Tissue Embedding Center

BK-TEI/TEV
BK-TECPV
BK-CPIV
User Manual

JINAN BIOBASE MEDICAL CO.,LTD.

Version 2023.03
 Preface
Dear customers:
Thanks for choosing JINAN BIOBASE MEDICAL CO.,LTD. Products!
We sincerely hope that our products can bring the greatest help to your work.
● When using this machine for the first time, please read this manual carefully!
● This product may only be operated by trained and authorized personnel.
● The maintenance of the equipment can only be done by the company or the dealer authorized by
the company.
● If the operator encounters problems not mentioned in this manual, please contact our company or
our authorized dealer to ask for the correct solution.
● The machine must be inspected and maintained within the specified time.
After reading the manual, please keep this manual in a convenient place for easy reference at any
time.

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 Content

Preface ................................................................................................................................................... 1
Content ...................................................................................................................................................2
1. Overview ............................................................................................................................................3
2. Scope of Application ..........................................................................................................................3
3. Working Environment ........................................................................................................................3
4. Technical Parameters ......................................................................................................................... 3
5. Features ..............................................................................................................................................5
5.1 Appearance ................................................................................................................................5
5.2 Function .................................................................................................................................... 5
6. Structure Description ......................................................................................................................... 7
6.1 Main structure ........................................................................................................................... 7
6.2 Control panel indication ............................................................................................................7
7. Operation ........................................................................................................................................... 8
7.1 Wax melting .............................................................................................................................. 8
7.2 Temperature setting ...................................................................................................................9
7.3 Timing calibration .....................................................................................................................9
7.4 Timing .......................................................................................................................................9
7.5 Tissue embedding center control software ..............................................................................10
8. Notes ................................................................................................................................................ 10
9. Maintenance ..................................................................................................................................... 11
10. Inspection before power-on after unpacking ................................................................................. 13
11. Warranty .........................................................................................................................................14
12. Storage and Transportation ............................................................................................................ 14

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 1. Overview
The Tissue Embedding Center is composed of a control system, a wax melting system and a cooling
system. It is used for paraffin embedding of dehydrated tissues before pathological analysis. It is
mainly used for tissue wax embedding, rapid wax fixation, and frozen fixation of frozen embedded
tissue after the specimen is dehydrated and waxed, It can be used by medical institutions and medical
colleges for teaching, pathological research and diagnosis, quarantine, food inspection and other
departments.

2. Scope of Application
The Tissue Embedding Center is suitable for paraffin embedding of dehydrated tissue before
pathological analysis.
It can be used by medical institutions and medical colleges for teaching, pathological research and
diagnosis, quarantine, food inspection and other departments.

3. Working Environment
Ambient temperature: 0～30℃
Relative temperature: ≤85%
Atmospheric pressure: 86～106kpa

4. Technical Parameters
Model BK-TEⅠ BK-TEV
Wax tank capacity 3L 8L
Storage table temperature 0～80℃ RT～80℃
Wax bath temperature 0～80℃ RT～80℃
Left storage box temperature 0～80℃ RT～80℃

Right storage box temperature 0～80℃ RT～80℃

Workbench temperature 0～80℃ RT～80℃
Flow wax tube temperature 0～80℃ RT～80℃
Freezer temperature control range / /
Temperature control accuracy ±3℃ ±3℃
Small cold table temperature / ≤-5℃
Storage box size 200×105×60mm 240×240×57mm
Working table size 180×120 (mm) 700×93 (mm)
Small cold table size / 69×59 (mm)
Freezer table size / /
Power supply AC 220V～240V AC 220V～240V
Power frequency 50Hz/60Hz 50Hz
Consumption 500W 1100W

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 Dimensions 550×525×420(mm) 735×692×400.5(mm)

Model BK-TECPV
Wax tank capacity 8L
Storage table temperature 55℃～80℃
Wax bath temperature 55℃～80℃
Left storage box temperature 55℃～80℃

Right storage box temperature 55℃～80℃

Workbench temperature 55℃～80℃
Flow wax tube temperature 55℃～80℃
＋5～－20℃（Temperature
control mode）；The lowest
Freezer temperature control range
temperature can reach -28℃
（Super cooling mode）
Temperature control accuracy ±1℃
Small cold table temperature ﹤-5℃
Storage box size 239×239×57mm
Working table size 700×93 (mm)
Small cold table size 69×59 (mm)
Freezer table size 300×360 (mm)
Power supply AC 220V～240V
Power frequency 50Hz
Consumption 1100W/300W

735×692×400.5(mm)
Dimensions
631×350×400.5 (mm)

Model BK-CPⅣ
＋5～－20℃（Temperature control
Freezer temperature control range mode）；The lowest temperature can reach
-28℃（Super cooling mode）
Temperature control accuracy ±1℃
Freezer table size 300×360 (mm)
Power supply 220V～240V
Power frequency 50Hz

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 Consumption 300W

Dimensions
631×350×400.5(mm)

5. Features
5.1 Appearance
The machine adopts the split structure that is popular in the world: the embedding body and the
freezing table body can be used in combination or separately, thus avoiding the mutual interference
of temperature. The display screen adopts LCD Chinese menu display screen, the handwriting is
clear, the displayed data can be clearly observed at any angle, the interface distribution is reasonable,
and the operation is simple.
The wax tank adopts the integrated structure of the cylinder valve body, and the heating device is
cast as a whole. The heating temperature of the cylinder body is uniform and the performance is safe
and reliable, which improves the safety and reliability of the machine.
The flow wax control is controlled by two methods: micro switch and foot switch. The operator can
choose according to his own operating habits, which is suitable for batch tissue embedding work.
Bilateral porous tweezers storage heating table design, can place large and small tweezers, and can
be heated, making the embedding operation more convenient. A magnifying glass mounting base is
reserved, and users can configure a movable magnifying glass as needed, which is convenient for
handling extremely small specimens.
The workbench is equipped with a residual wax recovery device, which is convenient for residual
wax cleaning.
The enlarged left and right boxes, the inner box and the outer box are separated, suitable for all kinds
of dehydration baskets, easy to remove wax, replace and maintain. Drawer-free design, automatic
recycling of residual wax, easy maintenance.

5.2 Function
The paraffin tank adopts double overheating protection, which is safe and reliable. The two-stage
filtration design can effectively avoid paraffin blockage, and the large capacity ensures that a large
number of tissue embeddings can be completed at one time.
The micro switch and foot switch with manual operation sensitivity are optional for the operator.
Paraffin gravity backflow design, automatic recovery of residual wax, high-performance solenoid
valve control, to prevent paraffin overflow. Two-stage paraffin precipitation filtration, no blockage,
leakage and wax dripping phenomenon.
Equipped with a universal metal hose magnifying glass and LED light-emitting tube mounting base,
the illumination angle can be adjusted arbitrarily, which is more convenient for observing tissue
samples and determining the location of small tissue embedding.
This machine has 5 independent temperature control systems, among which the temperature of wax
tank, wax flow nozzle, worktable, storage tank and storage tweezers heating table can be adjusted
arbitrarily within the range of RT~80℃. The new flexible heating element is adopted, which has fast

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heating, uniform heating, and reliable energy saving.
With automatic power-on function, you can set different power-on time every day.
There are two modes of operation, the manual mode starts and stops immediately, and the automatic
mode has the function of power-off memory and self-start function when incoming calls. The whole
machine has a delay function, which can be set to delay the switch on and off time, and can also start
the whole machine at any time.
The freezing table adopts the original imported condenser, and adopts imported environmentally
friendly fluorine-free refrigerant, which has excellent cooling effect. The freezing table has super
cooling mode and temperature control mode, and the temperature control accuracy is high.
Semiconductor random small cold stage, instant refrigeration, convenient for quick positioning and
embedding of specimens, and improve work efficiency.
5.3 Use period: 5 years under normal operation. See label for production date.
5.4 There are no special applicable groups and no special contraindications.

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 6. Structure Description
6.1 Main structure
The machine consists of control system, wax melting system and cooling system, controlled by
single chip microcomputer, mainly including wax tank, heat preservation tank, electric control nozzle,
temperature control table, heating device and other parts.

1. Control panel 2. Cooling plate display 3. Cooling plate 4. Left insulation box 5. Workbench
6.Wax nozzle 7. Heating table for storage tweezers 8. Insulation box

6.2 Control panel indication

6.2.1 Schematic diagram of Tissue Embedding operation panel

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 Operation panel diagram
1. Display screen 2. Confirm key 3. Adjustment key 4. Timing key 5. Setting key 6. Power key
Display screen: display the working status of the working interface
Confirm key: Adjust the parameters to confirm.
Adjustment key: Up, down, left and right keys are used to adjust various parameters.
Timing key: used to control the working state and the opening and closing of the timing function.
Setting key: used to switch between the main interface and the setting interface.
Power key: used to control the working state of the embedding machine and the opening and closing
of the screen
6.2.2 Schematic diagram of the front panel of the Tissue cooling plate

Temperature setting interface

1. Actual temperature display 2. Setting button 3. Decrease button 4. Increase button

7. Operation
7.1 Wax melting
First, put an appropriate amount of wax into the wax tank, and never fill the wax tank; Turn on and
connect the power supply, connect the AC220V power supply with the rear panel power socket with
the power cord, press the power switch, and the front switch of the refrigeration table must also be
turned on. The red light of the switch is on, and the power is on. For the convenience of users,
according to the commonly used values, the temperature of the five heating zones of the instrument
has been preset as: 55 ℃ for the left box, 70 ℃ for the wax nozzle, 65 ℃ for the wax cylinder,
55 ℃ for the workbench, and 55 ℃ for the right box. If the user thinks it is inappropriate, the
temperature can be set again. If it is appropriate, press the "Start/Stop" button directly to enter the
working state.

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7.2 Temperature setting
When using the embedding machine, the temperature of five working areas should be set first. The
specific operation is as follows: set when the "start/stop" light is off. For example, press the "Save
box" button. Each time you press the button, the temperature will increase by 5 ℃ , and the light
corresponding to the temperature number will be on. It will cycle from 55 ℃ to 70 ℃ . The
temperature setting method for other working areas is the same. When a certain working area is
required not to be heated, the light in the working area can be set to be completely off. For example,
if the workbench is required not to be heated, press the workbench key to make its corresponding
light completely off. Press the "Start/Stop" key, the "Start/Stop" light will be on, the working area
will start heating, the temperature indicator light tube will change from "green" to "red", and "red"
means heating, reaching the set temperature, from "red" to "orange". The temperature indicator light
tube represents the following states: "red" means heating, "green" means setting state, and "orange"
means reaching the set temperature insulation state.
The set temperature is automatically stored in the computer chip and has the memory function. If you
do not want to reset the temperature when you use it again, press the "Start/Stop" key to heat.
Refrigeration table temperature setting: press the setting button to enter the temperature setting
interface, and then press+or - to adjust the rise or fall of the set temperature. After adjustment, press
the setting button again to indicate that the temperature setting is complete and enter the actual
temperature display interface.

7.3 Timing calibration

Press the timing key for more than 3 seconds to release, and the instrument will enter the setting state
when the week light is "on". Press the "increase" or "decrease" key, and the week will operate from 1
→ 7 or 1 ← 7, and the corresponding week × The light is "on" after weekly setting.
Press the "time calibration" key to enter the "hour" setting. The "hour" light is "on" and "00" is
displayed. Press "increase" or "decrease", and the hour will cycle from 0 → 23 or 0 ← 23.
Press the "Timing" key to enter the "minute" setting. At this time, the "minute" light is "on" to
display "00". Press "Increase" or "Decrease" to cycle from 0 → 59 or 0 ← 59.
Press the "time calibration" button to complete the time calibration. At this time, the weekly, hourly
and minute lights are all off.
For example, today is 12:10 on Saturday. Press the "Time Calibration" key for more than 3 seconds
to release it, and the "Week" light will be on. The "Monday" light will be on. Press the "Increase" or
"Decrease" key until "Saturday" light will be on. Press the "Time Calibration" key and the "hour"
light will be on. Press the "Increase" or "Decrease" key to display "00" until "12". Press the "Time
Calibration" light will be on, and the "00" light will be on. Press the "Increase" key to display "10".
Press the timing key to complete the timing.

7.4 Timing
Press the "Timing" key for more than 3 seconds to release, and the timing light "on" will enter the
timed startup setting state, and the "Week" light will be on. Press the "Increase" or "Decrease" key,
and the week will cycle from 1 → 7 or 1 ← 7, and the corresponding week × The light is on and
the weekly setting is completed; Press the time key to enter the time setting. The time light is on. The
time and minute setting method is the same as above. Press the timing key to confirm, the timing

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light is off, and the setting is completed.
Note: If the power-on time of the day is set to 0:00, it means that the day will not be powered on.
For example, the embedding machine is required to start automatically and regularly at 7:00 on
Tuesday morning.
Press the timing key, the timing light will be on, the "week" light will be on, and the previous
Monday's timing start time will be displayed. Press the "increase" key, the Tuesday light will be on,
and press the timing key to confirm. When setting, the "hour" light will be on at this time. Press the
"increase" or "decrease" key to 7 o'clock, press the "minute" light of the timing key, and the "00"
point will be displayed. Press the timing key to confirm, the timing light will be off, and the setting is
complete.

7.5 Tissue embedding center control software

The complete version of software is BMJ-LCD-V1.2.0,
Software release version: BMJ-LCD-V1
The naming rule of software version is: "BMJ-LCD-V1" refers to the released version of the
embedding machine software, which is a major enhancement software update, where "BMJ"
represents the acronym of the Chinese pinyin of the word "embedding machine", "LCD" represents
the product model of the liquid crystal display embedding machine, and V1 represents the version
serial number of the major update of the software; "0" means slightly enhanced software update; "0"
indicates the correction software update.
Operating environment: hardware configuration: the processor is Italian Semiconductor (ST)
STM32F103VET6; The memory is AT24C1024; I/O equipment is touch button; The display is liquid
crystal display. The software environment is Keil uVision4, without network conditions.

8. Notes

After the instrument arrives, open the box to check the appearance, and accept the random
accessories. Please read the instruction manual carefully before starting the operation.

To ensure personal and equipment safety, the machine must use a three-wire power supply,
and ensure that the instrument is reliably grounded. It is forbidden to use a power supply without a
ground wire or a ground wire.

Before starting the machine, an appropriate amount of medical paraffin must be placed in the
wax tank and the heat preservation tank. Under normal conditions, more than half of the wax pot is
appropriate, and dry burning is strictly prohibited.

When the paraffin is not completely melted, or the wax nozzle has not reached the set
temperature, the manual or foot switch cannot be used to prevent wax leakage from the wax nozzle

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and blockage of the pipeline.

The machine is equipped with a temperature overheat protector, when the heater temperature
exceeds the dangerous temperature of 100 ℃, the temperature protection will automatically cut off
the heating power. When lower than this temperature, heating will resume automatically.

In order to prolong the service life of the freezer compressor, the continuous working time
should not exceed 4 hours each time. After power off, it must be turned on for more than 5 minutes!

Before heating, please pay attention to the preset temperature value, which should be within
the melting point of the wax. (Normally between 60℃-65℃) It depends on the ambient temperature,
63℃-65℃ in winter and 60℃-63℃ in summer.

Water or other liquids are not allowed to flow into the chassis, and the wax tank should not
contain other debris.

During the heating process, do not open the cylinder head. (It takes about 40 minutes for the
wax temperature to reach 60℃-65℃.

When embedding, prevent impurities from entering the wax tank, so as not to block the wax
flow nozzle.

Non-professionals should not disassemble by themselves, otherwise the consequences will

be at their own risk.

9. Maintenance
Non-professionals should not disassemble by themselves. Under the condition that users abide by the
rules of use, the whole machine will be guaranteed for one year free of charge from the date of sale
(subject to the invoice). For products that exceed the warranty period, our company will provide
long-term maintenance services according to regulations. Otherwise, you will be responsible for the
consequences.
In order to make the embedding machine work properly for a long time, we still recommend:
Lay the machine flat in a fixed position, away from the fire source.
The machine should have good grounding and ventilation measures.
After each use of the machine, the residue on the surface of the machine should be removed to
ensure that the machine is clean.

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9.1 Troubleshooting
Fault Cause Method
No action at boot Power is not connected Connect the power and restart
Switch not turned on The freezing table needs to close the front
and rear switches, and the switch
indicator light is on
Fuse not connected Check the fuse for damage and replace
the fuse
Light is not on Fuse damaged Check for damaged fuses or contact
technical support
The lamp bead is broken Replace the lamp bead or contact
technical support
No heating Fuse damaged Replace the fuse or contact technical
support
No heating indicator light Heater damaged Contact Technical Support
is red
No heating indicator light Temperature sensor is Contact Technical Support
is orange broken
No wax Wax not melted Insufficient heating time, continue
heating
Solenoid valve blocked Contact Technical Support
No wax or leaking wax Solenoid valve is broken Contact Technical Support
The leaking wax solenoid There is a foreign body in Clean the filter, contact technical support
valve opens and the sound the solenoid valve
is normal
The light will flash after The power supply voltage is Check if the AC220V voltage is normal
turning on unstable
Turn on (green light) Control relay is broken Contact Technical Support
heating
The temperature sensor is Contact Technical Support
Excessive temperature
broken or the main control
fluctuations
board U2 fails to produce
The power plug is loose or Check the power plug or contact technical
No display on screen the ten 5V power supply support
fails
The driver board Q1 fails or Contact Technical Support
Wax bath not warming up
the associated wire is loose
Workbench does not heat The driver board Q3 fails or Contact Technical Support
up the related wires are loose
Temperature display is not Loose or failed temperature Contact Technical Support

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 stable sensor
The temperature does not Contact Technical Support
rise to the preset Temperature protector failed
temperature
A key is stuck or the mask Contact Technical Support
Key operation is invalid
presses the switch
The wires are not connected Check the wire connection
The tissue cooling center properly
does not cool Controller or compressor Contact Technical Support
damaged
Contact Technical Support
Compressor damaged
Temperature does not drop
Contact Technical Support
Lack of refrigerant

10. Inspection before power-on after unpacking

10.1 Open the upper cover to check whether all fastening screws are loose.
10.2 Check whether the circuit boards and connectors are loose or fall off.
10.3 Open the rear box panel to check whether the barrier-free fasteners are loose or fall off.
10.4 Check whether there is a three-core power supply in the power socket outside the box and it is
reliably grounded.
10.5 List of accessories
No. Name Qty. Remark
1 Foot switch 1
2 Power cord 1
3 Fuse tube 2 250V 5A
Fuse tube 4 250V 10A
4 User manual 1
5 Warranty card 1
6 Certification 1
7 Quality tracking card 1
8 Embedded frame 1
9 C13-C13 power cord 1
Please check whether the real thing in the package matches your order. If you have any questions,
please contact the seller immediately.

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 11. Warranty
Dear customer: any product may fail, please monitor the operating status of the equipment in real
time during use, If there is any abnormality, please refer to the manual to deal with it. If it still cannot
be solved, you should notify the service center of the company in time to avoid any loss to you.
1. From the date of sale of the equipment (subject to the invoice), the whole machine is guaranteed
for one year free of charge and enjoys lifetime service.
2. Warranty certificate: When you need normal consultation or maintenance, please contact our local
after-sales service center with the warranty certificate and purchase invoice and keep the warranty
certificate properly.

12. Storage and Transportation

●Storage: The machine should be stored in a clean room with relative humidity not exceeding 85%,
no corrosive gas and good ventilation.
●Transportation: "Handle with care", "Afraid of getting wet", "Upward".
1. The instrument must be checked for firmness and completeness of labels before shipment. It is
strictly forbidden to put it upside down or horizontally during transportation.
2. The instrument is only allowed to be transported upright.
3. When carrying the instrument, it is not allowed to grab the top of the wax nozzle.
4. The protective devices on the instrument and accessories are not allowed to be removed or
altered.

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JINAN BIOBASE MEDICAL CO.,LTD
NO.019 QISHAN ROAD, LAIWU HIGH TECH ZONE, JINAN,
SHANDONG,CHINA
Tel: +86-531-81307661
Inquiry: export@biobase.com
Complaints: customer_support@biobase.cc
After-sales service: service_sd@biobase.cc; service_ivd@biobase.cc
Web: www.biobase.cc/www.meihuatrade.com / www.biobase.com