NURS FPX 6414 Assessment 3 Tool Kit for Bioinformatics

Assessment 3: Tool Kit for Bioinformatics
Student Name
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Capella University
NURS-FPX 6414 Advancing Health Care Through Data Mining
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Prof. Name
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MAR 24, 2024
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Bioinformatics Toolkit for Enhancing Health Security
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Amidst the COVID-19 pandemic, concerns regarding health security have intensified,
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particularly among individuals who have visited healthcare facilities during the outbreak
and harbored fears of contracting the virus in such settings (Wu et al., 2020). Swift
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identification and treatment of COVID-19 infections are paramount in bolstering people’s

sense of security. Health Information Technology, encompassing Clinical Decision
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Support Systems (CDSS) and Best Practice Advisory (BPA) alerts, assumes a pivotal
role in achieving this goal (Wu et al., 2020). This article endeavors to furnish a
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comprehensive toolkit for implementing CDSS and BPA alerts.
Evidence-Based Strategies for Healthcare Policy

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The burden imposed by the COVID-19 pandemic has escalated the workload for
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healthcare professionals and significantly inflated healthcare costs. Failure to contain

the spread of the illness could pose substantial challenges for patients, healthcare
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providers, and health systems due to a shortage of medical personnel and equipment
(Moulaei, 2022). Early detection of COVID-19 infections is imperative, and optimized
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utilization of CDSS can aid physicians in making informed decisions, resulting in

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expedited and more accurate diagnoses, and containment of outbreaks (Moulaei,
2022).
In the domain of health information technology, the Affordable Care Act mandates
healthcare providers to adopt and fully leverage technology to enhance quality, patient
outcomes, and mitigate healthcare costs (Fry, 2021). A fully developed Electronic
Health Record (EHR) with Clinical Decision Support (CDS) is indispensable for a
learning health system adept at navigating the intricate healthcare landscape.
Integrated clinical decision support technologies, such as Best Practice Advisory (BPA)
alerts, augment clinical decision-making by furnishing pertinent information to clinicians
(Fry, 2021).
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Guidelines for Effective Policy Implementation
Successful policy implementation necessitates the support of key stakeholders.
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Disseminating guiding principles, norms, and policies to the entire healthcare workforce
is imperative (Akhloufi et al., 2022). Regular meetings involving physicians, nurses,
hospital administrators, nurse informaticists, and information technology specialists
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should be convened to devise an efficient CDSS and BPA alert system. These meetings
aim to enhance technology user-friendliness, minimize errors, and provide training on
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proficient technology utilization (Akhloufi et al., 2022).
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Following meetings and training sessions, implementation planning may commence,
with the development team delineating project goals. Collaboration with system vendors
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is pivotal for effective technology integration, with vendors potentially introducing a beta
version or minimum viable product for testing and feedback, leading to system
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adjustments tailored to the needs of patients and healthcare professionals (Akhloufi et

al., 2022).
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Practical Recommendations
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Stakeholder Education
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Successful technology implementation necessitates buy-in from all pertinent

stakeholders. Healthcare organizations can educate their staff on maximizing
technology potential through weekly training sessions, seminars, and webinars, while
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also addressing staff concerns (Lukowski et al., 2020). Classroom-based team training
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interventions and simulations have been shown to be advantageous for assessing

technical competence and addressing training gaps in healthcare technology use
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(Bienstock & Heuer, 2022).

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Monitoring Data to Assess Outcomes
Post successful implementation of CDSS and BPA alert systems, evaluating their
impact on COVID-19 patient outcomes is imperative. The potential of the CDSS system
to enhance health outcomes through rapid and accurate disease detection can curtail its
spread, reduce healthcare costs, and augment patient safety (Karthikeyan et al., 2021).
Saegerman et al. (2021) demonstrated that the CDSS system facilitated the prompt
identification of COVID-19 patients, aiding triage efforts in understaffed diagnostic labs
during the pandemic. This clinical decision support tool assumes a pivotal role in
managing the pandemic (Saegerman et al., 2021).
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Illustrative Example of Bioinformatics in Practice
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Clinicians can significantly abbreviate the time required to assess patients with
COVID-19 symptoms by utilizing a clinical decision support tool for diagnostic
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evaluations (Gavrilov et al., 2021). Effective quarantine of patients with COVID-19
symptoms is imperative to forestall further virus dissemination in healthcare facilities.
The CDSS system guides practitioners through a standardized COVID-19 diagnostic
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workup based on the latest recommendations, streamlining the process (Gavrilov et al.,
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2021).
The integration of CDSS systems with Best Practice Advisory (BPA) alerts confers
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several advantages, including enhanced patient and staff safety, expeditious virus
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detection, and time-saving benefits (Gavrilov et al., 2021).
Process: Before and After CDSS Implementation

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Metric Before CDSS After CDSS

Implementation Implementation
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Time to make an accurate 1-2 days 5-6 hours

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diagnosis of COVID-19
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Healthcare costs $9500 $2000
Unidentified patients in quarantine 10-20 patients 5 patients
False Negative Results 7-8 false negatives 3-4 false negatives
Conclusion
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This study explored the feasibility of employing CDSS systems in the administration and
management of COVID-19. The CDSS system’s capacity to swiftly diagnose COVID-19
patients assists healthcare professionals in containing its spread, reducing
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complications, lowering unnecessary treatment costs, abbreviating diagnostic
procedures, and enhancing clinical performance and patient outcomes.
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References (Arranged alphabetically)
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● Akhloufi, H., van der Sijs, H., Melles, D. C., van der Hoeven, C. P., Vogel, M.,
Mouton, J. W., & Verbon, A. (2022). The development and implementation of a
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guideline-based clinical decision support system to improve empirical antibiotic
prescribing. BMC Medical Informatics and Decision Making, 22(1).
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https://doi.org/10.1186/s12911-022-01860-3
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● Bienstock, J., & Heuer, A. (2022). A review on the evolution of simulation-based

training to help build a safer future. Medicine, 101(25), e29503.
https://doi.org/10.1097/MD.0000000000029503
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● Fry, C. (2021). Development and evaluation of best practice alerts: Methods to

optimize care quality and clinician communication. AACN Advanced Critical
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Care, 32(4), 468–472. https://doi.org/10.4037/aacnacc2021252

● Gavrilov, D., Kuznetsova, T., Gusev, A., Korsakov, N., & Novitskiy, R. (2021).
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Application of a clinical decision support system to assess the severity of the new
coronavirus infection COVID-19. European Heart Journal, 42(Supplement_1).
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https://doi.org/10.1093/eurheartj/ehab724.3054
● Karthikeyan, A., Garg, A., Vinod, P. K., & Priyakumar, U. D. (2021). Machine
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learning-based Clinical Decision Support System for early COVID-19 mortality

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prediction. Frontiers in Public Health, 9.
https://doi.org/10.3389/fpubh.2021.626697
● Lukowski, F
., Baum, M., & Mohr, S. (2020). Technology, tasks and training – Evidence on the
provision of employer-provided training in times of technological change in Germany.
Studies in Continuing Education, 1–22. https://doi.org/10.1080/0158037x.2020.1759525
● Moulaei, K. (2022). Diagnosing, managing, and controlling COVID-19 using

Clinical Decision Support systems: A study to introduce CDSS applications.
Journal of Biomedical Physics and Engineering, 12(02).
https://doi.org/10.31661/jbpe.v0i0.2105-1336
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● Saegerman, C., Gilbert, A., Donneau, A.-F., Gangolf, M., Diep, A. N., Meex, C.,
Bontems, S., Hayette, M.-P., D’Orio, V., & Ghuysen, A. (2021). Clinical decision
support tool for diagnosis of COVID-19 in hospitals. PLOS ONE, 16(3),
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e0247773. https://doi.org/10.1371/journal.pone.0247773
● Wu, G., Yang, P., Xie, Y., Woodruff, H. C., Rao, X., Guiot, J., Frix, A.-N., Louis,
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R., Moutschen, M., Li, J., Li, J., Yan, C., Du, D., Zhao, S., Ding, Y., Liu, B., Sun,
W., Albarello, F., D’Abramo, A., & Schininà, V. (2020). Development of a clinical
decision support system for severity risk prediction and triage of COVID-19
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patients at hospital admission: an international multicentre study. European
Respiratory Journal, 56(2). https://doi.org/10.1183/13993003.01104-2020
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Assessment 3: Tool Kit for Bioinformatics

NURS-FPX 6414 Advancing Health Care Through Data Mining

identification and treatment of COVID-19 infections are paramount in bolstering people’s

comprehensive toolkit for implementing CDSS and BPA alerts.

Evidence-Based Strategies for Healthcare Policy

healthcare professionals and significantly inflated healthcare costs. Failure to contain

utilization of CDSS can aid physicians in making informed decisions, resulting in

Successful policy implementation necessitates the support of key stakeholders.

adjustments tailored to the needs of patients and healthcare professionals (Akhloufi et

Successful technology implementation necessitates buy-in from all pertinent

interventions and simulations have been shown to be advantageous for assessing

(Bienstock & Heuer, 2022).

detection, and time-saving benefits (Gavrilov et al., 2021).

Process: Before and After CDSS Implementation

Metric Before CDSS After CDSS

Time to make an accurate 1-2 days 5-6 hours

Unidentified patients in quarantine 10-20 patients 5 patients

False Negative Results 7-8 false negatives 3-4 false negatives

● Bienstock, J., & Heuer, A. (2022). A review on the evolution of simulation-based

● Fry, C. (2021). Development and evaluation of best practice alerts: Methods to

Care, 32(4), 468–472. https://doi.org/10.4037/aacnacc2021252

learning-based Clinical Decision Support System for early COVID-19 mortality

● Moulaei, K. (2022). Diagnosing, managing, and controlling COVID-19 using

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