 1 d. Interleukin Growth Factor 1
2. Where is IGF-1 primarily produced? a. Pancreas b. Liver c. Kidneys d. Adrenal Glands
3. Which hormone stimulates the production of IGF-1? a. Insulin b. Thyroid Hormone c.
Growth Hormone d. Cortisol
4. What is the main role of IGF-1 in the body? a. Regulating blood glucose levels b.
Promoting cell growth and division c. Enhancing immune function d. Controlling body
temperature
5. Which of the following is a target tissue for the actions of IGF-1? a. Heart b. Lungs c.
Bones d. All of the above
6. When is IGF-1 secretion typically highest in the human lifecycle? a. Childhood and
adolescence b. Young adulthood c. Middle age d. Elderly age
7. What is the relationship between IGF-1 and growth hormone (GH)? a. IGF-1 inhibits the
secretion of GH. b. GH inhibits the production of IGF-1. c. IGF-1 is produced in response to
GH stimulation. d. IGF-1 and GH have no functional relationship.
8. Which factor primarily regulates IGF-1 production? a. Blood glucose levels b. Sleep
patterns c. Growth hormone levels d. Thyroid hormone levels
9. In addition to its role in growth, what metabolic effect does IGF-1 have? a. Inhibits
protein synthesis b. Promotes protein breakdown c. Increases protein synthesis d. Decreases
protein breakdown
10. Deficiency in IGF-1 during growth stages can lead to: a. Increased height b. Dwarfism c.
Obesity d. Diabetes

Answers:

1. a
2. b
3. c
4. b
5. d
6. a
7. c
8. c
9. c
10. b
11. Which of the following statements about IGF-1 is true?
a. It is produced by the adrenal glands.
b. It primarily regulates blood glucose levels.
c. Its production is not influenced by growth hormone.
d. It plays a key role in bone and muscle growth.
12. What is the main signaling pathway through which IGF-1 exerts its effects
on cell growth and division?
a. JAK-STAT pathway
b. MAPK/ERK pathway
c. PI3K-Akt pathway
d. Wnt signaling pathway
13. In addition to the liver, where else is IGF-1 produced in the body? a. Kidneys
b. Pancreas c. Spleen d. Adipose tissue
14. What condition is associated with elevated levels of IGF-1 in adulthood? a.
Type 2 diabetes b. Gigantism c. Osteoporosis d. Hypothyroidism
15. How does IGF-1 influence protein metabolism? a. Inhibits protein synthesis b.
Increases protein breakdown c. Stimulates protein synthesis d. Has no effect on
protein metabolism
16. Which hormone acts as an antagonist to IGF-1, inhibiting its effects on
growth? a. Insulin b. Cortisol c. Thyroid hormone d. Growth hormone-inhibiting
hormone (GHIH)
17. What role does IGF-1 play in the development of insulin resistance? a. It
improves insulin sensitivity. b. It has no effect on insulin resistance. c. It promotes
insulin resistance. d. It regulates blood pressure.
18. During which physiological state is IGF-1 secretion reduced? a. Fasting b.
Exercise c. Sleep d. Stress
19. Which of the following is a consequence of IGF-1 deficiency in adults? a.
Increased bone density b. Muscle wasting c. Hyperactivity d. Enhanced cognitive
function
20. What is the primary factor influencing the release of growth hormone,
which subsequently stimulates IGF-1 production?
a. Blood glucose levels
b. Sleep patterns
c. Exercise
d. Nutritional status

Answers:
11. c
12. a
13. b
14. c
15. d
16. c
17. a
18. b
19. c