TREATMENT/ INFUSION Generic Name: Cefuroxime Brand Name: Zinacef Classification: Anti-infective: 2nd gen.

cephalosporin Dosage : 75mg TIV ANST(-) Q8

ACTION/ KINETICS Cefuroxime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.

INDICATION Treatment for Upper and Lower respiratory tract infections, Genitourinary tract infections, Genitourinary tract infections, UTI, septicemia, gonorrhea, bone and joint infection

CONTRAINDICA TION Hypersensitivity to cephalosporin antibiotics.

NURSING RESPONSIBILIT IES CV: phlebitis, Assess for thrombophlebitis hypersensitivi Hematologic: ty reactions hemolytic Monitor signs anemia, of adverse thrombocytopeni reactions a, transient Determine neutropenia, history of eosinophilia hypersensitivi CNS: Dizziness, ty reactions headache, to fatigue, cephalosporin paresthesia, s, penicillins, fever, chills, and history of confusion allergies, GI: Diarrhea, particularly to nausea, drugs, before vomiting, therapy is anorexia, initiated. glossitis, Inspect IM bleeding, and IV increased AST, injection sites ALT, bilirubin, frequently for LDH, alkaline signs of phosphatase, phlebitis. abdominal pain, Report onset

SIDE EFFECT

loose stools, flatulence, heartburn, stomach cramps, colitis, jaundice GU: vaginitis, pruritus, candidiasis, increased BUN, nephrotoxicity, renal failure, pyuria, dysuria, reversible interstitial nephritis

of loose stools or diarrhea. Although pseudomemb ranous colitis. Monitor I&O rates and pattern: Especially important in severely ill patients receiving high doses. Report any significant changes.

Generic Name: Acetylcysteine Brand Name: Acetadote Classification: Mucolytic Dosage :

Acetylcysteine may decrease the viscosity of secretions by splitting of disulphide bonds in mucoproteins. It also promotes the

Adjunct in the treatment of chronic emphysema, emphysema with bronchitis, tuberculosis, acute

Sensitivity to the drug.

Flushing, fever, stomatitis, nausea, vomiting, rhinorrhoea, bronchospasm, anaphylactoid reactions,

Document conditions likely to cause congestion and wheezing. Position to

600mg in 1 glass of H2O OD

detoxification of an intermediate paracetamol metabolite which is used in the management of paracetamol overdosage

bronchopulmonary disease. Andidote in paracetamol poinsoning to reduce or prevent hepatotoxicity

rashes. Rarely, blurred vision, bradycardia, syncope, thrombocytopeni a, convulsions.

Generic Name: Ipratropium

Ipraprotium bromide:Anticholine rgic, chemically

For the management of

Patients with cardiac tachyarrhythmias

Headache,dizzin ess, dryness of mouth, throat

facilitate removal of secretions. If unable to cough up secretions, provide suction. Advise the patients relative to report changes in sputum color, consistency, characteristic s or new onset fever. Also avoid any triggers that may stimulate bronchospas m (i.e. dust, chemical, cold air). Monitor the patients vital signs, noting

Bromide + Salbutamol Sulfate Brand Name: Combivent Classification: Adrenergic beta2agonist, sympathomimeti c, bronchodilator Dosage : 1 Neb Q6

Generic Name: Clarithromycin Brand Name: Clariget Classification: Macrolide antibiotic Dosage : 250mg 1 tab

related to atropine, which blocks vagally mediated reflexes by antagonizing the action of acetylcholine. Causes bronchodilation and inhibits secretion from serous and seromucous glands lining the nasal mucosa. Salbutamol:Stimulat es beta-2 receptors of bronchioles to produce bronchodilation Inhibits protein synthesis in susceptible bacteria, causing cell death.

bronchospasm in patients suffering from chronic obstructive pulmonary disease (COPD) who requires regular treatment with both ipratropium and salbutamol.

, hypertrophic obstructive cardiomyopathy and patients with a history of hypersensitivity to any of its components or to atropine or its derivatives.

irritation, nausea, vomiting, GI upset palpitations, chest pain, blurred vision, cough, nasal stuffiness, sleep disturbances palpitation, urinarty retention

hypotension and an irregular or abnormal pulse. Maintain a quiet, comfortable environment to minimize anxiety and perhaps decrease palpitations.

Treatment of upper and lower respiratory infections, skin and skin-structure infections, disseminated mycobacterial infections, active duodenal ulcer,

Contraindicated with Hypersensitivity to clarithromycin, erythromycin, or any macrolide antibiotic. Use cautiously with colitis,

CNS: Assess Dizziness, patient for headache, infection vertigo, (vital signs, somnolenc sputum, e, fatigue urine, and stool) at GI: beginning of Diarrhea, therapy. abdominal pain, Remind the

BID

acute otitis media, acute maxillary sinusitis, mild to moderate communityacquired pneumonia in adults

hepatic or renal impairment, pregnancy, lactation.

nausea, dyspepsia, flatulence, vomiting, melena, pseudome mbranous colitis Other: Superinfec tions, increased PT, decreased WBC

patient that some side effects may occur: Stomach cramping, discomfort, diarrhea; fatigue, headache Obtain specimens for culture and sensitivity before initiating therapy. Instruct patient to take medication around the clock and to finish the drug completely as directed, even if feeling

better. Advise patient to Report severe or watery diarrhea, severe nausea or vomiting, rash or itching, mouth sores. Instruct the patient to notify health care professional if symptoms do not improve within a few days. Generic Name: Pizotifen + MVC Brand Name: Mosegor Vita Classification: Watch out for side effects

Pizotifen is a sedating antihistamine with strong serotonin antagonist and weak antimuscarinic

Underwt due to lack of appetite associated w/ vit B deficiency secondary to impaired dietary intake or

Pregnancy & lactation.

Sedation; rarely dizziness, dry mouth, constipation

Appetite Enhancers / Antimigraine Preparations Dosage : 1 cap OD

properties. It also antagonises the action of tryptamine. Pizotifen is a serotonin antagonist acting mainly at the 5-HT1, 5-HT2A and 5HT2C receptors. It also has some activity as an antihistamine.

absorption; nervous disorders in puberty (anorexia nervosa) old age when prevention of deficiency of B-group vit is indicated.