Apr 18, 2023 11:01:15 EDT

New England Journal of Medicine

Brody Foy

Discloser Identi er: 865113 Disclosure Purpose: 23-02892

Summary of Interests
I do not have any interests to disclose at this time.

Additional Questions
1. Are there other relationships or activities that readers could perceive to have in uenced, or that give the appearance of
potentially in uencing, what you wrote in the submitted work?

No.

2. What is the manuscript title?

The Adult Thymus is Critical for Health

3. Are you the corresponding author?

No.

Certi cation
I certify that the information provided in this disclosure is complete and accurate.
 May 10, 2023 10:12:33 EDT
New England Journal of Medicine
Karin Gustafsson

Discloser Identi er: 1087129 Disclosure Purpose: 23-02892

Summary of Interests
Company or Organization
Entity Type Interest Held By

Olive R Macdougall Fund Grant / Contract Self

Recipient Name: Karin Gustafsson Recipient Type: Individual

Grant / Contract Description: Research grant Grant / Contract Purpose: Research
Additional Information:

Vetenskapsrådet Grant / Contract Self

Recipient Name: Karin Gustafsson Recipient Type: Individual

Grant / Contract Description: Swedish Research Council International Postdoc Grant / Contract Purpose: Research
Award
Additional Information:

Intellectual Property
Type Is Licensed Interest Held By

Patent - Methods to enhance t cell regeneration - Self

Description: Methods to enhance t cell regeneration Patent Number: US20220143099A1

Patent Status: Pending Patent Holder: Current Institution
Filing Jurisdiction: USA
Licensees:
Additional Information:

Additional Questions
1. Are there other relationships or activities that readers could perceive to have in uenced, or that give the appearance of
potentially in uencing, what you wrote in the submitted work?

No.

2. What is the manuscript title?

The Adult Thymus is Critical for Health

3. Are you the corresponding author?

No.

Certi cation
I certify that the information provided in this disclosure is complete and accurate.
 May 09, 2023 12:54:31 EDT
New England Journal of Medicine
Kameron Kooshesh

Discloser Identi er: 1085532 Disclosure Purpose: 23-02892

Summary of Interests
Company or Organization
Entity Type Interest Held By

American Society of Hematology Grant / Contract Self

Recipient Name: Kameron Kooshesh Recipient Type: Individual

Grant / Contract Description: American Society of Hematology HONORS Award Grant / Contract Purpose: Research
Additional Information:

Additional Questions
1. Are there other relationships or activities that readers could perceive to have in uenced, or that give the appearance of
potentially in uencing, what you wrote in the submitted work?

No.

2. What is the manuscript title?

Health Consequences of Adult Thymus Removal

3. Are you the corresponding author?

No.

Certi cation
I certify that the information provided in this disclosure is complete and accurate.
 Jul 11, 2023 04:03:45 EDT
New England Journal of Medicine
David Scadden

Discloser Identifier: 9042 Disclosure Purpose: 23-02892

Summary of Interests
Company or Organization
Entity Type Interest Held By

Agios Pharmaceuticals, Inc. Other Self

Category: Other
Description: Director
Additional Information:

Clear Creek Bio Stock Self

Additional Information: Director

Craig Huff Family Gift Self

Description: philanthropy
Additional Information:

Editas Medicine Other Self

Category: Other
Description: Director
Additional Information:

Fate Therapeutics Stock Self

Additional Information:

Garuda Therapeutics Stock Self

Additional Information: SAB Co-chair

Gerald and Darlene Jordan Professor of Medicine Gift Self

Description: Gerald and Darlene Jordan Professor of Medicine Chair

Additional Information:

LifeVaultBio Stock Self

Additional Information: Director

Lightning Biotherapeutics Stock Self

Additional Information: Director

Magenta Therapeutics Stock Self

 Entity Type Interest Held By

Additional Information: Director

National Institutes of Health Grant / Contract Self

Recipient Name: David Scadden Recipient Type: Institution

Grant / Contract Description: U19AI149676 Grant / Contract Purpose: Research
Additional Information:

National Institutes of Health Grant / Contract Self

Recipient Name: David Scadden Recipient Type: Individual

Grant / Contract Description: U19AI149676 Grant / Contract Purpose: Research
Additional Information:

Simcere of America Consultant Self

Category: Consultant
Description:
Additional Information:

Sonata Therapeutics Stock Option Self

Additional Information: Director

VCanBio Consultant Self

Category: Consultant
Description: Scientific Advisory Board member
Additional Information:

Intellectual Property
Type Is Licensed Interest Held By

Patent - Methods to enhance t cell regeneration - Self

Description: Methods to enhance t cell regeneration Patent Number: EP3946440A1

Patent Status: Pending Patent Holder: Current Institution
Filing Jurisdiction:
Licensees:
Additional Information:

Patent - Bioengineered scaffolds for modulation of immune - Self

Description: Bioengineered scaffolds for modulation of immune system and the Patent Number: US20220047778A1
uses thereof Patent Holder: Current Institution
Patent Status: Pending
Filing Jurisdiction:
Licensees:
Additional Information:

Additional Questions
1. Are there other relationships or activities that readers could perceive to have influenced, or that give the appearance of
potentially influencing, what you wrote in the submitted work?

Yes.
 a. Please describe those relationships.

I am a founder, stockholder and director of a biotech company, Lightning Biotherapeutics, that is focused on improving
thymus function and regeneration.

2. What is the manuscript title?

Health consequences of adult thymus removal

3. Are you the corresponding author?

Yes.

a. Please list the other authors' names here.

Kameron A. Kooshesh, M.D., Brody H. Foy, D.Phil., David B. Sykes, M.D., Ph.D., Karin Gustafsson, Ph.D.

Certification
I certify that the information provided in this disclosure is complete and accurate.
 Apr 18, 2023 10:39:05 EDT
New England Journal of Medicine
David Sykes

Discloser Identi er: 1087128 Disclosure Purpose: 23-02892

Summary of Interests
I do not have any interests to disclose at this time.

Additional Questions
1. Are there other relationships or activities that readers could perceive to have in uenced, or that give the appearance of
potentially in uencing, what you wrote in the submitted work?

No.

2. What is the manuscript title?

The adult thymus is critical to health.

3. Are you the corresponding author?

No.

Certi cation
I certify that the information provided in this disclosure is complete and accurate.