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Optic: Generalities: Semester: 2 Academic Year: 2021-2023
Optic: Generalities: Semester: 2 Academic Year: 2021-2023
Lecturer
Pr. Malika ÇAOUI
Médecine Nucléaire
Semester : 2 Module
BIOPHYSICS
www.um6ss.ma
Overview of the course
• Geometric Dioptric
• Dioptric of the normal eye
• Spherical ametropias
• Non-spherical ametropias: Astigmatism
• Diagnosis of ametropias
• Visual acuity
• Study of refraction: subjective and objective methods
• Perception of the retinal image
• Color vision
2
General course objectives
• Distinguish the different transparent medium of the normal eye and their optical characteristics
• Differentiate between spherical and non-spherical ametropia
• Identify a spherical ametropia and an astigmatism
• Determine a power, the different parameters of accommodation and the degree of ametropia
• Approach the study of refraction by subjective methods
• Recognize the characteristics of a corrective lens
3
Review of basic notions in optics
Generalities on the sense organs
4
Diopter (US)/Dioptre (GB)
• Dioptre : optical surface of any form separating 2 media of different (¹) refractive indexes
Dioptrique Oculaire et Amétropies : Aspects biophysiques –
• It has - at least one center of curvature C and a radius of curvature (ex. R = CI) Pr. Michel Zanca –Montpellier
- at least one vertex S : which is the point where the surface intersects with the optical axis
- A spherical dioptre has the same radius of curvature along all meridians
- A non-spherical dioptre has ¹ radii of curvature along ¹ meridians : as many types of meridians ¹ as R ¹
• A dioptre is an interface that can be: Transparent that deflects light: refraction
Opaque which absorbs and/or reflects it
• A ray of light passing through C is not deflected because it is perpendicular (⊥) to the diopter (zero incidence)
• P and P' are Conjugate Points in the diopter :
• I being the point of incidence,
• the point (object) P is "transformed", via the diopter, into its conjugate (image) P'
5
Meridian
Refracted Ray
Incident ray
Normal to the dioptre: The axis perpendicular to the diopter, through the point of incidence
Dioptrique Oculaire et Amétropies : Aspects biophysiques – Pr. Michel Zanca –Montpellier 7
Physical Message Electromagnetic Ray
Generalities
Reception of external Enargy Ocular Glob
o The sensory functions create an interface between our
environment and the cerebral representation that we
Transduction: transformation of E into have of it.
Nerve Impulse (NI)
Retina
o The human being receives information on the external
world via the sense organs: Hearing - Vision - Touch -
Transmission NI via optic ways Optic ways
Smell - Taste
o Sense organs: receptors of energy that they receive in
Sup Nerve Centers : Interpretation Cortical areas different forms
o A sensory function is a chain of measurement that
consists of the reception, transformation and analysis of
Elaboration of sensorial a specialized form of energy
message: memorization Visual Sensation
Schematic representation of visual function AURENGO André - PETITCLERC Thierry - KAS Aurélie - Biophysique (4° Éd.)
8
The eye: Generalities
• The transmission of light from the outside to the retina: a step that obeys the laws of geometric optics: ocular dioptric
• The transduction of light into nerve impulses inside the retina, its propagation and the elaboration of a sensation by
the Superior Nervous Center : Perception of the retinal image
Geometric Optics
Lecturer
Pr. Malika ÇAOUI
Médecine Nucléaire
Semester : 2 Module
BIOPHYSICS
www.um6ss.ma
Plan
• Basic definitions
• Spherical dioptric : General relationship
Power of the diopter
Focal length of the diopter
Role of the sign of the power
• Cylindrical diopter - Toric diopter
• Association of several diopters : Spherical diopters
Cylindrical or toric diopters
• Converging spherical lenses
11
• Divergent spherical lenses
Geometric Optics : generalities
Index of refraction or the refractive index
• In a homogeneous environment, light always propagates in a straight line.
• In a transparent medium x ¹ of vacuum, light propagates at a speed vx < c : velocity (speed of light in vacuum)
• The index of refraction nx in this transparent medium x is by definition : c nair = 1
nx = ----
vx nwater= 1,336
Diopter
• Dioptre : surface that separates 2 transparent mediums with different refractive indexes : n1 and n2
• Refraction : Light propagates in a straight line in space, but when it meets a surface separating two transparent mediums
of index ¹ , its direction changes: this phenomenon of deviation is called : refraction.
• A stigmatic optical system gives a point image of a point object, which means that all the light rays coming from the same
point converge on the same point. 12
Spherical Diopter
• It is a spherical surface separating 2 homogeneous transparent mediums of n ¹ , separated by :
• a single center C and a single radius of curvature R , a vertex S,
• A single type of meridian, all identical because R unique
• It is a Transparent Interface which deflects the light (refraction)
• The principal axis is the SC ray passing through the vertex S. NI is the normal to the diopter at the point of incidence
• A spherical diopter is a stigmatic system.
13
Dioptrique Oculaire et Amétropies : Aspects biophysiques – Pr. Michel Zanca –Montpellier
Spherical Diopter n1 n2
Positive direction
P1
P2
1. General relation
• It is a spherical dioptre
S 0 Op#c Axis
14
Spherical Diopter
2. The power of the dioptre is : p
n2 – n1 The power π reflects the importance of the deviation of the
• Dimension : Length -1 . p = ----------
• Unit of p : m-1 = Diopter : D
r beam (so its convergence or divergence)
If r = ∞, π = 0 => plane dioptre : no vergence
S. O F2 F2 O S
i i
Sense Sense
Convergent meniscus
17
Divergent spherical lenses
Faisceau plan
• An object point situated at infinity ¥, the cylindrical diopter will produce 2 images in the form of straight lines: focal lengths
• Vertical focal point due to power p ¹ 0: // axis of cylinder ® PM : MH ( cylinder axis)
• Horizontal focus due to power p = 0 ⊥ cylinder axis and situated at ¥ PM : MV ( // cylinder axis) 20
Cylindrical lens with horizontal axis
Horizontal Focal
Vertical Focal
21
A toric Diopter
• A circular diopter in the horizontal plane is given a rotational motion of radius r' (r'¹ r)
around a horizontal axis xis SO
r
• The circle of radius r describes a portion of surface named toric characterized by 2 radii :
r’ • r and r’ ¹ ; so power p ¹ 0 (≈ buoy) p n –n
= p H = ----------
2 1 ® Vertical Focal : F
r V
p = p V = n----------
2 – n1 ® Horizontal Focal : F
S 0 r H
Horizontal Focal
Vertical Focal
Astigmatic cornea
Astigmatic cornea
The beam of red rays is refracted by the most arched meridian The beam of green rays is refracted by the horizontal meridian and
(vertical) and focused in a point in front of the retina. focused on a point behind the retina.
http://www.mguedj.com/Astigmatisme.html 27
Summary
• Refractive index of the considered medium: n = v/c; with v: speed of light in the medium, c the celerity of light (in vacuum)
• Diopter = index / distance
• Object point: the point from which the light leaves (comes from)
• Image point: where the light goes (where it comes)
• Real space, before the diopter for objects, after it for images (in the direction of light)
• Virtual space, after the diopter for objects, before it for images (in the direction of light)
• Conjugate points: object and image points in relation to a diopter
• Thin lenses :
• It is a system consisting of 2 diopters, not far from each other, with equal indices of the media:
• Ocular Dioptric and Ametropias : Biophysical aspects - Pr. Michel Zanca - Faculty of Montpellier
• Medial Biophysics : Volume 1 Fasciucle 2: Elements of Radiation Physics - Jacques Llory - Faculty of Montpellier
• Refraction and refractive anomalies - 2013- Collège des Ophtalmologistes Universitaires de France (COUF) - UMVF - Université Médicale Virtuelle
Francophone
• Polycopié National du Collège des Ophtalmologistes Universitaires de France 2009-2010 - Université Pierre et Marie Curie- France
• http://www.gatinel.com/recherche-formation/astigmatisme/
• https://www.cinenow.fr/tutoriels-guides/2107-un-peu-de-physiologie
31
Dioptric of the Normal Eye
Lecturer
Pr. Malika ÇAOUI
Médecine Nucléaire
Semester : 2 Module
BIOPHYSICS
www.um6ss.ma
Plan: Dioptric of the Normal Eye
https://www.perkins.org/the-visual-pathway-from-the-eye-to-the-brain/
35
Description of the eye globe
• Sphere of wall constituted by 3 concentric tunics:
• Ext fibrous tunic: sclera which in front takes a domed (convex) shape and becomes transparent: cornea
• Middle tunic, vascular: including the choroid, the ciliary body and the iris (color varies according to individuals).
• Internal tunic, nervous: retina
• Lens, deformable structure for a focus, is connected to the ciliary muscle by fibers: the zonule. It divides the contents of the
eye into 2 chambers:
• Anterior: in front containing the aqueous humor (composition close to the physiological serum)
• Posterior: back containing the vitreous humor (gel rich in proteins)
• The transparent mediums of the eye through which the light passes to reach the retina are: the cornea, the aqueous
humor, the lens and the vitreous humor
• The iris, of variable color (not transparent) is located between the anterior chamber and the lens
• It is pierced by a central orifice: Pupil which has the role of a diaphragm
• Pupil: diameter varies, from 2 (myosis) to 8 mm (mydriasis), by reflex reaction to the light or during accommodation
36
Retina
• Transducer and 1st step of the visual message processing. Extension of the brain. Very complex organization
• Circular symmetry of visual axis shifted / optic axis: joins the top of the corneal dioptre to the center of the retina: Fovea.
• Papilla: zone of emergence of the vessels and departure of the optic nerve: devoid of receptor cells: Blind spot
• Macula: central area of the retina covers 15 - 20° of the visual field: max thickness: 500 𝝁m composed exclusively of cones+++.
• In macula center, the fovea forms a small depression covering 5° of the visual field: where visual acuity is the highest: Foveola
• The photoreceptors of the retina: cones more concentrated in the macula / rods : in the periphery
Rods Cones
Topography Péripheral retina Supecially Fovea
Vision domain Nocturnal scotopic Diurnal photopic
Visuual Acuity Low High
Variance Single vision uncolored variant Trivariant colored Vision
Adaptation Important and slow Fast and low
Pigment Rhodopsine 3 different pigments
AURENGO André - PETITCLERC Thierry - KAS Aurélie - Biophysique (4° Éd.) 37
Transparent mediums of the eye
• Before arriving on the retina, the light crosses, in the eye, several transparent mediums of different indices
responsible for the convergence which ensures a luminous image on the retina.
• These different media normally constitute spherical diopters.
The cornea : Upper and transparent part of the sclera of n = 1,377 (/nair = 1)
o r ext = 7,8 mm nair = 1 1,377 1,337
o r int = 6,5 mm
7.8 mm; 6.5 mm 1,377 – 1
o The anterior corneal dioptre is of power p = ----------------- = + 48 D
7,8 . 10-3
Aqueous humor (HA): n = 1,337 : (close to water) is distributed in 2 spaces by the iris: extension of the choroid..
ü The iris (not transparent) is pierced by the orifice: pupil diameter varies from 2 to 8 mm by reflex
ü Posterior corneal dioptre is of power 1,337 – 1,377
p = ---------------------- = - 6 D AH
+ 6,5 . 10-3
38
Transparent mediums of the eye
Lens :
• Biconvex lens, of complex constitution (onion bulb): n varies from the center to the periphery Þ n average = 1.42
• Radii of curvature of the 2 faces change during accommodation. Normal eye at rest: : rant = 10 mm /rpost = 6 mm
• Anterior lens dioptre : 1,42 – 1,337
p = ------------------- = + 8 D
10 . 10-3
PR : ¥ R
S
Fovea
direction +: Medical The medical direction of the light is the opposite of the physical direction 40
Reduced Eye
• All the spherical diopters of the eye can be » assimilated to a single spherical diopter: Reduced Eye
• The reduced eye is then a spherical diopter of p = 60 D separating air (nair = 1) from water (neau = 1.337), we define :
1,337 – 1,000
o The power : p = --------------------- = + 60 D Þ radius Þ r = 5,6 mm
r
1,337
o The focal length image of this diopter is: f2 = ----------- = 22 mm
60
o The radius r varies with accommodation between a πmin (rest) of +60 D for distance vision (Pr), and a πmax for near
vision (Pp), which decreases with age (presbyopia).
n1 = 1,00 S n2 = 1,337
Reduced Eye
r = 5,6 mm Retina
If2I = 22 mm
• The powers p (being the sign according to the convention of physicists) : Positives for convergent diopters
Negatives divergent diopters
42
The accommodation
Necessity of accommodation
• The reduced eye has a power of 60 D and a length l = of 22 mm
• The image of an object located at infinity (beyond 5 meters) is formed on the retina and will be clear
• If this eye observes a close object situated at 20 cm (p1 = + 0,20 m), the image will be blurred at a distance p2
1
situated behind the retina (virtual image): ------ 1,337
+ -------- = 60 D Þ p2 = -24 mm (2 mm behind the retina)
0,2 p2
• The eye must then modify its characteristics to see clearly the close objects
R p2
p1 S
20 cm
Direction + : in medicine 22 cm 43
The accommodation
Mechanism of accommodation :
• It is a k of the power of the eye by k of the power of the lens whose radius of curvature (especially anterior) m :
• It is a very fast reflex phenomenon ( important in children 15 D) : " focus " in a fraction of a second
Characteristic of accommodation :
• AAccommodation Amplitude (AA in Diopter) is the k max of the p of the eye during accommodation AA = pmax - p min
• p2 : Distance Dioptre - Retina (the image in case of accommodation or not, is formed on the retina)
Pr 1 1
PR PP P2 R pmax - p min = AA = ----- - ------
S Pp Pr
Pr PA Pp Pp
pmin AA pmax 44
Characteristics of Accommodation: PR – PP – AA - PA
The Punctum Remotum : PR The Punctum Proximum : PP
• Conjugate point of retina when eye is at rest (does not • Conjugate point of the retina when eye accomodates to the max
accommodate)
• Pp is the distance from PP to t eye. P2 : Distance Dioptre - Retina
• Pr: Distance from PR to the eye. For a normal eye: Pr → +¥
• The power in accommodation is maximum :
• The power of the eye at rest is minimal : 1 n2
----- + ------ = pmax (accommodation max)
1 n2 Pp P2
----- + ------ = pmin (at rest )
Pr P2
Correction of presbyopia:
• The eye has insufficient power to see close-up objects: close-up vision (reading) is difficult, if not impossible.
• The power of the eye is increased by converging spherical lenses that the subject uses only for near vision
47
AA
Presbyopia
14
Variation of AA with age and situation of PP
12
Age AA S-PP Age AA S-PP
10 (Ans) (D) (cm) (Ans) (D) (cm)
10 14 7 40 4,5 22
8
15 12 45 3,3 30
6 20 10 50 2,5
25 8,5 55 1,7
4
30 7 14 60 1 100
2 35 5,5 65 0,50
70 0,25 400
0
10 20 30 40 50 60 70 Age en années
50