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Home / Health / Internal Organ Health / About the Kidneys / Kidney Transplant Donor Requirements
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GENERAL REQUIREMENTS
The University of California San Francisco Medical Center requires donors to be between the ages of 18 and 65. Donors must be reasonably fit nonsmokers. Transplant centers often reject overweight volunteers until they lose weight. Donors need not be related to the recipient. Surgeons perform thousands of transplants every year between nonrelatives.
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BLOOD TYPE
An ideal donor has either the same blood type as the recipient or has type O blood, which is safe for any recipient. The Rh factor does not matter. Rh factors are immunological markers found in blood that are characterized as positive or negative. For example, a type A negative donor can give a kidney to an type A positive recipient. In some situations, a kidney donor may be willing to donate to a particular person, such as a friend or relative, but cannot do so because he is a poor match. In these cases, donors should explore paired donation. Through paired donation, a poorly matched donor can donate to a more suitable recipient, and in exchange, his friend or relative receives a kidney from a different donor, one who is also poorly matched to a particular candidate.
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TISSUE MATCHING
A prospective donor should also have a close tissue match with the recipient. Doctors base this match on six different histocompatibility antigens, immune response markers that characterize the tissue. Doctors determine histocompatibility antigens of prospective donors using a simple blood test. Perfect matching is not required, but some matches are better than others. If a prospective donor is excluded because of an unsuitable tissue match, paired donation is, again, a possible option.
PHYSICAL EXAMINATION
Donors should be free from medical issues that are risks for donation and transplantation. For example, a common medical exclusion for a donor is hypertension. Doctors also evaluate possible cardiovascular and kidney problems because these would exclude someone from donating, as would a prior history of some cancers. Other exclusions include diabetes, intravenous drug use, and certain infectious diseases—hepatitis, for example. Donors who are excluded for medical reasons can often be reevaluated once the condition has resolved. Kidney Treatment Options
PSYCHOLOGICAL EVALUATION
Prospective donors also undergo psychological evaluations to confirm that they are free from any mental health issues that would make the procedure risky. For example, donors who are mentally unstable are not good candidates because they may be unable to care for themselves properly after surgery. Physicians also make an effort to select donors who would not be psychologically harmed if a recipient ultimately lost the donated kidney. Cons of Organ Donation
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REFERENCES
Mayo Clinic: Kidney Transplant University of Maryland Medical Center: Living Kidney Donor Frequently Asked Questions University of California San Francisco Medical Center: Living Donors National Kidney Foundation: Living-Donor Kidney Transplants U.S. Department of Health and Human Services: Statistics MyPlate Article reviewed by Nancy Jacoby Last updated on: Dec 20, 2011 MyPlate D Target Heart Rate
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