Life Sciences Gr12 QP June2022 - English

NATIONAL
SENIOR CERTIFICATE
GRADE 12
JUNE 2022
LIFE SCIENCES
MARKS: 150
TIME: 2½ hours
This question paper consists of 16 pages.

2 LIFE SCIENCES (EC/JUNE2022)
INSTRUCTIONS AND INFORMATION
Read the following instructions carefully before answering the questions.
1. Answer ALL the questions.
2. Write ALL the answers in your ANSWER BOOK.
3. Start the answer to EACH question at the top of a NEW page.
4. Number the answers correctly according to the numbering system used in this
question paper.
5. Present your answers according to the instructions of each question.
6. Do ALL drawings in pencil and label them in blue or black ink.
7. Draw diagrams, tables or flow charts only when asked to do so.
8. The diagrams in this question paper are NOT necessarily drawn to scale.
9. Do NOT use graph paper.
10. You may use a non-programmable calculator, protractor and a compass where
necessary.
11. Write neatly and legibly.
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(EC/JUNE2022) LIFE SCIENCES 3
SECTION A
QUESTION 1
1.1 Various options are given as possible answers to the following questions.
Choose the answer and write only the letter (A–D) next to the question
numbers (1.1.1 to 1.1.10) in the ANSWER BOOK, for example 1.1.11 D.
1.1.1 The central nervous system is made up of the …
A autonomic and peripheral nervous systems.

B cranial and spinal nerves.
C sympathetic and parasympathetic nerves.
D brain and spinal cord.
1.1.2 Which ONE of the following involves the development of the young
inside the uterus of the mother and where it receives nutrients
through the placenta?
A Ovipary
B Vivipary
C Ovovivipary
D Amniotic egg
1.1.3 Where are sperm cells in humans temporarily stored?
A Epididymis
B Vas deferens
C Urinary bladder
D Prostate gland
1.1.4 A patient experiences slight visual and speech disturbance after a

serious head injury. Which section of the brain has possibly been
damaged?
A Cerebrum
B Cerebellum
C Hypothalamus
D Medulla oblongata
1.1.5 Contraceptive pills which prevent pregnancy are likely to contain

high levels of …
A LH and oestrogen.
B only FSH.
C only progesterone.
D FSH and progesterone.

1.1.6 The diagram shows the blood groups of individuals in a family.
A B
O A AB
Which statement about the genotypes of the parents is correct?
A Both parents have alleles for blood group A and B.

B Both parents have the allele for blood group O.
C Only the father has the allele for blood group O.
D Only the mother has the allele for blood group O.
1.1.7 Which ONE of the following is an effect of the sympathetic nervous

system?
A Increased heart rate

B Constricted pupils
C Decreased blood pressure
D Contraction of the bladder wall
1.1.8 The table below shows the percentages of bases in DNA samples
from various organisms.
Source of Adenine Cytosine Guanine Thymine

DNA
Human liver 30 20 20 Z
Chicken liver W 40 40 10
Dog liver 24 26 24 26
Mouse bone
marrow 23 X 26 25
Sunflower leaf 10 39 Y 12
Which ROW of the table below correctly reflects the missing data
values?
W X Y Z
A 9 24 38 30
B 10 26 39 31
C 10 26 39 30
D 10 25 38 29

1.1.9 The diagram shows a family in which some members suffer from a
disease caused by a recessive allele.
1 2
Male without the

disease
Female without the
disease
3 4 5
Male with the disease
Female with the

disease
6 7
Identify TWO family members who must be heterozygous for the

gene.
A 5 and 7
B 3 and 6
C 2 and 3
D 1 and 4
1.1.10 An investigation was carried out to determine the fertility levels of

healthy males in different age groups.
The procedure followed was as follows:

• 50 healthy males in each of the following age groups were asked
to participate: 20–29, 30–39, 40–49, 50–59 and 60–69.
• Semen was collected from each of the males.
• The number of active sperm cells present in the semen was
counted for each man in each age group and averages were
calculated.
Which ONE of the following is the dependent variable in the

investigation?
A Fitness levels of the males

B Age groups of the males
C Number of active sperm cells
D Amount of semen (10 x 2) (20)

1.2 Give the correct biological term for each of the following descriptions. Write
only the term next to the question number (1.2.1–1.2.8) in the ANSWER
BOOK.
1.2.1 The type of fertilisation where the eggs are fertilised inside the body
of the animal
1.2.2 A blood vessel in the umbilical cord that transports nutrients to the
foetus
1.2.3 Organelle outside the nucleus of animal cells that contain DNA
1.2.4 The part of the ear that directs sound waves into the external auditory
canal
1.2.5 The structure in the head of a sperm containing digestive enzymes
1.2.6 The stage when secondary sexual characteristics develop in males

and females
1.2.7 The network of genetic material found in the nucleus during

interphase
1.2.8 The type of egg produced by reptiles that has extra-embryonic

membranes (8 x 1) (8)
1.3 Indicate whether each of the descriptions in COLUMN I applies to A ONLY,

B ONLY, BOTH A AND B or NONE of the items in COLUMN II. Write A only,
B only, both A and B or none next to the question numbers (1.3.1 to 1.3.3)
in the ANSWER BOOK.
COLUMN I COLUMN II
1.3.1 Discovered the structure of the DNA A: Watson and Crick
molecule B: White and Dart
1.3.2 Reproductive strategy in birds where A: Precocial
hatchlings are helpless and unable to B: Altricial
move and feed themselves
1.3.3 Type of inheritance where both A: Incomplete dominance
alleles are expressed equally in the B: Complete dominance
phenotype
(3 x 2) (6)

1.4 The diagram below represents the results of a paternity investigation. It was
determined that the three children were siblings (brothers or sisters) and share
the same biological mother. Their mother is Adult B.
1.4.1 Name the technique used to obtain the results shown above. (1)
1.4.2 Which ONE of the adults is the children’s father? (1)
1.4.3 Give a reason for your answer to QUESTION 1.4.2. (2)
1.4.4 Which of the children are identical twins? (2)
1.4.5 State TWO other uses of the technique mentioned in

QUESTION 1.4.1. (2)

1.5 In rabbits, fluffy tails (F) are dominant to unfluffy tails (f). Brown fur (B) is
dominant to white fur (b). Two rabbits who are heterozygous for both traits are
crossed.
The Punnet diagram below shows the possible gametes produced by each
parent.
FB Fb fB fb
FB FFBB X FfBB FfBb
Fb FFBb FFbb FfBb Ffbb
fB FfBB FfBb ffBB Y
fb FfBb Ffbb ffBb ffbb
1.5.1 (a) State the type of cross represented above. (1)
(b) Give a reason for your answer to QUESTION 1.5.1(a). (1)
1.5.2 How many offspring have unfluffy tails and white fur? (1)
1.5.3 Give the genotype of the parent rabbits who were crossed. (1)
1.5.4 Identify the:
(a) Phenotype of offspring X (1)
(b) Genotype of offspring Y (1)
1.5.5 Give the proportion of offspring that could have fluffy tails. (2)
TOTAL SECTION A: 50

SECTION B
QUESTION 2
2.1 The diagram below represents one strand of a DNA molecule.
Y Z
T A C A A G C
A G
2.1.1 Identify:
(a) Sugar Y (1)
(b) Molecule Z (1)
2.1.2 Describe the process by which DNA makes a copy of itself. (6)
2.1.3 The table below shows the mRNA codons and the amino acids they
code for:
mRNA codon Amino Acid

AAG Lys
AGU Ser
AUG Met
UAC Tyr
UCA Ser
UGC Cys
UUC Phe
Use the table above to write down the correct sequence of amino acids
coded for from left to right, by the DNA strand shown above. (3)
2.1.4 During DNA replication, a mutation occurred in the first DNA triplet from
the DNA molecule given above, changing from TAC to TTC.
Describe the effect of this mutation on the protein formed. (4)

2.2 The diagram shows a pair of homologous chromosomes.
E E
a A
B B
D d
2.2.1 Identify:
(a) Position 1 (1)
(b) Structure 2 (1)
2.2.2 State whether an individual with these chromosomes is homozygous

or heterozygous with regards to the gene represented as A. (1)
2.2.3 Give a reason for your answer in QUESTION 2.2.2. (1)
2.2.4 Explain why these homologous chromosomes are similar but not
identical. (3)

2.3 The diagram shows some of the stages in human reproduction, from ovum
(egg) to foetus.
Foetus
ovum
1 2 3 4 5
2.3.1 Identify reproductive structure at:
(a) 3 (1)
(b) 4 (1)
2.3.2 Name the process that is taking place at stage 2. (1)
2.3.3 Where in the body does the process at stage 2 occur? (1)
2.3.4 Describe the process responsible for the formation of the reproductive
cell shown at stage 1. (6)
2.3.5 Describe TWO ways in which the foetus is protected. (2)
2.4 Piebaldism is a genetic condition which is characterised by a person having a

white patch of hair. Piebaldism is controlled by a single dominant allele (H).
The diagram below shows a person with Piebaldism.
A man with a white patch of hair and a woman with a white patch of hair have
two children:
- The first child was born without a white patch of hair.
- The second child was born with a white patch of hair
Use a genetic cross to show the possibility of producing the phenotypes of the
children as described above. (6)

2.5 The diagram shows the chromosomes in one human cell.
1 2 3 4 5 6
7 8 9 10 11 12
13 14 15 16 17 18
19 20 21 22 XX
2.5.1 Name the type of diagram shown above. (1)
2.5.2 Identify the chromosomes labelled 1–22. (1)
2.5.3 State whether the individual shown is a male or a female. (1)
2.5.4 Give a reason for your answer to QUESTION 2.5.3. (2)
2.5.5 Describe how this human cell ended up with the number of
chromosomes shown at position 21. (5)
[50]

QUESTION 3
3.1 The diagram below represents a phase during meiosis.
3.1.1 Identify structures labelled:
(a) W (1)
(b) X (1)
3.1.2 Identify the phase shown. (1)
3.1.3 Give a reason for your answer in QUESTION 3.1.2. (1)
3.1.4 State the number of chromosomes that each daughter cell will contain
at the end of meiosis. (1)
3.1.5 Give evidence from the diagram which indicates that the resulting
daughter cells will be genetically different. (1)
3.1.6 Explain the significance of the daughter cells being genetically

different. (2)

3.2 The graph below shows the changes in the levels of hormones in the menstrual
cycle of a female.
Key
B X
Y
A Z
Level of
Oestrogen
hormone
0 7 14 21 28
Time (in days)
3.2.1 Identify events in the menstrual cycle labelled:
(a) A (1)
(b) B (1)
3.2.2 Name the hormone:
(a) X (1)
(b) Z (1)
3.2.3 State the function of hormone X. (1)
3.2.4 Explain, the effect of the decrease in the level of hormone Z to the level
shown in the graph above. (5)

3.3 The diagram below shows part of the human ear.
3.3.1 Give the LETTER and NAME of the part that:
(a) Equalises pressure between the outer ear and the middle ear (2)
(b) Absorbs excess pressure waves in the inner ear (2)
3.3.2 Give a function of the part labelled F. (1)
3.3.3 Explain the significance of the arrangement of the structures labelled A. (3)
3.4 Describe the path of an impulse in a reflex arc during a reflex action. (7)

3.5 Scientists investigated the effect of age on focusing distance of the eye.
The method they used is described below:

• Volunteers of different ages had their eyes tested
• Three individuals from each selected age were used
• Each volunteer was asked to read from a book
• The book was moved closer to their eyes
• When the words became out of focus, the distance was recorded
The results of the investigation are shown in the table below:
Distance (mm) Average

Age of Individual 1 Individual 2 Individual 3 distance
volunteers (mm)
40 256 261 257 258
45 282 275 280 279
50 292 301 297 X
55 311 309 307 309
3.5.1 Calculate the average distance for the volunteers aged 50 indicated as
X in the table. (3)
3.5.2 (a) Name the process by which the eye is able to bring about a clear
image when the book is moved closer to the eyes of the
individuals. (1)
(b) Describe the process mentioned in QUESTION 3.5.2(a). (5)
3.5.3 Use the data from the table to plot a bar graph showing the average
focusing distance of volunteers aged 40, 45 and 55. (6)
3.5.4 State the conclusion of this investigation. (2)

[50]
TOTAL SECTION B: 100

GRAND TOTAL: 150

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NATIONAL

This question paper consists of 16 pages.

INSTRUCTIONS AND INFORMATION

Read the following instructions carefully before answering the questions.

1. Answer ALL the questions.

2. Write ALL the answers in your ANSWER BOOK.

3. Start the answer to EACH question at the top of a NEW page.

5. Present your answers according to the instructions of each question.

6. Do ALL drawings in pencil and label them in blue or black ink.

7. Draw diagrams, tables or flow charts only when asked to do so.

9. Do NOT use graph paper.

11. Write neatly and legibly.

Copyright reserved Please turn over

1.1.1 The central nervous system is made up of the …

A autonomic and peripheral nervous systems.

1.1.3 Where are sperm cells in humans temporarily stored?

1.1.4 A patient experiences slight visual and speech disturbance after a

1.1.5 Contraceptive pills which prevent pregnancy are likely to contain

Copyright reserved Please turn over

1.1.6 The diagram shows the blood groups of individuals in a family.

Which statement about the genotypes of the parents is correct?

A Both parents have alleles for blood group A and B.

1.1.7 Which ONE of the following is an effect of the sympathetic nervous

A Increased heart rate

Source of Adenine Cytosine Guanine Thymine

Copyright reserved Please turn over

Male without the

Female with the

Identify TWO family members who must be heterozygous for the

1.1.10 An investigation was carried out to determine the fertility levels of

The procedure followed was as follows:

Which ONE of the following is the dependent variable in the

A Fitness levels of the males

Copyright reserved Please turn over

1.2.5 The structure in the head of a sperm containing digestive enzymes

1.2.6 The stage when secondary sexual characteristics develop in males

1.2.7 The network of genetic material found in the nucleus during

1.2.8 The type of egg produced by reptiles that has extra-embryonic

1.3 Indicate whether each of the descriptions in COLUMN I applies to A ONLY,

Copyright reserved Please turn over

1.4.2 Which ONE of the adults is the children’s father? (1)

1.4.3 Give a reason for your answer to QUESTION 1.4.2. (2)

1.4.4 Which of the children are identical twins? (2)

1.4.5 State TWO other uses of the technique mentioned in

Copyright reserved Please turn over

FB FFBB X FfBB FfBb

Fb FFBb FFbb FfBb Ffbb

fB FfBB FfBb ffBB Y

fb FfBb Ffbb ffBb ffbb

1.5.1 (a) State the type of cross represented above. (1)

(b) Give a reason for your answer to QUESTION 1.5.1(a). (1)

1.5.4 Identify the:

(a) Phenotype of offspring X (1)

(b) Genotype of offspring Y (1)

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2.1 The diagram below represents one strand of a DNA molecule.

(a) Sugar Y (1)

(b) Molecule Z (1)

mRNA codon Amino Acid

Describe the effect of this mutation on the protein formed. (4)

Copyright reserved Please turn over

2.2 The diagram shows a pair of homologous chromosomes.

(a) Position 1 (1)