Modeling, Mathematical Methods and

Computer Simulation of Tumour Growth

and Therapy
Sprawozdania

Informacje na temat projektu

M3CS-TU TH Finansowanie w ramach

FP6-MOBILITY
Identyfikator umowy o grant: 503661
Całkowity budżet
Data rozpoczęcia Data zakończenia € 2 942 447
1 Czerwca 2004 31 Maja 2008
Wkład UE
€ 2 942 447

Koordynowany przez
POLITECNICO DI TORINO
Italy

Final Activity Report Summary - M3CS-TU TH (Modeling,

mathematical methods and computer simulation of tumour
growth and therapy)
The activities of the research training network was organised from the very beginning into six tasks, each
one focusing on the specific aspects of the research and related training:

- Mathematical modelling and computer simulation at the cellular and sub-cellular scales.
- Mathematical modelling and computer simulation at the macroscopic scale.
- Mathematical modelling and computer simulation for cancer therapy.
- Qualitative analysis and multiscale methods.
- Experimental aspects and validation.
- High-performance algorithms for tumour simulations.

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The activities related to the tasks produced more than 300 publications in refereed journals, one over five
deriving from the activity of the young researchers employed by the Research Training Network and one
over six from joint collaborations.

Ten thematic volumes were published related to microscopic modelling, macroscopic modelling and
computational aspect, with the discussion of some therapeutical actions, multiscale modelling and
qualitative aspects. In addition, five special issues of well known scientific journal were organised and
devoted in particular to the research activity of the young researchers. Many articles received honours and
awards by ranking agencies and the software PhasTrans received a positive decision for development
and commercialisation of a high-technology incubator.

Apart from the above list of numbers, the activities of the network had the merit to bring a topic to the
attention of the researchers, especially the young researchers through the organisation of summer schools
and thematic workshops. These periodic appointments acted as a catalyser stimulating the entire scientific
community. In fact, if one compares the number of papers published on scientific journals on cancer
modelling before and after the establishment of the research training networks, it is possible to realise that
they more than triplicate. This result was not achieved by the participant in the network alone but was
induced by their activities.

Coherently with what just stated, looking at the number of presentations on cancer modelling and related
issues in the main conferences held in Europe and worldwide it can be seen that the number of talks
dramatically increased (more than four times with respect to ten years ago). More than two thirds of them
are held by European scientists and both the amount and the rate of increase of presentations are bigger
in European conferences. In fact, it is recognised worldwide that through the activity of the networks
Europe achieved a leading role on the subject and actually other countries would like to import this type of
experience and organisations.

The other merit of the research training network was to break the barrier with other neighbouring research
fields, building a multidisciplinary community. The relations and collaborations with the biomedical world
are now strong and consolidated.

From the scientific viewpoint one of the biggest advances in research is the acquired ability to link
mathematical modelling and scientific computing with real bio-medical data.
Some of the mathematical framework developed are now able to insert measurements obtained at the
sub-cellular and cellular scale not only in mathematical models working at the pertinent scale, but also to
upscale some of them in order to be used by models working at the tissue level. Finally, a bridge between
mathematical models dealing with phenomena occurring at the cellular scale and those dealing with
macroscopic behaviours was obtained.

Ostatnia aktualizacja: 23 Listopada 2011

Numer rekordu: 49484

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Permalink: https://cordis.europa.eu/project/id/503661/reporting/pl

© European Union, 2022

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