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PRESCRIBED

DRUG DOSAGE,
ROUTE, CLASSIFICATIO INDICATIONS AND SPECIAL NURSING RESPONSIBILITY
FREQUENCY, AND N AND CONTRAINDICATION SIDE EFFECT/ PRECAUTION
TIMING MECHANISM OF ADVERSE REACTION
ACTION

GENERIC NAME Classification Indications Side Effect Precaution  Check doctor’s order

AMITRIPTYPLINE tricyclic Amitriptyline is indicated for the Amitriptyline can cause sedation, dry mouth, Abrupt  Observe the 12 rights of
antidepressant treatment of major depressive blurred vision, constipation, urinary retention, discontinuation administering medication
BRAND NAME (TCA) disorder, neuropathic pain, orthostatic hypotension, weight gain, sexual
migraines (as a prophylactic dysfunction, increased heart rate, cognitive should be
treatment), certain anxiety impairment, agitation, and increased risk of suicidal avoided, and  Monitoring the patient's vital signs,
LEVATE Mechanism of
disorders, and insomnia ideation or behavior (particularly in children, caution should particularly blood pressure and
Action (particularly in patients with adolescents, and young adults). The occurrence
ROUTE be taken with heart rate, as amitriptyline can affect
depression). It should only be and severity of side effects may vary from person
Amitriptyline is a activities that cardiovascular function
used under the supervision of a to person. Patients should discuss any potential
ORAL tricyclic licensed medical professional side effects with their healthcare provider. require alertness.  Monitoring the patient for signs of
antidepressant that and its use should be closely Patients with urinary retention or obstruction
FREQUENCY, AND works by increasing monitored. Adverse Reaction urinary retention  Ensuring that the patient is not taking
TIMING neurotransmitter Contraindication any other medications that could
levels in the brain or glaucoma
interact with amitriptyline
and affecting brain Amitriptyline can cause rare adverse reactions should also be
TID Amitriptyline is contraindicated in  Documenting any adverse reactions or
receptors. It leads to such as seizures, cardiac arrhythmias, monitored. It is
patients who are hypersensitive changes in the patient's condition and
improved mood and hypotension, hepatitis, jaundice, elevation of important to reporting them to the healthcare
to it or any of its components,
other symptoms of liver enzymes, bone marrow suppression,
have recently had a heart attack, discuss any provider
depression. blood disorders, and allergic reactions. It is
have severe liver or concerns with a
cardiovascular disease, angle- important to seek medical attention  Ensuring that the patient is not taking
immediately if any of these adverse reactions healthcare
closure glaucoma, urinary any other medications that could
retention or obstruction, a history occur. provider.
interact with amitriptyline
of seizures or epilepsy, or are
children under 12 years old.

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