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principles of medical laboratory science

nu mwa | 1st semester midterm 2023-2024 | tinetine :p

OVERVIEW OF THE MEDICAL medical laboratory procedures of technic


TECHNOLOGY/MEDICAL LABORATORY which will aid the physician in the diagnosis
SCIENCE PROFESSION strictly and treatment of disease and in the
promotion of health in general.
OUTLINE
What is common among them?
● Historical Perspective
- Performing laboratory procedures
● Medical Technology/Medical Laboratory
(samples)
Science Practices
- Analysis (results)
● Medical Technology Education
- Diagnosis and treatment (disease)
LEARNING OUTCOMES
CLINICAL LABORATORY
● Trace the history of Medical Technology
Globally and in the Philippines.
● Enumerate the scope of Medical Technology It is a facility that performs chemical and microscopic
Practices. examinations of various body fluids (e.g. blood
● Discuss the scope of medical technology tissues).
curriculum and different job opportunities. Inside the Clinical Laboratory
- Pathologist
MEDICAL TECHNOLOGY - Medical Technologist
is also known as: - Medical Technician
Clinical Laboratory Science
Medical Laboratory Science Medical Technologist acts as…
MEDICAL DETECTIVES
What is Medical Technology (according to) ?
Roles of Medical Technologist
Ruth Heinemann
- is the application of natural, physical and ● Observe, identify, and analyze organisms
biological sciences to the performance of and cells causing infection and disease.
laboratory procedures which aid in the ● Perform blood tests.
diagnosis and treatment of disease. ● Measure substance in blood and other body
fluids.
Anne Fagelson ● Operate complex apparatus, instruments
- is the branch of medicine concerned with the and machines.
performance of laboratory determinations ● Use standards and controls to improve
and analyses used in the diagnosis and reliability of results.
treatment of the disease and maintenance of ● Work under pressure with accuracy and
health. precision.
● Adhere to high ethical standards of
Walters performance.
- is the health profession concerned with
performing laboratory analyses in view of HISTORY OF MEDICAL TECHNOLOGY
obtaining information necessary in the GLOBAL AND LOCAL
diagnosis and treatment of disease as well
as in the maintenance of good health. EARLY BEGINNINGS

RA 5527 (The Philippine Medical Technology Act 400 B.C.


of 1969) - Hippocrates (Father of Medicine) described
- is an auxiliary branch of laboratory medicine the “four humors” in man; BLOOD,
which deals with the examination of tissues, PHLEGM, YELLOW BILE and BLACK
secretion and excretion of human body and BILE
body fluids by various chemical, - Urine was regarded as composite of these
microscopic, bacteriologic and other humors.
principles of medical laboratory science
nu mwa | 1st semester midterm 2023-2024 | tinetine :p

- William Pepper Laboratory was also


600 B.C. opened at the University of Pennsylvania.
- Hindu physicians recorded the sweet taste
of diabetic urine as well as polyuria in 1908
diabetes. - Dr. James C. Todd wrote “A Manual of
Clinical Diagnosis” which became the
1500 B.C. standard reference for laboratories.
- Vivian Herrick identified Taenia and
Ascaris. 1921
- “Ebers Papyrus” was discovered. - Denver Society of Clinical Pathologists
- “Ebers Papyrus” – the oldest preserved was organized.
Egyptian compilation of medical texts. - American Board of Pathology was
organized in 1936.
1632
- Anton Van Leeuwenhoek invented the World War I
compound microscope. - Produced a great demand for technicians.
- He was the first to describe the red blood - University of Minessota is one of the first
cells, protozoa, and to classify bacteria schools to establish trainings for workers in
according to shape. 1922 and first to offer degree program in
1923.
1628-1694
- Marcelo Malphigi (Founder of Pathology) World War II
- Greatest of the early microscopists. - “Closed system” of blood collection was
- Contributed to Embryology and Anatomy. adopted.
- Advanced instrumentation.
1847 - Automated equipment.
- Rudolph Virchow - Quality control programs.
- Founder of the “Archives of Pathology” in
Berlin. IN THE PHILIPPINES

1848 Jan. 9, 1945


- Herman Fehling - First Clinical Laboratory in Phil. at
- Performed the first quantitative test for Quiricada St., Sta. Cruz, Manila ws
urine sugar. established and is known as Public Health
Laboratory.
15th Century
- Discovery of dyes (aniline dyes) made Oct. 1, 1945
possible the staining and study of - Dr. Pio de Roda and Dr. Mariano Icasiano
microorganisms such as bacteria. reopened Manila Public Health Laboratory.

IN THE UNITED STATES 1947


- Dr. Pio de Roda and Dr. Prudencia Sta.
1878 Ana offered a training for highschool and
- Dr. William H. Welch paramedical graduates.
- Established a laboratory at Bellevue
Hospital Medical College. 1954
- Became the first professor of Pathology at - 6-month laboratory training was offered.
John Hopkins University (1885). - Formal education of Medical Technology
began.
1896
- Dr. William Osler opened the first clinical
laboratory at John Hopkins Hospital. IN THE UNITED STATES
principles of medical laboratory science
nu mwa | 1st semester midterm 2023-2024 | tinetine :p

HISTORY OF MEDICAL TECHNOLOGY in different sections during the 4th level in a


EDUCATION IN THE PHILIPPINES CHED-accredited training laboratory.
- A licensure examination is given to all
MRS. WILLA HILGERT HEDRICK applicants for registration as Medical
Founder of Medical Technology Education in the Technologist.
Philippines
Program Goals
1954 The program aims for the graduates to:
- Philippine Union College of Baesa - Develop knowledge, skills, professional
- First to offer BS Medtech. attitude and values in the performance of
- Dr. Jesse Umali was its first graduate after 2 laboratory procedures.
years. - Acquire critical thinking skills.
- Engage in research and community-related
1957-1959 activities.
- Dr. Antonio Gabriel and Dr. Gustavo - Participate in activities promoting the
Reyes of UST offered MT as an elective to profession and engage in the life-long
pharmacy students. Due to its popularity, it learning undertakings.
was decided to be offered as a course. - Develop collaborative and leadership
qualities.
1960
- CEU offered MT course Expected Performance Outcomes of Graduates
- First batch graduated in 1962. The graduates must be able to:
- Demonstrate technical competence in the
1662-1662 performance of clinical laboratory tests.
- Dr. Horacio Ylagan and Dr. Serafin - Demonstrate analytical and critical
Juliano applied for the offering of BSMT thinking skills in the workplace.
courses in FEU which was approved in - Engage in the proper collection, analysis
1662. and projection of health information.
- First batch graduated in 1663. - Demonstrate interpersonal skills, leadership
qualities and ethical practice of the
U.P – offers the same course but the degree is profession.
conferred to as B.S. Public Health. - Apply research skills in relevance to areas
to areas of Medical Technology/Laboratory
Professional Organizations of Medical Technology Science practice.
in the Philippines: - Participate in community oriented
- The Philippine Association of Schools of activities.
Medical - Engage in life-ling learning activities.
- Technology and Public Health, Inc. - Demonstrate effective teaching and
(PASMETH) communication skills.
The Philippine Association of Medical Technologists
(PAMET) Program Curriculum
The Course shall be at least four years,
MEDICAL TECHNOLOGY EDUCATION IN including a 12-month long internship in accredited
laboratories and shall include the following subjects:
THE PHILIPPINES
GENERAL EDUCATION
CORE COURSES
Nature of the Field of Study PROFESSIONAL COURSES
Program course shall be called as:
- Bachelor of Science in Medical Technology Scope of Licensure Examination
- Bachelor of Science in Medical Laboratory The given examination covers the following subjects
Science with its specific percentage:
- It is a four year program consisting of a Clinical Chemistry 20%
one year internship with rotational duties
principles of medical laboratory science
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Microbiology and Parasitology ● Justify and explain various information on a


20% laboratory requisition.
Hematology ● Identify the different phases of laboratory
20% testing.
Blood Banking and Serology 20%
Clinical Microscopy 10% CLINICAL LABORATORY
Histopathologic Techniques and MT Laws ● Facility
● Specimens (whole blood, serum, plasma,
10%
urine, stool, etc.) from the human body
● Collected, processed, examined or analyzed
● Prevention, diagnosis, and treatment
Employment Opportunities of Medical
Technology Graduates CLASSIFICATION OF CLINICAL
● Medical technologist (generalist/specialist) LABORATORY
● Clinical laboratory supervisors
● Chief medical technologist DEPARTMENT OF HEALTH
● Laboratory owners Administrative Order no. 20017-0027
● Sales and public relations representative
● Educational representatives (company/health A. Based on ownership
program) 1. Government
● Researcher (industrial/medical) 2. Private
● Teachers/Instructors (secondary/tertiary
levels) B. Based on Function
● Employment abroad 1. Clinical Pathology
2. Anatomical Pathology
(Medical Technologist Specialist, Phlebotomist, Clinical Pathology:
Industrial/Medical Researcher, Medical Doctors, 1. Clinical Chemistry
Medical Sales Representatives) 2. Hematology
3. Microbiology
UNIT 2 4. Clinical Microscopy
CLINICAL LABORATORY 5. Immunology
6. Molecular Biology
7. Immunohematology
8. Cytogenetics
OUTLINE
9. Endocrinology
● General overview
10. Toxicology
● Classification of medical laboratories
11. Therapeutic drug monitoring
● Organization of the laboratory
Anatomical Pathology:
● Laboratory Sections
1. Surgical Pathology
● Information flow in the clinical
2. Immunohistopathology
laboratory
3. Cytology
● Three phases of the laboratory testing
4. Autopsy
● Laboratory policies
5. Forensic Pathology
6. Molecular Pathology
LEARNING OUTCOMES
● Identify and differentiate the classification
C. Based on Institutional Character
of clinical laboratory settings.
1. Institution-based
● Construct an organizational
2. Freestanding
chart/architectural plan.
● Explain the roles, functions and services
D. Based on Service Capability
offered by the different sections of the
1. General Clinic Laboratory
laboratories.
2. Special Laboratory
principles of medical laboratory science
nu mwa | 1st semester midterm 2023-2024 | tinetine :p

General Clinical Laboratory


a. Primary Category
1. Routine hematology (CBC) LABORATORY SECTIONS
2. Qualitative platelet determination
3. Routine urinalysis and fecalysis A. SPECIMEN PROCESSING
4. Blood typing – for hospital-based B. HEMATOLOGY SECTION
b. Secondary Category C. COAGULATION SECTION
1. Routine clinical chemistry D. CLINICAL MICROSCOPY
2. Quantitative platelet determination E. PARASITOLOGY
3. Cross matching F. CLINICAL CHEMISTRY
4. Gram staining G. CLINICAL MICROBIOLOGY
5. KOH staining for fungal disease H. IMMUNOLOGY/SEROLOGY
c. Tertiary Category SECTION
1. All secondary lab services SEROLOGY TESTS
2. Special chemistry (Cardiac markers) ● Pregnancy test – detects B-HCG
3. Special hematology (coagulation tests) ● Dengue Test
4. Immunology/Serology (HIV, hepa ● HbsAg – for hepatits
profile, tumor markers) ● Bacterial Agglutination test
5. Microbiology – culture of sensitivity a. Widal test –typhoid fever
d. Limited Service Capability b. Weil-Felix – nonspecific test for
Special Clinical Laboratory typhus fever
a. Assisted reproduction technology laboratory I. IMMUNOHEMATOLOGY/BLOOD
b. Molecular and cellular technology BANK
c. Molecular pathology, Forensic pathology, and J. HISTOPATHOLOGY/
Anatomic laboratory CYTOPATHOLOGY

E. National Reference Laboratory Why is Laboratory Testing Performed?


1. Confirmatory testing 1. To assign a diagnosis
2. Surveillance **confirm clinical diagnosis
3. Resolution of conflicting results **to establish an appropriate plan of
4. Training and research action
5. Evaluation of diagnostic kits and reagents 2. Prevention by early detection of diseases
through screening tests.
F. Satellite Testing Sites 3. Ongoing assessment of the patient’s
● Testing site owned by a licensed laboratory progress and treatment.
but situated in a location some distance from
the main laboratory. INFORMATION FLOW IN THE CLINICAL
LABORATORY
G. Mobile Clinical Laboratories
● Laboratory testing unit
● Moves form one testing site to another ❖ Laboratory requisition
testing site ⮚ A form used by physician to document the
● Has a temporary testing location tests that are to be performed on patients.
● Shall have a base laboratory ⮚ Contains the following
● Permitted to collect specimen only ✔ Patient’s demographic data, name data,
● Operate within a 100-km radius from its address, birth data
main lab ✔ Test selection – should be marked clearly
✔ Date and time of collection
ORGANIZATION OF THE LABORATORY ✔ Identification of the person who
……. performed the collection, name of
ordering physician
✔ Additional comments
principles of medical laboratory science
nu mwa | 1st semester midterm 2023-2024 | tinetine :p

❖ Laboratory Directory ⮚ Responsible Personnel


⮚ Stability of the specimen ***Medical Technologist, Section
⮚ Minimum volume Supervisor, Chief Medical Technologist,
⮚ Test schedule office clerk or staff
⮚ Specimen processing
⮚ Method LABORATORY POLICIES

LABORATORY REPORTS A. Laboratory hour and emergency work


⮚ to transmit test results ● Definite working hours
⮚ Reference rangers ● Outside regular working hours organize a
⮚ Date and time of the specimen collection system for testing urgent specimens.
⮚ Name, address of the laboratory
⮚ Name and identification number of B. Range of tests to be performed and those to
patient be referred to higher level
⮚ Source of specimen ❖ Range of tests to be performed
⮚ Date and time the report was generated 1. The number of staff available
2. The availability of material
THREE PHASES OF LABORATORY TESTING resources
3. The types of health institutions
A. PREANALYTICAL PHASE (hospital or health center)
❖ occurs first in the laboratory process ❖ Referral of specimens (when
⮚ Patient preparation necessary)
⮚ Paper work and data entry Example specimens for HIV
⮚ Specimen collection, processing, storage, detection and water samples for
and transportation bacteriological analysis.
⮚ Responsible Personnel
***Phlebotomist, laboratory technician C. Collection of laboratory specimen
1. The specimen containers should be clearly
B. PREANALYTICAL PHASE labeled with the patient’s name,
❖ Considered the “actual” laboratory testing or identification number, date of collection and
the diagnostic procedures, processes and time of collection
products 2. A fully completed request form should
⮚ Proper instrument maintenance accompany each specimen with the detail
⮚ Reagent supplies mentioned above.
⮚ Quality control
⮚ Responsible Personnel D. Workload capacity of a laboratory
***Medical Technologist or Medical Lab - Should match to the number of staff
Scientist - Their level of training
❖ Ensure accuracy, precision, reliability - Size of the laboratory
of the test procedure - The availability of laboratory facili
❖ Validates the following:
⮚ Test reagents/kits
⮚ Testing process
⮚ Training of the lab personnel
performing the test

C. POST-ANALYTIC PHASE
❖ Includes the following:
⮚ Review and analysis of results
⮚ Recording and reporting of test results
⮚ Storage and disposal of specimen
⮚ Releasing of results

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