NEW AGE PUBLIC SCHOOL

CHAMPAPUKUR
Affiliated to the Council for the Indian School Certificate Examinations (CISCE)
Class - XII
Subject - Biology (863)
ISC Sample Question Paper
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Maximum Marks: 70
Time Allowed: Three hours
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This paper is divided into two sections – A and B.
Answer all questions.
Section – A consists of one question having sub-parts of one mark each.
Section – B consists of fifteen questions of two marks each.
The intended marks for questions or parts of questions are given in brackets [ ].
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Section A – 40 marks
Question 1.
Answer the following questions briefly:
1. How many ova and sperms would be produced from 50 primary oocytes and 50 primary
spermatocytes during gametogenesis? [1]
(a) 100 ova, 50 sperms
(b) 100 ova, 200 sperms
(c) 50 ova, 200 sperms
(d) 50 ova, 100 sperms

2. Which one of the following is a palindromic sequence? [1]

(a) 5'-CGTATG-3', (b) 5'-CGAATG-3',
3'-CGAATG-5' 3'-GCATAC-5'
(c) 5'-GAATTC-3', (d) 5'-CGAATG-3',
3'-CTTAAG-5' 3'-CTTAAG-5'

3. In E. coli the lac operon gets switched on when [1]

(a) lactose is present and it binds to the repressor
(b) repressor binds to operator
(c) RNA polymerase binds to the operator
(d) lactose is present and it binds to RNA polymerase

4. During spermatogenesis, the second maturation division results in the formation of: [1]
(a) 8 haploid spermatids
(b) 2 diploid spermatids
(c) 4 haploid spermatids
(d) 16 haploid spermatids

5. The abbreviation snRNA stands for: [1]

(a) Small nuclear RNA
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 (b) Small nucleus and RNA
(c) Small nucleolar RNA
(d) Sub-nuclear RNA

6. In industries, citric acid is obtained from which of the following the microbe? [1]
(a) Aspergillus niger
(b) Clostridium botulinum
(c) Saccharomyces cerevisiae
(d) Trichoderma polysporum

7. If the mother is homozygous for blood group B, and the father is heterozygous for blood group A,
their offspring will be of ___ and ___ blood groups: [1]
(a) A, B
(b) O, B
(c) B, AB
(d) A, AB

8. Which of the following statements is correct? [1]

(a) Down’s syndrome is caused due to trisomy of 22nd chromosome
(b) Haemophilia is an autosomal recessive disorder
(c) The life on the Earth appeared about 3.5 million years ago
(d) In angiosperms, the endosperm is triploid

9. Which of the following microbes is used in the production of Swiss cheese? [1]
(a) Aspergillus niger
(b) Mucor
(c) Monascus purpureus
(d) Penicillium notatum

10. If the sequence of nitrogen bases of the coding strand of DNA in a transcription unit is: [1]
5' – ATGAATG – 3', the sequence of bases in its RNA transcript would be:
(a) 5' – AUG A AUG – 3'
(b) 5' – UACUU AC – 3'
(c) 5' – CAUUCAU – 3'
(d) 5' – GUAAGUA – 3'

11. Some students wanted to investigate the pattern of inheritance of flower colour in snapdragon.
They selected some plants which were homozygous for red flowers and some other plants which
were homozygous for white flowers. These plants were labelled as Parental Plants (P1). These
plants (red-flowered and white-flowered), were cross-pollinated. The seeds obtained from these
plants were planted in a separate field. These seeds germinated to produce the plants which were
labelled as the plants of F1-generation.

Based on the above experiment, answer the following questions:

(i) Select the statement which correctly predicts the phenotype of the plants of F1 generation. [1]
(a) All the plants will bear red flowers
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 (b) All the plants will bear white flowers
(c) 50% plants will bear red flowers and 50% will bear white flowers
(d) 100% plants will bear pink flowers.

(ii) If the plants of F1-generation are allowed to self-pollinate, then in F2-generation [1]
(a) All of the resulting plants will have pink flowers.
(b) 75% plants will have red flowers and the remaining 25% plants will have white flowers.
(c) 25% plants will have red flowers, 25% plants will have pink flowers and 25% will have
white flowers.
(d) 25% plants will have red flowers and the remaining 75% plants will have white flowers.

(iii) The genotypic ratio of the plants of F2-generation will be: [1]
(a) 1: 2: 3
(b) 9: 3: 3: 1
(c) 1: 2: 1
(d) 3:1

(iv) This type of inheritance can be described as: [1]

(a) Polygenic inheritance
(b) Incomplete dominance
(c) Co-dominance
(d) Pleiotropism

(v) The biological name of snapdragon is: [1]

(a) Antirrhinum majus
(b) Pisum sativum
(c) Lathyrus odoratus
(d) Rhizobium leguminosarum

12. Assertion: - Autosomal disease is transferred from father to both son and daughter. [1]
Reason: - Autosomes are transferred only from father to son.
(a) Both assertion and reason are true, and reason is the correct explanation of assertion.
(b) Both assertion and reason are true, but reason is not the correct explanation of assertion.
(c) Assertion is true but reason is false.
(d) Both assertion and reason are false.

13. Assertion: - Mendel conducted his experiments on Pisum Sativum. [1]

Reason: - Pisum Sativum belongs the family Solanaceae.
(a) Both assertion and reason are true, and reason is the correct explanation of assertion.
(b) Both assertion and reason are true, but reason is not the correct explanation of assertion.
(c) Assertion is true but reason is false.
(d) Both assertion and reason are false.

14. Assertion: - Saheli, the new oral contraceptive for the females contains a steroidal preparation. [1]
Reason: - ‘Saheli’ is taken once in a week after initial intake of twice a week dose for 3 months.
(a) Both assertion and reason are true, and reason is the correct explanation of assertion.
(b) Both assertion and reason are true, but reason is not the correct explanation of assertion.
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 (c) Assertion is true but reason is false.
(d) Both assertion and reason are false.

15. Assertion: - After implantation, finger-like projections appear on the trophoblast called chorionic villi.
Reason: - Chorionic villi are surrounded by the uterine tissue and maternal blood. [1]
(a) Both assertion and reason are true, and reason is the correct explanation of assertion.
(b) Both assertion and reason are true, but reason is not the correct explanation of assertion.
(c) Assertion is true but reason is false.
(d) Both assertion and reason are false.
16. Study the diagram given below and answer the questions that follow:

(i) The alphabet ‘A’ represents ____ hormone: [1]

(a) Oestrogen
(b) Progesterone
(c) FSH
(d) LH

(ii) The alphabet ‘D’ represents ____ hormone: [1]

(a) Progesterone
(b) Oestrogen
(c) LH
(d) FSH

(iii) The structure marked ‘E’ is __: [1]

(a) Corpus luteum
(b) Secondary follicle
(c) Graafian follicle
(d) Corpus albicans

(iv) Ovulation occurs on day ______ of a typical menstrual cycle: [1]

(a) 12
(b) 14
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 (c) 22
(d) 28

(v) Menstrual cycle operates in ______ [1]

(a) All vertebrates
(b) All mammals
(c) Only primates
(d) Only apes

17. A woman has normal vision, but her father is colourblind. If she marries a colourblind man,
what is the probability of her son being colourblind? [1]

18. Name the toxin which is responsible for causing the symptoms of malaria. [1]

19. Mention the role of Azospirillum as biofertilizer. [1]

20. Explain the chromosomal theory of inheritance. [1]

21. What is colostrum ? [1]

22. What is the significance of LH surge through the menstrual cycle? [1]

23. Give the biological name of the causative agent of gonorrhoea. [1]

24. Expand the term ADA. [1]

25. If a segment of double-stranded DNA has 18% thymine, calculate the percentage of cytosine in the
DNA. [1]

26. Name the type of bioreactor which provides greater surface area for oxygen transfer. [1]

27. The presence of gill slits in the embryos of all vertebrates supports the theory of: [1]
(a) Recapitulation
(b) Organic evolution
(c) Metamorphosis
(d) Biogenesis

28. Bt cotton has been produced by transferring genes of _____ into the cotton plant. [1]
(a) Escherichia coli
(b) Pseudomonas putida
(c) Bacillus tumorigenes
(d) Bacillus thuringiensis

29. The enzyme ___ is used to remove the turbidity and clear the fruit juices: [1]
(a) Zymase
(b) Pectinase
(c) Amylase
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 (d) Papain

30. The enzyme pectinase is obtained from: [1]

(a) Bacillus aureus
(b) Bacillus cereus
(c) Trichoderma
(d) Claviceps

31. Identify the correct match from the columns and mark the correct option: [1]
A Leydig cells p Extra embryonic i ABP
mesoderm
B Primordial germ cell q Interstitial space ii Upto puberty no
development
C Spermatogonia r Germ cell of testis iii During embryonic
life
D Sertoli cell of testis s Nurse cell iv Testosterone

(a) A-q-iv, B-p-iii, C-r-ii, D-s-i

(b) A-s-iv, B-p-iii, C-q-ii, D-r-i
(c) A-q-i, B-r-ii, C-s-iii, D-p-iv
(d) A-q-iv, B-r-ii, C-p-i, D-s-iii

32. Match Column – I with Column – II and select the correct option from the choices given below: [1]

Column – I (Microbe) Column – II (Product)

(a) Saccharomyces cerevisiae Ethanol
(b) Monascus purpureus Lipase
(c) Clostridium Statins
(d) Penicillium Butyric acid

Matching codes:
(a) A-3, B-1, C-2, D-4
(b) A-1, B-4, C-3, D-2
(c) A-2, B-1, C-4, D-43
(d) A-4, B-3, C-2, D-1

SECTION B – 30 MARKS
Question 2.

(i) What is meant by lactational amenorrhoea? [1]

(ii) Discuss the physiological mechanism which makes lactational amenorrhoea a natural contraceptive
method. [1]

Question 3.

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A person in good health visited a garden where flowers were in full bloom. While returning from the
garden he suddenly started sneezing and wheezing. [2]
(i) Name and define the response of the person’s immune system in the abovementioned case.
(ii) Name the cell of the immune system and the type of antibody involved in this kind of response.

Question 4.

(i) Name the first human-like hominid ancestor. What was its cranial capacity? [1]
(ii) Name the hominid ancestor that existed about 1.5 mya. What was its cranial capacity? [1]

Question 5.

Briefly explain the role of the following in providing defense against infections in human body: [2]
(i) B-cells
(ii) T-cells

Question 6.

Give a technical term for the following: [2]

(i) The technique used to amplify a gene.
(ii) The technique used for early diagnosis of HIV infection.

Question 7.

Give any two differences between normal body cells and cancer cells. [2]

Question 8.

Name and describe the technique that helps in separation of DNA fragments. [2]

Question 9.

What is the role of a probe in recombinant DNA technology? [2]

Question 10.

What would happen to immune system, if thymus gland is removed from the body of a person ? [2]

Question 11.

A couple was expecting their child and visited a doctor for routine check-up. They came to know that the
foetus was suffering from an incurable disorder. The doctor advised them to go for MTP. [2]
(i) What is the full form of MTP?
(ii) Which diagnostic technique helped the doctor to detect the disorder in the embryo?

Question 12.

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The pedigree chart given below represents the pattern of inheritance of haemophilia in a family. Study it
carefully and answer the following questions: [2]

(i) What is the possible genotypes of members marked ‘5’ and ‘6’?
(ii) Assuming that member ‘14’ is heterozygous for haemophilia, what is the probability of the son of
this couple to be haemophilic?

Question 13.
The diagram of the organs of female reproductive system is given below. Study it carefully and answer the
questions that follow: [2]

(i) Identify the parts labelled as C and D.

(ii) Mention the functions of the parts labelled as A and B.

Question 14.

Define spermiogenesis. Where does it occur ? [2]

Question 15.

Observe the given diagram of a typical embryo sac in angiosperm and answer the following questions. [2]
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(i) Identify the parts labelled as 1 and 3.
(ii) Name the processes with which the parts labelled as 2 and 4 are involved.

Question 16.
Study the pedigree chart given below and answer the questions that follow. [2]

(i) Is the trait recessive or dominant? Give a reason for your answer.
(ii) Is the trait sex-linked or autosomal? Give a reason for your answer.