Melhydran

by Beauty Creations
™

Natural goodies for the whole family

 Honey extract with water attracting
properties for skin
• Clinically demonstrated skin repair.
• Skin moisturization via NMF-like mechanism.
• Tested in rinse-off formulations against market benchmark.
• Healthy, caring, natural and nutritious.

Definition / Composition
Honey is produced by (honey) bees from the nectar of flowers. It is composed of sugars,
mainly fructose and glucose, and contains trace amounts of several vitamins and minerals.
Honey is a natural humectant, which means it attracts and retains moisture. It has been
used in beauty care routines already since ancient times. Cleopatra’s legendary milk and
honey baths are just one of many historical examples of women using honey to pamper
their skin. Queen Anne of England was reputed to use a honey and oil concoction to keep
her long hair lustrous, thick and shiny. Honey is a natural ingredient with a healthy, nutritious
image that fits very well into the market trend of natural products that is now as popular
as ever.

MELHYDRAN™ is based on honey extract, obtained by gentle purification of natural honey.

Rich in oligosaccharides, organic acids, amino acids and minerals, it has NMF-like and
water attracting properties, providing moisturization and care to skin. Its healthy and
soothing image make it suitable for a wide range of rinse-off and leave-on applications,
including baby care.
Melhydran™ contains all the wholesome components of honey in a stable and easy to
formulate form, to be used for the benefit of skin and hair in personal care formulations.

INCI name
Melhydran™ LS 9876: Water (and) Butylene Glycol (and) Honey Extract (and) Glycerin (and)
Urea.

Cosmetics use
• Personal care products with honey claim.
• Cosmeto-food products.
• Moisturizing skin and hair care.
• Baby care and sensitive skin type products.

Dosage / Solubility
1. Dose of use:
Melhydran™ LS 9876: 1 - 5%.
2. Solubility:
Soluble in water, insoluble in oils and fats.

Analytical characteristics
1. Aspect:
Melhydran™ LS 9876: pale yellow liquid with a characteristic odor.
2. Preservative: none.
Efficacy tests
Moisturizing activity on human horny layer
- dielectric conductivity
Moisturizing effect of MELHYDRAN™ at 5% compared to placebo.
Dielectric conductivity (µS)
200 Protocol
Human skin

Stratum corneum
150
44% RH

(**)
Conductivity measurements
100 (**)
Treatment
(**)
(**) Treatment with hydrogel
(**) Control without Treatment with containing 5%
(**) treatment placebo hydrogel MELHYDRAN ™
50

1 mg/cm2 dose 3 times (0, 30 and 60 minutes)

0 Conductivity measurements up to 24 hours

Before 30 mn 1 hour 2 hours 4 hours 6 hours 24 hours

Control without treatment

Statistics:
Placebo hydrogel Mean of 8 assays ± SEM
1 factor ANOVA
Hydrogel containing 5% Test a posteriori:
Melhydran™ PLSD of Fischer
(**) significant / control
and placebo (p < 0.01)

Melhydran™ has a a significant and a long-lasting moisturizing effect in comparison to

placebo.

Improvement of the skin microrelief

(clinical study on volunteers with very dry skin)

Before
treatment

After treatment
with 5% Melhydran™

SEM images of skin microrelief.

Complementary test:
• Moisturization (ex vivo). Significant 24 hr. moisturization with a gel containing 5% Melhydran™.
• Hydro-retention on hair (clinical study). The hair washed with a shampoo containing 2% or
5% Melhydran™ is able to retain moisture under low relative humidity conditions better than
shampoo containing 5% glycerin.

After 4 weeks of treatment with a gel containing 5% Melhydran™, the skin microrelief has
been restored: the skin is well hydrated and the skin surface is much smoother.
Skin is well moisturized due to the water attracting properties of Melhydran™.
EUROPE
BASF Beauty Creations
49, avenue Georges Pompidou
92593 Levallois-Perret Cedex
FRANCE
Tel: +33 (0) 1.49.64.53.97
Fax: +33 (0) 1.49.64.53.85
bcs-europe@basf.com

AMERICAS
Beauty Creations
BASF Corporation
50 Health Sciences Drive
Stony Brook, NY 11790
USA
Tel: +1 (631) 380 2300
Fax: +1 (631) 689 2904
bcs-northamerica@basf.com

JAPAN & ASIA-PACIFIC

BASF Japan Ltd.
21F Roppongi Hills Mori Tower,
6-10-1 Roppongi, Minato-ku,
Tokyo, 106-6121
JAPAN
Tel: +81 (0) 3-3796-9214
Fax: +81 (0) 3-3796-9299
bcs-asia@basf.com

Edition March 6, 2013

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are believed to be accurate and reliable, they are presented
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results obtained by use of the products or application of
the suggestions described are assumed by the user. THERE
ARE NO WARRANTIES OF ANY KIND. ALL EXPRESS AND
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suggestions concerning possible use of the products are
made without representation or warranty that any such use
is free of patent infringement and are not recommendations
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toxicity data and safety measures are indicated or that other
measures may not be required. The claims and supporting
data provided in this publication have not been evaluated for
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and the results reported may not be generally true under
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