40033832 STERILE GEL

intramuscularly. Injectable
apart subcutaneously or
• Administer two 1-mL doses 3 weeks
DAPP +L4

GEL
INJECT
6 +
WEEKS

Injectable

Vaccine

EXTENDED TAB
for vaccination.
To Reconstitute:
DAPP +L4

with the sterile gel

MODIFIED LIVE VIRUS

Rehydrate the vaccine

STERILE GEL
STERILE GEL

Grippotyphosa-
Injectable

Pomona Bacterin
DAPP +L4

Canine Distemper-
Adenovirus Type 2-

Injectable
Leptospira Canicola-

Icterohaemorrhagiae-

DAPP +L4

STERILE GEL
Parainfluenza-Parvovirus

FOR EASIER STORAGE & VIEWING

NO INK / NO COPY ZONE

• Pull down on this tab.

tray of vials inside top lid.

• Flip tab out and set bottom
25 Vials (1 mL)
25 Vials (1 dose)
VLN 190/PCN 47K1.20
Zoetis Inc.
Kalamazoo, MI 49007, USA
• Store at 2°–8°C. Do not freeze. DAPP +L4
• See back of card for complete
directions and precautions. Injectable

STERILE GEL

AWC Representative Plant Name / Code

Artwork Center: US G. Woods JR Lincoln/US12

QN / Project No. FG Material No. New Material No. Description

200009938 10024432 40033832 TRAY CARD VANGUARD DAPP/L4 1DS 1ML 25CT
DIR No. / Version No. Speciÿcation / DWG Old Material No. Countries
512487 /00 Z14-803715 NA US
Dimensions Colors
18.125” x 5.468” 4
Color Process PMS 158 PMS 301 Dieline No Varnish
Additional Info.

Visual Code Bars: 7, 9 Version No. Date

v3 40033832.pdf 1 3/9/21 9:14 AM
DAPP+L4 Injectable
This product has been shown to be effective for the vaccination of
healthy dogs 6 weeks of age or older against canine distemper virus
(CDV), canine adenovirus type 1 (CAV1), canine adenovirus type
2 (CAV2), canine parainfluenza virus (CPIV), canine parvovirus (CPV),
canine parvovirus type 2c (CPV2c), Leptospira canicola,
L. grippotyphosa, L. icterohaemorrhagiae, and L. pomona. Duration of
immunity has not been established. For more information regarding
efficacy and safety data, see productdata.aphis.usda.gov.
Vanguard DAPP+L4 contains attenuated strains of CDV, CAV2, CPIV, CPV,
and inactivated whole cultures of the four Leptospira serovars mentioned
above. The high-titer, low-passage CPV virus in Vanguard DAPP+L4 is
highly immunogenic and capable of stimulating active immunity in the
presence of maternal antibodies. This product does not contain CPV type
2c. Cross protection against CPV type 2c was demonstrated in
vaccinated puppies challenged 5 weeks following second vaccination.
Vaccination and revaccination according to label directions have been
demonstrated (under field conditions) to result in serum antibody titers
that persist for 12-48 months against CDV (serum neutralization [SN]
titer > 1:32), CAV1 (SN > 1:16), CAV2 (SN > 1:16), CPIV (SN > 1:16), and
CPV (hemagglutination inhibition [HAI] titer > 1:80).
Directions: Aseptically rehydrate the freeze-dried vaccine with the
sterile gel provided, shake well, and administer 1 mL subcutaneously or
intramuscularly. Healthy dogs should receive 2 doses administered
3 weeks apart. The presence of maternal antibody is known to interfere
with the development of active immunity in puppies and additional
boosters will be required in most young animals. Historically, annual
revaccination with this product was recommended. The need for annual
booster vaccinations has not been established. For advice on
revaccination, consult your veterinarian or the manufacturer.
Precautions: Store at 2°–8°C. Prolonged exposure to higher
temperatures and/or direct sunlight may adversely affect potency. Do
not freeze. Sterilized syringes and needles should be used to administer
this vaccine. Do not sterilize with chemicals because traces of
disinfectant may inactivate the vaccine. Inactivate unused contents
before disposal. Contains gentamicin and thimerosal as preservatives.
This product has not been tested in pregnant animals. In case of
anaphylactoid reaction, administer epinephrine. Do not mix with other
products, except as specified above. In case of human exposure, contact
a physician.
Technical inquiries should be directed to Zoetis Inc. Veterinary Services,
(888) 963-8471.
This product has been shown to be efficacious in healthy animals. A
protective immune response may not be elicited if animals are
incubating an infectious disease, are malnourished or parasitized, are
stressed due to shipment or environmental conditions, are otherwise
immunocompromised, or the vaccine is not administered in accordance
with label directions. 40033832A&P