8

Self-Learning Kit
Science
Quarter 4 - Week 2

ROSAVIE N. PERALTA
Writer
Science – Grade 8
Self-Learning Kit
Quarter 3 – Week 1
First Edition, 2020

Republic Act 8293, section 176 states that: No copyright shall subsist in any work
of the Government of the Philippines. However, prior approval of the government
agency or office wherein the work is created shall be necessary for exploitation of
such work for profit. Such agency or office may, among other things, impose as a
condition the payment of royalties.

Borrowed materials (i.e., songs, stories, poems, pictures, photos, brand names,
trademarks, etc.) included in this module are owned by their respective copyright
holders. Every effort has been exerted to locate and seek permission to use these
materials from their respective copyright owners. The publisher and authors do not
represent nor claim ownership over them.

Published by the Department of Education

Secretary: Leonor Magtolis Briones
Undersecretary: Diosdado M. San Antonio
Development Team of the Module

Writer : Rosavie N. Peralta

Editors/Reviewers : Marlyn V. Canales, Rosavie N. Peralta
: Mervic C. Celocia, Erah C. Mofar
Illustrator : Rosavie N. Peralta
Layout Artist : Joel R. Capuyan, Rosavie N. Peralta
Management Team : Leah P. Noveras, Ed. D., CESO VI
: Leviticus M. Barazon Jr., Ph.D.
: Lilia R. Ybañez
: Marlyn V. Canales
: Reynilda G. Ramoneda
: Raymond L. Ceniza
: Joel R. Capuyan
: John Orven V. Saldana

Printed in the Philippines by ________________________

Department of Education – Region VII Schools Division of Danao City

Office Address: Sitio Upland, National Road, Danao City, Cebu
Telephone No. (032) 262-6211
Telefax: danao.city@deped.gov.ph
E-mail Address: depeddanaocity.com

i
Note to the Learner

This Self-Learning Kit is prepared for you to learn the specified competencies
based on the Most Essential Learning Competencies (MELC) for Science 8, Quarter 4,
Week 2. It is designed in a simplified structure to help you easily understand the lesson
for the week. It contains the following parts:

I Have Includes an activity that aims to check what you

Known already know about this lesson

I Can Consists of activities that will help you view the

Connect previous lesson and prepare you to the new one

Details the presentation and discussion of the

I Can Learn
concepts that you need to learn in this new lesson

Comprises of activities for independent practice to

I Can Try
check understanding of the new concepts learned

Contains exercises to validate your knowledge and

I Can Assess
understanding of the concepts learned

I Can Do Covers activities and exercises that you can do further

More to enrich your learning

Answer Key Contains the key to correction of all the exercises

Indicates the sources in the development of this Self-

References
Learning Kit (SLK)

ii
Lesson Title The Cell Cycle
Learning Compare mitosis and meiosis, and their role in the cell
Competency division cycle.
Explain the significance of meiosis in maintaining the
chromosome number.
MELC Code S8LT-IVd-16/ S8LT-IVe-17

I Have Known

Directions: Read each question carefully and encircle the letter of the correct answer.

1. In which stage of mitosis does the division of the centromere is observed?

A. anaphase B. metaphase C. prophase D. telophase

2. The duplication of the genetic material happens during which phase?

A. G1 phase B. G2 phase C. mitotic phase D. S phase

3. Your teacher asked you to identify the stage of mitosis from a specimen under the
microscope. You observed that instead of a typical round cell shape, the cell has a
narrow middle part almost separating in its two bulging ends which looks like the number
8. Which important activity does the cell undergo?
A. anaphase B. metaphase C. cytokinesis D. S Phase

4. The correct sequence of steps in cell cycle is __________.

A. anaphase, prophase, interphase, metaphase, telophase.
B. interphase, anaphase, metaphase, prophase, telophase.
C. interphase, prophase, metaphase, anaphase, telophase.
D. prophase, metaphase, interphase, anaphase, telophase.

5. In humans, mitosis is important because it helps in the __________.

A. formation of sex cells. C. growth and repair of tissues.
B. death of unnecessary cells. D. maintain healthy number of sex cells.

6. Which of the following statements is TRUE about meiosis?

A. It allows organism to grow and repair tissues.
B. It allows organism to reproduce asexually.
C. It allows organism to reproduce sexually.
D. It allows organism to promote genetic diversity.

7. In which stage of meiosis do synopsis and crossing over occur?

A. anaphase II B. interphase I C. metaphase II D. prophase I

1
8. Meiosis is a type of cell division that produces ______.
A. chromosomes B. DNA C. sex cells D. zygote

9. Which of the following cells undergo meiosis?

A. cardiac muscle cells C. skin cells
B. red blood cells D. sperm cells

10. How many daughter cells are produced after meiosis?

A. 2 B. 4 C. 23 D. 46

I Can Connect

In your Grade 7, you have learned the different parts and functions of the cell.
Can you still identify them? Use the following figure to let you know how much you have
learned from the previous grade level.

A. Directions: Label the parts of the cell.

Note: Please check your answers using the answer key

on page 18.

How many have answered correctly?

Congratulations for the job well done.

https://urlshortner.org/XU2H3
Figure1: Animal Cell

Parts and Function of the Cell

B. Directions: A good analogy to consider with cell and its function is the school. Different
organelles can be used to describe different facilities and/ or personnel of the school. Pair
the words by filling in the blanks with the appropriate word. Choose your answers from the
word bank.
1. mitochondria: _________________ = cafeteria: food
2. principal: head = _______________: control
3. vacuoles: _____________________= locker: safekeeping
4. security guard: monitors safety = ___________________________: protection
5. office: releasing/ receiving = _________________________: packaging/ transporting
WORD BANK
- Storage - powerhouse - nucleus
- Cell membrane - ribosomes - golgi apparatus

2
 I Can Learn

Cells are building blocks of life. This implies that all living organisms are composed
of cells. Cells undergo different stages of cellular development which is presented in the
cell cycle.

In this lesson, you will be able to understand the role of each cell organelle in the
reproduction of cell. You will also learn about the similarities and differences of mitosis
and meiosis and their role in the cell division cycle.

The Cell Cycle

A repeating sequence of cellular growth and division during the life of an

organism is known as the Cell Cycle.

Figure 2: The Cell Cycle

https://o.quizlet.com/aBZV3fUfGBWyQWNg-akvQg_b.jpg

The figure above shows the cell’s activities in the Cell Cycle. The entire cycle is
divided into main stages, Interphase, and M-Phase where M stands for either Mitosis or
Meiosis.

The Interphase

During interphase, the cell grows, accumulates nutrients, and replicates genetic
material – all important events that prepare the cell for division. It is the longest phase in
the cell cycle. The interphase is divided into three stages:

Stage 1 G1 (Growth or Gap 1) Phase

 Rapid growth of the young cells happen in this stage until the normal size is
attained.
 Organelles start to double in number.
 Proteins are produced such as the enzymes needed in S Phase.
 This is the longest phase in most cells.

3
 Stage 2
S (Synthesis) Phase

 The DNA, the main composition of the chromosomes inside the nucleus of the cell
doubles at this stage by a process called replication.
 At the end of this stage, each chromosome is made up of two sister chromatids
attached at the centromere.

Stage 3 G2 (Growth) Phase

 Preparation for the actual cell division.

 Assembly of proteins, such as microtubules, which are hollow protein fibers that
cause the chromosomes to move during cell division.

After the three stages of the interphase, the cell is now ready for the actual cell
division.

The M-Phase

M-Phase is classified into two types namely; mitosis and meiosis.

 MITOSIS – is a process where a single cell divides into two identical daughter cells.
 MEIOSIS – is a process where sex cells divide to form four haploid cells.

What is the difference between Mitosis and Meiosis?

Below is the discussion on how mitosis and meiosis differ from each other.

Figure 3: Comparison between mitosis and meiosis

4
 MITOSIS – is a process where cells divide into two nuclei with identical genetic
material with the same number of chromosomes similar to the parent cell, thus a diploid
(2n)parent cell containing two sets of chromosomes will result in two diploid daughter
cells after mitosis.

Mitosis plays an important part in the development of embryos, and it is important

for the growth and development of our bodies as well. Mitosis produces new cells, and
replaces cells that are old, lost, or damaged.

Mitosis is a continuous process, but it is traditionally divided into four stages:

prophase, metaphase, anaphase, telophase.

The Stages of Mitosis

Stage 1 Prophase

 the long thread-like chromatids start to coil and become visible under the
compound microscope as individual chromosomes
 each chromosome at this stage contains two identical sister chromatids, the result
of DNA synthesis
 the nuclear membrane dissolves and the spindle fibers are formed
 centrioles migrate at opposite poles
 the nucleolus disappears

Stage 2
Metaphase

 chromosomes move and align themselves at the center of the cell called
metaphase plate
 Spindle fibers connect each chromosome on its centromere to the centrioles
located at opposite poles

Stage 3 Anaphase

 the proteins that bind the two sister chromatids of each chromosome divide
 chromosomes separate and are pulled toward the opposite poles as a result of
the shortening of the spindle fiber.

Stage 4 Telophase

 the chromatids (now called chromosomes) are located at the opposite poles
 nuclear membrane forms around each set of chromosomes which start to uncoil
 the spindle fibers disappear
 each chromosome in a daughter cell is composed only of one chromatid
 Two new daughter cells are formed.

After the division of the nucleus called karyokinesis, the cytoplasm starts to
divide, a process called cytokinesis. Cytokinesis in animal cells and other cells that lack
cell walls starts at the exterior of the cell moving inwards until the cell is divided into two
cells. This process is called cleavage furrow formation. In plant cells and other cells with

5
cell wall, cytokinesis starts at the middle of the cell and moves outward by a process
called plate formation.

https://urlshortner.org/UsBLa
Figure 4: Mitotic Division

MEIOSIS – is a process where a single cell divides twice to produce four cells
containing half the original amount of genetic information producing haploid cells. Sex
cells or reproductive cells known as gametes (sperm cells in males, egg cells in females)
undergo meiosis.

Meiosis is divided into two successive cell divisions. The first part is called meiosis I
called reduction division reduces the number of chromosomes from diploid (2n) to
haploid (n) number. The second part, meiosis II, is very similar to mitosis, thus called
equatorial division. Both meiosis I and meiosis II are subdivided into four stages.

MEIOSIS 1

Stage 1 Prophase I

 Chromosomes start to coil and shorten

 The nuclear envelope disintegrates
 Homologous chromosomes pair by a process called synapsis.
 Exchange of genetic material (crossing over) may occur between homologous
chromosomes when the chromatids are broken. Crossing over contributes to
genetic diversity.

Stage 2
Metaphase I

 The paired homologous chromosomes align at the metaphase plate

 The chromosomes in pair are attached to the spindle fiber

Stage 3
Anaphase I

 Homologous chromosomes separate.

 The chromosomes move toward opposite poles of the cell by the spindle fibers.

6
 Stage 4 Telophase I

 Chromosomes reach opposite poles.

 In most organism, the nuclear membrane forms. This is followed by cytokinesis.

MEIOSIS 11

Stage 5 Prophase II

 The nuclear membrane disintegrates.

 New spindle fibers are formed around the chromosomes.

Stage 6 Metaphase II

 The chromosomes align at the metaphase plate and are attached to their
chromosomes to the spindle fibers.

Stage 7
Anaphase II

 Each chromosome is divided into two sister chromatids

 The chromatids (now called chromosomes) move to opposite poles.

Stage 8
Telophase II

 Nuclear membrane is formed around each set of chromosomes.

 Spindle fibers disintegrate.
 The cell undergoes cytokinesis.

Figure 5: the cellular activities in each stage of meiosis.

7
 The following summarizes the comparison between mitosis and meiosis based on
the given features.

Comparison Between Mitotic and Meiotic Cell Division in Animal Cells

Feature Mitosis Meiosis

Cell where it occurs Body Cells Sex Cells (gametes)
(sperm cells – males,
Egg cells – females)
Final chromosome Diploid, 2n, (46 chromosomes Haploid, n, (23 chromosomes in
number in humans) humans)
Number of cell One division occurs during Two divisions occur in meiosis:
divisions per DNA mitosis. meiosis I and II
replication
Number of cells Two identical cells (2n) are Four haploid cells (n) are formed.
formed per cycle formed.
Daughter cells The daughter cells are The daughter cells are not
genetically identical. genetically identical due to
crossing over.
Function Growth, development, repair Gamete production needed for
and maintenance of tissues, sexual reproduction
asexual reproduction
Source: Exploring Life Through Science Series published by Phoenix Publishing House

Meiosis is the main event involved in the process of gamete formation called
gametogenesis. Gamete formation in males is called spermatogenesis while gamete
formation in females is called oogenesis. The gametes produced in spermatogenesis are
the sperm cells while in oogenesis are the egg cells or ova (singular: ovum) Both
spermatogenesis and oogenesis are involved in the same steps of meiosis, the resulting
daughter cells are haploid cells. The two processes differ, however, in the number of
gametes produced because four functional sperm cells are produced in
spermatogenesis while
only one functional
ovum is produced in
oogenesis. The other
haploid cells
produced are polar
bodies as shown in the
illustration in Figure 6.

Figure 6:
Spermatogenesis vs. OOgenesis

https://tinyurl.com/ypdtkxwx

How do meiosis and sexual reproduction produce genetic variability?

8
 Genetic variability among
organisms is essential for survival and
reproduction in a changing
environment.

The sperm cells and egg cells

produced after gametogenesis are
haploid cells. This number of
chromosomes, however, becomes a
diploid during the process of fertilization.

In mathematical expression,
Haploid (n) + haploid (n) = diploid (2n)
For instance, human egg cells and
sperm cells are haploid (n) containing
only 23 chromosome each, so, if 23
chromosomes from an egg cell is
fertilized by 23 chromosomes from a Fig. 7: The fusion of sperm and egg cells during
sperm cell, it gives a total of 46 fertilization produces diploid zygote.
chromosomes, a diploid cell.

Thus, in organisms that undergo sexual reproduction, the diploid number of

chromosomes (46 in humans) is restored during zygote formation (fertilized egg). How
about other living organisms? Do they have different number of chromosomes? The table
below summarizes the chromosome numbers of other forms of life.

https://tinyurl.com/2tx8r329 https://tinyurl.com/ak84b3k5
Figure 8: Chromosome Number of some domestic animals Figure 9: Chromosome number of
Some Common Organisms

The process of meiosis is an important event because it produces genetic variations

among sexually reproducing organism. Genetic variations are the reasons why no two
individuals are identical. Because of these genetic variations, every individual is unique
when compared to others. The parts of genetic information that give specific traits are
called genes. In diploid (2n) cells, each gene is present in two copies, one from each
parent on the specific homologous chromosome. The table below shows the number of
chromosomes of domesticated animals.

9
What happens when something goes wrong during meiosis?

Meiosis is a type of cell division that makes sex cells, or gametes. Errors during
meiosis can lead to mutations in gametes. Defective gametes that undergo fertilization
may result in miscarriages or ultimately lead to genetic disorders. The most likely mistake
to occur during meiosis is chromosomal non-disjunction, which results in the wrong
number of chromosomes in a sex cell.

Non-disjunction

Non-disjunction occurs when the chromosomes fail to separate properly as the cell
divides. The results of non-disjunction are gametes containing the wrong number of
chromosomes. In humans, a sperm or egg cell may contain an extra chromosome (for a
total of 24) or may be missing a chromosome (totaling 22). This would lead to a person
with 47 chromosomes or 45 chromosomes instead of the normal 46. A pregnancy
occurring after non-disjunction could also result in a miscarriage or stillbirth.

Non-disjunction of Human Sex Cells

If the extra or missing chromosome is a sex chromosome (chromosome 23, X and Y),
the results tend to be less severe than in non-sex chromosomes (chromosomes 1 through
22). Usually, males have the sex chromosomes XY and females have the sex
chromosomes XX. Syndromes resulting from non-disjunction of the sex chromosomes
include:

 Klinefelter syndrome (male with an extra X),

 Jacob’s syndrome (males with an extra Y) XYY syndrome
 Turner's Syndrome (female missing the second X chromosome)
 Superfemale – a trisomy X, (female with an extra X chromosome)

Non-disjunction of Human Autosomes

If the non-sex chromosomes (autosomes) fail to separate properly, the results are
usually fatal, and the pregnancy is not carried out. When autosomal non-disjunctions do
lead to birth, the individual will carry a third chromosome.

 Down’s syndrome – trisomy of chromosome 21.

 Patau’s syndrome - trisomy of chromosome 13.
 Edward’s syndrome - trisomy of chromosome 18.

Other more severe chromosomal abnormalities that are rarely carried to term
include extra copies of chromosomes 15, 16, and 22.

10
 I Can Try

Activity 1: Spot Me!

A. Directions: Identify the pictures based on stages of the cell cycle. Use the letters below
to identify each stage. The first one is done for you. Write your answer on the blank.

1. Interphase - ______D_______
2. Prophase - _______________
3. Metaphase - _______________
4. Anaphase - _______________
5. Telophase - _______________

Activity 2: The Venn D!

B. Directions: Fill in the Venn diagram with the correct facts about mitosis and meiosis
listed in the word bank. Write your answers on you’re the Venn diagram.
WORD BANK
- Makes 4 daughter cells - interphase
- Makes 2 daughter cells - body cells
- Cells are haploid - cellular reproduction
- Cells are diploid - crossing over
- 2n - synapsis
- n - cytokinesis
- creates gametes - reduced number of chromosomes

11
Activity 3: Try to Fill
C. Directions: Given the equation n (haploid) + n (haploid) = 2n (diploid), fill in the table
with the correct number of chromosomes of the given organism.
Please refer to figure 8 & 9.

Name of Organism Haploid (n) Diploid (2n)

1. Donkey

2. Cat

3. Camel

4. Dog

5. Sunflower

I Can Assess

A. Directions: Read each item carefully and write the letter of the correct answer on your
paper.

1. In which stage of meiosis do synapsis and crossing over occur?

A. anaphase II B. interphase I C. metaphase II D. prophase I

2. Humans have 46 chromosomes in their body cells. After mitosis, we expect that the
daughter cells would each have a total of ________ chromosomes. In sex cells undergoing
meiosis I, we expect that the two daughter cells would contain ______ chromosomes, and
after meiosis II _________ chromosomes.
A. 23, 23, 23 B. 46, 12, 12 C. 46, 23, 23 D. 46, 46, 46

Use the following figure to answer questions 3 – 4.

3. If the circle of the cell cycle also represents the time

an average cell spends in each phase, which of the
following is correct?
A. Cells spend most of their time in the mitosis phase.
B. Cells spend more than 75% of their time in
interphase.
C. Cells spend approximately 50% of their time in
D. Cells spend approximately 75% of their time in

4. Which of the following phases in the cell cycle shown represent interphase?
A. phases M, G1, and S C. phases G1, S, and G2
B. phases S, G2, and M D. phases G1 and G2

12
5. Which of the following accurately describes the actions occurring during the
phase entitled G1?
A. Each chromosome is duplicated; each chromosome results in two sister
chromatids attached at a centromere.
B. The chromosome number is halved in preparation for cell division.
C. The cell enlarges, proteins are increased, and organelles duplicated.
D. Cell reaches maximum size and adds more proteins.

6. Which phases of the cell cycle represent interphase?

A. phases M, G1, and S C. phases G1, S, and G2
B. phases S, G2, and M D. phases G1 and G2

7. Comparing mitosis and meiosis, which of the following is an accurate statement?

A. Most plant and animal cells undergo mitosis however only animals are able to
perform meiosis.
B. Most plant and animal cells undergo mitosis however only plants are able to
perform meiosis.
C. Most plant and animal cells undergo mitosis; both plants and animals are
able to perform meiosis.
D. Plants perform mitosis while animals perform meiosis.

8. Which of the following would result to Down’s syndrome?

A. Trisomy of chromosome 15 C. Trisomy of chromosome 18
B. Trisomy of chromosome 21 D. Trisomy of chromosome 12

9. Which phase of cell division does the picture represent?

A. Prophase
B. Metaphase
C. Anaphase
D. Telophase

10. Which of the following sex chromosomes determine superfemale?

A. XXY B. XXX C. XYY D. YYY

13
B. Directions: Determine whether the given cell activities happen during mitosis or meiosis
by placing check (√) on the appropriate column then, identify which stage of the cell
division is described. The first one is done for you.

Cell Activities Mitosis Stage Meiosis Stage

Cell undergoes rapid growth. √ Interphase √ Interphase

Chromosomes align at the

center

Crossing over occur

Four haploid cells are produced

Two sister chromatids of each

chromosome divide.

I Can Do More

Directions: Illustrate the 4 stages of mitosis. Suggested materials to be used are the
following: ¼ illustration board, yarn, glue, or other materials available at home. Be
creative.

Criteria for Scoring:

Creativity Resourcefulness Impact Timeliness Total

Shows Shows artists’ Shows the over- Artwork

ingeniousness capability of all appearance submitted on or
of the devising ways of the artwork before the
imagination and using that impinges deadline
and originality indigenous or viewers interest
of the artwork readily available
materials

15 points 15 points 10 points 10% 50 points

14
 15
I Can Connect
I Can Try I Can Try:
A.
C.
1. D
2. A,F Organism Haploid Diploid
3. C Donkey 31 62
4. E
5. B Cat 19 38
Camel 37 74
B.
Dog 39 78
MEIOSIS:
- Makes 4 daughter cells Sunflower 17 34
- Cells are haploid
- n
- creates gametes I Have Known
- crossing over
1. B
- synapsis
- reduced number of chromosomes 2. A
3. C
BOTH:
- interphase 4. C
- cellular reproduction Can Assess. 5. C
- cytokinesis together with the I 6. A
submitted
MITOSIS: 7. D
and this should be
- makes 2 daughter cells
the one to check 8. C
- cells are haploid
- body cells
The teacher will be 9. D
- growth I Can Do More 10. B
Answer Key
 References

 https://byjus.com/biology/significance-of-meiosis/
 https://urlshortner.org/TCiIX
 https://education.seattlepi.com/can-happen-meiosis-goes-wrong-5596.html
 https://tinyurl.com/4v7ee9pu
 https://urlshortner.org/XU2H3
 https://tinyurl.com/ypdtkxwx
 https://tinyurl.com/2tx8r329
 https://tinyurl.com/ak84b3k5
 Ferriols-Pavico, Ma. Josephina, et.al. Exploring Life Through Science Series. Phoenix
Publishing House

For inquiries or feedback, please write or call:

DepEd – Danao City Division –Curriculum Implementation Division
Sitio Upland, National Road, Poblacion, Danao City, Cebu
Email Address: danao.city@deped.gov.ph
Website: depeddanaocity.com
Telephone No.: (032) 262-6211

16
 Republic of the Philippines
Department of Education
REGION VII
SCHOOLS DIVISION OFFICE OF DANAO CITY

WEEKLY LEARNING PLAN IN SCIENCE GRADE 8

QUARTER 4-WEEK 2
Learning Competency/ies Compare mitosis and meiosis, and their role in the cell
division cycle. S8LT-IVd-16
Explain the significance of meiosis I in maintaining the
chromosome number. S8LT-IVe-17
Learning Tasks/Learning Resources
A. Teacher’s Tasks:
1. Perform daily routine
 Prayer
 Greetings
 Attendance Check
2. Administer pre-test
 Let the leaners answer “I Have Known”, (SLK pp.1-2)
3. Conduct review
 Review concepts on how to explain ingestion, absorption, assimilation, and excretion.
Refer to “I Can Connect”, (SLK p.2)
4. Deliver the new lesson
 Discuss the new lesson by following the activities found in “I Can Learn”, (SLK pp. 3-10)
5. Check learner’s understanding
 Let the leaners do activities in “I Can Try”, (SLK pp.11-12)
6. Validate learning
 Let the leaners answer “I Can Assess”, (SLK pp.12-14)
7. Provide enrichment activity
 Let the leaners perform activities in “I Can Do More”, (SLK p.14)
B. Learner’s Tasks:
1. Answer “I Have Known”, (SLK pp.1-2) and check your answer. Refer to Answer Key p.15.
2. Read and review concepts in “I Can Connect”, (SLK p.2) see answer key on page 15.
3. Read and understand the new lesson presented in “I Can Learn”, (SLK pp. 3-10)
4. Do activities in “I Can Try”, (SLK pp.11-12). Check your work by referring to the answer key
found in p. 15.
5. Answer “I Can Assess”, (SLK pp.12-14) and submit your answer sheet.
6. Perform activities in “I Can Do More”, (SLK p.14). Submit your answer sheet.

Prepared by:
ROSAVIE N. PERALTA
Writer

Contact No: 09612416621

Email Account: rosavie.peralta@deped.gov.ph
FB Account: Rosavie Peralta
17
Assessment

Answer key:

A. 1. D

2. C

3. B

4. C

5. C

6. C

7. C

8. B
9. B

10. B

B.

Cell Activities Mitosis Stage Meiosis Stage

Cell undergoes rapid growth. √ Interphase √ Interphase

Chromosomes align at the center √ Metaphase √ Metaphase I &

Metaphase II

Crossing over occur √ Prophase I

Four haploid cells are produced √ Telophase II

Two sister chromatids of each √ Anaphase √ Anaphase I &

chromosome divide. Anaphase II

18
19
20
21