CERTIFICATE

This is to certify that this project is a bonafide work of

Arbind Kumar of Class XII F and has been
successfully completed and taken to be an issue
conducted by the CBSE in the session 2023-2024.

Internal Examiner External Examiner

ACKNOWLEDGEMENT
I would like to express my special thanks of gratitude
to my teacher Mr. Shouri Banerjee as well as our
principal Ms. Anindita Home Choudhury who gave
me the golden opportunity to do this wonderful
project which also helped me in doing a lot of
research and I came to know about many new things. I
am thankful to them.
 PROCEDURE

Step 1: Preparation of 1 litre of approximately N/10 solution of HCl by

diluting 10 ml HCl acid to 1 litre of water

Step 2: Preparation of 1 litre of approximately N/10 NaOH solution by

dissolving 4 grams of NaOH to make 14 litres of solution.

Step 3: Preparation of Na2CO3 solution by weighing exactly 1.325 grams

of anhydrous Na2CO3 and then dissolving it in water to prepare exactly
0.25 litres of 250 ml of Na2CO3 solution.

Step 4: Standardization of NaOH by titrating it against the standardized

HCl solution using phenolphthalein as indicator. The titration is to be
stopped once the pink colour of the solution disappears.

Step 5: Powdering the four antacid samples and weighing 1 gram of each.

Step 6: Addition of 25 ml of standardized HCl to each of the weighted

samples taken in conical flasks. The acid is taken in slight excess so that it
neutralises all the basic character of the tablet powder.

Step 7: Addition of few drops of phenolphthalein indicator and the

warming of the flask over a Bunsen Burner till most of the acid dissolves.

Step 8: Filtration of the insoluble material.

Step 9 : Titration of the solution against standardized NaOH solution till

permanent pink tinge is obtained.
 CALCULATIONS

 Standardization of HCl Solution:

Volume of 0.1 N Na2CO3 Solution taken = 20 ml
Indicator: Methyl Orange

S.No Volume of Na2CO3 Burette Reading (ml) Volume of acid Concordant

solution taken (ml) used (ml) Value (ml)

Initial Reading Final

Reading
1 20 0 16.9 16.9
2 20 16.9 34 17.1
3 20 0 17 17 17
4 20 17 34 17
5 20 0 17 17

Applying Normality equation:

N1V1 = N2V2
(acid) (base)

N1 x 17 = 0.1 x 20

 Normality of HCl, N1 = 2/17 = 0.11 = 0.1 (approx.)

  Standardization of NaOH Solution:
Volume of 0.1 N NaOH Solution taken = 20 ml
Indicator: Phenolphthalein

S.No Volume of NaOH Burette Reading (ml) Volume of Concordant Value

solution taken (ml) acid used (ml)
(ml)
Initial Final
Reading Reading
1 20 0 16.1 16.1
2 20 16.1 32.1 16
3 20 0 16 16 16
4 20 16 32 16
5 20 0 15.8 15.8

Applying Normality equation:

N1’V1’ = N2‘V2 ‘
(acid) (base)

0.11 x 16 = N2’ x 20

 Normality of NaOH, N2’ = (0.11 x 16) / 20 = 0.09 = 0.1 (approx.)

 THEORY

1.ENO

Eno is an over-the-counter antacid brand

produced by Glaxo Smith Kline. It is
basically an antacid combination that acts
locally in the stomach.

Composition:

oCitric acid anhydrous

oSodium bicarbonate
oSodium carbonate anhydrous

Reported side effects include restlessness, increase thirst, reduced

salivation, headache, possible hypotension and tachycardia.

Eno claims to provide fast relief from acidity in just 6 seconds. It

rapidly works on 6 signs of acidity like sour taste in mouth,
burning sensation in throat, chest and stomach, stomach
discomfort and heaviness.

2.DIGENE
Digene belongs to a group of
medicines called antacids,
manufactured by ABBOTT
INDIA LTD. It is used to treat
acidity, heartburn, indigestion,
gastritis (inflammation of the
stomach) and stomach upset. It is
also known to provide quick and
effective relief from gas troubles
such as bloating and belching. It
works by neutralizing the stomach
acid in the body.

Composition:
oMagnesium Hydroxide
oSimethicone
oMagnesium Aluminium Silicate Hydrate
oDried Aluminium Hydroxide Gel

Reported side effects include nausea, vomiting, headache,

stomach, pain, watery stools, and dizziness.
Digene is also sugar-free and is generally well tolerated.
Simethicone helps breakup gas bubbles in the gut. Aluminium and
magnesium antacids work quickly to lower the acid in the
stomach. Magnesium Hydroxide is laxative that increases water in
the intestine and reduced stomach acid. This medication works
only on existing acid in the stomach. It does not prevent acid
production.

ANALYSIS OF ANTACIDS
o Weight of antacid tablet powder = 1 gram

o Volume of HCl solution added = 60 ml

o Volume of sample solution taken for titration = 40 ml

 Observation:

I. 1 gram of ENO required 29 ml of NaOH to titrate it

completely.
II. 1 gram of Digene required 9 ml of NaOH to titrate it
completely.
III. 1 gram of Omez required 24 ml of NaOH to titrate it
completely.
IV. 1 gram of Gelusil required 22 ml of NaOH to titrate it
completely.

 Result:

Based on the hypothesis of the experiment , the antacid

which requires the least amount of NaOH is the best
antacid.
S.No Antacid Volume of NaOH used for
neutralizing unused HCl
1 Eno 29
 2 Digene 9
3 Omez 24
4 Gelusin 22

Therefore, the order of strength of the antacids is:

Digene > Gelusil > Omez > ENO
 BIBLIOGRAPHY

 NCERT Chemistry Book Class XII

 www. wikipedia.com