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Report of analysis

Acute Toxicity of mixed substances

Name and/or code of the product: BX10 AQUEOUS RESIN


Manufacturer: Lapha Them Co., Ltd.
Nature/industrial category: Paint additive.
Intended use: Paint additive for the manufacture of waterborne plastic paints for the control and repellence of
flying and crawling insects.

1. Chemical composition of active ingredients:

1. Alpha-Cypermethrin
CAS No.: 67375-30-8
EC No.: 614-054-3

2. D-Allethrin
CAS No.: 231937-89-6
EC No.: -

3. Pyriproxyfen
CAS No.: 95737-68-1
EC No.: 429-800-1

2. H and P Statements:

Hazard statement(s):
H302: Harmful if swallowed.
H332: Harmful if inhaled.
H400: Very toxic to aquatic life.
H410: Very toxic to aquatic life with long lasting effects.

Precautionary statement(s):
P102: Keep out of reach of children.
P260: Do not breathe dust/fume/gas/mist/vapours/spray
P273: Avoid release to the environment.
P280: Wear protective gloves/face protection.
P301+P312: IF SWALLOWED: Call a POISON CENTER/doctor/if you feel unwell.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for
breathing.
P501: Dispose of contents/container to in accordance with local/regional/national/international
regulation.

3. Label elements

Regulation (EC) No 1272/2008 (CLP):

GHS Pictograms:

Signal word:
WARNING

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Report of analysis
Acute Toxicity of mixed substances

4. Concentration of active ingredients with Acute Toxicity

Number Chemical Name Formulation Acute Toxicity


percentage C (%w/w)
Oral Dermal Inhalation
1 Alpha-Cypermethrin 5.82% Acute Tox. 3, H301 - -
2 D-Allethrin 11.16% Acute Tox. 4, H302 - Acute Tox. 4, H332
3 Pyriproxyfen 0.53% <1% <1% <1%

5. Calculation of Acute Toxicity of the mixture is given by:

𝟏𝟎𝟎 𝑪𝒊
=�
𝑨𝑻𝒎 𝑨𝑻𝒊
𝒊

where:

- 𝑪𝒊 represents the concentration of the active ingredient.


- 𝑨𝑻𝒊 represents the Acute Toxicity of the active ingredient.
- 𝑨𝑻𝒎 represents the Acute Toxicity of the mixture.

a) Calculation of Oral LD 50 (rat) of the mixture:


*Relevant ingredients:

- Alpha-Cypermethrin: LD 50 (Oral) = 123 mg/kg.


- D-Alletrhin: LD 50 (Oral) = 900 mg/kg

100 5.82 11.16


= + => 𝑂𝑟𝑎𝑙 𝐿𝐷50 = 𝟏, 𝟔𝟕𝟓 𝒎𝒈/𝒌𝒈
𝑂𝑟𝑎𝑙 𝐿𝐷50 123 900

b) Calculation of Dermal LD 50 (rat) of the mixture:

No relevant ingredients. Ingredients are not classified in Acute Toxicity (Dermal) or are less than 1% in
concentration.

c) Calculation of Inhalation LC 50 (rat) of the mixture:


* Relevant ingredients:

- D-Allethrin: LC 50 (Inhalation) = 3.88 mg/l

100 11.16
= =>∗ 𝐿𝐶50 34.77 mg/l
∗ 𝐿𝐶50 3.88

As it is vapor, this value should be divided by a factor of 2. So the result is:

34.77
𝐿𝐶50 = = 𝟏𝟕. 𝟑𝟖 𝒎𝒈/𝒍
2

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Report of analysis
Acute Toxicity of mixed substances

6. The result of the composition gives Acute Toxicity (rat) values of the final product:

Product Name Acute Toxicity


Oral LD 50 (rat) Dermal LD 50 (rat) LC 50 (rat)
BX10 AQUEOUS RESIN 1,675 mg/kg - 17.38 mg/l

7. Standard Toxicity Categorization from GHS:

The four toxicity categories, from one to four are:

• Toxicity category I: Highly toxic and Severely irritating.


• Toxicity category II: Moderately toxic and Moderately irritating.
• Toxicity category III: Slightly toxic and Slightly irritating.
• Toxicity category IV: Practically non-toxic and not an irritant.

Type Category I Category II Category III Category IV


Oral LD 50 (rat)
≤ 50 mg/kg > 50 to 500 mg/kg > 500 to 5,000 mg/kg > 500 mg/kg
Dermal LD 50 (rat)
≤ 50 mg/kg > 50 to 500 mg/kg > 2,000 to 20,000 mg/kg > 500 mg/kg
Inhalation LC 50 (rat) (vapor)
≤ 0.2 mg/l > 0.2 to 2 mg/l > 2 to 10 mg/l > 10 mg/l

8. Conclusion:

Following the above standards the subjected product BX10 AQUEOUS RESIN should be categorized as
Category IV.

End of the report.

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