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And also alleviated the depletion of GSH, GPX, SOD, CAT, NO, MPO and LPO levels in rats. We,
therefore, evaluated the protective effect of aqueous and propanoic extract of “oruwo” leaves (
Morinda lucida ) on acetaminopheninduced oxidative damage and hepatic injury in rats. However,
Bean-seeds were more sensitive to saponin effects especially the roots compared with Maize seeds (
Tables 3-5 ). These rats were gotten from Ayoola farmhouse in Ilorin, Kwara state, Nigeria. The
measurements in the test cultures were compared with those of controls to get an index of inhibition
of seed germination and seedling growth. The extract was then filtered with a Whatman filter paper
and subjected to rotary evaporation. He loves writing helpful articles on health and fitness, which he
enjoys sharing with everyone. One of the health effects of herbal medicines is the hepatotoxic
effects. Phytochemical, proximate analysis, vitamin and mineral composition of aqueous extract of
Ficus capensis leaves in south eastern Nigeria. The plants were taken to the Department of plant
biology, Ondo State University of Science and Technology, Okitipupa for identification. Thereafter,
the rats were sacrificed under mild anesthesia, blood samples were collected to estimate serum
Alkaline phosphatase (ALP), Aspartate aminotransferase (AST), Alanine aminotransferase (ALT),
Total bilirubin and Total cholesterol levels. At high doses, acetaminophen induces toxicity to the liver,
which is usually characterized by chest pain, vomiting, diarrhea, and sometimes shock. All the data
of treatment groups were compared with the control group by using a one-way ANOVA followed by
Dunnett ’ s multiple comparison tests. Overall, these ameliorative potentials of extracts of Morinda
lucida confirms the hepatoprotective effect of the plant. Other ailments the herb treat and manage
include diabetes, stomach ache, ulcers, dysentery, hypertension, gonorrhea and ulcers. Animal livers
were also removed, homogenized and examined for oxidative stress and antioxidant parameters.
Therefore, further studies may be necessary to investigate and confirm the exact mechanisms of
hepatoprotection. The formation of persistent foam was evidence of the presence of saponins. For
red colours, the fibres to be dyed must first be mordanted with tannin-containing plants and alum. A
superb, if terse, resource, it is also available electronically on the Web - see. Oruwo leaves are
considered a potent pain killer because of their ability to relieve pain. The Board of Trustees of the
Royal Botanic Gardens, Kew. The result is similar in structure to the fruit of Myrianthus arboreus.
Always consult your physician first before taking this plant as a herbal medicine. The action you just
performed triggered the security solution. There are several actions that could trigger this block
including submitting a certain word or phrase, a SQL command or malformed data. It aims to
publish the highest quality material, both clinical and scientific, on all aspects of medicine.
Concentrated H2SO4 acid (2 mL) was then poured down the side of the tube so as to form a layer
below the acetic acid. About 10 ml of distilled water was added to each culture every day from the
second day of culturing so as to replace water loss during evaporation.
The extract was then filtered with a Whatman filter paper and subjected to rotary evaporation.
Animal livers were also removed, homogenized and examined for oxidative stress and antioxidant
parameters. The mixture was filtered while hot and allowed to cool. 5 mL of filtrate was diluted to
10 mL with distilled water and shaken vigorously for 2 min. There are several actions that could
trigger this block including submitting a certain word or phrase, a SQL command or malformed
data. Many studies still need to conducted on the plant. Two anthraquinols, oruwal and oruwalol,
have also been found; these give a yellow colour and possibly are intermediates in the formation of
anthraquinones. This is an open-access article distributed under the terms of the Creative Commons
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium,
provided the original author and source are credited. Thus, high-risk patients such as the elderly,
children, those taking several medications for chronic conditions, or congestive heart failure, should
be more cautious in taking this plant. However, co-treatment with extracts from Morinda lucida
alleviated this effect and caused a reduction in levels of AST, ALT ALP, and total bilirubin, when
compared with the APAP-treated group. However, bean-seeds were more sensitive to saponin
effects especially the roots compared with Maize Seeds. Filtrate (1 mL) was mixed with two drops
of Wagner’s reagent, then two drops of Dragendorff’s reagent were added to another 1 mL of the
filtrate, and the mixtures were then observed for turbidity. All the data of treatment groups were
compared with the control group by using a one-way ANOVA followed by Dunnett ’ s multiple
comparison tests. The root bark and leaves are also used to treat different types of fever, including
yellow fever and trypanosomiasis. Overall, these ameliorative potentials of extracts of Morinda
lucida confirms the hepatoprotective effect of the plant. It aims to publish the highest quality
material, both clinical and scientific, on all aspects of medicine. Tests with animals confirm the
attributed activity of several traditional medicinal applications of Morinda lucida. Comments have to
be approved before they are shown here. Data were analyzed by using Microsoft Excel 2007
(Redmond, Washington, USA) and Graph Pad Prism 5 software. Our results thus show that extracts
(propanoic and aqueous) of leaves of Morinda lucida possess saponin and as such might have a mild
effect on blood glucose levels and possibly exhibit antimicrobial activities. More so, their application
in agriculture could effectively be exploited in weed-control, plant selection, and herbicidal
application, in seed preservation and in related micro field experiments. Total bilirubin and total
cholesterol were assessed following the manufacturer’s instructions using diagnostic kits obtained
from Diamond Diagnostic Cairo, Egypt. Acetaminophen is metabolized by cytochrome P450
enzymes of the liver and detoxified by glucuronidation as well as sulfation. Oruwo leaves are
considered a potent pain killer because of their ability to relieve pain. Always consult your physician
first before taking this plant as a herbal medicine. Importantly, the animals acclimatized to the
environment for 2 weeks before the initiation of the experiment. Phytochemical, proximate analysis,
vitamin and mineral composition of aqueous extract of Ficus capensis leaves in south eastern
Nigeria. There are also two species of liana in this genus which occur in the area. Other ailments the
herb treat and manage include diabetes, stomach ache, ulcers, dysentery, hypertension, gonorrhea
and ulcers. One of the health effects of herbal medicines is the hepatotoxic effects. Unlike most
members of Rubiaceae the stipules fall very early, leaving a clear scar.
Total bilirubin and total cholesterol were assessed following the manufacturer’s instructions using
diagnostic kits obtained from Diamond Diagnostic Cairo, Egypt. Oruwo leaves are considered a
potent pain killer because of their ability to relieve pain. The experiments were done in duplicates
and at room temperature, the culture was observed for 7 days, the roots- and shoot- lengths were
measured. This study has therefore revealed that the shoots, in general, were less sensitive than the
roots to Saponin-effects. Importantly, the animals acclimatized to the environment for 2 weeks before
the initiation of the experiment. In all the groups, differences were considered statistically significant
among groups when p. All the data of treatment groups were compared with the control group by
using a one-way ANOVA followed by Dunnett ’ s multiple comparison tests. Thirty-six rats were
randomly divided into six equal groups as outlined in Table 1. Many studies still need to conducted
on the plant. Please include what you were doing when this page came up and the Cloudflare Ray ID
found at the bottom of this page. Two anthraquinols, oruwal and oruwalol, have also been found;
these give a yellow colour and possibly are intermediates in the formation of anthraquinones. It lists
a number of the plant uses as well as the habitats and botanical descriptions of the plants. It is only
very rarely found in undisturbed forest. Analysis of the national multicenter study (1976 to 1985).
Botanical Journal of the Linnean Society 154: 455-495. Animal livers were also removed,
homogenized and examined for oxidative stress and antioxidant parameters. The roots have bitter
taste, and are used as flavoring for food and alcoholic beverages. Less than 5 volumes 30 days 8 - 9
volumes 40 days 10 and more volumes 45 days. Therefore, further studies may be necessary to
investigate and confirm the exact mechanisms of hepatoprotection. The extract was filtered and
diluted with an equal volume of distilled water and two drops of lead acetate solution were added,
shaken and filtered after standing for a few minutes. About 10 ml of distilled water was added to
each culture every day from the second day of culturing so as to replace water loss during
evaporation. These rats were gotten from Ayoola farmhouse in Ilorin, Kwara state, Nigeria. There are
several actions that could trigger this block including submitting a certain word or phrase, a SQL
command or malformed data. Filtrate (1 mL) was mixed with two drops of Wagner’s reagent, then
two drops of Dragendorff’s reagent were added to another 1 mL of the filtrate, and the mixtures
were then observed for turbidity. The formation of persistent foam was evidence of the presence of
saponins. He loves writing helpful articles on health and fitness, which he enjoys sharing with
everyone. It is known as Brimstone tree in the English language, Oruwo in Yoruba Language, and
Eze-ogu in the Igbo language, while its botanical name is Morinda Lucida. The mixture was shaken
and the presence of a pink, red or violet color in the ammonia phase indicated the presence of free
anthraquinones. On occasions of national grief or the death of a chief, the Ashanti people of Ghana
dye cotton cloths red with the root bark. However, co-treatment with extracts from Morinda lucida
alleviated this effect and caused a reduction in levels of AST, ALT ALP, and total bilirubin, when
compared with the APAP-treated group.