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General Biology 1
Quarter 1 – Module 1:
Cell: Basic Unit of Life
General Biology 1 – Grade 12 (SHS STEM)
Quarter 1 – Module 1: Cell: The basic Unit of Life
First Edition, 2021
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General Biology 1
Quarter 1 – Module 1:
Cell: The Basic Unit of Life
Introductory Message
For the facilitator:
As a facilitator, you are expected to orient the learners on how to use this
module. You also need to keep track of the learners' progress while allowing them to
manage their own learning at home. Furthermore, you are expected to encourage
and assist the learners as they do the tasks included in the module.
As a learner, you must learn to become responsible of your own learning. Take
time to read, understand, and perform the different activities in the module.
1. Use the module with care. Do not put unnecessary mark/s on any part of the
module. Use a separate sheet of paper in answering the exercises.
2. Don’t forget to answer Let Us Try before moving on to the other activities.
3. Read the instructions carefully before doing each task.
4. Observe honesty and integrity in doing the tasks and checking your answers.
5. Finish the task at hand before proceeding to the next.
6. Return this module to your teacher/facilitator once you are done.
If you encounter any difficulty in answering the tasks in this module, do not
hesitate to consult your teacher or facilitator. Always bear in mind that you are not
alone. We hope that through this material, you will experience meaningful learning
and gain deep understanding of the relevant competencies. You can do it!
2
Let Us Learn
This module was designed for you, the learners. It is to facilitate you to learn
the appropriate knowledge and skills as you go through a series of worthwhile
activities. The lessons are arranged sequentially in this course to ease understanding
and mastery. This module will help you in your learning the key concepts on topics
and immersed you in various activities, and hands – on tasks that will help you
answer the questions pertaining to the cell theory, structure and functions.
Let Us Try!
Read each item carefully. Select the best answer and write only the letter of your
choice on a separate piece of paper.
4. It contain the cell’s hereditary information and controls the cell’s growth and
reproduction. Which of the following cellular structure is called as the control
center.
A. Cell Membrane C. Nucleolus
B. Nucleus D. Organelle
5. This organelle plays a major role in breaking down nutrients and generating
energy-rich molecules for the cell . Which of the following organelles serves as
venue for cellular respiration and is known as the powerhouse of the cell?
A. Chromosome C. Nucleus
B. Mitochondrion D. Nucleolus
6. When you look at an unknown cell under the microscope, you noticed the
presence of a cell wall and membrane-bound organelles. What kind of cell you
can conclude?
A. animal cell C. plant cell
B. bacterial cell D. virus
9. When there is an abnormal shape in the human nerve, there is a defect in which
of the following cell parts?
A. cell wall C. nucleus
B. cytoskeleton D. ribosome
10. Which of the following property that distinguishes cells in domain Bacteria from
those in domain Eukarya?
A. cell wall C. flagella
B. DNA D. membranous organelles
11. Which of the following statements best describes the difference between
prokaryotes and eukaryotes?
I. Prokaryotes do not have membrane –bound organelles that eukaryotes have
II. Prokaryotes have cell walls while eukaryotes have none.
III. Prokaryotes are unicellular while eukaryotes are multicellular
A. I only C. III only
B. II only D. I and II only
12. Which of the following structures is NOT found in prokaryotes but present in
eukaryotes?
A. cell membrane C. DNA
B. Cell Wall D. nuclear membrane
14. The following activities are performed by both unicellular and multicellular
organisms EXCEPT one. Which is performed only by multicellular organism?
A. Each cell reproduces and grows
B. The cell goes through the cell cycle
C. The cell reproduces sexually or asexually
D. Each kind of cell specializes in a specific function.
Lesson
Let Us Study
In your previous grade levels, you have learned about the characteristics of a cell –
its parts and the functions of each part. In this lesson, we will learn how cells were
first discovered, how the cell theory was developed, and the main components of the
cell theory. To enhance learning, you will be doing activities around cell theory for
deeper understanding of this lesson.
The unified theory was proposed by botanist Matthias Schleiden and zoologist
Theodor Schwann who were both studying tissues in the late 1930’s. The unified cell
theory states that: all living things are composed of one or more cells; the cell
is the basic unit of life; and new cells arise from existing cells. Rudolf Virchow
later made important contributions to this theory.
The cell theory proves that cells are common to all living things and the best source
of information about life. And because cells come from other cell, it is possible for
scientists to study growth and reproduction and all other functions of living things.
All living things are made up of cells. Cell is the smallest unit of living things and the
smallest part of the organism that retains characteristics of the entire organism. For
example, a cell can take in fuel, convert it to energy, and eliminate metabolic wastes,
just like the organism as a whole can. The structures inside the cell cannot perform
these functions on their own, so the cell is considered the lowest level.
A living thing, whether made of one cell (like bacteria) or many cells (like a human),
is called an organism. Several cells of one kind that interconnect with each other
and perform a shared function form tissue; several tissues combine to form an organ
(your stomach, heart, or brain); and several organs make up an organ system (such
as the digestive system, circulatory system, or nervous system). Several systems that
function together form an organism (like a human being).
Direction: Read the storyboard below and complete the graphic organizer.
Source: https://www.storyboardthat.com/fr/storyboards/s162169/bio-comic-strip
In this graphic organizer, (1) indicate the contribution of each scientist in their
respective box, (2) state the three postulates of the Cell Theory, and (3) explain how
the invention of the compound microscope contributed to the development of the Cell
Theory.
Robert Anton van What are the main points of the Cell
Leeuwenhoe
Hooke k
Theory?
1.
2.
3.
16 16
All three postulates of the Cell Theory are equally important – the postulates support
the theory that the functions necessary for life occur in the cell. Findings since the time
of the original Cell Theory have enabled scientists to "modernize" the theory, including
points related to biochemistry and molecular biology. The modern version of the Cell
Theory includes:
Note: You may use the template below or use a storyboard creator online in making
your comic strips
Your comic strip will be rated based on the rubric below. Please be guided
accordingly.
Let Us Remember
Lesson
Cell Structure and
2 Functions
Let Us Study
Learned in our Biology class that an organelle is a membrane bound structure found
within a cell and they make up the subunits of the cell. In this lesson, we will
scrutinize what is inside a cell. We will describe the structures of the organelles and
subcellular organelles and how they function. We will also identify whether such
organelle is found in plants or animals.
Plant Cell Animal Cell
An organelle is a cell’s internal organ – they can be found within the cell. Imagine
that the organelles are the smaller offices/rooms within the factory, which has
specialized ability to help other offices/rooms within the factory, helping in the
carrying out of specific task or function. These organelles are in the cytoplasm – a
viscous liquid found within the cell membrane where organelles can be found and
where most actions in the cell happened.
Direction: Compare the cell to a city. Identify which organelle corresponds to the
function of a city icon below. Write your answer on a separate paper.
Lesson
Prokaryotic and Eukaryotic
3 Cells
Let Us Study
In lesson 2, you have learned about the cell structure and function of major and
subcellular organelles. In this next topic, you will learn on prokaryotic and
eukaryotic cells according to their distinguishing features.
Did you know that cell is the basic unit of life? All living organism are composed of
one to trillions of cells that work together to carry out life processes. Cells are
classified into two types. Prokaryotic cells and eukaryotic cells.
Are you now ready to learn how these two kinds of cells differ from each other? So,
let’s get started and enjoy!
Knowing our Cells
All life on Earth consists of either eukaryotic cells or prokaryotic cells. Prokaryotes
were the first form of life. Scientists believe that eukaryotes evolved from prokaryotes
around 2.7 billion years ago.
Cells fall into one of two broad categories: prokaryotic and eukaryotic. The
predominantly single-celled organisms of the domains Bacteria and Archaea are
classified as prokaryotes (pro– = before; –karyon– = nucleus). Animal cells, plant
cells, fungi, and protists are eukaryotes (eu– = true).
All cells, whether prokaryotic or eukaryotic, share these four features:
1. DNA
2. Plasma membrane
3. Cytoplasm
4. Ribosomes
Eukaryotic Cell Structure
Eukaryotic cells are cells that contain a membrane-bound nucleus and many
internal membranes called organelles. The eukaryotic cell has three main parts as
follows.
a. Cell membrane that separates the intracellular space from the outer space
physically delimiting the cell.
b. Cytoplasm, the interior portion filled with cytosol (the aqueous fluid inside
the cell and contains all the organelles
c. Nucleus, covered by double membrane that contains the genetic material.
d. Ribosomes are molecular machines that synthesize proteins.
Prokaryotic Cell Structure
A prokaryote is a simple, single-celled organism that lacks a nucleus and
membrane-bound organelles.
a. The plasma membrane is an outer covering that separates the cell’s interior
from its surrounding environment.
b. Cytoplasm consists of the jelly-like cytosol inside the cell, plus the cellular
structures suspended in it. In eukaryotes, cytoplasm specifically means the
region outside the nucleus but inside the plasma membrane.
c. DNA is the genetic material of the cell.
d. Ribosomes are molecular machines that synthesize proteins.
CELLS
ALIKE
DIFFERENCES
Let Us Remember
In Lesson 3, you have learned that the cell is the basic unit of life, responsible
for all biological activities of the living being whether its prokaryote or eukaryote.
Both of these cells vary in their role, like prokaryotes are the old type of cells hence
they lack a proper nucleus and other organelles too, which are very well present in
eukaryotes, as these are advanced cells.
● Prokaryotes are single-celled organisms that lack a membrane-bound
nucleus, mitochondria, and all other organelles.
● Eukaryotes are organisms with cells that contain membrane-bound nucleus
and other membrane-bound organelles.
Let Us Assess
Read the questions carefully. Choose the best answer and write it on a separate sheet
of paper.
1. What famous discovery did Anton Van Leeuwenhoek make with his homemade
microscope?
A. animalcules
B. microscope and telescope
C. all plants are made of cells
D. bacteria on dental scrapings
2. What part of the cell theory did Schleiden and Schwann disagree on?
A. the first part C. the second part
B. the third part D. the fourth part
3. The cell Theory postulate that cell comes from free existing cells .Name the
scientist that proved all cells come from other cells.
A. Hooke
B. Schwann
C. Schleiden
D. Virchow
5. Which cell organelles provides temporary storage of food, enzymes, and waste
products?
A. Chloroplast C. Ribosome
B. Nucleus D. Vesicle
6. Which organelles is firm, form a protective structure and gives the cell its shape
for plants, fungi, most bacteria, and some protists?
A. Cell Wall C. Golgi apparatus
B. Cytoskeleton D. Mitochondrion
7. It digests excess or worn-out cell parts, food particles and invading viruses or
bacteria. Which of the following is considered as “suicide bags” of the cells?
A. Flagellum C. Nucleolus
B. Lysosome D. Ribosome
8. It is the biggest structure in the nucleus of eukaryotic cells and the site where
ribosomes are made.
A. Cytoskeleton C. Mitochondrion
B. Ribosome D. Nucleolus
9. Which are small bumps located on portions of the endoplasmic reticulum?
A. Lysosome C. Ribosome
B. Peroxisome D. Vesicle
12. Which two cell structures in the box below are present in eukaryotes but not in
prokaryotes
Nucleolus
Cell membrane
Nuclear materials
A. 1 and 3 C. 2 and 3
Nuclear
B. 1 and 4 d. 2 and 4
membrane
13. Is it TRUE that (I) prokaryote have nucleus, while (II) eukaryotes do not have?
A. I but not II C. II but not I
B. Both I and II D. Neither I nor II
Let Us Enhance
Let Us Reflect
Early evidence for the cell theory was provided by German scientists. In 1838, the
botanist Matthias Schleiden concluded that all plants are composed of cells. A year
later, the zoologist Theodor Schwann came to the same conclusion about animals.
In 1855, Rudolf Virchow, a physician who had been studying how disease affects
living things, reasoned that cell come only from other cells. Over the years, modern
scientists have gathered much additional evidence that strongly supports the cell
theory.
Let Us Practice More Let Us Practice More
B. A.
Let Us Practice Let Us Assess Let Us Try
Working Site -> Cytoplasm 1. D 1. A
2. B 2. D
CEO -> Nucleus 3. D 3. B
4. D 4. B
Workers -> Ribosome
5. D 5. C
Assembly Line -> Endoplasmic Reticulum 6. A 6. A
7. B 7. A
Packaging Department -> Golgi Apparatus 8. B 8. D
9. C 9. D
Delivery Team -> Cell Membrane
10. C 10. D
Cleaning Crew -> Lysosome 11. D 11. A
12. B 12. D
Power Plant -> Mitochondria 13. B 13. D
14. B 14. D
15. D 15. D
Answer Key
References:
https://resources.saylor.org/wwwresources/archived/site/wp-
content/uploads/2010/11/Wiki-Cell-Theory.pdf
Creative Commons Attribution-Share Alike 3.0 Unported
http://creativecommons.org/licenses/by-sa/3.0/
https://www.storyboardthat.com/fr/storyboards/s162169/bio-comic-strip
http://www.sc.chula.ac.th/courseware/2303101j/VIII-Cell.pdf
http://www.sc.chula.ac.th/courseware/2303101j/VIII-Cell.pdf
https://bio.libretexts.org/Bookshelves/Human_Biology/Book%3A_Human_Biology
_(Wakim_and_Grewal)/05%3A_Cells/5.06%3A_Cell_Organelles
https://2012books.lardbucket.org/books/an-introduction-to-nutrition/index.html
Creative Commons by-nc-sa 3.0
Prokaryote and Eukaryotes Cell. Accessed July 20, 2020 from:
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QbsqKTwBg&q=prokaryotic+cell+structure&oq=prokaryote+cell&gs_lcp=CgZ
wc3ktY
Difference of Prokaryote and Eukaryotes Cell. Accessed July 22, 2020 from:
https://courses.lumenlearning.com/boundless-biology/chapter/eukaryotic-
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Type of Cells: Prokaryote and Eukaryotes Cell. Accessed July 20, 2020
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