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SW#4 - CELL CYCLE: INTERPHASE TO MITOSIS
I. Instructions: Choose the best answer for each question. Write your answer before the number.
_________1. Which of the following is the primary function of interphase in the cell cycle?

a) Replication of DNA

b) Cell division
c) Cell growth and preparation for division

d) Protein synthesis

_________2. The G1 phase of interphase is characterized by:

a) DNA replication

b) Chromosome condensation
c) Rapid cell growth
d) Nuclear envelope breakdown

_________3. During which phase of interphase does DNA replication occur?

a) G0

b) G1
c) S phase
d) G2

_________4. What is the role of checkpoints in the cell cycle?

a) To ensure DNA replication is complete before cell division

b) To monitor cell size and nutrient availability

c) To regulate the progression of the cell cycle

d) All of the above

_________5. Mitosis is a process of:

a) Cell growth
b) Sexual reproduction
c) Cell division resulting in two genetically identical daughter cells

d) Protein synthesis
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_________6. The first stage of mitosis, prophase, is characterized by:

a) Nuclear envelope breakdown

b) Spindle fiber formation

c) Chromosome condensation

d) All of the above

_________7. During metaphase of mitosis, chromosomes align at:

a) The nuclear envelope

b) The center of the cell

c) The cell membrane

d) The poles of the cell

_________8. In anaphase, sister chromatids:

a) Condense further
b) Attach to spindle fibers

c) Separate and move towards opposite poles

d) Remain attached at the centromere

_________9. Cytokinesis is the process of:

a) Nuclear envelope breakdown

b) Chromosome separation

c) Division of the cytoplasm to form two daughter cells

d) Spindle fiber formation

_________10. The overall purpose of mitosis is:

a) Sexual reproduction
b) Growth and repair of multicellular organisms

c) Production of gametes
d) Protein synthesis

_________11. Which of the following statements is FALSE about mitosis?

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a) It results in two daughter cells with the same number of chromosomes as the parent cell.

b) It involves the duplication of chromosomes during interphase.

c) It is a continuous process without distinct stages.

d) It is essential for maintaining genetic information in new cells.

_________12. Uncontrolled cell division is a hallmark of:

a) Cancer

b) Mitosis

c) Interphase
d) Meiosis

_________13. Which organelle plays a critical role in separating sister chromatids during mitosis?
a) Ribosomes

b) Golgi apparatus

c) Endoplasmic reticulum
d) Centromere

_________14. Which of the following best describes the order of the main stages of mitosis?
a) Prophase, metaphase, anaphase, telophase, cytokinesis
b) Metaphase, prophase, anaphase, telophase, cytokinesis

c) Anaphase, metaphase, prophase, telophase, cytokinesis

_________15. The structures that attach to kinetochores on chromosomes and guide their movement
during mitosis are called:
a) Centromeres

b) Microtubules

c) Sister chromatids
d) Centrosomes

_________16. During telophase, chromosomes:

a) Further condense

b) Begin replicating
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c) Decondense and form daughter nuclei

d) Move towards the cell membrane

_________17. At the beginning of metaphase, chromosomes are aligned at the center of the cell on a
structure called:

a) Midbody
b) Metaphase plate

c) Cleavage furrow

d) Astral microtubules

_________18. During interphase, DNA replication occurs, resulting in the formation of two identical
copies of each chromosome. These copies are called:
a) Homologous chromosomes

b) Sister chromatids

c) Genes
d) Nucleotides

_________19. After DNA replication, how many chromatids does each chromosome consist of?
a) 0

b) 1

c) 2
d) It varies depending on the organism

_________20. During which stage of mitosis do sister chromatids separate and move towards
opposite poles of the cell?

a) Prophase

b) Metaphase
c) Anaphase

d) Telophase
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II. Illustrate the cell division that happens in mitosis.