Professional Documents
Culture Documents
Communicable
Diseases Bulletin
www.haad.ae
Foreword
As part of HAAD mission to ensure reliable excellence in health care for the
community, prevention is the best approach to healthy community. Vaccination is
one of the most effective strategies to eliminate and control infectious diseases.
The introduction of exuded program of immunization in UAE, helped to eradicate
polio and today UAE is certified as polio free country. In addition, vaccines helped
to decrease the presence of several childhood illnesses such as measles
and rubella, which is clearly seen in our notified list of illnesses with very minimal
numbers reported for these diseases.
I Foreword 2
II Table of contents 3
X Activities 13-14
Cases Total
AFP * 1 3 2 4 2 6
Brucellosis 1 3 5 6 3 8 1 7 6 6 3 3 3 1 1 1 23 35 58
Chickenpox 80 110 520 550 886 931 162 276 244 541 49 215 4 51 4 9 3 1949 2686 4635
Cholera 1 1 0 1
Haemophilus influenzae 0 0 0
Hepatitis A 4 2 7 11 2 7 3 11 2 2 16 35 51
Influenza 1 2 3 4 1 1 2 2 5 1 5 1 2 1 14 17 31
Measles 1 1 0 2 2
Meningitis bacterial 2 1 1 1 1 2 1 1 1 5 6 11
Meningitis viral 1 1 2 2 2 1 1 2 2 6 8 14
Mumps 8 14 7 15 1 4 11 1 4 1 3 18 51 69
Pertussis 10 12 2 3 13 14 27
Rubella 1 4 1 1 5 6
Shigellosis 3 2 1 1 1 1 2 7 9
Tetanus 0 0 0
Tuberculosis (Pulmonary) 1 6 14 10 29 1 15 1 8 1 4 3 22 71 93
Tuberculosis 1 2 2 6 10 16 2 7 7 2 17 38 55
(Extra-Pulmonary)
Typhoid /Paratyphoid 1 1 1 1 4 5 21 5 54 4 16 3 8 1 4 20 109 129
Fever
Other Diseases 7 8 43 61 17 25 16 27 38 48 18 31 5 14 4 9 0 2 148 225 373
Total 132 177 648 724 978 1039 240 595 407 1139 125 537 30 249 24 103 12 16 2596 4579 7175
* The highlighted cells (with red numbers) indicate the age/gender categories that had the largest numbers of reported cases for the given illness.
The grand total after including all ruled out notifications will be 7522
that the vaccinated cohort is now at the age goes with Rotavirus seasonality.
Total 374
group 1-4 years, which used to be among the However, acquisition of rotavirus
most reported cases in previous years. is not always foodborne, and this
should be considered when inter-
Chickenpox preting the apparent trend.
2500
2010
160
2000
2012
140 2010
80
1000
60
40
500
20
0
0 Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec MONTH
MONTH
The number of reported cases started to decrease
Close to half the cases reported travel history, in May, as reporters were informed to refer to the
and only five had epidemiologic link to another case definition for reporting (which requires posi-
case. As appear in table 2 (page 5), close to tive culture or epidemiologic link in addition to the
half aged less than 14 y, and more than two clinical picture).
thirds were males.
Typhoid/Paratyphoid
Hepatitis A
2010
80
50 2010
2011
70
Number of notified cases
45 2011 2012
60
40 2012
Number of notified cases
50
35
40
30
30
25
20
20
10
15
0
10 Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
5 MONTH
0
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec All reported malaria cases are imported, and the
MONTH majority of them diagnosed after returning from
their holidays in malaria endemic countries.
Influenza
Malaria
60
500
Number of notified cases
2010
50 2010 450
2011
Number of notified cases
2011 400
40 2012
2012 350
30 300
250
20 200
150
10
100
0 50
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
0
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
MONTH
MONTH
Note: HAAD surveillance officers investigate individual cases, assess for outbreaks, and take action whenever indicated.
Visa screening is mandatory for all expatriates applying for work and/or residence in Abu
Dhabi Emirate. It consists mainly of screening for Human Immunodeficiency Virus (HIV), pul-
monary tuberculosis, and leprosy. Screening for Hepatitis B and syphilis are limited to a few
occupational categories. HAAD Visa Screening Standard is available at: http://www.haad.
ae/HAAD/LinkClick.aspx?fileticket=DDCVCmde9R0%3d&tabid=819
Around quarter a million people or more apply for visa medical screening every three months
in Abu Dhabi Emirate. During the second quarter of 2012, a total of 279,720 applicants were
screened in all HAAD-licensed Screening Centers (a total of nine centers in the three regions
of Abu Dhabi).
279720
250000
217114
200000
No. of Applicants
153704
150000
126016
100000
62606
50000
The table below shows the number and prevalence of positive cases among new and renew-
al visa applicants during the second quarter of 2012.
* Prevalence: the number of positive cases per 100,000 visa screened applicant
** This refers to active TB cases only
*** Applies to tested occupational categories
Given the large burden of some infectious diseases among certain high risk groups of adults (like
old people, people with debilitating medical conditions, travelers, and people in close contact
with or have frequent exposure to infections), the Health Authority of Abu Dhabi identified vac-
cines to be given to those high risk groups of adults as per best international practices and
WHO recommendations. The aim is to reduce preventable infections and related morbidity and
mortality and to enhance human’s health.
Based on the developed regulations:
• immunocompromising conditions
Adults with certain health conditions • Diabetes
• Chronic cardiovascular disease(except
Adults with certain non healthy practices hypertension)
• Chronic lung disease(including Asthma)
Travelers to high risk areas • Chronic alcoholism
• Asplenia
Contacts of cases with certain infections • Chronic liver disease
• Kidney failure, end stage renal diseases,
High risk occupational groups hemodialysis
Other special conditions
The whole list is shown in page 10!
To make it easy for adults to decide what vaccines they need to take, the Communicable
Diseases Department at HAAD developed a simple questionnaire/quiz of 16 questions that
can be simply completed by ticking on the correct statements that pertain to your case.
Once completing all answers, you would click on “My Results” button to get what kind of
vaccines you need to have.
Below is an example of the survey rsult you might get if your answers indicated that you are
working in any healthcare setting (Healthcare Professional).
MMR Vaccine You are a healthcare worker and if you may not have immunity 2 doses, 4 weeks apart
to measles, mumps or rubella.
Seasonal Influenza You are a healthcare worker and need to be vaccinated against Single dose every year
Vaccine seasonal influenza once every year.
Travelers
Meningococcal vaccine ACWY135 for travelers to
countries in meningitis belt.
Yellow Fever vaccine for travelers to countries
in the endemic zone.
Rabies vaccine to travelers to high risk areas who
are likely to get in contact with rabies
The following page shows required adults vaccines and indicated groups (the list with de-
tailed scheduled doses is included in HAAD circular to all facilities, available at HAAD website
(Healthcare Facilities - Circulars): http://www.haad.ae/haad/tabid/183/Default.aspx
19.9%
20.0%
15.0% 13.3%
0.0%
1st Degree 2nd Degree 3rd Degree Total
Consanguinity
20.0%
women, with the highest prevalence was
15.0% 11.5%
among Arab expatriate men (10.2%)
10.0%
5.9% 4.8% • Such variations in prevalence reflect
5.0% preferences for different modes of to-
0.0% bacco consumption by nationality, age
Cigarette Medwakh Waterpipe Overall Smoking group, and gender.
• Enforcement of tobacco control laws
and targeted health education pro-
grams are required to reduce tobacco
consumption and related morbidity and
mortality.
By: Kholoud Jamal, Infectious Diseases Clinical Pharmacist, Tawam Hospital; Aqeel Saleem, Infec-
tious Diseases Consultant, Tawam Hospital.
Since their introduction in 1940s, antimicrobial agents have significantly reduced morbidity and
mortality associated with infectious diseases. Antibiotics are relatively so effective, non-toxic, gener-
ally inexpensive, and so easy to use; that they are prone to abuse. Studies suggest that overall, up
to 50% of antibiotic usage is inappropriate. The widespread use of antibiotics in hospitalized and
non-hospitalized patients has been associated with increase in bacterial strains and species that no
longer respond to treatment with most antibiotics. The world is facing a major public health threat
with the spread of antibiotic-resistant bacteria running ahead of production of new antibiotics to fight
them, leading to increased mortality due to multi-drug resistant microorganisms, increased length of
hospital stay, increased C. difficile & other ecological consequences and increased healthcare costs.
Achieving more judicious prescribing of antibiotics requires an understanding of the factors that
promote overuse and the barriers to change, and implementation of effective strategies for chang-
ing behavior. Among providers, most physicians are aware that antibiotics misuse/overuse is a major
risk factor for the development of antibiotic resistance; despite this recognition, unnecessary antibi-
otic prescriptions remain common. The majority of this abuse occurs in treatment of upper respira-
tory infections, for example, pharyngitis, acute otitis media, and acute bronchitis, for which antibiotic
use is not proven to be beneficial. Particularly worrisome is the overuse of fluoroquinolones and
cephalosporins as first-line agents for the treatment of respiratory tract infections. On the other
hand, patients’ lack of knowledge and past experience contribute to increased misuse of antibiot-
ics. Many patients have received antibiotics for viral respiratory illness, and these treatments were
perceived as effective because the infections were generally self-limiting.
Overcoming barriers to more judicious prescribing needs the development of materials to support
change, implementation of effective strategies, and development of supportive structures in health-
care organizations. Those efforts should take into consideration the two sides of this issue, the
patients and prescribers.
The Communicable Diseases Department conducted several activities during the second quarter of
2012. Below are briefs on the main activities took place during that period.
4) Continuation of e-Infectious
Diseases Notifications Workshops
HAAD communicable diseases team conducted two addi-
tional workshops on e-notification of infectious diseases dur-
ing April 2012, targeting Zayed Military and Al Rahba Hos-
pitals in Abu Dhabi. The workshops introduced attendees
to the benefits of the electronic notification system for both
HAAD and the reporting facility in terms of confidentiality,
record keeping, search options, and timeliness of reporting.
It included an enhanced training on the different parts of the
notification process; stressed on the importance of filling the
investigation subforms; and openly discussed noticed gaps.
The UAE hosted the 26th meeting of the Regional Commission of Certification (RCC) of polio
eradication for countries of the Eastern Mediterranean Region of the WHO (EMRO). This is an
annual meeting to discuss the abridged annual update reports on the performance of polio eradi-
cation programs and polio situation in all member states of EMRO. The UAE Abridged Annual Up-
date Report for 2011 , which is a national documentation submitted annually by the UAE National
Certification Committee, was among the accepted reports that were considered adequate by the
WHO/EMRO, and hence UAE maintained the WHO certification of polio eradication.
The Home Screening Program has been expanded to include Ethiopia as the third country after
Indonesia and Sri Lanka. This came by a ministerial decree that is to be effective starting from July
2012. Hence, similar to previous two countries, all applicants coming from Ethiopia for residency
or work in UAE have to do medical screening in their home country, and this should only be done
in any of the GCC approved centers there. Medically fit newcomers from all three countries will be
subjected to re-testing once arriving UAE, and therefore must show the original and copy of the
home-issued fitness certificates at any of the designated screening centers in UAE.
The two health authorities of Abu Dhabi and Dubai met early in April 2012 to discuss all possible
collaborations especially with respect to reporting of infectious diseases. HAAD and DHA shared
their experiences in e-notifications and all documentations and standards related to communica-
ble diseases surveillance. Such kind of collaboration is expected to grow given the sincere inten-
tions of both authorities to make better investment for resources available at their institutes.
The World Health Organization helped the Cambodian Ministry of health investigating an illness that
was initially considered mysterious. The unknown illness was described as a severe respiratory dis-
ease with neurologic symptoms affecting children, mostly under 3 years of age, and generally starts
with high fever. Initially it was announced that 61 of the 62 children admitted in hospitals have died from
the disease, but further investigation showed that 57 out of the 78 cases meeting the case definition
died of the illness.
The investigations into the cases and deaths have lastly concluded that a severe form of hand, foot
and mouth disease (HFMD) was the cause in the majority of cases, where most of the tested samples
were positive for Enterovirus 71 (EV-71) that causes HFMD. It was found that a significant number
of cases had been treated with steroids at some point during their illness, which has been shown to
worsen the condition of patients with EV-71.
Enhanced surveillance for neuro-respiratory syndrome was established, and it is therefore expected
to identify occasional new cases in the coming months. Additionally, the authorities trained the staff on
proper management, and raised public awareness on prevention, identification, and care.
Infection with the human immunodeficiency virus type 1 (HIV-1) requires the presence of a CD4
receptor and a chemokine receptor, principally chemokine receptor 5 (CCR5). Homozygosity for a
32-bp deletion in the CCR5 allele provides resistance against HIV-1 infection. So far, only one per-
son who was infected with HIV-1 and had bone marrow transplant to treat acute myeloid leukemia
has been considered cured of HIV. In his case, the bone marrow donor was not only HIV-negative,
but was homozygous for CCR5 delta32 (i.e. had a rare genetic mutation that blocks HIV from
entering cells).
Recently, researchers at the International AIDS Conference in Washington made presentations on two
HIV-positive men who developed lymphoma. In both cases, their treatment included a bone marrow
transplant, which results in a new immune system. The bone marrow donors did not have HIV, but
did not have the rare genetic variant like in the reported cured case a couple of years back. However,
researchers could not detect any HIV genetic material in the patients’ blood until seventeen months
after the transplants. They say this can be due to the antiretroviral drugs the patients are taking, and
only when they can successfully stop their medication can they be considered cured of HIV. However,
marrow transplantation is not currently considered as a treatment option for HIV.
The difficulty to develop a vaccine against malaria is that it requires producing complex three-dimen-
sional proteins similar to those made by the parasite. Biologists at the University of California, in col-
laboration with a professor of medicine who is a leading expert in tropical diseases, have succeeded in
engineering algal proteins that are structurally similar to the native malaria proteins and elicit antibodies
that recognize Pfs25 and Pfs28 from P. falciparum. When injected into laboratory mice, such proteins
made antibodies that bind the surface of in-vitro cultured P. falciparum sexual stage parasites and
therefore blocked malaria transmission from mosquitoes. Thus, algae are promising organisms for
producing malaria vaccine.
In Abu Dhabi Emirate, brucellosis is a reportable infectious disease that needs to be notified
within one calendar day
The incidence of typhoid/paratyphoid during 2011 was 17 per 100,000 population. However, about
three quarters of the cases were reported based on positive serological testing, which is not sufficient
for diagnosis.
HAAD Case Definition for Reporting
Probable Confirmed
A clinically compatible A clinically compatible case that
case that is epide- is lab confirmed by isolation of
miologically linked to the bacteria from blood, stool, or
a confirmed case in an other specimen.
outbreak.
Below are some figures that show the epidemiology of typhoid/paratyphoid fever during 2011 in the
Emirate of Abu Dhabi, and sources of infection.
9%
majority it was 200 Eastern
based on
serological 150 Western
testing only, and 68
100
in absence of
any epidemio- 50 23 91%
logical link to a
confirmed case. 0
Abu Dhabi Eastern Western
Region
80 21%
Suspected Food
60
Others
40 64%
20
14
34
+
1-
-2
-4
-5
-6
65
<1
5-
-
15
25
35
45
55
6%
300
20%
163
200 129
81 82
57
74% 100
0
2005 2006 2007 2008 2009 2010 2011
Year
Scientific Board
- Dr. Iain Blair (Associate Professor, Community Medicine, UAEU)
- Prof. Tibor Pal (Professor, Department of Medical Microbiology, UAEU)
- Dr. Agnes Sonnevend (Assistant Professor, Department of Medical Microbiology, UAEU)
- Dr. Rayhan Hashmey (Consultant Infectious Diseases, Tawam Hospital)
- Dr. Ahmed Al Suwaidi (Consultant Pediatric Infectious Diseases, Assistant Professor, UAEU)
- Dr. Bashir Aden (Senior Officer, Surveillance Section, HAAD)
- Dr. Jamal Al Mutawa (Manager, External Services Department, HAAD)