Course File: Form 02

KAMPALA
INTERNATION
AL
UNIVERSITY FACULTY OF CLINICAL MEDICINE AND DENTISTRY
KAMPALA INTERNATIONAL UNIVERSITY
FACULTY OF CLINICAL MEDICINE AND DENTISTRY
DEPARTMENT OF PATHOLOGY
COURSE TITLE: HAEMATOLOGY AND BLOOD TRANSFUSION

BMS-204/BCM PATHOLOGY JANUARY 2024- MAY 2024

LECTURERS NAMES: - DR. AKABA KINGSLEY - Tel: +256 744959140/ +234 8134205756
- DR. SURAT AKIB - Tel: +256 752574699
- MR. BENJAMIN NUWAREEBA Tel: +256 759814745/0773562236
SHIFT – DAY
Year [2023/2024]
COURSE OBJECTIVES:
By the end of this course the student should be able to:
1. Describe the formation and maturation sequence of each cell of the haemopoietic system including their regulatory mechanisms and
know the normal ranges for blood cell counts.
2. Describe the roles of iron, vitamin B12 and folic acid in red cell development.
3. Discuss the structural and functional properties of the haemoglobin molecule, the genetics, clinical features and management of the
common haemoglobinopathies.
4. Define anaemia in different ways.
5. Discuss the classification of the anaemias and the deficiencies of the haematinics in detail
6. Evaluate and outline the management of other red cell abnormalities.
7. Discuss the lymphoreticular system in terms of the structure and function of the spleen and its disorders.
8. Describe normal and abnormal haemostasis and be able to do the laboratory evaluation.
9. Discuss the neoplastic haematological disorders and outline the principles of their management.
10. Describe major blood groups, blood group serology and the principles behind transfusion of blood and its products.
11. Perform simple laboratory investigations in haematology and blood transfusion.
 Course File: Form 02
KAMPALA
INTERNATION
AL
UNIVERSITY FACULTY OF CLINICAL MEDICINE AND DENTISTRY

MODE OF DELIVERY
E. Learning / Tutorials/ Practicals/ Role-plays and simulation sessions/Student presentations/Directed and independent self-study/
Essay writing

STUDENTS ASSESSMENT
1. Continuous assessment tests comprising of MCQs, short essays, Random assessment tests, tutorials, practicals (40%)
2. End of course examination- MCQ, short essays (50%)
3. Viva Voce (10%)

WEEK OF DATE TOPICS LECTURER MAIN ADDITIONAL

SEMESTER REFERENCE LITERATURE
Week 1 08-12/01/ 2024 A. NORMAL HAEMATOLOGY Dr. Kingsley/ Hoffbrand's Clinical
1. Introduction to Haematology Dr. Akib/Mr. Essential Hematology Atlas
2. Haemopoiesis Nuwareeba Haematology Bernadette F.
3. Haemoglobin-Structure & Function A. Victor Rodak, Jacqueline
4. Normal blood ranges/Red cell Indices Hoffbrand , H. Carr
David P. 6th Edition
Steensma
8th Edition Dacie and Lewis
Practical
Week 2 15-19/01/ 2024 5. Anticoagulants/ stains used in the laboratory/ Haematology
Transport of Blood Specimens/Processing Barbara Jane Bain ,
Times for Blood Imelda Bates ,
6. Normal Haemostasis Mike A. Laffan
7. Tests of Haemostatic Function 12th Edition

Oxford Handbook
of Clinical
 Course File: Form 02
KAMPALA
INTERNATION
AL
UNIVERSITY FACULTY OF CLINICAL MEDICINE AND DENTISTRY
Week 3 22-26/01/ 2024 B. HAEMATOLOGICAL DISORDERS Haematology
1. Definition and Classification of Anaemia Drew Provan,
2. Compensatory mechanisms in Anaemia Trevor Baglin
3. Abnormal red cell shapes/ Red cell inclusions Inderjeet Dokal ,
Johannes de Vos
4th Revised edition
Week 4 29/01-02/02/2024 4. Disorders of iron
- Iron Metabolism Lecture Notes:
- Iron deficiency Anaemia Haematology
Chris S. R. Hatton ,
-Iron Overload Nevin C. Hughes-
-Haemochromatosis Jones , Deborah
- Haemosiderosis Hay , David
Keeling
Week 5 05-09/02/2024 5. Megaloblastic Anaemias 9th Revised edition
-Vitamin B12 deficiency
- Folic acid deficiency Hutchison's
Clinical Methods:
6. Haemolytic Anaemias An Integrated
-Thalassemias Approach to
- G6PD deficiency Clinical Practice
- Pyruvate kinase deficiency Michael Glynn
- PNH MA MD FRCP
FHEA, (M Drake
Week 6 12-16/02/2024 - Sickle Cell Diseases DM }
-Thalassemias 24th edition

Week 7 19-23/02/2024 7. Anaemia of Bone Marrow Failure Davidson's

8. Disorders of the spleen Principles and
-Asplenia Practice of
- Hypersplenism Medicine: Mark
-Tropical Splenomegaly Syndrome W.J. Strachan,
Nicki R Colledge,
Stuart H. Ralston
Ian Penman
24th Edition
 Course File: Form 02
KAMPALA
INTERNATION
AL
UNIVERSITY FACULTY OF CLINICAL MEDICINE AND DENTISTRY
Week 8 26/02- 01/03/ 2024 CAT WEEK

Week 9 04- 08/03/ 2024

C. HAEMOSTATIC DISORDERS
1. Disorders of Haemostasis
- Platelet Disorders
- ITP, TTP, HUS
-Vascular Disorders
- Coagulation Disorders
- Congenital
- Haemophilia
- Von Willebrand
- Acquired
- Anticoagulant overdose
- DIC,
- Vitamin K deficiency
- Liver Disease

2. Thrombosis and Anticoagulation

Week 10 11- 15/03/ 2024 D. NEOPLASTIC DISORDERS

1. Leukaemias
- Acute Leukaemias
- Chronic Leukaemia
2. Myeloproliferative Disorders
- Polycythaemia
- Essential Thrombocythaemia
- Myelofibrosis

Week 11 18- 22/03/ 2024 3. Lymphomas

-Hodgkins Lymphoma
-Non Hodgkins Lymphoma
- Burkitts Lymphoma
 Course File: Form 02
KAMPALA
INTERNATION
AL
UNIVERSITY FACULTY OF CLINICAL MEDICINE AND DENTISTRY
Week 12 25- 29/03/ 2024 E. BLOOD TRANSFUSION
1. Red Blood Cell Antigens
2. Blood Donation
3. Blood Component Therapy

Week 13 01/04- 05/04/ 2024 4. Blood Preservation/ Pre-

Transfusion Tests
5. Red Blood Cell Antibodies
6. Haemolytic Disease of the
Newborn
7. Complications of Blood
Transfusion

Week 14 08/04- 12/04/ 2024 TUTORIALS 1 to 8

Week 15 15/04- 19/04/ 2024 TUTORIALS 9 to 16

Week 16 22/04- 26/04/ 2024 MOP UP SESSION

Week 17 29/04- 03/05/ 2024 REVISION WEEK

Week 18 06/05- 10/05/ 2024 PATHOLOGY EXAMS

Week 19 13/05- 17/05/ 2024 PATHOLOGY EXAMS

 Course File: Form 02
KAMPALA
INTERNATION
AL
UNIVERSITY FACULTY OF CLINICAL MEDICINE AND DENTISTRY